A new postdoctoral position is becoming available at CEA Saclay (45 min by train from the center of Paris) in high-field multidimensional NMR applied to large biological assemblies, to be coupled with an exciting ANR granted project on the mechanisms of DNA gating in bacteriophages. The work is focussed on the molecular bases of the head-to-tail connector assembly and function in bacteriophage SPP1. It is based on functional and structural experiments, and in particular the coupling of liquid-state and solid-state Nuclear Magnetic Resonance, X-ray crystallography, Electron Microscopy and Molecular Modelling. Experience in advanced liquid-state and/or solid-state NMR is essential. Expertise in protein purification and molecular modeling will be useful. Starting date is from September 2011. A one year funding that can be extended to three years on a related project is available. Please submit application and CV to: sophie.zinn@cea.fr.
Dr Sophie Zinn-Justin
Laboratoire de Biologie Structurale et Radiobiologie
iBiTec-S, CEA Saclay
91190 Gif-sur-Yvette
http://www-dsv.cea.fr/dsv/instituts/institut-de-biologie-et-de-technologies-de-saclay-ibitec-s/unites/service-de-bioenergetique-biologie-structurale-et-mecanismes-sb2sm-ura-2096-cnrs/laboratoire-de-biologie-structurale-et-radiobiologie-lbsr/equipe-analyse-de-complexes-proteiques-par-rmn-et-cristallographie-b.-gilquin/projets-de-recherche/structure-de-l-enveloppe-nucleaire-interne-et-role-dans-la-signalisation-cellulaire-assemblage-de-grands-complexes-viraux-sophie-zinn-justin