Postdoc position SSNMR Leiden

The Solid-state NMR group of the Leiden Institute of Chemistry
invites applications for a

Postdoc position (up to 3 years).

Founded by the Research Fund for Coal and Steel of the
European Commission, within a research network coordinated
by the Fraunhofer-Institut Oberhausen, we aim to study
the absorptive properties of coal and link to a molecular
structure model.

Additional to a MAS NMR analysis of coal samples, optical
pumping of noble gasses in order to explore surface properties
is intended.

The solid-state NMR group in Leiden provides a comprehensive
infrastructure including various fields (MAS between 2.3 to 17.6 Tesla),
MRI, facilities for illumination in the magnet (Xe lamps, solid-state
lasers, OPO) and for low temperature experiments.

Interested candidates should have a strong background in
solid-state NMR, knowledge on optical methods is desirable,
interest on material science and the ability to work independently
within the network. The postdoc would be encouraged to build up
his/her own line of research. The position will be initially
offered for one year with the intension to extend to about three
years. The project can start immediately.

For information and application, please contact:
Dr. Jörg Matysik
j.matysik (at) chem.leidenuniv.nl
tel.: +31-71-527 4198


***************************************************
Dr. Joerg Matysik
Leiden Institute of Chemistry, University of Leiden
PO Box 9502, 2300 RA Leiden (mail)
Einsteinweg 55, 2333 CC Leiden (visit/courier)
The Netherlands
Tel.: +31-71-527-4198
Fax: +31-71-527-4603
j.matysik@chem.leidenuniv.nl
www.cidnp.net
****************************************************
Biophysical Techniques in Photosynthesis, Vol. 2
T.J. Aartsma & J. Matysik, eds. (2008)
http://www.springer.com/978-1-4020-8249-8
****************************************************

Assistant Professor Position New York University

Assistant Professor Position
New York University

The Department of Chemistry at New York University, located
in Greenwich Village in lower Manhattan, invites applications
for a tenure-track Assistant Professor position in experimental
biophysical chemistry and experimental physical chemistry
applied to macromolecular and biological systems. The
anticipated start date is September 1, 2009, pending
budgetary and administrative approval. The Department is
embarking on a significant growth plan that includes the
creation of the Molecular Design Institute, the recent hire of
two senior-level faculty with several more anticipated, and
expansion of laboratory and instrumentation facilities.
Applicants should have an outstanding record of research and
a commitment to teaching.

Applications should include a curriculum vita, a list of
publications, a statement of future original research and
teaching plans, and the names of at least three references.
Application review will begin on October 15, 2008.
Applications should be sent to Faculty Search Committee,
Department of Chemistry, New York University, 100
Washington Square East, New York, NY 10003.

20 Scholarships for PhD Studies in Structural Biology

NRW Research School at Heinrich- Heine-University Düsseldorf

The NRW Research School BioStruct - Biological Structures in Molecular Medicine and Biotechnology at Heinrich-Heine-University Düsseldorf in Germany, funded by the Ministry of Innovation, Science, Research and Technology of the German Federal State North Rhine-Westphalia (NRW), and the school chairmen Prof. Dr. Lutz Schmitt and Prof. Dr. Dieter Willbold invite applications for

20 Scholarships for PhD Studies in Structural Biology
applied to Molecular Medicine or Biotechnology

starting October 2008.

BioStruct offers innovative education and research programs within a stimulating interdisciplinary environment combining the fields of structural biology, molecular medicine and biotechnology.

Highly motivated and excellent candidates holding an MSc or Diploma degree in the fields of Biochemistry, Biology, Chemistry and related fields can directly apply for one of 20 PhD Scholarships including a monthly stipend of 1345,- EUR and contributions towards travel and research expenses.

Promising and exceptional candidates holding a BSc or MD can apply for one of 3 Qualifying Scholarships facilitating entrance qualification for the PhD-program within one year and including a monthly stipend of 800,- EUR.

For further information, prerequisites and application forms please visit our website: www.biostruct.de.

For enquiries and additional information please contact the managing director Dr. Christian Dumpitak: dumpitak@biostruct.de.

Applications are open throughout the year until all PhD and Qualification Scholarships are filled.

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Prof. Dr. Henrike Heise
Heinrich-Heine-Universitaet Duesseldorf
Forschungszentrum Juelich
INB-2 / Molekulare Biophysik II
D-52425 Juelich
Tel.:+49-2461-61-4658



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Forschungszentrum Jülich GmbH
52425 Jülich

Sitz der Gesellschaft: Jülich
Eingetragen im Handelsregister des Amtsgerichts Düren Nr. HR B 3498
Vorsitzende des Aufsichtsrats: MinDir'in Bärbel Brumme-Bothe
Geschäftsführung: Prof. Dr. Achim Bachem (Vorsitzender),
Dr. Ulrich Krafft (stellv. Vorsitzender), Prof. Dr. Harald Bolt,
Dr. Sebastian M. Schmidt
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Postdoc in Biomolecular SSNMR

Postdoc in Biomolecular SSNMR
A full-time Postdoctoral Fellow position is immediately available to
a highly motivated candidate to conduct research on structural
elucidation of membrane proteins (especially G-protein coupled
receptors) and pathological protein aggregates. A 600 MHz
Varian Inova spectrometer, which is equipped with fast MAS
and variable temperature capabilities, is available for this
Biomolecular Solid-State NMR research. For more information,
please visit http://physics.okstate.edu/zhou/.

Qualifications: Ph.D. in Physics, Chemistry or related fields.
The candidate is expected to have strong solid or solution NMR
background. Experiences with protein expression and purification
are a big plus.

To apply: Please send a cover letter, CV and the names and contact
information of three references to Dr. Donghua Zhou by email: donghua@okstate.edu.




Dr. Donghua Zhou
Assistant Professor
Department of Physics
Oklahoma State University
224 Physical Science
Stillwater, OK 74078

(405) 744-3277
donghua@okstate.edu
http://physics.okstate.edu/zhou/

Postdoctoral position in biological solid state NMR

Postdoctoral position in biological solid state NMR


A postdoctoral research position in biological solid state NMR is available at the Department of Structural Biology at the *University of Pittsburgh School of Medicine*. The group of Patrick van der Wel uses solid state NMR to study various biological topics, predominantly through the use of magic angle spinning (MAS) solid state NMR. Particular research interests inlcude (1) Structural membrane protein studies focused on the interplay between the lipids of the lipid bilayer and the membrane-bound protein, (2) Investigations of amyloid fibril structure and formation.

The group has specific access to Bruker 800 and 600MHz magnets, which are well-equipped for solid state NMR, with multiple MAS as well as static solid state NMR probes. The department also features collaborative research groups with expertise in a variety of structural techniques, including solution state NMR, (cryo) EM, and X-ray crystallography. It is housed in a new research building and includes state-of-the-art equipment and wet lab resources.

For more information see: *http://www.pitt.edu/~pvdwel/positions.html*
Or contact Patrick van der Wel at: pvdwel@pitt.edu

--
Patrick C.A. van der Wel, Ph.D.
Assistant Professor
Department of Structural Biology
University of Pittsburgh School of Medicine
Biomedical Science Tower 3, room 2044
3501 Fifth Ave.
Pittsburgh, PA 15260
e-mail: pvdwel@pitt.edu
http://www.pitt.edu/~pvdwel

Leitung NMR-Abteilung Organische Chemie Universität Stuttgart

Am Institut für Organische Chemie der Universität Stuttgart ist zum 01.02.2009 die Stelle eines/einer
Akademischen Rates/Akademischen Rätin (BesGr. A13)
für das Themengebiet NMR-Spektroskopie zu besetzen (Nachfolge PD Dr. Peter
Fischer).
Das Aufgabengebiet umfasst die Leitung der NMR-spektroskopischen Abteilung sowie
der Abteilung für IR-Spektroskopie und Gaschromatographie mit gegenwärtig 3-4
Angestellten. Eine Beteiligung an der Lehre und an der universitären Selbstverwaltung
wird erwartet. Bewerber sollten die Fähigkeit zur Leitung einer wissenschaftlichen
Arbeitsgruppe, Eigeninitiative sowie Erfahrung beim Umgang mit NMR-Spektrometern
mitbringen. Einschlägige Erfahrungen auf dem Gebiet der ein- und zweidimensionalen
NMR-Spektroskopie sind erwünscht. Es besteht die Möglichkeit zur selbständigen
Durchführung von Forschungsprojekten und der Habilitation.
Einstellungsvoraussetzung ist ein abgeschlossenes Hochschulstudium in den Fächern
Chemie oder Physik. Eine Promotion mit überdurchschnittlichem Erfolg sowie
internationale Publikationen werden vorausgesetzt.
Die Universität Stuttgart bietet eine unbefristete Vollzeitstelle in einem attraktiven
Umfeld mit der Möglichkeit einer weitgehend unabhängigen Gestaltung der Forschung.
Die Universität Stuttgart möchte den Anteil der Frauen erhöhen. Frauen werden deshalb
ausdrücklich zur Bewerbung aufgefordert. Vollzeitstellen sind grundsätzlich teilbar.
Schwerbehinderte werden bei gleicher Eignung vorrangig eingestellt. Die Einstellung
erfolgt durch die Zentrale Verwaltung.
Für Auskünfte steht Ihnen Prof. C. Richert (Tel. 0711 685 64311) gerne zur Verfügung.
Ihre Bewerbung mit den üblichen Unterlagen richten Sie bitte an die Geschäftsführende
Direktorin des Instituts für Organische Chemie, Frau Prof. Sabine Laschat,
Pfaffenwaldring 55, D-70569 Stuttgart. Die Bewerbungsfrist endet am 15.10.2008.

Leitung NMR-Abteilung Organische Chemie Hamburg

STELLENAUSSCHREIBUNG
Leitung NMR-Abteilung der Organischen Chemie
Ab 01.10.2008 ist die Stelle eines/einer
Akademischen Rates / Akademischen Rätin
der Besoldungsgruppe A13 mit 40 Stunden wöchentlich unbefristet zu besetzen.
Die Universität strebt die Erhöhung des Anteils von Frauen am wissenschaftlichen Personal an und fordert deshalb qualifizierte Frauen nachdrücklich auf, sich zu bewerben. Frauen werden im Sinne des Hamburgischen Gleichstellungsgesetzes bei gleichwertiger Qualifikation vorrangig berücksichtigt.
Aufgaben:
Die Stelleninhaberin oder der Stelleninhaber soll die NMR-Abteilung der Organischen Chemie kompetent leiten und den Service effizient mit den vorhandenen Ressourcen organisieren.
Weiterhin soll eine Strukturplanung für die weitere Entwicklung der NMR- Spektroskopie im hochauflösenden Bereich vorgenommen werden. Wissenschaftliche Weiterqualifikation und Präsentation wissenschaftlicher Ergebnisse werden erwartet. Einsatz in der Ausbildung von Studenten ist im Bereich der theoretischen und praktischen Qualifikation essentieller Bestandteil der Aufgaben.
Die Lehrverpflichtung beträgt 4 Semesterwochenstunden.
Qualifikation:
Erwartet werden umfangreiche theoretische und praktische Kenntnisse der modernen
hochauflösenden 1D- und 2D-NMR- Spektroskopie; praktische Fähigkeiten im Umgang mit
und im Service von NMR Spektrometern der Firma Bruker; Kenntnisse in der Organisation
einer Service-orientierten NMR -Abteilung; praxisorientierte Lösungen von spektroskopischen Problemen in der hochauflösenden NMR Spektroskopie; Erfahrungen in der Vermittlung von wissenschaftlichen Erkenntnissen an Studenten und Wissenschaftler; Lehrerfahrung in der NMR- Spektroskopie; Erfahrungen beim Einsatz von Software zur Aufklärung von 2D- und 3D-Strukturen aus NMR- Spektren.
Einstellungsvoraussetzungen:
Abgeschlossene Ausbildung an einer wissenschaftlichen Hochschule bevorzugt mit Promotion.
Schwerbehinderte haben Vorrang vor gesetzlich nicht bevorrechtigten
Bewerberinnen/Bewerbern gleicher Eignung, Befähigung und fachlicher Leistungen.
Bewerbungen mit den üblichen Unterlagen (Bewerbungsschreiben, tabellarischer Lebenslauf, Hochschulabschluss) werden bis zum 19.09.2008 erbeten an:
Prof. Dr. J. Thiem, Tel. (040) 42838-4241, Martin-Luther-King-Platz 6, 20146 Hamburg.
Für nähere Informationen sehen Sie bitte im Internet unter
www.verwaltung.uni-hamburg.de/stellenangebote
nach.

Postdoc in DNP NMR spectroscopy

*Postdoctoral Research Fellow in DNP NMR spectroscopy*

**Sir Peter Mansfield Magnetic Resonance Centre, School of Physics & Astronomy, University of Nottingham, UK
This post is funded by a BBSRC Technology Development Initiative grant with the main objective to develop DNP NMR strategies for the detection of molecular motion and dynamic processes. The project includes a) research in dissolution DNP, b) probehead design and rf coil design, c) development of pulse sequences for a multi-channel NMR spectrometer, and d) designing strategies for the investigation of fast molecular dynamics such as binding and folding and applying them to model protein systems.

Candidates must have a PhD in a relevant subject. Experience in NMR and/or ESR techniques and a good knowledge of NMR hardware compounds will be an advantage.

Salary will be within the range £25,888 – £33,780 per annum, depending on qualifications and experience (salary can progress to £36,912 per annum, subject to performance). This post will be offered on a fixed-term contract starting in autumn 2008 for a period of up to three years, depending on qualifications and experience.

Further details about this post and the project involved are available at: http://www.nottingham.ac.uk/~ppzwk/DNP .

*For more details please send an email to walter.kockenberger@nottingham.ac.uk
****Please quote ref. SCI/362X1. **Closing date: 22 September 2008.*


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NMR Spectroscopist South Africa

NMR Spectroscopist
Stellenbosch University, Stellenbosch (Cape Town area), South Africa
(Ref. 08AR302)

The Central Analytical Facility (CAF) hosts much of the large analytical equipment of Stellenbosch University within nine operational units. Equipment is managed independently within the CAF to ensure optimal utilisation and service to the research community of the University, as well
as the South African research and development sector in general.

The NMR Laboratory is one of the larger units within the CAF and is the best equipped NMR laboratory in South Africa. The laboratory houses three solution-state NMR spectrometers (300, 400 & 600 MHz) and a wide-bore 500-MHz dedicated solid-state NMR spectrometer. All spectrometers are Varian systems.

Together with other staff members of the unit, the NMR Spectroscopist will ensure that the unit functions to the best advantage of research at the institution.

Duties: Liaising with clients to assist with NMR spectroscopic problems, ranging from proposing appropriate experiments and running the experiments for clients (academic and commercial), to assisting with interpretation of spectra, providing practical training for students on the NMR spectrometers, assisting with the implementation of safety procedures in the laboratory, instrument maintenance and troubleshooting of instrument-related problems, assisting with the financial and functional administration of the laboratory.

Requirements: MSc in Chemistry - practical experience in solution-state NMR spectroscopy - knowledge of principles and theory of NMR spectroscopy - ability to interpret solution-state NMR spectra - ability to work independently in a service orientated environment - proven ability to handle multiple tasks under time pressure - sound oral and written communication skills.

Recommendations: PhD in Chemistry - experience in the use of Varian NMR spectrometers - a broad understanding of various areas of Chemistry in order to understand clients problems.

Commencement of duties: As soon as possible

Closing date: 5 September 2008

Enquiries: Gary Stevens on +27 21 808 3127 or email gs@sun.ac.za

The University will consider all applications in terms of its
Employment Equity Plan, which acknowledges the need to diversify the
demographic composition of the staff corps, especially with regard to
the appointment of suitable candidates from the designated groups.

The University reserves the right not to make an appointment.

A competitive remuneration package and excellent service benefits are
attached to this position. For further details, contact +27 21 808 4829.

Your full application, comprising
(1) a completed application form
(obtainable on our homepage or by e-mailing vacancies@sun.ac.za or contacting +27 21 808 4542) and
(2) a comprehensive curriculum vitae (including the names and contact
details of at least two referees), must reach the University before or
on the closing date of the advertised post.

Forward your application via e-mail to vacancies@sun.ac.za or to The
Manager: Personnel Provisioning & Planning, Stellenbosch University,
Private Bag X1, Matieland 7602, or fax +27 21 808 2484.

Should no feedback be received from the University within four weeks
of the closing date, kindly accept that your application did not succeed.

Postdoctoral Position in Biomolecular NM

Postdoctoral Position in Biomolecular NMR of partially folded and intrinsically unfolded proteins at the Institute of Structural Biology in Grenoble, France.


Two year postdoctoral position to work in NMR developments for the study of partially folded proteins at the Institute of Structural Biology in Grenoble (in the group of Martin Blackledge : Protein Dynamics and Flexibility by NMR).

Web site :

Current research interests lie in the study of conformational flexibility in proteins in their different forms, from intrinsically disordered proteins to folded globular proteins, and to understand the complex relationship between molecular motion and biological function and malfunction. Our principal tool is Nuclear Magnetic Resonance (NMR), combined with complementary biophysical techniques such as molecular simulation and small angle scattering. We are actively collaborating with a number of groups, allowing immediate application of developed techniques to biological paradigms involving dynamic or disordered systems. The key systems that we are studying are proteins involved in the development of neurodegenerative disease, viral proteins regulating transcription and replication and cancer-related proteins. Some relevant references listed below.


The Institute of Structural Biology houses three NMR spectrometers equipped with cryogenic probes (two 600 MHz and one 800 MHz) and the group collaborates closely with the nearby European high field NMR centre in Lyon with access to higher field instruments (900 MHz and 1 GHz NMR spectrometers by the end 2008). The NMR groups at the IBS also share access to a fully equipped wet lab for the preparation of isotopically labeled NMR samples.
Grenoble is a pleasant city situated in the heart of the French Alps and hosts one of Europe’s most vibrant structural biology communities comprising the European Synchrotron Radiation Facility (ESRF), the Laue Langevin Institute (ILL), the Structural Biology Institute (IBS) and the EMBL Grenoble Out-Station.

Previous experience in the study of biomolecular structure or dynamics using modern heteronuclear NMR spectroscopy techniques is considered an advantage, although candidates from complementary fields will also be considered.
A competitive salary (based on previous research experience) is offered with health insurance, retirement plan and language training allowance. Interested candidates should forward a curriculum vitae, list of publication and electronic and postal addresses of potential referees to martin.blackledge@ibs.fr



Quantitative Conformational Analysis of Partially Folded Proteins from Residual Dipolar Couplings : Application to the Molecular Recognition Element of Sendai Virus Nucleoprotein. Malene Ringkjøbing Jensen, Klaartje Houben, Ewen Lescop, Laurence Blanchard, Rob W.H. Ruigrok and Martin Blackledge. J.Am.Chem.Soc. 130, 8055-8061 (2008).
Structure of tumor suppressor p53 and its intrinsically disordered N-terminal transactivation domainMark Wells, Henning Tidow, Trevor J. Rutherford, Phineus Markwick, Malene Ringkjobing Jensen, Efstratios Mylonas, Dmitri I. Svergun, Martin Blackledge*, and Alan R. Fersht*. Proc. Natl. Acad. Sci. (U.S.A.) 105, 5762–5767 (2008).
Mapping the Conformational Landscape of Urea-Denatured Ubiquitin using Residual Dipolar Couplings. Sebastian Meier, Stephan Grzesiek and Martin Blackledge J.Am.Chem.Soc. 129, 9799-9807 (2007).
Highly Populated Turn Conformations in Natively Unfolded Tau Protein Identified from Residual Dipolar Couplings and Molecular Simulation. M. D. Mukrasch, P.R.L. Markwick, J. Biernat, M. von Bergen, P. Bernado, C. Griesinger, E. Mandelkow, M. Zweckstetter and M. Blackledge J.Am.Chem.Soc. 129, 5235-5243 (2007).
Exploring Multiple Timescale Motions in Protein GB3 using Accelerated Molecular Dynamics and NMR. P. Markwick, G. Bouvignies and M. Blackledge J.Am.Chem.Soc. 129, 4724-4730 (2007).


Martin Blackledge
Group Leader
Protein Dynamics and Flexibility by NMR
Institut de Biologie Structurale
41 Rue Jules Horowitz
Grenoble
38027
France
martin.blackledge@ibs.fr

Telephone: +33 438 789 554