We are looking for suitable candidates for a post-doctoral position in our team at the Ecole Normale Superieure, Paris, with the support of the Agence Nationale de la Recherche (ANR). The main thrust would be solid-state NMR of microcrystalline proteins that are relevant to DNA repair (in collaboration with the Institut Curie in Paris), possibly in combination with DNP using a gyrotron at the Ecole Polytechnique Federale in Lausanne. The position is initially available for two years, preferably starting before October 2010.
Prof. Geoffrey Bodenhausen
Département de chimie,
Ecole Normale Supérieure
24 rue Lhomond,
75231 Paris cedex 05, France
0033 1 44 32 33 89
http://www.chimie.ens.fr/Resonance
Dienstag, 11. Mai 2010
PhD Position in Wellington - New Zealand
The MacDiarmid Institute for Advanced Materials and Nanotechnology at
the Victoria University of Wellington (Wellington / New Zealand) is
offering a PhD position, available from October 2010.
The research will be in the field of soft matter (complex fluids
investigated by means of Rheo-NMR under high shear rates, application
of multidimensional NMR methods) and porous materials (NMR velocimetry
and diffusometry on fluids in complex pore systems, application of
multidimensional Inverse Laplace techniques and high pulsed field
gradients). The research to be undertaken concerns addressing
fundamental questions related to soft matter and porous media as well
as the development of the necessary NMR methodology.
We seek applications from national and international students who have
graduated in physics or chemistry, preferably with a background in
NMR. The successful applicant will be given the opportunity to work
in a well recognised NMR group (http://www.macdiarmid.ac.nz/nmr/) with
strong national and international collaborations. The PhD position is
fully funded (including fees) and enables one to stay in a well
established academic (http://www.victoria.ac.nz/scps/index.aspx) as
well as urban environment (http://www.wellingtonnz.com/).
Please send your application (including the email addresses of two
referees) together with a recent CV by email to
petrik.galvosas@vuw.ac.nz.
the Victoria University of Wellington (Wellington / New Zealand) is
offering a PhD position, available from October 2010.
The research will be in the field of soft matter (complex fluids
investigated by means of Rheo-NMR under high shear rates, application
of multidimensional NMR methods) and porous materials (NMR velocimetry
and diffusometry on fluids in complex pore systems, application of
multidimensional Inverse Laplace techniques and high pulsed field
gradients). The research to be undertaken concerns addressing
fundamental questions related to soft matter and porous media as well
as the development of the necessary NMR methodology.
We seek applications from national and international students who have
graduated in physics or chemistry, preferably with a background in
NMR. The successful applicant will be given the opportunity to work
in a well recognised NMR group (http://www.macdiarmid.ac.nz/nmr/) with
strong national and international collaborations. The PhD position is
fully funded (including fees) and enables one to stay in a well
established academic (http://www.victoria.ac.nz/scps/index.aspx) as
well as urban environment (http://www.wellingtonnz.com/).
Please send your application (including the email addresses of two
referees) together with a recent CV by email to
petrik.galvosas@vuw.ac.nz.
POSTDOCTORAL/RESEARCH SCIENTIST POSITIONS MRI
POSTDOCTORAL/RESEARCH SCIENTIST POSITIONS IN
MULTINUCLEAR MUSCULOSKELETAL NMR/MRI
DESCRIPTION:
We are seeking highly motivated candidates for an NIH-funded post-doctoral/Asst. Research
scientist positions in multinuclear musculoskeletal MRI research in the Radiology Department
of New York University Langone Medical Center. The candidate will join the exiting and
expanding Musculoskeletal Imaging Group in the Department of Radiology and the Chemistry
Department. The imaging group consists of 11 MSK radiologists. The candidate should have
an excellent background in the application of NMR/MRI to biological models and
understanding of the concepts of NMR physics and experimental NMR techniques.
Experience in musculoskeletal MRI (cartilage/trabecular bone/skeletal muscle) applications is
an advantage. The candidate will also have access to interact with the other researchers in
the center for biomedical imaging and department of Chemistry who have number of ongoing
projects related to arthritis. We are looking for motivated persons with experience in MRI to
assist in this research program. There are opportunities to work closely with a dedicated
musculoskeletal imaging basic scientists as well as a large group of diverse MR physicists,
chemists and RF engineers.
FACILITY:
Our research facility includes several thousand square feet of dedicated research space, three
state -of -the-art Siemens 3T Trio MR scanners and a 7T whole body MR with 8 channel
parallel transmit system dedicated to research, as well as seven Siemens scanners used for
clinical research, and a dedicated cartilage laboratory. A small bore system (9.4T) is also
available at Department Chemistry for spectroscopy applications. The orthopedic and
Rheumatology departments are among the largest and busiest in the country. The
musculoskeletal MRI program is currently undergoing rapid expansion.
QUALIFICATIONS:
Applicants must have an advanced degree (Ph.D) in Physical Science, Electrical, Biomedical
Engineering or related field. The candidate must be familiar with computer operating systems
and programming languages, particularly MatLab, C++, etc. Remuneration is competitive and
commensurate with experience and will be based on New York University guidelines, Women
and Minorities are encouraged to apply.
CONTACT:
Please forward your C.V. including a list of your publications, and the names/addresses of 3
references to:
Ravinder Regatte, PhD
Department of Radiology
NYU Langone Medical Center
New York, NY 10016.
Ph. (212) 263-4857
E-mail: ravinder.regatte@nyumc.org
OR
Alexej Jerschow Ph.D.
Department of Chemistry
New York University
New York, NY 10003.
E-mail: alexej.jerschow@nyu.edu
MULTINUCLEAR MUSCULOSKELETAL NMR/MRI
DESCRIPTION:
We are seeking highly motivated candidates for an NIH-funded post-doctoral/Asst. Research
scientist positions in multinuclear musculoskeletal MRI research in the Radiology Department
of New York University Langone Medical Center. The candidate will join the exiting and
expanding Musculoskeletal Imaging Group in the Department of Radiology and the Chemistry
Department. The imaging group consists of 11 MSK radiologists. The candidate should have
an excellent background in the application of NMR/MRI to biological models and
understanding of the concepts of NMR physics and experimental NMR techniques.
Experience in musculoskeletal MRI (cartilage/trabecular bone/skeletal muscle) applications is
an advantage. The candidate will also have access to interact with the other researchers in
the center for biomedical imaging and department of Chemistry who have number of ongoing
projects related to arthritis. We are looking for motivated persons with experience in MRI to
assist in this research program. There are opportunities to work closely with a dedicated
musculoskeletal imaging basic scientists as well as a large group of diverse MR physicists,
chemists and RF engineers.
FACILITY:
Our research facility includes several thousand square feet of dedicated research space, three
state -of -the-art Siemens 3T Trio MR scanners and a 7T whole body MR with 8 channel
parallel transmit system dedicated to research, as well as seven Siemens scanners used for
clinical research, and a dedicated cartilage laboratory. A small bore system (9.4T) is also
available at Department Chemistry for spectroscopy applications. The orthopedic and
Rheumatology departments are among the largest and busiest in the country. The
musculoskeletal MRI program is currently undergoing rapid expansion.
QUALIFICATIONS:
Applicants must have an advanced degree (Ph.D) in Physical Science, Electrical, Biomedical
Engineering or related field. The candidate must be familiar with computer operating systems
and programming languages, particularly MatLab, C++, etc. Remuneration is competitive and
commensurate with experience and will be based on New York University guidelines, Women
and Minorities are encouraged to apply.
CONTACT:
Please forward your C.V. including a list of your publications, and the names/addresses of 3
references to:
Ravinder Regatte, PhD
Department of Radiology
NYU Langone Medical Center
New York, NY 10016.
Ph. (212) 263-4857
E-mail: ravinder.regatte@nyumc.org
OR
Alexej Jerschow Ph.D.
Department of Chemistry
New York University
New York, NY 10003.
E-mail: alexej.jerschow@nyu.edu
Donnerstag, 29. April 2010
Scientist (Postdoc) with NMR and HPLC experience
Department of Pharmaceutical Biotechnology at Universität des Saarlandes, Saarbrücken:
Scientist (Postdoc) with NMR and HPLC experience
Description of the position: Using the NMR infrastructure available at Saarland University (Bruker 700 MHz NMR equipped with Cryoprobe and LC-coupling), your new job includes establishing LC-NMR methods aimed at the structural elucidation of natural products. You are about to join a multidisciplinary team with colleagues trained in chemistry, pharmacy, biology or biotechnology, contributing your skills to numerous projects. It is the primary objective of your research to conduct the de novo structure elucidation of newly discovered, complex bacterial secondary metabolites which are frequently available in low yields only. Your expert knowledge enables you to actively pursue the development and optimisation of analytical methods for that purpose.
Requirements: Degree in chemistry or pharmacy with completed PhD, ideally with an analytical focus (NMR, HPLC, MS).
Additional specifications: Besides a profound knowledge of NMR spectroscopy, liquid chromatography and mass spectrometry, the successful applicant has prior experience with the separation of complex metabolite mixtures. Furthermore, he/she has experience with studies of biosynthetic pathways and basic knowledge about feeding experiments with producers of natural products. Ideally, successful research activity since PhD completion is well-documented by publications. Fluency in scientific English, both spoken and written is essential, German language skills are appreciated but not required.
Please visit the University website for further details and refer to position "W246" when sending your application to: Prof. Dr. Rolf Müller, Pharmazeutische Biotechnologie, Campus C2 3, Postfach 15 11 50, 66041 Saarbrücken.
Link to pdf File: http://www.uni-saarland.de/fileadmin/user_upload/extranet_uds/campus/service/Stellenausschreibung/Wissenschaftliches_Personal/W246.pdf
Scientist (Postdoc) with NMR and HPLC experience
Description of the position: Using the NMR infrastructure available at Saarland University (Bruker 700 MHz NMR equipped with Cryoprobe and LC-coupling), your new job includes establishing LC-NMR methods aimed at the structural elucidation of natural products. You are about to join a multidisciplinary team with colleagues trained in chemistry, pharmacy, biology or biotechnology, contributing your skills to numerous projects. It is the primary objective of your research to conduct the de novo structure elucidation of newly discovered, complex bacterial secondary metabolites which are frequently available in low yields only. Your expert knowledge enables you to actively pursue the development and optimisation of analytical methods for that purpose.
Requirements: Degree in chemistry or pharmacy with completed PhD, ideally with an analytical focus (NMR, HPLC, MS).
Additional specifications: Besides a profound knowledge of NMR spectroscopy, liquid chromatography and mass spectrometry, the successful applicant has prior experience with the separation of complex metabolite mixtures. Furthermore, he/she has experience with studies of biosynthetic pathways and basic knowledge about feeding experiments with producers of natural products. Ideally, successful research activity since PhD completion is well-documented by publications. Fluency in scientific English, both spoken and written is essential, German language skills are appreciated but not required.
Please visit the University website for further details and refer to position "W246" when sending your application to: Prof. Dr. Rolf Müller, Pharmazeutische Biotechnologie, Campus C2 3, Postfach 15 11 50, 66041 Saarbrücken.
Link to pdf File: http://www.uni-saarland.de/fileadmin/user_upload/extranet_uds/campus/service/Stellenausschreibung/Wissenschaftliches_Personal/W246.pdf
Donnerstag, 22. April 2010
Scientist – NMR Spectroscopist Genentech San Francisco
Scientist – NMR Spectroscopist
RESPONSIBILITIES:
We have an opportunity for a highly talented and motivated NMR spectroscopist to join
the Protein NMR Group at Genentech. The primary responsibilities of this position will be to help develop, lead, and implement NMR-based strategies to support small molecule drug discovery programs, working closely with the Biochemical Pharmacology
and Discovery Chemistry Departments, and participating directly with small molecule project teams to aid the design of new small molecule compounds.
Job responsibilities include protein sample preparation, protein characterization, hands-on NMR data acquisition and analysis, focused on assessing ligand-binding and analyzing the solution structures of proteins or protein/ligand complexes involved in modulating cell-signaling events of therapeutic interest. The protein NMR facility includes dedicated 800, 600, and 500 MHz spectrometers, Linux workstations, and access to the Central California 900 MHz spectrometer. Our NMR group complements protein expression, purification and crystallography efforts within the Structural
Biology Department.
REQUIREMENTS:
The successful candidate will have a Ph.D and postdoctoral training in chemistry,
biochemistry or a related biophysics field, with a minimum of five years of technical
experience in areas related to protein NMR, protein biochemistry, and/or NMR in a drug discovery environment. The successful candidate will show evidence of productive, independent contributions in science, as demonstrated by a strong publication record. Knowledge and hands-on expertise in protein expression, purification, NMR sample preparation, and protein NMR spectroscopy is required; experience using automation would be a plus. He/she must also be an excellent problem-solver, have a strong work ethic, and be capable of working independently within a collaborative team setting. Strong analytical, communication, and organizational skills also required.
Genentech is dedicated to fostering an environment that is inclusive and encourages
diversity of thought, style, skills and perspective.
To learn more about our current opportunities, please visit: http://careers.gene.com
and reference Req. #1000031194.
Please use “gene” when a source is requested.
Genentech is an equal opportunity employer.
RESPONSIBILITIES:
We have an opportunity for a highly talented and motivated NMR spectroscopist to join
the Protein NMR Group at Genentech. The primary responsibilities of this position will be to help develop, lead, and implement NMR-based strategies to support small molecule drug discovery programs, working closely with the Biochemical Pharmacology
and Discovery Chemistry Departments, and participating directly with small molecule project teams to aid the design of new small molecule compounds.
Job responsibilities include protein sample preparation, protein characterization, hands-on NMR data acquisition and analysis, focused on assessing ligand-binding and analyzing the solution structures of proteins or protein/ligand complexes involved in modulating cell-signaling events of therapeutic interest. The protein NMR facility includes dedicated 800, 600, and 500 MHz spectrometers, Linux workstations, and access to the Central California 900 MHz spectrometer. Our NMR group complements protein expression, purification and crystallography efforts within the Structural
Biology Department.
REQUIREMENTS:
The successful candidate will have a Ph.D and postdoctoral training in chemistry,
biochemistry or a related biophysics field, with a minimum of five years of technical
experience in areas related to protein NMR, protein biochemistry, and/or NMR in a drug discovery environment. The successful candidate will show evidence of productive, independent contributions in science, as demonstrated by a strong publication record. Knowledge and hands-on expertise in protein expression, purification, NMR sample preparation, and protein NMR spectroscopy is required; experience using automation would be a plus. He/she must also be an excellent problem-solver, have a strong work ethic, and be capable of working independently within a collaborative team setting. Strong analytical, communication, and organizational skills also required.
Genentech is dedicated to fostering an environment that is inclusive and encourages
diversity of thought, style, skills and perspective.
To learn more about our current opportunities, please visit: http://careers.gene.com
and reference Req. #1000031194.
Please use “gene” when a source is requested.
Genentech is an equal opportunity employer.
Group leader position in NMR at Institut Curie
Group leader position in NMR at Institut Curie
Institut Curie, a leading biomedical research institute devoted to the understanding of normal and cancerous cells, is looking for a junior/senior group leader to join the “Integrative imaging: from molecules to organisms” Department (Institut Curie – INSERM U759). The candidate is expected to perform an independent and high quality research program to develop and apply recent NMR spectroscopy approaches including the study of non-ordered protein domains and in-cell NMR. He (she) is expected to establish collaborations with groups working on proteins complexes which form part of centrosomes or which are related with the microtubular system.
Application deadline is July 14th 2010.
Applicants should include a brief description of research accomplishments and future research plans (less than 5 pages in total), CV and names and addresses of three references to:
Dr. Sergio Marco
Institut Curie
Bat 112, Centre Universitaire
91405 Orsay, France
email : sergio.marco@curie.fr
Information about the Research Center and the Hospital are available on our website : www.curie.fr
Institut Curie, a leading biomedical research institute devoted to the understanding of normal and cancerous cells, is looking for a junior/senior group leader to join the “Integrative imaging: from molecules to organisms” Department (Institut Curie – INSERM U759). The candidate is expected to perform an independent and high quality research program to develop and apply recent NMR spectroscopy approaches including the study of non-ordered protein domains and in-cell NMR. He (she) is expected to establish collaborations with groups working on proteins complexes which form part of centrosomes or which are related with the microtubular system.
Application deadline is July 14th 2010.
Applicants should include a brief description of research accomplishments and future research plans (less than 5 pages in total), CV and names and addresses of three references to:
Dr. Sergio Marco
Institut Curie
Bat 112, Centre Universitaire
91405 Orsay, France
email : sergio.marco@curie.fr
Information about the Research Center and the Hospital are available on our website : www.curie.fr
Post-doctoral position in membrane protein structural biology Biozentrum Basel
A postdoctoral position is available in the group of Sebastian Hiller at the Biozentrum of the University Basel, starting August 1, 2010. We are studying the structure and function of integral membrane proteins and their complexes with NMR. Our projects address fundamental biological processes of high impact. A representative example for our research is the human voltage-dependent anion channel (VDAC) (1,2).
The postdoctoral research project concerns the de novo structure determination of a membrane protein complex involved in substrate transport across membranes. We will establish the sample preparation using native-like membrane mimics and determine the structure to atomic resolution using solution and solid-state NMR. Subsequently, the functioning of the protein complex and its interactions with ligands are characterized. An integral part of our projects is the use and development of state-of-the-art biochemical and NMR techniques (3).
Interested candidates need a Ph.D. in Biochemistry, Biophysics, Structural or Molecular Biology or related fields. Expertise in at least one of the following areas is mandatory: NMR, protein biochemistry, membrane proteins, molecular biology. The successful candidate is highly motivated, creative and capable of contributing productively in a team environment. Communication skills in oral and written English are essential.
The position and the research projects are long-term funded by the Swiss National Science Foundation (SNSF). We offer an exciting and enthusiastic work environment with scientific collaborations in the institute and worldwide. The Biozentrum Basel is one of the leading biomedical research institutions in Switzerland and has recently been placed among the Top 10 international “Best Places to Work for Postdocs” by The Scientist magazine. Facilities for structural biology include 600 MHz and 800 MHz Bruker spectrometers equipped with cryogenic and magic angle spinning probes. Salary and benefits are attractive, following the guidelines of the Swiss National Science Foundation. The start date is August 1, 2010 or on mutual agreement.
Applications and informal queries about the lab and research projects should be directed by email to Sebastian Hiller. Applications should include a cover letter summarizing current and future research interests, a CV, list of publications and contact information for at least two references.
Prof. Sebastian Hiller
Biozentrum, University of Basel
Klingelbergstrasse 50/70
4056 Basel, Switzerland
http://www.biozentrum.unibas.ch/hiller/
Email: sebastian.hiller@unibas.ch
Phone: +41 44 633 43 45
Fax: +41 44 632 16 21
References
1. Hiller S, Garces RG, Malia TJ, Orekhov VY, Colombini M and Wagner G. Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science 321, 1206–1210 (2008).
2. Raschle T, Hiller S, Yu TY, Rice AJ, Walz T and Wagner G. Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs. J. Am. Chem. Soc. 131, 17777–17779 (2009).
3. Hiller S, Ibraghimov I, Wagner G and Orekhov VY. Coupled decomposition of four-dimensional NOESY spectra. J. Am. Chem. Soc. 131, 12970–12978 (2009).
The postdoctoral research project concerns the de novo structure determination of a membrane protein complex involved in substrate transport across membranes. We will establish the sample preparation using native-like membrane mimics and determine the structure to atomic resolution using solution and solid-state NMR. Subsequently, the functioning of the protein complex and its interactions with ligands are characterized. An integral part of our projects is the use and development of state-of-the-art biochemical and NMR techniques (3).
Interested candidates need a Ph.D. in Biochemistry, Biophysics, Structural or Molecular Biology or related fields. Expertise in at least one of the following areas is mandatory: NMR, protein biochemistry, membrane proteins, molecular biology. The successful candidate is highly motivated, creative and capable of contributing productively in a team environment. Communication skills in oral and written English are essential.
The position and the research projects are long-term funded by the Swiss National Science Foundation (SNSF). We offer an exciting and enthusiastic work environment with scientific collaborations in the institute and worldwide. The Biozentrum Basel is one of the leading biomedical research institutions in Switzerland and has recently been placed among the Top 10 international “Best Places to Work for Postdocs” by The Scientist magazine. Facilities for structural biology include 600 MHz and 800 MHz Bruker spectrometers equipped with cryogenic and magic angle spinning probes. Salary and benefits are attractive, following the guidelines of the Swiss National Science Foundation. The start date is August 1, 2010 or on mutual agreement.
Applications and informal queries about the lab and research projects should be directed by email to Sebastian Hiller. Applications should include a cover letter summarizing current and future research interests, a CV, list of publications and contact information for at least two references.
Prof. Sebastian Hiller
Biozentrum, University of Basel
Klingelbergstrasse 50/70
4056 Basel, Switzerland
http://www.biozentrum.unibas.ch/hiller/
Email: sebastian.hiller@unibas.ch
Phone: +41 44 633 43 45
Fax: +41 44 632 16 21
References
1. Hiller S, Garces RG, Malia TJ, Orekhov VY, Colombini M and Wagner G. Solution structure of the integral human membrane protein VDAC-1 in detergent micelles. Science 321, 1206–1210 (2008).
2. Raschle T, Hiller S, Yu TY, Rice AJ, Walz T and Wagner G. Structural and functional characterization of the integral membrane protein VDAC-1 in lipid bilayer nanodiscs. J. Am. Chem. Soc. 131, 17777–17779 (2009).
3. Hiller S, Ibraghimov I, Wagner G and Orekhov VY. Coupled decomposition of four-dimensional NOESY spectra. J. Am. Chem. Soc. 131, 12970–12978 (2009).
Donnerstag, 15. April 2010
Post-doctoral position
The laboratory of Prof. Dominique Frueh in the department of Biophysics at Johns Hopkins School of Medicine offers Post-doctoral positions to investigate dynamic modular enzymatic systems related to antibiotics biosynthesis. While we use a multidisciplinary approach, Nuclear Magnetic Resonance (NMR) is our primary technique. We seek candidates with a high expertise in protein production and purification and with an interest in learning advanced biomolecular NMR techniques. The post-doctorant will benefit from our strong expertise in NMR (both applied and theoretical) and from a comfortable setup at Johns Hopkins University (800 MHz, four 600 MHz, two 500 MHz and current expansion in progress). In addition, the laboratory has access to new state-of-the-art wetlab equipment and benefits from the collegial and dynamic framework of the Johns Hopkins Medical Institute. No prior knowledge of NMR is required but a strong motivation to learn the technique is necessary and complete independence in the wetlab is expected. http://biophysics.med.jhmi.edu/BIOPHYS/frueh.html
Outstanding benefits are offered and international candidates are welcomed (see note below) http://www.hopkinsmedicine.org/jhpda/
See also http://baltimore.org/
Interested candidates should submit a CV and a cover letter as well as two letters of references (or contact information) to:
dfrueh1@jhmi.edu.
Applications from all countries will be considered but applicants that can arrange for an interview (in one form or another) will be preferred.
Outstanding benefits are offered and international candidates are welcomed (see note below) http://www.hopkinsmedicine.org/jhpda/
See also http://baltimore.org/
Interested candidates should submit a CV and a cover letter as well as two letters of references (or contact information) to:
dfrueh1@jhmi.edu.
Applications from all countries will be considered but applicants that can arrange for an interview (in one form or another) will be preferred.
Research Assistant / Associate
Research Assistant / Associate in NMR Spectroscopy
The University of Manchester - School of Chemistry
Closing date: 27/04/2010
Reference: EPS/10204
Applications are invited for an EPSRC Research Associate to work with Dr
Mathias Nilsson and Professor Gareth Morris on the development of
techniques in diffusion-ordered NMR spectroscopy (DOSY). The project
will combine high quality NMR measurements using world-class facilities
in the School of Chemistry, theoretical analysis, pulse sequence
development, and multivariate analysis, and offers an excellent
opportunity for a suitable candidate to build a wide NMR skill set.The
successful candidate will implement, analyse, evaluate and apply a range
of new NMR experiments in the field of matrix-assisted DOSY, working
closely with Dr. Nilsson, Prof. Morris and other members of the research
group. Equipment available includes Bruker and Varian spectrometers at
300, 400, 500 MHz field strengths.The appointee will have, or be about
to obtain, a doctoral degree in a relevant subject (e.g. Chemistry,
Physics, Engineering, Computer Science). They should possess good
written and oral communication skills, the ability to function
efficiently as part of a team, and experience in and understanding of
some or all of:
* NMR methods, especially DOSY and others involving pulsed field
gradients
* Software for NMR data processing
* NMR spectrometer hardware
* Surface chemistry/chemical interactions
* Unix and C programming
* Mathematica and Matlab programming
The position is available from 1 May 2010 for up to 36 months.
Salary
£28,983 - £35,646 p.a.
Further particulars:
http://www.jobs.ac.uk/job/AAX364/research-assistant-associate-in-nmr-spectroscopy/
Informal enquiries
Dr. Mathias Nilsson.
Tel: + 44 (0) 161 306 4465
Email: mathias.nilsson@manchester.ac.uk
Or
Professor Gareth Morris
Tel: + 44 (0) 161 275 4665
Email: gareth.morris@manchester.ac.uk
The University of Manchester - School of Chemistry
Closing date: 27/04/2010
Reference: EPS/10204
Applications are invited for an EPSRC Research Associate to work with Dr
Mathias Nilsson and Professor Gareth Morris on the development of
techniques in diffusion-ordered NMR spectroscopy (DOSY). The project
will combine high quality NMR measurements using world-class facilities
in the School of Chemistry, theoretical analysis, pulse sequence
development, and multivariate analysis, and offers an excellent
opportunity for a suitable candidate to build a wide NMR skill set.The
successful candidate will implement, analyse, evaluate and apply a range
of new NMR experiments in the field of matrix-assisted DOSY, working
closely with Dr. Nilsson, Prof. Morris and other members of the research
group. Equipment available includes Bruker and Varian spectrometers at
300, 400, 500 MHz field strengths.The appointee will have, or be about
to obtain, a doctoral degree in a relevant subject (e.g. Chemistry,
Physics, Engineering, Computer Science). They should possess good
written and oral communication skills, the ability to function
efficiently as part of a team, and experience in and understanding of
some or all of:
* NMR methods, especially DOSY and others involving pulsed field
gradients
* Software for NMR data processing
* NMR spectrometer hardware
* Surface chemistry/chemical interactions
* Unix and C programming
* Mathematica and Matlab programming
The position is available from 1 May 2010 for up to 36 months.
Salary
£28,983 - £35,646 p.a.
Further particulars:
http://www.jobs.ac.uk/job/AAX364/research-assistant-associate-in-nmr-spectroscopy/
Informal enquiries
Dr. Mathias Nilsson.
Tel: + 44 (0) 161 306 4465
Email: mathias.nilsson@manchester.ac.uk
Or
Professor Gareth Morris
Tel: + 44 (0) 161 275 4665
Email: gareth.morris@manchester.ac.uk
CALL FOR PHD CANDIDATES
CALL FOR PHD CANDIDATES
The CEISAM laboratory (UMR 6230, CNRS-University of Nantes), located in Nantes, France, is recruiting a highly motivated student for a 3-years PhD position. Subject: "Methodological developments in ultrafast 2D NMR for metabolic studies". Financial support from the French Ministry of Research or from the French National Research Agency (ANR) is expected.
2D NMR is a powerful analytical tool, widely used in chemistry, biochemistry or for biomedical applications. However, its use for quantitative studies is limited by long acquisition durations that characterize this methodology. A so-called “ultrafast” methodology was recently proposed1 to record a full 2D spectrum in a single scan and in a fraction of a second. Our group is one of the world’s leading teams for developing this novel and promising methodology. We have recently shown that it could be used for quantitative purposes with an excellent precision2 . However, further development is necessary to make it suitable for studying complex metabolic mixtures.
The recruited candidate will develop ultrafast 2D NMR methods to improve their performances for studying complex samples. The methodology will be evaluated for a variety of applications such as chemical or microbiological kinetic studies, and metabolic applications. The student will be encouraged to present his/her results in national and international conferences.
Prospective PhD candidates must hold a Master degree in Physical Chemistry, Chemical Physics or Analytical Chemistry and have solid knowledge in NMR. A previous experience in experimental NMR and/or programming will be a plus. The candidates should be highly motivated and show an aptitude to work independently.
Contact
Patrick Giraudeau (patrick.giraudeau@univ-nantes.fr)
Serge Akoka (serge.akoka@univ-nantes.fr)
CEISAM, Bât. 9, Faculté des Sciences et des Techniques – BP 92208
2 rue de la Houssinière 44322 Nantes Cedex 3
FRANCE
Tel : 02.51.12.57.07 / 02.51.12.57.09
Références :
1. L. Frydman, T. Scherf, A. Lupulescu, Prod. Natl. Acad. Sci. USA 99 (2002) 15858-15862.
2. P. Giraudeau, G.S. Remaud, S. Akoka, Anal. Chem. 81 (2009) 479-484.
The CEISAM laboratory (UMR 6230, CNRS-University of Nantes), located in Nantes, France, is recruiting a highly motivated student for a 3-years PhD position. Subject: "Methodological developments in ultrafast 2D NMR for metabolic studies". Financial support from the French Ministry of Research or from the French National Research Agency (ANR) is expected.
2D NMR is a powerful analytical tool, widely used in chemistry, biochemistry or for biomedical applications. However, its use for quantitative studies is limited by long acquisition durations that characterize this methodology. A so-called “ultrafast” methodology was recently proposed1 to record a full 2D spectrum in a single scan and in a fraction of a second. Our group is one of the world’s leading teams for developing this novel and promising methodology. We have recently shown that it could be used for quantitative purposes with an excellent precision2 . However, further development is necessary to make it suitable for studying complex metabolic mixtures.
The recruited candidate will develop ultrafast 2D NMR methods to improve their performances for studying complex samples. The methodology will be evaluated for a variety of applications such as chemical or microbiological kinetic studies, and metabolic applications. The student will be encouraged to present his/her results in national and international conferences.
Prospective PhD candidates must hold a Master degree in Physical Chemistry, Chemical Physics or Analytical Chemistry and have solid knowledge in NMR. A previous experience in experimental NMR and/or programming will be a plus. The candidates should be highly motivated and show an aptitude to work independently.
Contact
Patrick Giraudeau (patrick.giraudeau@univ-nantes.fr)
Serge Akoka (serge.akoka@univ-nantes.fr)
CEISAM, Bât. 9, Faculté des Sciences et des Techniques – BP 92208
2 rue de la Houssinière 44322 Nantes Cedex 3
FRANCE
Tel : 02.51.12.57.07 / 02.51.12.57.09
Références :
1. L. Frydman, T. Scherf, A. Lupulescu, Prod. Natl. Acad. Sci. USA 99 (2002) 15858-15862.
2. P. Giraudeau, G.S. Remaud, S. Akoka, Anal. Chem. 81 (2009) 479-484.
Abonnieren
Posts (Atom)