Freitag, 31. Juli 2009

post doctoral position France

A joint post doctoral position (12 months) is available at the Commissariat de l'Energie Atomique (IRAMIS laboratory, CEA, Saclay, France – Dr. Dimitris Sakellariou) and Laboratoire de Chimie de la Matière Condensée de Paris (LCMCP - University P. et M. Curie, Paris, France – Pr. Christian Bonhomme).

START: september-october 2009

The title of the project is "NanoMACS" and deals with the study of nanomaterials [1] by the newly invented technique: "Magic Angle Coil Spinning" [2]. This project is funded by the CNano Ile de France consortium (see: and is a great challenge in terms of instrumentation / sensitivity in solid state NMR.

MACS is a straightforward approach to increase the NMR sensitivity and opens new opportunities for the study of small amount of samples (thin oxide films with nanometric thickness, small biosamples …). MACS will be developed at very high field (700 MHz), very fast MAS rotation (24 kHz), and for a large range of frequencies (1H, 31P, 27Al …). Double resonance experiments and homonuclear decoupling will be extended to MACS. Small samples containing expensive isotopes such as 43Ca, 29Si, 17O… will be studied by MACS.

All materials (including films) will be synthesized at the LCMCP (Paris), as well as the 700 MHz experiments. The instrumentation and experiments at 300 and 500 MHz will be performed at IRAMIS (Saclay).

[1] C. Bonhomme, C. Coelho, N. Baccile, C. Gervais, T. Azaïs, F. Babonneau, Accounts Chem. Res., 40 (2007) 738.

[2] D. Sakellariou, G. Le Goff, J. F. Jacquinot, Nature, 447 (2007) 694.


Donnerstag, 30. Juli 2009

Ph.D. studentship at Nottingham Trent University

Fully funded Ph.D. studentship at Nottingham Trent University

A PhD studentships is available in the following area:
· Portable MRI scanner for security applications

Minimum entry requirement: a first class or upper second class Honours degree (or equivalent) or Masters degree in one of the Physical Sciences (Physics, Chemistry, Materials, Forensic Science), Engineering Sciences (Electrical and Electronic), or related subjects.

Award: the studentship offers a stipend at Research Council rates (tax free) for 3 years and Home/EU student fees.

Eligibility: applicants from the UK or from an EU country are eligible for a full award of stipend and tuition fees. International candidates are not eligible to apply for this studentship.

Informal enquiries, please contact:

Prof. Carl Brown
E-mail :
Tel : 44 (0)115 8483184

For an application form, please contact:
Mrs Doreen Corlett
Research & Graduate Studies Office
Erasmus Darwin Building
Nottingham Trent University
Clifton Lane
Nottingham NG11 8NS
Telephone: +44 (0)115 848 3269

Please return completed applications, with copies of academic certificates, to Doreen Corlett by Friday 31 July 2008.

The studentships are offered in the School of Science. All our research units were rated as internationally recognised in the last Research Assessment Exercise (2008) and this included research rated as world-leading in Unit of Assessment 25 (please see below). We currently hold twenty three million pounds in external funding which includes a leading EU grant of 4.2 million Euros for research into cancer immunotherapy, the Anthony Nolan Trust cord blood programme and the £7.6m John van Geest Centre to research cancer vaccines (

The academic staff, together with over 50 postdoctoral fellows and 100 research students, support a large Graduate School which provides opportunities for study on PhD/MPhil and Masters by research programmes in a stimulating and caring environment (

Our Cutting Edge Research portfolio in the Physics and Electronic Engineering currently includes £3.2m funding for such diverse areas as: displays and photonics; X-ray security imaging; solid state lighting; and applications of optical coherence tomography, optical tweezers, acoustic wave sensors, superhydrophobic surface treatments and MRI imaging. NTU Physics holds a prestigious EPSRC Platform Grant: the recipients of these Grants are required to have an Internationally-Leading reputation and to hold a substantial research grant funding portfolio.

(please see:

Physics staff were entered in an Engineering and Physical Sciences submission into RAE2008 under Unit 25. Our submission was rated as having research that is 95% "Internationally Recognised" of which 40% is "Internationally Leading" and a further 15% is "World-leading". This places us joint 14th out of all the 52 universities in this unit in the UK according to the Times Higher Education Supplement.

Further particulars of the studentship

Portable MRI scanner for security applications

This project will produce a non-invasive detection technique for dangerous substances (hazardous, flammable or explosive liquids) in sealed containers. Low cost and portable magnetic resonance will be used to measure the T1/T2 relaxation times and the effective self-diffusion coefficient of the hydrogenated molecules present in a liquid (or a soft solid) under investigation. These parameters together offer a 'fingerprint' that may be measured through both transparent and optically opaque sealed containers. By limiting the capability of the magnetic resonance hardware to just the measurements of these properties, extremely low cost and highly portable devices for security screening will be developed.

Please contact : Dr. Martin Bencsik
E-mail: Tel: 0115 8488057

PhD, University of Marseille, France

A PhD position is available immediately at the University of Marseille France.

The thesis would concern the application of NMR to the analysis of complex mixtures, using multidimensional and diffusion (DOSY-like) experiments.

The ideal candidate will have a training in Physical/Analytical chemistry and a strong interest towards research.

Please contact



- Simplified Analysis of Mixtures of Small Molecules by Chromatographic NMR SpectroscopyGuilhem Pages, Corinne Delaurent, and Stefano Caldarelli, Angew. Chem. 2006, 45 , 5950-5953

- Improved 3D DOSY-TOCSY experiment for mixture analysis S. Viel and S. Caldarelli Chem. Comm. 2008, 2013-2015

- Chomatographic NMR in NMR solvents C. Carrara, G. Excouffier, C. Delaurent,S. Viel, S. Caldarelli J. Magn. Reson. 2008, 194, 303-306

Dienstag, 14. Juli 2009

Post Doc - MicroMRI Applications in Neurobiology

Post Doctoral Position
MicroMRI Applications in Neurobiology
Biological Imaging Center
California Institute of Technology

Post Doctoral Position for Fall/Winter 2009. This position is aimed at development and application of high resolution MRI in small animal models of neurotransmitter dysfunction and neurodegenerative disease. The Biological Imaging Center and Caltech Brain Imaging Center ( are highly interdisciplinary endeavors with biologists, chemists, physicists, and engineers working on a number of animal models of disease and developmental processes. We are interested in an individual who is firmly grounded in NMR theory and practice with an interest in applications in neurobiology. This work will involve various MR methodologies in rodent model systems; including fMRI, DTI and tract tracing with Mn2+ enhanced MRI, as well as simultaneous µMR/µPET imaging. Small animal MRI facilities at Caltech include a 11.7T/89mm scanner and a 7T/30cm scanner with µPET insert. There are also extensive facilities for all aspects of MRI hardware development and data analysis.

Interested persons should email or mail a biosketch including names, addresses, & email addresses of three references to

Russell E. Jacobs, PhD
m/c 139-74 Caltech
1200 E. California Blvd
Pasadena, CA 91125-7400

California Institute of Technology is an equal opportunity/affirmative action employer and encourages the applications of qualified women, minorities, veterans and disabled persons.

Mary Flowers California Institute of Technology
Fraser & Bronner-Fraser Lab Mom MC 139-74
Phone: (626) 395-2863 1200 E. California Blvd.
FAX: (626) 449-8599 Pasadena, CA 91125 USA

2 year post-doc in Orsay

Post-doctoral position in the Structural Biology team of Institut Curie/INSERMU759

The two-year post-doc program is dedicated to the study of internal dynamics of proteins in the microcrystalline form using dedicated NMR methods. In recent years it has become possible to determine protein structures in the solid state. In addition, recent observations suggest that internal dynamics may be also accessed in theses conditions. In particular, 15N spin relaxation rates have been measured in small proteins. This demonstrates the existence of motional processes on NMR time scales that are significantly longer that those accessible by liquid NMR.
The first NMR experiments will be done on the human protein centrin 2, and his C-terminal domain in complex with a target peptide (P17-XPC). In a second step other biologically relevant proteins will be studied. The candidate will endeavour to prepare the samples (protein expression, purification) and will participate to crystallization and NMR experiments. The structural and molecular characterization of studied proteins (structural changes, structural stability, interactions) in relation with the biological function will be done in our laboratory.
The post-doc project will be performed in close collaboration with partners from CEA Saclay and Ecole Normale Supérieure de Paris. Good knowledge in protein biochemistry (bacterial overproduction, purification), physicochemical analysis and NMR will be highly valued. The post-doctoral researcher will have the opportunity to participate to sample preparation and solid state dynamics NMR experiments. The post-doc position will be supported by a grant that has been awarded by the French Agence National de la Recherche (ANR).
Interested cndidates should send a CV and the names of two potential referees to:

Post Doc Toulouse

The Biomedical NMR group (Université Paul Sabatier, Toulouse,
France) is seeking for a young researcher who would like to apply for
researcher individual grant) from ARC (Association pour la Recherche
sur le Cancer, French Cancer Research Association). He/she will
pursue our work on NMR-based metabolomics of radioresistant brain
The successful candidate should have a PhD in Molecular Biology
(cancer). An additional experience in NMR would be strongly
For additional information, contact by e-mail Myriam MALET-MARTINO
( or dial 33 5 61 55 68 90

Groupe de RMN Biomédicale
Laboratoire SPCMIB (UMR CNRS 5068)
Université Paul Sabatier
118, route de Narbonne
31062 TOULOUSE cedex 9
tél: 33 (0)5 61 55 68 90
fax: 33 (0)5 61 55 76 25
- Responsable de la Mention STS Chimie du Master 1 et 2 de l'UPS
- Co-responsable de la Licence CBPS (Chimie-Biologie-Physique-Santé)
- Responsable du Programme Master 211 pour l'UPS

Donnerstag, 2. Juli 2009

Postdoctoral Position in DNP-Enhanced MAS Solid State NMR

Postdoctoral Position in DNP-Enhanced MAS Solid State NMR Studies of the Mechanism of Energy Transduction by Bacteriorhodopsin.

A postdoctoral position will be available in late 2009 for studies of the structures of cryotrapped intermediates in the ion-motive photocycle of bacteriorhodopsin. The appointment will be at Brandeis University for spectroscopy to be carried out at the MIT/Harvard Center for Magnetic Resonance, as part of a long-term collaboration between the Herzfeld group at Brandeis and the Griffin group at MIT. (The two institutions are a few miles apart in the Boston area.) The one-year appointment will be annually renewable by mutual consent.

A strong background in NMR spectroscopy is required. Interested individuals should send a CV and the e-mail addresses of three references to