Postdoc MRI

Post Doctoral Position
MRI Applications in Immune Mediated Tumor Response
Biological Imaging Center - Caltech
Division of Cancer Immunotherapeutics and Tumor Immunology (CITI) - City of Hope

This position is aimed at investigating MR imaging of immune mediated tumor responses with the goal of translating methodologies developed in small animal models to the clinic. We are interested in an individual who is firmly grounded in NMR theory and practice with an interest in applications in immunological approaches to cancer therapy including antibodies, immunocytokines, T-cells, dendritic cells, and small molecule drugs. This work will involve development and application of various MR methodologies at Caltech in coordination with researchers and physicians in the Division of Cancer Immunotherapeutics and Tumor Immunology at City of Hope ( http://www.cityofhope.org/citi).
The Biological Imaging Center and Caltech Brain Imaging Center ( http://bioimaging.caltech.edu/) are highly interdisciplinary endeavors with biologists, chemists, physicists, and engineers working on a number of animal models of disease and developmental processes. MRI facilities at Caltech include Bruker SpectroSpin 11.7T/89mm, 9.4T/30cm, 7T/30cm and 4.7T/60cm systems dedicated to research. There are also extensive facilities for all aspects of MRI hardware development and data analysis.

CITI at the City of Hope is focused on the development of Cancer Immunotherapeutics and has a long track record of developing novel therapeutics and conducting clinical trials. Current clinical trials include antibodies, immunocytokines, and T cells; all made in a cGMP compliant production facility housed on the campus. Clinical imaging includes a GE PET/CT GE 1.5T MR, and animal microPET and microCT.

Interested applicants with experience in small animal MRI should email, FAX, or mail a biosketch including names, addresses, & email addresses of three references to


Russell E. Jacobs, PhD
m/c 139-74 Caltech
1200 E. California Blvd
Pasadena, CA 91125-7400
rjacobs@caltech.edu
Phone: (626) 395-2863
Fax: (626) 449-5163

OR

Andrew Raubitschek, MD
Chair, Cancer Immunotherapeutics & Tumor Immunology
Beckman Research Institute of City of Hope
1500 East Duarte Rd.
Duarte, CA 91010
araubitschek@coh.org
Phone: (626) 256-4673 x62451
Fax: (626) 301-8817

Postdoc Auckland

Postdoctoral fellow in NMR spectroscopy of membrane binding antimicrobial proteins

Applications are invited for a postdoctoral position in the group of Dr Andrew Dingley at the University of Auckland, New Zealand.

The position is available for a researcher to investigate the interactions between antimicrobial proteins and membrane model systems using solution and solid-state NMR spectroscopy. The project will also involve characterizing the assembly of the antimicrobial proteins on the membrane surface. The research is part of an international collaborative effort and is funded by a three year NZ Royal Society Marsden grant. Facilities include a fully equipped (including cryoprobe) 600 MHz high-resolution spectrometer and a protein preparation laboratory.

Highly motivated candidates should have (or about to receive) a PhD with experience in either biomolecular NMR spectroscopy, protein chemistry with a background in protein structure or membrane biophysics. Demonstrated strengths in protein expression and purification and basic skills in molecular biology are desirable.

Further information and informal enquiries can be made to Dr Andrew Dingley.

Interested applicants should email/send their applications including CV with the names and the contact details of at least two referees to:

Dr Andrew Dingley
Department of Chemistry/School of Biological Sciences
The University of Auckland
Private Bag 92019
Auckland Mail Centre
Auckland 1142
New Zealand

Email: a.dingley@auckland.ac.nz
Website: http://www.sbs.auckland.ac.nz/

Position in Illinois

Dear Colleagues,

The University of Illinois at Urbana-Champaign currently has an
opening for a Ph.D.-level spectroscopist in the School of Chemical
Sciences NMR Facility. Primary responsibilities are support of solid-
state NMR, instrument maintenance and repair, and interacting with
researchers on issues of experiment selection and data analysis.

The full ad is posted at http://www.scs.uiuc.edu/SCS/position/SOCS_NMR.pdf.

The formal application deadline is November 5.

We would appreciate your bringing this to the attention of qualified
graduate students and postdoctoral associates who are seeking
permanent employment.

Thank you.

Chad M. Rienstra
Assistant Professor of Chemistry
University of Illinois at Urbana-Champaign
600 South Mathews Avenue, Box 50-6
Urbana, IL 61801

Phone: 217 244-4655, Fax: 217 244-3186
Office: A120 CLSL, Lab: A125 CLSL
rienstra@scs.uiuc.edu
http://www.scs.uiuc.edu/~rienstra

Postdoctoral Position

Postdoctoral Position: Development of Novel Sample Media for Membrane Protein Structural Biology

The lab of Chuck Sanders at Vanderbilt University has an opening for a postdoctoral fellow to develop and test novel detergents and other membrane-mimetic medium as a means to facilitate membrane protein structural biology using NMR spectroscopy and/or X-ray crystallography. While this project has the potential to proceed to actual membrane protein structural determination it is expected that the first year of the project will be almost exclusively "wet lab" in nature, involving the testing and characterization of new media using a panel of test membrane proteins. The test protein set will include G protein-coupled receptors. This project represents an opportunity to obtain advanced training in practical methods for producing, purifying, reconstituting, and characterizing integral membrane proteins. Such skills are, arguably, just as important in membrane protein structural biology as the actual biophysical methods used to characterize protein structure and so this might be a good opportunity for an NMR expert who wants to expand her/his scientific horizon.

Candidates should be available to start a new position on or before January 1, 2008 and should send a curriculum vita, including contact information for references to:

Prof. Charles Sanders, Dept. of Biochemistry
Vanderbilt University Center for Structural Biology
Nashville, Tennessee 37232-8725 USA
Phone: (615)-936-3756
e-mail: chuck.sanders@vanderbilt.edu

Lab web site: http://structbio.vanderbilt.edu/sanders

Vanderbilt University is an equal opportunity employer.

Postdoctoral Position - Marseille

Postdoctoral Position
Center for Magnetic Resonance in Biology and Medicine (CRMBM),
University of the Mediterranea, Marseille, France
The Center for Magnetic Resonance in Biology and Medicine (Centre de Résonance
Magnétique Biologique et Médicale : CRMBM), located at the University Hospital of la
Timone in Marseille (Director: P.J. Cozzone) is offering a post-doc position (18-24 months)starting January-May 2008. The position is in the "Muscle Group" headed by D. Bendahan and is funded by the ANR (National Agency for Research).
The CRMBM is located on the Campus of the Medical School in Marseille, adjacent to the University Hospital of la Timone, the largest medical facility in Southern Europe. It is jointly operated and funded by CNRS (National Center for Scientific Research), University of the Mediterranea and the Public Hospital System of Marseille.
The research project is devoted to the role of uncoupling proteins (UCP3) in skeletal muscle energetics. Several experimental measurements are planned including muscle energy metabolism, muscle performance, whole body fatty acid metabolism, UCP3 gene expression and mitochondrial electron chain transport.
Experiments will be conducted in UCP3-knockout mice and in rats chemically treated in order to reduce UCP3 expression. Muscle function will be studied strictly noninvasively in a 4.7 T Bruker Avance MR system, using 31P-MRS, MRI and measurements of muscle performance.
Whole body fatty acid metabolism will be investigated through measurements of body fat accumulation using MRI and plasmatic level of free fatty acid. Expression of UCP3 gene will be evaluated using quantitative real-time RT-PCR analysis. Mitochondrial electron chain transport activity will be measured using oxygraphy in biopsy samples.
This multiparametric study will give major information related to the control of energy expenditure in relation to UCP3 expression. Future potential applications related to body weight maintenance might be developed.
The successful applicant should have experience in muscle research preferably with MR
techniques. Applicants should send a Statement of Research Interests, a Curriculum Vitae, and 3 references to :
D. Bendahan
Centre de Resonance Magnetique Biologique et Medicale
UMR CNRS 6612
Faculte de Medecine de la Timone
27, Bd Jean Moulin
13005 Marseille
david.bendahan@univmed.fr
http://crmbm

Postdoctoral and PhD Student Position, University of Basel

Postdoctoral and PhD Student Position
University of Basel

A postdoctoral and a PhD student position are available in the group of Dr. Stephan Grzesiek at the Biozentrum Basel.

We are interested in the application and development of modern NMR methods for obtaining structure/function information on proteins and their complexes. One of our projects focuses on structural studies of HIV entry into T-cells. Facilities include fully equipped 800 MHz (cryo) and 600 MHz high-resolution spectrometers as well as a protein expression lab.

Highly motivated candidates with experience in macromolecular NMR, method development for solution or solid state NMR, membrane biophysics, molecular biology or protein chemistry with a background in structure should e-mail their application including CV and the name of the two references to:

Prof. Stephan Grzesiek
Biozentrum, University of Basel
Klingelbergstrasse 70
CH-4056 Basel, Switzerland
e-mail: stephan.grzesiek@unibas.ch
http://www.biozentrum.unibas.ch/grzesiek.html

NYU Faculty Position, Biophysical chemistry

Dear Colleagues,
NYU is searching to fill a faculty position in biophysical chemistry, broadly defined. Biophysical NMR spectroscopy is an option greatly favored. I would therefore be grateful if you could pass on the attached announcement to potentially interested
candidates. The ad is currently running in several publications. For junior candidates, I also recommend arranging for reference letters, even though the ad says only to list names. This would facilitate the process due to the late deadline. As mentioned in the ad, we would also consider senior applicants for this position and would welcome your suggestions.
Thank you very much
Alexej Jerschow


FACULTY POSITION
junior or senior
BIOPHYSICAL CHEMISTRY


The Department of Chemistry at New York University, located in Greenwich Village in lower Manhattan, invites applications for a faculty position in experimental biophysical chemistry. Strong candidates in other fields of experimental chemistry will also be considered, especially in areas of nanoscience and materials chemistry. The appointment will begin in the Fall of 2008, pending final administrative and budgetary approval.

All ranks will be considered, but applications from junior faculty candidates are preferred. The Department is embarking on a significant growth plan that includes the creation of the Molecular Design Institute, the recent hire of two senior-level faculty with more anticipated, and expansion of laboratory and instrumentation facilities. Applicants should have a very strong research record and a commitment to teaching. Applications should include a curriculum vita, a list of publications, a statement of future original research and teaching plans, and the names of at least three references. Application review will begin on November 15, 2007. Therefore, to guarantee full consideration complete applications should be sent by this date to

Faculty Search Committee
Department of Chemistry, New York University
100 Washington Square East, New York, NY 10003

NYU encourages applications from women and members of minority groups.

Postdoc in Maryland

Postdoctoral Position
University of Maryland

Postdoctoral position is available immediately in the group of
Dr. Vitali Tugarinov at the Dept. of Chemistry & Biochemistry,
University of Maryland, College Park
(http://www.chem.umd.edu/faculty/tugarinov/index.html).

Candidates should preferably have experience in one or several of the
following areas: biomolecular NMR spectroscopy, protein NMR methodology,
protein (bio)chemistry, molecular modeling/structure calculations.

The dedicated biomolecular NMR facility in the Center of Biomolecular
Structure and Organization features two 600 MHz instruments (one
cryo-probed) and the adjacent laboratory is fully equipped for protein
expression and sample preparation. Access to higher field instrumentation
at nearby universities is possible. University of Maryland-CP is situated
in close proximity to Washington, D.C., Baltimore, and Maryland's I-270
Technology Corridor with an easy access to vast research resources and
facilities, including those of the NIH, FDA, USDA and NIST.

Applicants may e-mail their CV to vitali@umd.edu or call 301-405-1504.

Assistant/Associate Professor

Assistant/Associate Professor:

Conservation Science, Spectroscopy/NMR

The Department of Mathematics and Science at Pratt Institute is looking for a scientist to fill a tenure track position at Assistant or Associate Professor level begining in the Fall 2008. The successful candidate should hold a Ph.D in Chemistry, Physics or Materials Science and should have a strong interest in contributing to an expanding collaborative research and teaching program in the Science of Art Conservation (Conservation Science) funded, in part, by the Alfred P. Sloan Foundation. The candidate is expected to teach and develop new courses in his/her field of expertise as it applies to Art, Design, and/or Art Conservation and to participate in research projects in the area of Conservation Science. Experience in NMR and/or Conservation Science in a museum setting is a plus. For more information, please contact Prof. Eleonora Del Federico, edelfede@pratt.edu.

POSTDOCTORAL POSITION - NMR/MRI - New York University

POSTDOCTORAL POSITION
NMR/MRI
New York University

We are looking to fill a postdoctoral position starting January 2008 (or later) on
technique development in 23Na NMR/MRI and 1H CEST NMR/MRI at New
York University. The ideal candidate will have experience in NMR theory
and experimental work. Experience with solid-state NMR, MRI, Diffusion
NMR, quadrupolar NMR, programming will be of advantage, although are
not requirements. The postdoc will be able to acquire experience working
with high-field MRI scanners (7T) at the Center for Biomedical Imaging.
New York University’s Chemistry Department is located at the heart of
Manhattan in Greenwich Village. The project will be performed jointly
between the NYU Chemistry Department (A. Jerschow) and the NYU
School of Medicine (R. R. Regatte).

The initial appointment is for 1.5 years, with possible extension. Applicants
should send their application including CV, a publication list, and names
and contact information of two references who would be willing to comment
on their work to alexej.jerschow at nyu.edu.

Dr. Alexej Jerschow
Chemistry Department
New York University
100 Washington Square East
New York, NY 10003
alexej.jerschow at nyu.edu
http://www.nyu.edu/projects/jerschow