The NMR group at the Centre de Biochimie Structurale (CBS) in Montpellier (France) is looking for a highly motivated researcher to join the team as a post-doc to work for two years on a project funded by the Chaires d’Excellence program of the French Research Funding Agency (ANR). The project, leaded by Pau Bernadó, aims the structural and dynamic characterization of a family of intrinsically disordered proteins linked to neurodegenerative diseases, and to reveal the molecular basis of the aggregation process causing these pathologies. This objective will be achieved by the integration of NMR, SAXS and single-molecule FRET data into novel computational approaches.
The successful candidate should have a PhD in chemistry, biology or physics and experience in solution state biomolecular NMR spectroscopy. Previous experience with protein expression and purification will be considered favourably. Knowledge in other biophysical techniques and computational methods will be favourably evaluated.
The laboratory hosts high-field state-of-the-art NMR spectrometers for biomolecular applications: A 700 MHz and a 500 MHz both equipped with cryoprobes and a 600 MHz. In addition to NMR, the CBS has an outstanding infrastructure covering all techniques for structural biology and biophysics including X-ray crystallography, cryo-electron microscopy, advanced fluorescent and super-resolution microscopes, single-molecule manipulation, molecular and cell biology, and high-performance computation.
Montpellier is a major biology area with a focus on basic research, biomedicine, plant biology and environmental science. Its science drive, the beauty of the region and its high quality of life, and the short commute to other major regional research areas (Barcelona, Paris, Toulouse, Marseille) make it an ideal destination for scientists from all over the world.
Applications and informal queries about the project and the lab should be addressed to Pau Bernadó (pau.bernado@cbs.cnrs.fr). Interested candidates should send their CV and the names of persons willing to write a recommendation letter in a cover letter describing their research interests and motivation.
Pau Bernadó, PhD
Group Leader
Centre de Biochimie Structurale
29, rue Navacelles
34090 Montpellier
France
Tel. +33(0)467417912
e-mail: pau.bernado@cbs.cnrs.fr