Dienstag, 20. November 2007

Postdoc MRI

Post Doctoral Position
MRI Applications in Immune Mediated Tumor Response
Biological Imaging Center - Caltech
Division of Cancer Immunotherapeutics and Tumor Immunology (CITI) - City of Hope

This position is aimed at investigating MR imaging of immune mediated tumor responses with the goal of translating methodologies developed in small animal models to the clinic. We are interested in an individual who is firmly grounded in NMR theory and practice with an interest in applications in immunological approaches to cancer therapy including antibodies, immunocytokines, T-cells, dendritic cells, and small molecule drugs. This work will involve development and application of various MR methodologies at Caltech in coordination with researchers and physicians in the Division of Cancer Immunotherapeutics and Tumor Immunology at City of Hope ( http://www.cityofhope.org/citi).
The Biological Imaging Center and Caltech Brain Imaging Center ( http://bioimaging.caltech.edu/) are highly interdisciplinary endeavors with biologists, chemists, physicists, and engineers working on a number of animal models of disease and developmental processes. MRI facilities at Caltech include Bruker SpectroSpin 11.7T/89mm, 9.4T/30cm, 7T/30cm and 4.7T/60cm systems dedicated to research. There are also extensive facilities for all aspects of MRI hardware development and data analysis.

CITI at the City of Hope is focused on the development of Cancer Immunotherapeutics and has a long track record of developing novel therapeutics and conducting clinical trials. Current clinical trials include antibodies, immunocytokines, and T cells; all made in a cGMP compliant production facility housed on the campus. Clinical imaging includes a GE PET/CT GE 1.5T MR, and animal microPET and microCT.

Interested applicants with experience in small animal MRI should email, FAX, or mail a biosketch including names, addresses, & email addresses of three references to

Russell E. Jacobs, PhD
m/c 139-74 Caltech
1200 E. California Blvd
Pasadena, CA 91125-7400
Phone: (626) 395-2863
Fax: (626) 449-5163


Andrew Raubitschek, MD
Chair, Cancer Immunotherapeutics & Tumor Immunology
Beckman Research Institute of City of Hope
1500 East Duarte Rd.
Duarte, CA 91010
Phone: (626) 256-4673 x62451
Fax: (626) 301-8817

Freitag, 16. November 2007

Postdoc Auckland

Postdoctoral fellow in NMR spectroscopy of membrane binding antimicrobial proteins

Applications are invited for a postdoctoral position in the group of Dr Andrew Dingley at the University of Auckland, New Zealand.

The position is available for a researcher to investigate the interactions between antimicrobial proteins and membrane model systems using solution and solid-state NMR spectroscopy. The project will also involve characterizing the assembly of the antimicrobial proteins on the membrane surface. The research is part of an international collaborative effort and is funded by a three year NZ Royal Society Marsden grant. Facilities include a fully equipped (including cryoprobe) 600 MHz high-resolution spectrometer and a protein preparation laboratory.

Highly motivated candidates should have (or about to receive) a PhD with experience in either biomolecular NMR spectroscopy, protein chemistry with a background in protein structure or membrane biophysics. Demonstrated strengths in protein expression and purification and basic skills in molecular biology are desirable.

Further information and informal enquiries can be made to Dr Andrew Dingley.

Interested applicants should email/send their applications including CV with the names and the contact details of at least two referees to:

Dr Andrew Dingley
Department of Chemistry/School of Biological Sciences
The University of Auckland
Private Bag 92019
Auckland Mail Centre
Auckland 1142
New Zealand

Email: a.dingley@auckland.ac.nz
Website: http://www.sbs.auckland.ac.nz/