Freitag, 25. Januar 2008

Postdoctoral Fellow - in vivo MRI - New York

The Bone Cell Biology and Imaging Laboratory at the Hospital for Special Surgery together with the In Vivo Nuclear Magnetic Resonance Laboratory at Memorial Sloan-Kettering Cancer Center is seeking a postdoctoral fellow interested in leading the development of in vivo magnetic resonance imaging of bone cell activity. Candidates should have a strong background in magnetic resonance research as well as an interest in biology and translational research.

The Hospital for Special Surgery (www.hss.edu) and Memorial Sloan-Kettering Cancer Center (www.mskcc.org) are among the leading research institutions in the world and are located within the same campus in Manhattan, New York. Please direct inquiries to Dr. Philipp Mayer-Kuckuk at mayerkuckukp@hss.edu.

Mittwoch, 23. Januar 2008

A 6 month position in Reims, France

A six month position is available in my group in Reims, France,
for a *non-French* visiting Professor or an Assistant Professor or
any holder of an equivalent *permanent* academic position.
It is open starting from now and will remain open until the end of 2008.
The position is funded by the CNRS, the French
National Concil for Scientific Research.
The research project deals with the application
of selective pulses for the NMR spectral assignment
of complex molecules in solution, mainly oligosaccharides.
Please send me a detailed CV is you want to apply.

Contact: jm.nuzillard@univ-reims.fr
NMR Web site: www.univ-reims.fr/LSD/JmnSoft
Publications: www.univ-reims.fr/Labos/FRE2715/publications-JMN.pdf
CV: www.univ-reims.fr/Labos/FRE2715/CV-JMN-en.pdf

Donnerstag, 17. Januar 2008

Postdoc in solid-state NMR of pharmaceuticals at Durham (UK)

As a result of the imminent departure of the current position holder for a permanent position, the Durham Solid-State NMR group expects a postdoctoral vacancy of about 12 months (depending on appointment level) to be available from April.

The project ("Elucidating structure and dynamics in pharmaceutical solvates") essentially is show-casing the power of modern solid-state NMR to obtained detailed information about local structure and dynamics in complex materials of technological importance, and connects with innovative work in the group using molecular dynamics to relate molecular-level detail to bulk properties. A set of interesting systems (both from the NMR and applications viewpoint) has already been identified in the initial phase of the project. Since the systems are now familiar, the project is quite suitable for newly-qualified spectroscopists wishing to gain further experience in solid-state NMR, contacts with the pharmaceutical industry, and with specialist DFT-based code for calculating NMR parameters in solids (CASTEP).
But the project also offers opportunities for more experienced researchers to devise novel techniques for the characterisation of locally dynamic materials.

More information on the Solid-State NMR group in Durham can be found on our web pages (link below). Potential applicants are encouraged to contact me as soon as possible for more information about this position (or life in the historic cathedral city of Durham) so that we can make a rapid appointment when the position formally becomes available.

Paul Hodgkinson

E: paul.hodgkinson@durham.ac.uk
T: +44 191 334 2019
W: http://www.dur.ac.uk/paul.hodgkinson

Dienstag, 18. Dezember 2007

Post Doc Strasbourg (France)

A two years post-doctoral position is available in the group of biomolecular NMR of IGBMC in Strasbourg (France) to work on the interactions between the HPV oncoprotein E6 and molecular partners involved in oncogenesis. The main investigation tools will be solution NMR in combination with complementary biophysical technics such as X-ray crystallography or biacore. More details may be found in Mol Cell. 2006 21:665-78. The project offers many opportunities to develop innovative approaches to study protein-protein interactions such as novel isotope labelling schemes.

This position is intended to young researchers having an experience in protein NMR spectroscopy (expression and purification, triple resonance, structure determination). Additional experience in molecular cloning will be also valuable but not necessary. The position is available immediately.

Our lab is equipped with one 600 Bruker Avance NMR spectrometer with cryoprobe, cloning platform and protein expression facilities.

Applicants are invited to send a curriculum vitae and a brief statement of research along with letters of reference to:

____________________________________________________________________

Bruno KIEFFER


IGBMC Biomolecular NMR group, CNRS UMR 7104


ECOLE SUPERIEURE DE BIOTECHNOLOGIE DE STRASBOURG

Boulevard Sebastien Brant BP10413

F-67412 ILLKIRCH Cedex FRANCE


Fax : (33) 03.90.24.47.18

Voice : (33) 03.90.24.47.22

web : http://www-igbmc.u-strasbg.fr/recherche/Dep_BGS/Eq_BruKief/

Post-doc in computational biomolecular NMR

Description of the Faculty / Research group
----------------------------------------------------------
The new Faculty of Science consists of six departments: Biology, Pharmaceutical Sciences, Information and Computing Sciences, Physics and Astronomy, Mathematics and Chemistry. The Faculty is home to 3500 students and nearly 2000 staff and is internationally renowned for the quality of its research.

The NMR Research Group (http://www.nmr.chem.uu.nl), headed by Prof. R. Boelens, is part of the Chemistry Department (http://www.chem.uu.nl) and belongs to the Bijvoet Center for Biomolecular Research (http://www.bijvoet-center.nl). The research within the NMR group is focused on the structure determination of proteins and protein complexes by high-resolution NMR spectroscopy and bio-computational modelling. The group has strong research lines on protein-DNA and protein-protein complexes in transcription and DNA repair and modelling of bio-molecular complexes. The NMR Research group also belongs to the European NMR Research Infrastructures (www.eu-nmr.eu), providing experimental NMR access to European groups.

We are searching for a researcher (post-doc) in computational biomolecular NMR.

Job description
---------------------
You will be part of a European team working toward the deployment and unification of the NMR computational infrastructure in system biology, a project funded under the 7th framework programme of the European Union (Contract no. 213010 – eNMR).
NMR plays an important role in life sciences (bio-NMR), and structural biology in particular, at both European and international levels. The main objective of this project is to optimize and extend the use of the NMR Research Infrastructures of EU-NMR through the implementation of an e-Infrastructure in order to provide the European bio-NMR user community with a platform integrating and streamlining the computational approaches necessary for bio-NMR data analysis (e-NMR). The e-NMR infrastructure will be based on the Grid infrastructure.
For this, you will work on the development of a uniformed and integrated e-NMR platform that will form the core of the e-NMR infrastructure. The work will be carried in close collaboration with our European partners.

Qualifications
-------------------
You should have a Ph.D. degree in chemistry, physics, bioinformatics, computational biology or a related field. You should possess a strong research background in the computational aspects of biomolecular NMR and structure calculations, experience with Linux and programming skills, and are expected to show initiative and be able to work independently.

Terms of employment
------------------------------
We offer initially a position for two years with a possible extension by one year. Salary is dependent on qualifications and experience and ranges from €2740.- to €3597.- gross per month (salary scale 10). The salary is supplemented with a holiday bonus of 8% per year and a year-end bonus of 3% per year. We also offer a pension scheme. Employment conditions are according to the Collective Labour Agreement of Dutch Universities.

Further details
--------------------
For further information contact Dr. Alexandre M.J.J. Bonvin (Phone: +31-30-2533859 Fax: +31-30-2537623 Email: a.m.j.j.bonvin@uu.nl).

How to apply
------------------
Your application, referring to vacancynumber 65720, including a CV with contact information of two referees, should be sent to Science.PenO@uu.nl or: Faculty of Science, Personnel department, PO Box 80010, 3508 TA Utrecht.

Freitag, 14. Dezember 2007

Post Doc Israel

Two post doc positions are available in the lab of Dr. Aharon Blank
at the Technion in the field of method developments in NMR and ESR.
Significant EU and local funding is expected to capable candidates.

Applicants should have high tendency to experimental/methodological
development work.

For further details, contact: Aharon Blank ab359@tx.technion.ac.il

Aharon Blank
Schulich Faculty of Chemistry
Technion - Israel Institute of Technology.
Haifa 32000
Israel
ab359@tx.technion.ac.il
Phone: +972-4-829-3679
Fax: +972-4-829-5948

Dienstag, 20. November 2007

Postdoc MRI

Post Doctoral Position
MRI Applications in Immune Mediated Tumor Response
Biological Imaging Center - Caltech
Division of Cancer Immunotherapeutics and Tumor Immunology (CITI) - City of Hope

This position is aimed at investigating MR imaging of immune mediated tumor responses with the goal of translating methodologies developed in small animal models to the clinic. We are interested in an individual who is firmly grounded in NMR theory and practice with an interest in applications in immunological approaches to cancer therapy including antibodies, immunocytokines, T-cells, dendritic cells, and small molecule drugs. This work will involve development and application of various MR methodologies at Caltech in coordination with researchers and physicians in the Division of Cancer Immunotherapeutics and Tumor Immunology at City of Hope ( http://www.cityofhope.org/citi).
The Biological Imaging Center and Caltech Brain Imaging Center ( http://bioimaging.caltech.edu/) are highly interdisciplinary endeavors with biologists, chemists, physicists, and engineers working on a number of animal models of disease and developmental processes. MRI facilities at Caltech include Bruker SpectroSpin 11.7T/89mm, 9.4T/30cm, 7T/30cm and 4.7T/60cm systems dedicated to research. There are also extensive facilities for all aspects of MRI hardware development and data analysis.

CITI at the City of Hope is focused on the development of Cancer Immunotherapeutics and has a long track record of developing novel therapeutics and conducting clinical trials. Current clinical trials include antibodies, immunocytokines, and T cells; all made in a cGMP compliant production facility housed on the campus. Clinical imaging includes a GE PET/CT GE 1.5T MR, and animal microPET and microCT.

Interested applicants with experience in small animal MRI should email, FAX, or mail a biosketch including names, addresses, & email addresses of three references to


Russell E. Jacobs, PhD
m/c 139-74 Caltech
1200 E. California Blvd
Pasadena, CA 91125-7400
rjacobs@caltech.edu
Phone: (626) 395-2863
Fax: (626) 449-5163

OR

Andrew Raubitschek, MD
Chair, Cancer Immunotherapeutics & Tumor Immunology
Beckman Research Institute of City of Hope
1500 East Duarte Rd.
Duarte, CA 91010
araubitschek@coh.org
Phone: (626) 256-4673 x62451
Fax: (626) 301-8817

Freitag, 16. November 2007

Postdoc Auckland

Postdoctoral fellow in NMR spectroscopy of membrane binding antimicrobial proteins

Applications are invited for a postdoctoral position in the group of Dr Andrew Dingley at the University of Auckland, New Zealand.

The position is available for a researcher to investigate the interactions between antimicrobial proteins and membrane model systems using solution and solid-state NMR spectroscopy. The project will also involve characterizing the assembly of the antimicrobial proteins on the membrane surface. The research is part of an international collaborative effort and is funded by a three year NZ Royal Society Marsden grant. Facilities include a fully equipped (including cryoprobe) 600 MHz high-resolution spectrometer and a protein preparation laboratory.

Highly motivated candidates should have (or about to receive) a PhD with experience in either biomolecular NMR spectroscopy, protein chemistry with a background in protein structure or membrane biophysics. Demonstrated strengths in protein expression and purification and basic skills in molecular biology are desirable.

Further information and informal enquiries can be made to Dr Andrew Dingley.

Interested applicants should email/send their applications including CV with the names and the contact details of at least two referees to:

Dr Andrew Dingley
Department of Chemistry/School of Biological Sciences
The University of Auckland
Private Bag 92019
Auckland Mail Centre
Auckland 1142
New Zealand

Email: a.dingley@auckland.ac.nz
Website: http://www.sbs.auckland.ac.nz/

Mittwoch, 31. Oktober 2007

Position in Illinois

Dear Colleagues,

The University of Illinois at Urbana-Champaign currently has an
opening for a Ph.D.-level spectroscopist in the School of Chemical
Sciences NMR Facility. Primary responsibilities are support of solid-
state NMR, instrument maintenance and repair, and interacting with
researchers on issues of experiment selection and data analysis.

The full ad is posted at http://www.scs.uiuc.edu/SCS/position/SOCS_NMR.pdf.

The formal application deadline is November 5.

We would appreciate your bringing this to the attention of qualified
graduate students and postdoctoral associates who are seeking
permanent employment.

Thank you.

Chad M. Rienstra
Assistant Professor of Chemistry
University of Illinois at Urbana-Champaign
600 South Mathews Avenue, Box 50-6
Urbana, IL 61801

Phone: 217 244-4655, Fax: 217 244-3186
Office: A120 CLSL, Lab: A125 CLSL
rienstra@scs.uiuc.edu
http://www.scs.uiuc.edu/~rienstra

Donnerstag, 25. Oktober 2007

Postdoctoral Position

Postdoctoral Position: Development of Novel Sample Media for Membrane Protein Structural Biology

The lab of Chuck Sanders at Vanderbilt University has an opening for a postdoctoral fellow to develop and test novel detergents and other membrane-mimetic medium as a means to facilitate membrane protein structural biology using NMR spectroscopy and/or X-ray crystallography. While this project has the potential to proceed to actual membrane protein structural determination it is expected that the first year of the project will be almost exclusively "wet lab" in nature, involving the testing and characterization of new media using a panel of test membrane proteins. The test protein set will include G protein-coupled receptors. This project represents an opportunity to obtain advanced training in practical methods for producing, purifying, reconstituting, and characterizing integral membrane proteins. Such skills are, arguably, just as important in membrane protein structural biology as the actual biophysical methods used to characterize protein structure and so this might be a good opportunity for an NMR expert who wants to expand her/his scientific horizon.

Candidates should be available to start a new position on or before January 1, 2008 and should send a curriculum vita, including contact information for references to:

Prof. Charles Sanders, Dept. of Biochemistry
Vanderbilt University Center for Structural Biology
Nashville, Tennessee 37232-8725 USA
Phone: (615)-936-3756
e-mail: chuck.sanders@vanderbilt.edu

Lab web site: http://structbio.vanderbilt.edu/sanders

Vanderbilt University is an equal opportunity employer.