Montag, 19. Januar 2009

professor position in Texas

We are writing to request your assistance in identifying qualified applicants at the Assistant, Associate, or Full Professor levels for a tenure track faculty position in the area of Macromolecular NMR Spectroscopy in the Department of Biochemistry at the University of Texas Health Science Center in San Antonio. This is part of our efforts to expand the structural biology program we have built over the past decade, including groups in NMR Spectroscopy (A. Hinck), X-ray crystallography (P. J. Hart, R. Sousa, C. Kim), and membrane biophysics (N. Robinson and B. Nicholson).

Applicants are expected to have strong backgrounds in both theoretical and experimental aspects of modern NMR spectroscopy as applied to biological macromolecules. The successful applicant will be appointed as a full-time tenure-track faculty member and will have preferential access to state-of-the-art equipment available within, and operated by, the Department, including four-channel Bruker AV 500, 600, and 700 MHz NMR spectrometers, together with high sensitivity cryogenically cooled probes for the 600 and 700 MHz spectrometers (see http://nmr.uthscsa.edu/). The NMR Facility, along with a state-of-the-art X-ray crystallography facility (including a Rigaku MIcroMax 007HF generator fitted with Varimax optics and R-AXIS HTC detectors, as well as robotic crystallization and imaging stations), analytical ultracentrifugation (including developmental machines for fluorescent and multi-wavelength detection), dynamic light scattering, surface plasmon resonance, and mass spectrometry are all operated as University Core Facilities (http://research.uthscsa.edu/) within the Department (see http://biochem.uthscsa.edu). Additional shared facilities for microcalorimetry (DSC and ITC), stopped flow and high pressure spectroscopy and circular dichroism are also available within, and operated by, the Department.

In addition to the extensive access to shared facilities both within and beyond the department, the successful candidate will be provided a generous start-up package, and newly renovated lab and office space adjacent to the NMR Facility. Candidates will be expected to develop, or bring with them (in the case of hires at the more senior level) a vigorous, externally funded, research program at the cutting edge of structural biology, and contribute to teaching in the graduate, medical and/or dental curricula. New faculty will also be encouraged to be actively involved in future recruiting and the continued growth of the Department, which has added seven new primary faculty in the last four years. The Department of Biochemistry has a strong commitment to mentorship of both junior and more senior faculty, with multiple opportunities for help in the preparation, critique, and submission of grants.

As a place to live, San Antonio offers a rich multicultural environment, a temperate climate, and a very reasonable cost of living, leading it to be the fourth fastest growing metropolitan areas in the country. There are also excellent educational and recreational opportunities, with San Antonio serving, along with Austin, as the gateway to the Texas Hill Country with its rolling hills, limestone caverns, hiking trails and wineries.

Applicants should submit, along with their cover letter, a curriculum vitae, a 2-3 page summary of past and proposed research, and names and contact information of at least three references to the address below. The applicant should also ask each referee to submit either electronic or hard copy reference letters to the same address.

Ms. Esther L. James
Department of Biochemistry, MC 7760
Allied Health Building Room 5.206
University of Texas Health Science Ctr. at San Antonio
7703 Floyd Curl Dr.
San Antonio, TX 78229-3900 U.S.A.
Tel: (210) 567-3772
Fax: (210) 567-6595
jamese@uthscsa.edu

Any questions concerning the position should be addressed to
Professor A.
Hinck (hinck@uthscsa.edu).

Thank you for your kind assistance.

Professor Andrew P. Hinck
Chair, NMR Search Committee

Professor Bruce J. Nicholson
Chair, Department of Biochemistry

Andrew P. Hinck, Professor
Department of Biochemistry, MC 7760
University of Texas Health Science Center at San Antonio
San Antonio, TX 78229-3900
office phone: 210-567-8780
lab phone: 210-567-8700
mobile phone: 210-725-4438
office fax: 210-567-8778
email: hinck@uthscsa.edu

Postdoctoral Position Michigan

Postdoctoral Position:
Solution and/or Solid-state NMR Spectroscopy of Membrane Proteins
University of Michigan

The lab of Ayyalusamy Ramamoorthy at the University of Michigan (Ann Arbor, USA) has an immediate opening for a postdoctoral fellow to work on one or all of the following projects:
(1) Structure and Dynamics of Membrane Proteins using solution and solid-state NMR.
(2) Biophysical studies on the structure and membrane toxicity of amyloid peptides.
(3) Develop solid-state NMR Techniques and apply to study chemical and biological materials.
Excellent NMR (400 and 600 Varian solid-state NMR, 600 Bruker, 800 Varian, and 900 Bruker) and other biophysical/ biochemical facilities are available at Michigan. Please visit the Ramamoorthy lab website to see recent publications from our research group.
Excellent candidates should send a CV to:

Prof. Ayyalusamy Ramamoorthy,
Biophysics and Chemistry,
University of Michigan,
Ann Arbor, MI 48109-1055, USA
Phone: (734)647-6572
e-mail: ramamoor@umich.edu

Lab web site: www.umich.edu/~ramslab

Doctoral Fellowship in Hyperpolarized Magnetic Resonance Imaging Technologies

Hyperpolarized Magnetic Resonance is a revolutionary and promising technique
with a proven potential in biomedicine and biochemistry. Based on Dynamic
Nuclear Polarization (DNP), a low-temperature technique used to increase the
nuclear spin order for particle physics experiments in which the Paul Scherrer
Institute is one of the world’s leading institutions, hyperpolarization leads
to an improvement in signal-to-noise ratio on the order of 10’000 times. It
allows for the detection of tiny amounts of biological substances in vivo and
to follow the metabolic pathways of chosen molecules.

Two unique hyperpolarizers have been developed within the Swiss DNP Initiative
regrouping several departments of the EPFL and the Paul Scherrer Institute. The
Center for Biomedical Imaging (CIBM, http://www.cibm.ch) provides access to two
high-field animal MRI systems, one working at 9.4T and the other at 14.1T. One
of the hyperpolarizers is currently coupled to the 9.4T scanner. For further
information on our Initiative, see http://sdnpi.epfl.ch.

The aim of the proposed project is to improve and further develop the Dynamic
Nuclear Polarization technology for applications in biomedical imaging. The
project will involve experimental work with world-class magnetic resonance
instrumentation.

We are seeking for a candidate with a background in Physics or Chemistry who is
interested in biological and biomedical applications. The candidate will have
the opportunity to interact with researchers involved in Particle Physics,
Chemistry, Biology and Biomedicine. The biomedical part of the project will be
performed at the CIBM while several fundamental DNP developments will take
place at the Paul Scherrer Institute.

If you are interested in this position, please send your resume and a cover
letter to arnaud.comment@epfl.ch.

Mittwoch, 10. Dezember 2008

Research/Teaching position

Research/Teaching position available in Marseille, Southern France.

This opening concerns a new kind of tenured position designed for
outstanding young scientists. The successful candidate will profit of a
reduced (-2/3) teaching load and of an increased (+30%) salary for a
period of 5 years, renewable once.


The research will concern an NMR methodology based on solid-assisted
diffusion measurements for the analysis of mixtures of small molecules,
which has shown comparable or even superior separation potential with
respect to chromatography. The candidate will be charged of extending
the methodology with a special attention to metabolomics study. Required
competences are in methodological high-resolution NMR, particularly in
fast acquisition methods. Knowledge of chemometrics would be an
advantage.


Deadlines: Non-French candidates are welcome. However, candidates must
have succesufully enrolled in the French qualification list for teaching
positions. The deadline for application to this list is December
22nd 2008.


Contact: Please send questions, CV and reference letters to Stefano
Caldarelli s.caldarelli@univ-cezanne.fr

References:
- Simplified Analysis of Mixtures of Small Molecules by
Chromatographic NMR Spectroscopy, Guilhem Pages, Corinne Delaurent, and
Stefano Caldarelli, Angew. Chem. 2006, 45 , 5950-5953
- Chomatographic NMR in NMR solvents, C. Carrara, G. Excouffier, C. Delaurent,S. Viel, S.
Caldarelli J. Magn. Reson. 2008, 194, 303-306

Post Doctoral Position

Post-doc position available in 2009 at IRCELYON, Villeurbanne, FRANCE

Development of NMR methodologies to study zeolite crystallization

The following project is part of the CADENCED programme between the King Abdullah University of Science & Technology (KAUST) Catalysis Center of Excellence and the ICE partnership (IFP/CNRS/ENS Lyon).

Context

Hydrothermal synthesis of microporous catalytic materials occurs through a very complex and poorly understood mechanism. As a result, since the first descriptions of zeolites syntheses at the end of the 19^th century like Levynite's synthesis by St. Claire Deville in 1862, trial and error has usually been applied to obtain novel catalytic materials. Although structure direction by organic ‘templates’(or Structure Directing Agents, SDA) is an essential route to the preparation of many porous catalytic materials, it remains a challenge to choose a specific template for a desired topology. The understanding of organic/inorganic interactions in (alumino)silicate gels is of primary importance to understand the templating role of molecules in zeolite synthesis. NMR is one of the best tools to study interactions at the molecular level, both in the liquid and solid states.

Project

The 12 months project will be devoted to the development of NMR techniques capable of giving information on the nature and structure of assemblies formed at the early stages of the zeolite growth. REDOR techniques (^29 Si-{1H}, ^27 Al-{1H},…) as well as correlation sequences (CP/MAS, HECTOR, COSY,…) will have to be adapted to the particular case of zeolite gels and precursors.

Experimental research will be carried out at IRCELYON (Villeurbanne, France) on a Bruker DSX 400 spectrometer equipped with various variable temperature probes. NMR developments will be used, in addtion to more conventional NMR techniques, to describe the template/(alumino)silicate species and to estimate distances in synthesis gels. This work will be done in collaboration with a PhD student working more specifically on systems containing N,N,N,N',N',N'-hexamethyl-1,6-hexanediammonium (or diquat-6) molecules.

Profile

Candidates should have a PhD in Chemistry or Physics, with a
specialization in Solid State NMR. Experience in the development of
NMR tools are also required. The candidate should also have excellent
writing and communications skills in English.

Contact

Please, send your candidacy letter, CV and recommendation letters to:

Dr Alain TUEL
Institut de Recherches sur la Catalyse et l'Environnement de Lyon (IRCELYON)
UMR 5256 CNRS-Université de Lyon1
2 avenue Albert Einstein
69626 Villeurbanne Cedex France

E-mail : alain.tuel@ircelyon.univ-lyon1.fr

Opportunity in Montpellier

The Center for Structural Biochemistry in Montpellier (a French research institute supported by INSERM, CNRS and the University of Montpellier) is interested in identifying candidates to support in the National Research Entrance Examination (Concours) at CNRS and INSERM, the French national research agencies. Our priorities involve establishing new research groups in biological atomic force microscopy and solid state NMR applied to biological systems. The limit for CNRS and INSERM applications being in January, interested parties should submit a CV, research plan and letters of recommendation to the CBS (Catherine.royer@cbs.cnrs.fr) prior to January 1st.

Postdoc position on low-field NMR

The SpinChemPhotoChem group (www.cidnp.net) of the Leiden Institute of Chemistry invites applications for a

Postdoc position on low-field NMR (up to 3 years).

With financial support of the biological section of the Dutch Science Organisation (NWO ALW), we aim to study the solid-state photo-CIDNP effect at low magnet fields. It is intended to build up a low-field NMR spectrometer and to combine it with the existing optical equipment. Aim of the project is to investigate the occurrence of the solid-state photo-CIDNP effect at low magnetic fields.

The solid-state photo-CIDNP effect has been observed in various photosynthetic reaction centres (Diller at al. 2007 PNAS 104, 12843-12848; Roy et al. 2008 Biochemistry 47, 4629?4635) as strong enhancement of NMR signals (Prakash et al. 2005 JACS 127, 14290-14298 and 2006 JACS 128, 12794-12799). The mechanism of this effect is now understood in the high-field limit (Daviso et al., submitted). It is now planned to extend this studies to evolutionary relevant low fields.

Interested candidates should have a strong background in NMR, preferably in low-field NMR, knowledge of optical methods is desirable, interest on electron-nuclear spin dynamics and the ability to work independently within the network. The postdoc would be encouraged to build up his/her own line of research.

The project can start immediately but should be starting within 2009. The deadline for applications is the 1 Feb. 2009.

For information and application, please contact:
Dr. Jörg Matysik
j.matysik (at) chem.leidenuniv.nl
tel.: +31-71-527 4198




***************************************************
Dr. Joerg Matysik
Leiden Institute of Chemistry, University of Leiden
PO Box 9502, 2300 RA Leiden (mail)
Einsteinweg 55, 2333 CC Leiden (visit/courier)
The Netherlands
Tel.: +31-71-527-4198
Fax: +31-71-527-4603
j.matysik@chem.leidenuniv.nl
www.cidnp.net
****************************************************
Biophysical Techniques in Photosynthesis, Vol. 2
T.J. Aartsma & J. Matysik, eds. (2008)
http://www.springer.com/978-1-4020-8249-8
****************************************************

STOCKMAN POSDOCTORAL RESEARCH FELLOWSHIP

STOCKMAN POSDOCTORAL RESEARCH FELLOWSHIP IN CHEMISTRY FOR THE ARTS

With support from the Stockman Family Foundation, Pratt Institute is offering a one-year post doctoral fellowship in Chemistry applied to the study of works of art. The fellowship includes an annual stipend and allowances for research related travel. The stipend is commensurate with the candidate's education and experience. The fellow will work in the department of Mathematic and Science, Chemistry for the Arts Laboratory. The laboratory is developing and optimizing unilateral Nuclear Magnetic Resonance techniques to address questions involving the degradation processes of works of art. This work is being done in collaboration with researchers at academic institutions and other research laboratories.

The successful candidate should hold a Ph.D, in Chemistry, Physics or Conservation Science. Knowledge of NMR techniques and a strong interest in art conservation science is a plus. English-language skills and a proven record of research and writing ability are required. Fellowships are awarded without regard to age, sex, nationality, or race. Finalists who are not United States citizens must provide proof of their own health insurance coverage before starting the position.

APPLICATION PROCEDURE
Interested candidates must submit the following materials
1. A curriculum vitae including basic biographical information, current and permanent addresses, and telephone numbers
2. A short statement of the candidate's interests and intent in applying for the fellowship
3. Reprints of publications
4. Two letters of recommendation from professionals familiar with the candidate's work and one letter of personal reference

All application materials, including letters of recommendation should be received no later than February 1st, 2009 and should be submitted via email toedelfede@pratt.edu and regular mail to

Eleonora Del Federico
Department of Mathematics and Science
Pratt Institute
200 Willoughby Ave
Brooklyn, NY 11205

Donnerstag, 4. Dezember 2008

Post Doctoral Fellow NMR Engineering

Post Doctoral Fellow NMR Engineering
School of Engineering & Computer Science, Victoria University of Wellington, New Zealand
An exciting opportunity exists for a physicist or electronics engineer to join a research group working on novel Nuclear Magnetic Resonance technologies, a project funded by the New Zealand Foundation for Research Science and Technology.
The position of Post Doctoral Fellow is in the School of Engineering and will involve the development of new NMR electronic hardware, software, techniques and applications. Preference will be given to candidates who have previous experience in working on NMR instrumentation technologies.



For more information go to: http://vacancies.vuw.ac.nz/positiondetail.asp?p=4630

Montag, 1. Dezember 2008

Open position in Varian SA

VARIAN SA, the French subsidiary of Varian Inc., is looking for an
Application and Product Specialist, NUCLEAR MAGNETIC RESONANCE,
Belgium and France with responsibility for supporting the commercial team and providing applications support to the core market sectors; universities, pharmaceutical clients, hospitals, etc.

The ideal candidate would be qualified in a scientific discipline, with a good working knowledge of NMR and a positive commercial attitude. This person will be required to work autonomously, using their own initiative and to have a great deal of motivation, an enthusiastic approach to work and for the projects entrusted to them.
A high level of English is required in order to participate in training programmes within Europe and the US.
Availability to travel is essential.

We offer an attractive package as a market leader in our sector. A rewarding package is available to the right candidate, including a company car, private medical insurance, pension plan and other advantages.
Interested candidates to forward a CV in the first instance by e-mail to fr.personnel@varianinc.com