Dienstag, 28. Dezember 2010

MRI Programmer

MRI Programmer

We seek a PhD graduate or equivalent to help develop a new MRI prototype based on a small-scale superconducting magnet, The position will suit someone with a background in MRI and NMR physics or engineering, who is interested in working in a more applied environment. The position is for two years, based in Wellington New Zealand, but the possibility exists for further employment in commercialisation work.

The MRI Programmer will be responsible for a range of software and MRI pulse sequence development, hardware construction, electronic and electromagnetic engineering, application design, technical documentation and support activities around the MRI system. The work will involve aspects of the whole range of NMR and MRI from engineering to data processing. The appointee will also assist in applications development for other prototype NMR systems developed by the team.

In addition to a good understanding of NMR, applicants should have good software programming skills, and a knowledge of Matlab, C++, and the Windows environment.

Applications, including a CV, a covering letter explaining the candidates interest in the job, and the names and email addresses of two referees, should be addressed to Professor Paul Callaghan, Victoria University of Wellington, New Zealand, and sent by email (paul.callaghan@vuw.ac.nz). Applications close on 31 January, 2011.

For more information, please visit


Manager of Science and Technology (M/F), Portugal

Within the framework of the Portuguese National Nuclear Magnetic
Resonance Network (PTNMR), Centro de Química da Madeira (CQM),
Funchal, Madeira Island, Portugal, is seeking for a Manager of Science
and Technology (M/F), holding a PhD in Chemistry (or related fields)
with NMR experience, to be responsible for the technical maintenance of
a 400MHz NMR equipment, analytical services, teaching and research. The
offered position is ideal for PhDs with strong NMR experience and
interest in the field of Natural Products and/or Materials.
Salary: The monthly salary will be between 1495€ (for the first year)
and 1995€ (depending on performance) plus a personal accident
insurance. The contract offered, will have duration up to December 2012.

Additional support will be provided, including office and laboratory
space, plus access to the National Networks of Nuclear Magnetic
Resonance, Mass Spectrometry and Nanotechnology. The right candidate
will also be given the opportunity to participate in
national/international scientific conferences as well as in the
research projects under development at CQM.

Candidate Profile: PhD in Chemistry, Physics, Biochemistry, Materials
Sciences or related areas with strong experience in liquid NMR.
Application Deadline: 31 of January 2011, 17h Lisbon time. Applications
should be submitted by e-mail (cqm@uma.pt), with the following
information: a. Motivation letter; b. A brief statement of the
applicant current and future research interest (Max. 2 A4 pag.);
c. Detailed Curriculum Vitae;
d. Academic certificates in Portuguese or translated to English
(certificated translation); e. Working program to be developed in the
scope of the Natural Products and/or Materials Groups of CQM (Max. 2 A4
pag.); f. Name and e-mail contacts of two referees. For further
details, candidates should consult CQM web pages at
http://bit.ly/dg6Nic or contact Prof. João Rodrigues by e-mail:

Marie-Curie funded studentships / postdoc positions at Weizmann

In connection to the recent signing of the FP7 Marie Curie Initial Training Network (ITN) METAFLUX - Metabolic Flux Analysis and Cancer, I am looking to hire suitable Ph.D. students or post-doctoral researchers in support of work to be carried out at Weizmann within the 2011-2015 calendar years. These hirings are mainly aimed at citizens of the European Union and/or Associate Member states, who qualify for a full employment contract along with mobility, travel and career development allowances. These are salaries fundable according to the (very generous) Marie Curie rules, which can be found in ftp://ftp.cordis.europa.eu/pub/fp7/docs/wp/people/m_wp_201002_en.pdf.

Depending on their status and interests, candidates would enter the Weizmann's Institute PhD or postdoctoral programs, under my supervision (Chemical Physics Department, Faculty of Chemistry) –and in certain cases coadvised by Prof Hadassa Degani (Biological Regulation Department, Faculty of Life Sciences). The candidate’s research would deal with a number of multidisciplinary problems within the field of magnetic resonance; particularly in connection to the use of hyperpolarized nuclei towards in vitro, in cell and biological NMR and MRI characterizations. Our aim is to bring together complementary aspects of dynamic nuclear polarization, and advanced in cell / in vivo MRI/NMR spectroscopies, towards the development of new methodologies to better understand and characterize cancer metabolism. If interested in pursuing a PhD at the Weizmann, the candidate should also have a strong curriculum, a good motivation, and a willingness to be exposed to a variety of topics in magnetic resonance. Background in at least one of the above-mentioned research areas (at a Ph.D. level) is required for a post-doctoral appointment. The training program will include in either case state-of-the-art activities such as network-wide courses, attendance/participation in a variety of workshops, and training experiences in other partner laboratories within the network. Further information on both our graduate or postdoctoral programs, can be found at http://www.fgs.org.il/en/.

The Weizmann Institute is located in a small, affordable and friendly town at the feet of the Judean hills, and is one of Israel's premier scientific institutions. It is a research center whose official language is English and which offers numerous facilities to international visitors, including furnished apartments for students and postdocs. From its inception the Institute has shown an unequivocal commitment to all areas of magnetic resonance and over the years it has made extensive investments in NMR faculty, staff and in infrastructure. As a result the Institute possesses an 800 MHz NMR with a cryoprobe, a 600 MHz widebore triple-resonance solids/liquids/imaging machine, a 3 T whole-body MRI scanner, a 95 GHz pulse EPR spectrometer, 4.7 and 9.4 T animal MRI scanners, an OI Hypersense DNP, para-hydrogen NMR facilities, and numerous (dozens) of other NMR instruments placed in various magnetic resonance buildings as well as several groups involved in all areas of magnetic resonance. The incorporation of significant new MR hardware is also in progress. Those interested in being considered for these positions should send their Vitae and at least two References to lucio.frydman@weizmann.ac.il.

Postdoc Positions

Postdoctoral Opportunities: Structural Biology in Ubiquitination and Signaling

The Macromolecular NMR Section in the Structural Biophysics Laboratory has openings for postdoctoral fellows to work in the structural biology of protein complexes related to ubquitination, Arf proteins, and signaling via the STAT proteins. Our laboratory is involved in the application and development of state-of-the-art NMR spectroscopy, SAXS, and biophysics techniques to determine protein structures, investigate critical protein:protein interactions relevant to biological systems, analyze dynamic processes, and integrate these studies with molecular and cellular biology. We collaborate interactively with several biological, structural, and chemical groups in the Center for Cancer Research. Excellent NMR facilities (500-850 MHz), protein expression capabilities, and computational facilities are available.

Interested applicants should have a background in structural biology and experience in NMR spectroscopy. For examples of our work, please see Das, R., et al., Mol. Cell 34(6):674-685 (2009) and Das, R., et al., J. Mol. Biol. 376(3):705-720 (2008).

R. Andrew Byrd, Chief [byrdra@mail.nih.gov]
Structural Biophysics Laboratory
Center for Cancer Research
National Cancer Institute

PhD positions Lund

PhD Positions in Lund

Two PhD positions are available in my group at the Division of Biophysical Chemistry in Lund. Both positions are linked to projects where magnetic relaxation dispersion (MRD) will be applied (and developed) to complex biological systems:

[1] Detection of pathological protein aggregation by field-cycled magnetic resonance imaging

[2] Molecular basis of heat and desiccation tolerance of bacterial cells and spores

For information about these two projects and the associated PhD positions, including application procedure, please go to


Application deadline is January 31, 2011.

Freitag, 17. Dezember 2010

Engineer/Physicist Post-Doc position in New Zealand

We seek a PhD graduate or equivalent to help develop a new Magnetic Resonance Imaging prototype based on a small-scale superconducting magnet. The position will suit someone with a background in MRI and NMR physics or engineering, who is interested in working in a more applied environment. The position is for two years, based in Wellington New Zealand, but the possibility exists for further employment with a partner company.

The MRI Engineer/Physicist will be responsible for a range of software and MRI pulse sequence development, hardware construction, electronic and electromagnetic engineering, application design, technical documentation and support activities around the MRI system. The work will involve aspects of the whole range of NMR and MRI from engineering to data processing. The appointee will also assist in applications development for other prototype NMR systems developed by the team.

In addition to a good understanding of NMR, applicants should have good software programming skills and a knowledge of Matlab, C++, and the Windows programming environment.

Applications, including a cv, a covering letter explaining the candidate’s interest in the job, and the names and email addresses of two referees, should be addressed to Professor Paul Callaghan, Victoria University of Wellington, New Zealand, and sent by email (paul.callaghan@vuw.ac.nz). Applications close on 31 January, 2011.

Paul T. Callaghan
Alan MacDiarmid Professor of Physical Sciences
School of Chemical and Physical Sciences
Victoria University of Wellington
New Zealand

Fax 64-4-4635237
Tel 64-4-4635945
e-mail paul.callaghan@vuw.ac.nz

Donnerstag, 16. Dezember 2010

Postdoctoral Position at Cowburn Lab

Postdoctoral Position at Cowburn Lab, Albert Einstein College of Medicine

An open postdoctoral position in structural biology is available for research on protein structure, dynamics, and function focusing on kinases and inteins.

Interested candidates should have a strong background in one or more of the following areas: multidimensional NMR, crystallography, protein expressions methods, and computer simulations of molecular structure and have completed their Ph.D.

Einstein provides a modern cross-disciplinary environment for research and education. NMR facilities include nine solution NMR spectrometers from 500 to 900 MHz equipped with cryogenic probes on site or at the New York Structural Biology Center. Extensive shared resources are available for protein production, crystallography, and high-performance computing.

The position is now available. Interested candidates should send their biographical sketch identifying three referees by email ( dc@cowburnlab.org ).

David Cowburn
Professor, Depts. of Biochemistry and of Physiology & Biophysics
Albert Einstein College of Medicine of Yeshiva University

PhD position Wellington / New Zealand

The MacDiarmid Institute for Advanced Materials and Nanotechnology at
the Victoria University of Wellington (Wellington / New Zealand) is
offering two PhD position, available from February 2011.

The research will be in the field of soft matter (complex fluids
investigated by means of Rheo‐NMR under high shear rates, application
of multidimensional NMR methods) with the focus on spatio‐temporal
fluctuations in banded‐flow, wall slip effects and start up flow of
micellar, polymeric and colloidal particles based on fast 3D NMR
velocimetry. The research to be undertaken concerns addressing
fundamental questions related to soft matter as well as the
development of the necessary NMR methodology (including hardware).

The successful applicant will be given the opportunity to work with
Dr. Petrik Galvosas and Professor Paul Callaghan in a well recognised
NMR group (http://www.macdiarmid.ac.nz/nmr/) with strong national and
international collaborations.

The PhD position is fully funded (including fees) and will enable the
successful applicants to stay in a well established academic
(http://www.victoria.ac.nz/scps/index.aspx) as well as urban
environment (http://www.wellingtonnz.com/). The scholarship provides a
non‐taxed living allowance of NZ$25,000 per annum, which is a very
comfortable living salary in Wellington, plus the PhD tuition fee for
three years. The commencement date can be as early as 1 February 2010.

Please refer to the Soft Matter and RheoNMR link at
http://www.victoria.ac.nz/scps/study/scholarships.aspx for further

Dr. Petrik Galvosas
School of Chemical and Physical Sciences
Victoria University of Wellington
PO Box 600
Wellington 6140, New Zealand
Tel: +64-4-463 6062 (office)
+64-4-463 5911 (lab)
Fax: +64-4-463 5237

Donnerstag, 9. Dezember 2010

Group Leader Positions – Bio NMR Brno

Two Group Leader Positions – Bio NMR, Central European Institute of Technology, Brno, Czech Republic

We are looking for two group leaders in the field of Bio-NMR in Structural Biology Research Program to accept the challenge of starting a world-class research group

We are recruiting two internationally established scientists to set up independent world-class research groups in the field of Bio-NMR spectroscopy in a highly inter-disciplinary setting. You will be part of the Central European Institute of Technology in Brno, Czech Republic (www.ceitec.eu). The institute will host 600 scientists and state-of-the-art equipped laboratories. The campus receives funding as a European Centre of Excellence, with a variety of international partner institutes.

Structural Biology Research Program will run core facilities for X-ray crystallography, high-end cryo electron microscopy and tomography, studies of biomolecular interactions, and high-field NMR spectroscopy. CEITEC will host also high throughput -omics facilities. Genomics and Proteomics of Plant Systems, Molecular Medicine, Molecular Veterinary Medicine, and Brain and Mind Research represent other Life Science Research Programs of CEITEC. High-field NMR Core Facility will be equipped with six 500 – 950 MHz NMR systems. Group resources include funds for post-doc positions, personnel and running costs.

You must have a PhD in a technical or scientific field and should show:
- A track record of high quality scientific publications, providing evidence of excellence in bio NMR research and applications
- Success in obtaining personal or research funding
- Experience supervising other scientists

An interest in close collaboration with local experimental groups is required. We will offer internationally competitive conditions and benefits in line with your seniority. The positions become available in 2011 and have an initial tenure of five years. We look forward to receiving your preliminary enquiries and applications addressed to Prof. Vladimír Sklenář (sklenar@chemi.muni.cz), the coordinator of the Structural Biology Research Program. The positions will be officially advertized early 2011. The onset of group operations is negotiable between 2011 and 2013.

Post Doc Toulouse

Post doctoral position announcement:

Characterisation of cholesterol – GPCR interactions by solid state NMR

As part of an Initial Training Network on the “Structural Biology of Membrane Proteins” (Marie Curie EU program SBMPs, http://www.sbmp-itn.eu), an Experienced Researcher position is available starting from 2011 in the group headed by Pr Alain Milon, “NMR and protein – membrane interactions”, Institute of Pharmacology and Structural Biology, Toulouse, France (http://www.ipbs.fr/english/teams/milon/index.htm).

G-protein coupled receptors (GPCRs) are playing a major role in signal transduction in eukaryotic cells and as such, they are of utmost pharmacological importance, being the target of about half of the major drugs currently used (1). It has been shown for several years that the lipidic environment, and in particular the sterol composition of membrane may influence the functional activation of GPCRs (2-4), and a specific cholesterol binding site has been found in the X-ray structure of the human b2 adrenergic receptor (5). Although the precise location of these cholesterol molecules bound to a GPCR are now known, much remains to be understood about their functional role and the way they actually modulate ligand binding and receptor activation. In particular the dynamics of exchange between bulk membrane cholesterol and receptor bound cholesterol remains to be determined and connected to the relevant functional time scales. Recent progresses in expression – purification of GPCRs and the availability of atomic resolution X-ray structures open the way to biophysical analyses of these interactions.

The “NMR and protein – membrane interaction group” has developed extensive expertise in the heterologous expression of GPCRs in Pichia pastoris and in E. coli (1, 6-11) and a variety opiate receptor constructs are available. It possesses a thorough expertise in analyzing sterol dynamics in model membranes by solid state NMR, using both wide line static approaches (12-17) and CP-MAS based approaches (15, 18-20). Using advanced liquid state NMR approaches and stable isotope labeling it has solved recently the 3D structure of the outer membrane protein A from Klebsiella pneumoniae, a 210 aa membrane protein domain (21, 22).

Based on this expertise, we will study cholesterol – protein interactions in lipid bilayers, micelles, and lipid cubic phases. Several membrane proteins will be used: kpOmpA, which is very stable in many environments and available in high amount with suitable stable isotope labeling, will be used to establish and develop NMR based strategies; GPCRs of the opiate family and the human b2 adrenergic receptor will be the target for understanding the functional role of cholesterol at a molecular level.

This position is opened for 12 month on the Marie Curie grant with a possibility of extension. Applicants should :

- have a PhD experience of either liquid or solid state NMR,
- have less than 5 years of research experience since the beginning of their PhD,
- not hold the french nationality,
- and not have resided in France for more than 12 months during the past 3 years.

Contact for application: Pr Alain MILON


Mittwoch, 1. Dezember 2010

Post-Doc Position at the MPI for chemical Ecology in Jena

Post-Doc Position at the MPI for chemical Ecology in Jena

A postdoctoral NMR position is available at the NMR laboratory of the Max Planck Institute for chemical Ecology, Jena (Germany) (http://www.ice.mpg.de). Our major focus is solution-state NMR of natural products (small molecules) with ecological implications. The laboratory is equipped with three Bruker spectrometers (500 MHz with a TCI cryoprobe and optional LC-SPE-NMR coupling; 500 MHz with full automation; 400 MHz optionally equippped with a microimaging probe, a HR-MAS probe, or diverse probes for NMR of liquid samples including a selective 19F probe).
Candidates should have a Ph.D. in chemistry, biochemistry, or physics. Previous NMR experience (preferentially biological liquids), interest in ecological projects and the willingness to cooperate with biologist are required.

The Max Planck Institute is an equal-opportunity employer and especially encourages women to apply. Applications from handicapped persons will be favored when all other qualifications are equal.

Please send your CV, representative publications, and recommendation addresses / letters to Bernd Schneider (schneider@ice.mpg.de).

Post-Doc fellowship in NMR Methods to Study Ionic Solids/liquids - Univ. of Aveiro/Lisbon (Portugal)

A 1-year postdoctoral position is available starting from January 2011, (extendable for additional 12 months) to study the “solid structure” of ionic liquids (ILs) and ionic solids (ISs) with relevance to the pharmaceutical industry. The research will be centred in the use of NMR techniques in tandem with molecular modelling to study the physical chemistry of molecular interactions in ILs and ISs. The project will be performed at the NMR centres at the Universities of Aveiro (solid state NMR) and Nova de Lisboa (liquids NMR).
The properties of pure ILs/ISs will be studied using liquid and solid-state NMR techniques. Multinuclear liquid-state NMR experiments and high-resolution solid-state NMR methods employing 1H-X heteronuclear experiments (X=19F, 31P, 13C) and triple resonance NMR experiments will be used to characterize ISs with low melting points (“solid ionic liquids”). These studies will be complemented with first principles calculation of NMR parameters and classical molecular dynamics simulations. In a later stage the solvation of different molecules of pharmaceutical interest in biocompatible ILs will be addressed.

The successful candidate will have the opportunity to work in a challenging environment having the possibility to be familiar with several experimental techniques (X-ray diffraction, vibrational spectroscopy) and how to use them in complement with NMR spectroscopy. The candidate will also have the opportunity to participate in a project of great relevance to the pharmaceutical industry and with impact in environmental issues. Aveiro is a very pleasant city near the seacoast, located between Porto and Lisbon with everything within walking distance.

Equipment: The candidate will have access to all equipments within the Portuguese NMR network (http://ptnmr.dq.ua.pt) ranging from 400 MHz to 800 MHz spectrometers with a variety of probes and other accessories for solids and liquids and will have access also to a shared computer cluster (http:// http://wikis.ua.pt/flamingo/). Both institutes are well equipped with 6 BRUKER AVANCE III NMR (400 to 600 MHz) spectrometers equipped with more than 20 probes. Details may be found in the aforementioned link.

Duration: 12 months extendable to 24 months, preferably from January 2011.

Candidate Profile:
- The candidate should hold a PhD in Chemistry, Physics, Physical Chemistry, Pharmaceutical Sciences, Materials Sciences or related disciplines.
- Previous experience in magnetic resonance related spectroscopy (instrumentation and theory) is necessary.
- Good informatics skills and experience with molecular modeling calculations is highly appreciated.

Salary: 1495 EUR/month (Free of taxes)

Applications will be accepted from 30th of November 2010 to 10th of January 2011.
The candidates will be informed by email about the result of the selection process.

Documents for the application:
- Cover letter;
- Detailed Curriculum Vitae and, at least, two reference contacts.

Applications should be sent by email to Dr. Luís Mafra (lmafra@ua.pt).
Alternatively, the documents should be sent to:
Dr. Luís Mafra
Departamento de Química
Universidade de Aveiro,
3810-193 Aveiro
Tel. (+351) 234 370620
(Reception of the documents by email is preferable)

Solid-state NMR Postdoc, Ames Lab

The Ames Laboratory is seeking a postdoctoral associate to conduct investigations of heterogeneous catalysts and metal hydrides by using solid state NMR spectroscopy in the research group of Dr. Marek Pruski. The successful candidate will collaborate with other PIs in the Division of Chemical and Biological Sciences and the Division of Materials Sciences and Engineering. Requirements include a Ph.D. in chemistry, physics, materials science or a related discipline. Applicants with background and experience in theoretical and experimental aspects of modern solid state NMR, including method development, are strongly encouraged to apply. Send cover letter, resume, plus the names, addresses, and telephone numbers of three references to the address given below. The position is available immediately.

Marek Pruski
Senior Scientist
Adjunct Professor of Chemistry
230 Spedding Hall
Ames Laboratory, Iowa State University
Ames, IA 50011
Phone: (515) 294-2017
Fax: (515) 294-4709
E-mail: mpruski@iastate.edu


PhD position in Strasbourg

The Membrane Biophysics and NMR team at the Chemistry Institute of the University of Strasbourg is looking for a Doctoral Student with Master or Diploma degree in Chemistry, Physical Chemistry, Biochemistry or Biophysics.

The prospective candidate will work on a project where the structural basis of highly selective interactions between a membrane-anchored polypeptide and lipids are studied using a variety of biophysical approaches including optical-, multidimensional solution- and solid-state NMR spectroscopies. Sample preparation will be performed by chemical and biochemical methods on-site and/or in collaboration with our German partners on the project.

The candidate should be open to intra- and extramural collaborations and highly motivated to acquire skills and knowledge on biophysical and /or biochemical approaches as well as peptide synthesis. She/he will work in a multidisciplinary and interdisciplinary environment with a team having access to a good number of modern instrumentation including a latest- generation Bruker 750WB solid-state NMR spectrometer (currently under installation, cf. also www.chimie.u-strasbg.fr/~rmnmc).

Please address your application including your CV, transcripts and letter of motivation a.s.a.p
to Pr. Burkhard Bechinger, University of Strasbourg / CNRS, ISIS, 8 allée Gaspard Monge, 67070 Strasbourg, email bechinge@unistra.fr. The position is financed for three years within a project funded by the French National Research Agency (ANR) and available from January 2010 on. Applications will be considered until the position has been filled.


Philippe Bertani
Laboratoire de RMN et Biophysique des Membranes
UMR 7177 LC3 Chimie Université de Strasbourg
ISIS, 8 allée G. Monge
67083 Strasbourg
Nouveau Telephone 03 68 85 51 90

Postdoctoral Position in NMR and molecular modeling at Paris Descartes University

Paris Descartes University

12 months post-doctoral position in Structural Biology NMR.

The postdoctoral position is available from February 2011 in the Paris Descartes University to characterize the interaction of new anti-cancer inhibitors with phosphorylated peptide-betaTrCP complex.

Applicants should have a Ph.D. in Biochemistry, Chemistry or related fields.

The candidate is expected to have a strong expertise in solution NMR with in-depth training in NMR receptor-ligand interaction, protein structures and dynamics, and drug-protein interactions. Familiarity with biochemistry, biophysics, and molecular biology is desirable.
Experience with molecular modelling (docking, virtual screening) and python language will be a big plus.

The candidate will join our NMR & Molecular modeling team of the laboratory of Chemical and Biochemical Pharmacology and Toxicology (UMR8601 CNRS), and be responsible for the development and structural analysis of anti-cancer by high-resolution solution NMR and molecular modeling. The main approach will be to characterize the interaction by transfer-NMR experiments (STD, WaterLOGSY, ...) and to participate in the development of AuPosSOM software (www.aupossom.com) to classify molecules according to their contact pattern with the target of interest and 2D/3D QSAR modeling.

Funding for the position is provided by the French National Agency of Research (ANR) for 1 year.

For any queries about the lab and research projects, please contact Nathalie Evrard-Todeschi by e-mail:


Dr Gildas BERTHO
Université Paris Descartes
Équipe de RMN et Modélisation Moléculaire
45 rue des Saints-Pères
75006 Paris, FRANCE
Tel : +33-(0)1-42-86-21-82
Fax : +33-(0)1-42-86-40-50
Email : gildas.bertho@parisdescartes.fr

PhD Studentship

PhD Studentship Advertisement

Hosting organizations: Institute of Food Research, University of East Anglia, and John Innes Centre

Title: Allergen thermodynamics: The effect of structure and dynamics on the susceptibility of pollen and food allergens to proteolysis
Start date: October 2011
Deadline for applications: 6 December 2010
Project details:
The goal of the project is to define how protein structure and dynamics determine the susceptibility of birch pollen allergen and its homologues to low pH proteolysis. This knowledge will provide the rational basis for development of in silico methods for predicting digestibility of proteins, a cornerstone of genetically modified organism (GMO) allergenicity risk assessment.
We propose to compare the pH-induced unfolding pathways of birch pollen allergen superfamily members (Bet v 1, Mal d 1 and Api g 1), define its impact on patterns and pathways of proteolysis, and investigate the effects of mutations on this process. Unfolding will be characterised using CD, FT-IR and NMR spectroscopy as a function of pH. Unfolding experiments will be also performed in silico using Molecular Dynamics simulations on Cray supercomputer. In silico denatured states will
be compared against NMR results, thus describing the contribution of entropic and enthalpic processes to unfolding.
The student will receive a broad training in protein structure and characterisation, spanning protein biochemistry, heterologous expression and purification, proteolysis, proteomics, low resolution spectroscopy (fluorescence, CD and FT-IR) together within silico protein structure modelling and IgE-binding studies. This will be complemented by training in protein NMR spectroscopy, covering
multidimensional spectral acquisition, processing and assignment, structure calculation, and relaxation analysis. In addition to experimental studies the student will be trained to undertake molecular dynamics techniques for protein unfoldingin silico. Transferable skills training will include
presenting to and interacting with Professor Mills Food and Health Network Allergy cluster which includes industry and academic researchers with an interest in allergy.
The candidate should be able to demonstrate an aptitude for structural biology. The particular areas include protein biochemistry, protein NMR, and structural biology.
The studentship covers UK/EU tuition fees and an enhanced rate stipend in the region of £16,600 per annum as a result of funding restrictions it is available only to UK/EU students. Overseas student should NOT apply. Successful applicants will be interviewed as part of the studentship competition.
Informal enquiries regarding the project should be directed to the project supervisors:
Clare Mills E-mail: clare.mills@bbsrc.ac.uk
Tharin Blumenschein E-mail: t.blumenschein@uea.ac.uk
How to apply:
For further information and an application form, please visit the 'How to Apply' page on our
Contact information:
Graduate Studies Office, John Innes Centre, Norwich Research Park,
Colney, Norwich, NR4 7UH, UK
Telephone: +44(0) 1603 450768
Dr. Tharin Blumenschein, Lecturer
School of Chemistry
University of East Anglia
Norwich - NR4 7TJ
United Kingdom
Phone: +44 (0)1603 59 2963

Postdoctoral position New York

Postdoctoral position: Experimental, numerical and/or theoretical
studies of spin diffusion

Brooklyn College, City University of New York, New York, USA

Inquiries are invited for a postdoctoral research position at the City
University of New York, New York. Our immediate interest is in
studying spin-diffusion, starting from small aggregates, theoretically
and experimentally, via NMR. Preference will be given to applicants
with expertise in modern solid state NMR theory and/or experiment, as
well as condensed matter theory and numerical methods. We are
particularly interested in somewhat seasoned and self-motivated
candidates. The position is available immediately.

Please send your application to Gregory Boutis
(gboutis@brooklyn.cuny.edu) or Vadim Oganesyan
(vadim.oganesyan@csi.cuny.edu) and include a cover letter as well as a
CV and the names of two to three references.

Research Fellow in experimental NMR spectroscopy

Research Fellow in experimental NMR spectroscopy

The position is for a 5-year period, starting in 2011. The research fellow works in the NMR Research Group, Department of Physics, University of Oulu, Finland (see: http://cc.oulu.fi/~nmrwww/).
The researcher must have a PhD degree in physics, chemistry or materials science, and experience in operating NMR spectrometers (for the equipment, see http://cc.oulu.fi/~nmrlab/. Purchase of new Bruker 600, 400 and 300WB systems is in progress, the latter with microimaging option) as well as in supervising graduate and post-graduate students.

Further information is available from Professor Jukka Jokisaari (Jukka.Jokisaari(at)oulu.fi and from http://www.oulu.fi/english/jobs/index.html, where also the application procedure is described.

Prof. Jukka Jokisaari
Department of Physics
( Center of Excellence in Research at the University of Oulu)
P.O.Box 3000
FIN-90014 University of Oulu
Tel. +358 8 5531308
Mobile +358 40 5956146
Fax +358 8 5531287

Donnerstag, 4. November 2010

Post-doctoral positions in Strasbourg/Illkirch

Post-doctoral program in molecular Biophysics
Biomolecular NMR group of IGBMC
Illkirch near Strasbourg (France)

The group of biomolecular NMR is seeking several hihgly motivated researcher to fullfill three post-doctoral and engineer positions in the fields of RNA/protein interactions and NMR/MS signal processing.


We are developing new tools to gain insight into protein/RNA complexes. These approches are based on specific labelling of RNA and proteins by spin labels, and combined EPR and NMR measurements.
==> A three year Post-doctoral position is available for this project. The researcher will be in charge of proteins and RNA labelling, expression and purification. Experience in molecular biology and general biophysical methods is required. Knowledge of biomolecular NMR methods will be appreciated.

Ref: Lebars et al. Nucleic Acids Res. 2010

Contact : lebars@igbmc.fr / kieffer@igbmc.fr


We are involved in the development of new acquisition and processing technics in the field of NMR and ICR Mass Spectrometry, in particular the development of multidimensional Fourier Transform Spectroscopy in NMR and FT-ICR.

In conjunction with the NMRTEC company, two one year positions are opened :

==> A one year Post-Doctoral position in signal treatment, and 1D and 2D Fourier Transform Spectroscopy (MS and NMR) (Marc-André Delsuc IGBMC)
==> A one year Engineer Position in computational development to develop a complete processing environment. (Marie-Aude Coutouly NMRTEC)

Contact : delsuc@igbmc.fr

Post-Doc position in biological solid-State NMR

The biological solid-state NMR group of Anja Böckmann at the IBCP in Lyon (www.ibcp.fr) has an opening for a post-doc.

The project is part of the Bio-NMR European joint research activity on protein structure determination by solid-state NMR, and is a collaboration which is pursued with the groups of Beat H. Meier (ETH Zurich) and Peter Güntert (University of Frankfurt). It involves production and purification of model proteins, starte-of-the-art spectroscopy, spectral analysis and structure determination. It is the aim of the project to develop a general, reliable protocol for structure determination by solid-state NMR.

For more information please contact Dr. Anja Böckmann at a.bockmann@ibcp.fr
Anja Böckmann
7, passage du Vercors
69367 Lyon Cedex 07
Tel: +33-4-72722649
Fax: +33-4-72722649
E-mail: a.bockmann@ibcp.fr

Position at Stanford

The Department of Structural Biology at Stanford University School of Medicine
continues accepting applications from qualified candidates for a tenure track
junior faculty position. Candidates must have a PhD and/ or MD degree, a
minimum of two (2) years of postdoctoral research experience along with
expertise and a commitment to future research and teaching in the broad area of
structural biology and biophysics. Application material and reference letters
must be received by November 1, 2010.

Full announcement including application requirements and procedure is available
on our website http://structuralbio.stanford.edu/recruit/. We kindly ask that
you to the attention of your colleagues this employment opportunity .

Thank you in advance for your time and consideration which is a valuable
contribution to the success of our faculty search.

Please note that Stanford University is an equal opportunity employer and is
committed to increasing the diversity of its faculty. It welcomes nominations
of and applications from women and members of minority groups, as well as
others who would bring additional dimensions to the university's research and


On behalf of the Search Committee,




A postdoctoral associate position is available in a research group, headed by Dr. Louis Madsen in the Chemistry Department at Virginia Tech in Blacksburg, VA. The position is available immediately. Candidates will be required to hold a Ph. D. in chemistry or a related field. Work will involve conceptualizing and designing new experiments to analyze advanced supramolecular and macromolecular materials using magnetic resonance techniques. Salary is competitive and full fringe benefits are included. The successful candidate will be offered a one-year contract renewable upon satisfactory performance.

To apply, go to www.jobs.vt.edu, posting number 0100850 and complete the on-line faculty application. Please attach a cover letter and CV. In the cover letter, CV, or a separately attached list, provide the names and addresses of three individuals who may serve as a reference. Applicants may be asked at a later time in the process to furnish written references. Review of applications will begin on November 2, 2010 and will continue until the position is filled.

Virginia Tech has a strong commitment to the principles of diversity, and in that spirit, seeks a broad spectrum of candidates including women, people of color, veterans, and people with disabilities. Individuals with disabilities desiring accommodations in the application process should notify Thomas Bell, 540/231-8226 or tbell@vt.edu.

PhD position Victoria University of Wellington

A PhD position is available in the MacDiarmid Institute for Advanced materials and Nanotechnology at Victoria University of Wellington.

The successful applicant will be joining an established laboratory working in the area of using Nuclear Magnetic Resonance (NMR) to measure mass transport in porous media. The project will be related to the use of novel NMR pulse sequences to measure dispersion and nonlocal dispersion using model and novel systems. There is scope in the project for a comparison with lattice-Boltzmann based simulations and/or the development of new hardware.

Laboratory facilities include 2 400MHz Bruker AVANCE Spectrometers, a 2MHz Magritek rock core analyser, a hyper-polarised xenon apparatus and various low field magnets and spectrometers.

Applicants should have graduated from a physics or chemical engineering program, preferably (but not necessarily) with a background in NMR. Full funding is available.

Supervision will be undertaken by Dr Mark Hunter and Professor Sir Paul Callaghan.

Conatct: mark.hunter@vuw.ac.nz

Working Student Magnetic Resonance Imaging

Working Student Magnetic Resonance Imaging (m/f)

Job Number:
Date Posted:
18 October 2010
Engineering/Technology - Research - Physics
GE Corporate - Global Research
Career Level:
Garching b. Munchen, Germany

About Us

GE Global Research – Europe opened in 2004 and employs approximately 150 employees from more than 20 different countries. Our scientists and technologists come from a variety of disciplines and backgrounds, including chemistry, physics, mathematics, engineering, sciences and materials research.

Located in the heart of southern Germany, Global Research – Europe sits on the Garching campus of the Technical University of Munich. This creates a unique blend for our scientists to be in a university setting, while performing research in a world-class industrial lab that is dedicated to bringing new technologies to market. The facility also operates closely with technology teams at GE businesses across the globe, ensuring effective transition of breakthrough innovations from the lab into advanced products and services. Within the R&D community, the center maintains close partnerships with numerous universities, research institutions and technology companies in Germany and abroad.

Current research at the facility focuses on automated manufacturing of composite parts, waste heat recovery for industrial and power applications, grid integration of renewable energies, molecular imaging for cancer diagnostics, high power electronics for stationary and mobile applications and advanced compressor technologies.
Role Summary/Purpose

The Imaging Technologies Lab – Europe focuses on the development of advanced clinical applications for Magnetic Resonance (MR), Ultrasound (US), and Computed Tomography (CT).
The lab closely cooperates with the respective modality labs in Niskayuna.In MR, a 3 Tesla high field system operating with multi-channel capability – receive and transmit – has been installed providing a high end platform to explore new coil technology, pulse sequences and advanced applications.
Essential Responsibilities

Your specific responsibilities will include (a subset of ) the following:

* Participate in and support an on-going research collaboration with TUM during weekly measurements with hyperpolarized 13C Metabolic MR
* Set-up new magnetic resonance components together with our systems enginee
* Design and construct RF coils for use in 13C Metabolic MR


* Strong background in engineering sciences (physicist, electrical engineering, chemistry / chemical engineering)
* Analytical and innovative thinking
* Ability to quickly become acquainted with new tasks and subjects
* Hands-on experience
* Independent working style
* good academic track record
* Excellent communication skills
* Can-do attitude
* Open, creative & flexible
* Team-work & commitment
* Fluency in English
* Currently enrolled at a university

Desired Characteristics

* basic knowledge of electrical circuits
* basic education in metal working and soldering (or completed professional education as electrician or mechanician)
* basic German

Montag, 11. Oktober 2010

Nuclear Magnetic Resonance Spectroscopist Unilever

Nuclear Magnetic Resonance Spectroscopist

Unilever is one of the world’s leading suppliers of fast moving consumer goods.
Everyday 150M times a day someone somewhere chooses a Unilever product.
Innovation is the engine of Unilever’s growth. Our future depends on our ability to
bring bigger and better innovations to the market more quickly than our
competitors. Our R&D capability is absolutely central to achieving this.

We are currently looking to recruit a nuclear magnetic resonance spectroscopist to
continue and further develop our work in the area of characterisation of biomaterials
to support our food and home and personal care businesses. The position
is within Research, a multidisciplinary group part of Unilever Research &
Development, and is based at Colworth near Bedford. Colworth is one of our six
strategic R&D sites and houses our UK NMR facility.

This particular role will primary involve the development of a variety of advanced
magnetic resonance techniques to study bio-substrates and their transport properties
behaviour to facilitate understanding and manipulation of material-body
interactions. The research will include, among others, studies on the penetration of
molecules into, and their effect on, in vitro skin. The underlying overall objective is to complement, extend and shape our research programme on human skin in vivo.

The successful candidate will work as part of a multi-disciplinary team interacting
with a wide range of scientists across multiple sites within the R&D organisation
and will also be expected to help to develop overall program directions. The
successful candidate will have a strong research background in nuclear magnetic
resonance ideally with previous experience in NMR imaging of bio-materials either
a PhD or Post Doctoral level. We are offering a one year contract.

If you are interested or would like further information please contact Dr Elisabetta
Ciampi at Unilever Discover, Colworth Science Park, Sharnbrook, Bedford MK44
1LQ, UK Tel: +44 (0)1234 222609, e-mail Elisabetta.Ciampi@unilever.com. To
apply, please email a CV including the names of two referees accompanied with a
covering letter. Closing date for applications is 07.11.2010.

Structural Biologist / Protein Engineer at Zymeworks

Zymeworks Inc. is a Canadian computational biotechnology company that is developing predictive computational technology for optimizing protein therapeutics.

Zymeworks is looking for exceptionally talented scientists to compliment our current team. We are looking for motivated individuals who are eager to showcase their talent, demonstrating the passion and drive to grow within this progressive and developing Company.

Currently, we have openings in our protein engineering department. The successful candidates will be taking part in structure guided in silico protein optimitization projects and actively participate in the development and validation of our proprietary molecular modeling and simulation software for engineering proteins.

Required Skills
· PhD or MSc in Chemistry, Biochemistry, Biophysics, Immunology, Molecular Biology, or Physics
· Strong knowledge and practical experience with the structural biology of proteins
· Experience with molecular model building, simulation and visualizing packages (AMBER, CCP4, COOT, etc.)

Skills (all or some of the following)
· Demonstrated experience in rational protein design and engineering
· Relevant experience in bioinformatics techniques
· Greater then 2 years of either industrial or academic postgraduate experience in protein biochemistry or a related field
· Experience with antibodies or other therapeutic proteins is a valuable asset
· Experience with homology modeling and docking software
· Knowledge of Linux operating system
· Experience in protein expression purification and analysis
· Experience in one or more scripting languages (Python, Tcl, etc.)
· Fluent in English (Spoken, Written, Read)

· Design and carryout internal and external protein therapeutic optimization projects
· Perform feasibility studies for proposed protein engineering projects
· Interact with collaborator’s during the experimental validation of proposed design
· Closely interact with the software development team to improve and advance the functionality of our proprietary modeling/analysis package
· Assist with the selection of other software tools to supplement our propriety simulation package
· Participate in the preparation of patents and publications

To learn more about Zymeworks Inc. and our current openings, please visit our website at www.zymeworks.com

Compensation is commensurate with experience. If you are interested in applying for this position, please email your curriculum vitae and cover letter in PDF format to careers.1243@zymeworks.com with 1243: Structural Biologist / Protein Engineer in the subject line. Due to the high volume of applicants, only those selected for interviews will be contacted.

Postdoc SSNMR

Two postdoctoral positions for experimental solid state physics are open in the Laboratory for broadband nuclear magnetic resonance at the University of Zagreb, Faculty of Science Department of Physics.

The NMR team at the Physics Department, University of Zagreb is looking for experimental post-doctoral researcher for the development of broadband NMR instrumentation and research of correlated electronic systems.

The Solid State NMR Laboratory in Zagreb has been recently established for advanced broad-band NMR experiments within the FP7 Capacities – REGPOT programme. The laboratory is equipped with two spectrometers and a 12 tesla wide-bore fully sweepable magnet of medium homogeneity (10 ppm/cm3). Cryostats cover temperature range 1.5 K – 400 K with sample space 6.25 cm in diameter.

The members of the NMR team are mostly interested in strongly correlated electronic systems (high-Tc superconductors, magnetic materials, etc.), but we are also open for other proposals suitable for investigations with the given setup.

The postdocs are expected to contribute in the research activities of the NMR group, including eventual new proposal of his/her own, but also in further optimization of experimental setup and software development.

The contracts are one year long, each. Details on the Solid State NMR Laboratory at http://nmr.phy.hr. We look for:

* Enthusiasm and interest in problems of solid state physics, and in development of scientific instrumentation.
* Good communications skills and readiness for teamwork.
* Experience in experimental NMR would be advantageous.

Applications should include a CV, references and a statement of interests.
More details about the job position by e-mail mpozek@phy.hr.

Link to Euraxess:

University of Zagreb, Faculty of Science
Department of Physics, Laboratory for Solid-state NMR

Montag, 27. September 2010


Position Title: Scholar/Scientist (CHM), Solid State Nuclear Magnetic Resonance (NMR) Spectroscopist
Appointment: 2 years renewable upon mutual agreement
Department: Chemistry and Biochemistry, Florida State University
Salary Range: $50,000 to negotiable

Qualifications: Ph.D. in chemistry with specialized training and experience in solid state NMR spectroscopy.

Knowledge of the terminology, principles and techniques of state of the art Nuclear Magnetic Resonance (NMR) spectroscopy, including solid state NMR.

Skill in the use, maintenance, and operation of modern solution and solid state NMR spectrometers.

Familiarity with NMR data processing software.

Knowledge of and experience with standard solid state pulse sequences.

Ability to implement new solid state pulse sequences.

Ability to identify NMR experiments to solve problems in solid state chemistry.

Ability to establish and maintain effective working relationships with faculty in Chemistry & Biochemistry and other departments.

Ability to communicate effectively both verbally and in writing.


Determine in consultation with faculty and students most effective NMR experiments and define experimental parameters for obtaining high resolution NMR data on a variety of solid materials; communicate results and consult with users regarding further experimentation as necessary. (25%)

Configure solid state NMR spectrometer(s), including rf-pulse sequences for optimum performance; perform routine maintenance on NMR spectrometers including regularly-scheduled cryogen maintenance. (25%)

Train and mentor graduate students and post doctoral associates in the use and applications of modern solid state NMR; supervise and monitor bi-weekly scheduling of time on instrument(s); prepare and deliver periodic lectures on emerging solid state NMR topics. (25%)

Collaborate with Faculty on ssNMR experiments. (25%)
If qualified and Interested please contact: Prof. Tyler McQuade (mcquade@chem.fsu.edu)

Timothy A. Cross
NMR Spectroscopy and Imaging Program Director
National High Magnetic Field Laboratory
1800 E. Paul Dirac Dr., Tallahassee, FL 32310-3706
Tel: 850-644-0917; Fax:: 850-644-1366; email: cross@magnet.fsu.edu

research technician

Dear colleagues,
A permanent position for a research technician (scientific associate, non-PhD level) is available immediately at Novartis in Basel. The description is attached below. Please note that this position is different and in addition to the PhD-level position which was advertised 2 weeks ago. The current position involves a broad range of biophysical methods, including NMR, SPR and crystallization, in addition to protein purification and characterization. While expertise in any of these techniques will be an advantage, training on the job will be provided for the other techniques. This should be a great opportunity for anyone with a masters or bachelors degree (or equivalent) and a strong desire to learn a broad range of biophysical methods.
If you are interested, or know anyone who is interested, please send me an email or apply online via www.novartis.com - careers - Job ID 72251BR.
Best regards
Job ID 72251BR
Position Title Scientific Associate II
Division NIBR
Business Unit Research Europe
Country Switzerland
Work Location Basel
Company/Legal Entity Switzerland Novartis Pharma AG, Basel
Functional Area Research
Job Type Full Time
Employment Type Permanent
Job Description A permanent position is open in the Structural Biology Platform of the Center for Proteomic Chemistry, NIBR (NIBR/CPC/SBP).We are looking for a motivated person to work on the purification and characterisation of protein-ligand complexes in a structural biology laboratory. This will involve the application of multiple biophysical methods such as NMR, crystallography and SPR, among others. Experience with any of these techniques is considered a significant advantage, although training can be provided on the job.
Minimum requirements Bachelors or Masters degree or equivalent. Strong background in chemistry or biochemistry. Experience in protein handling, purification and characterisation. Background in protein chemistry with protein crystallography, NMR or biophysics experience would be an advantage. Ability to work in a team and interact with colleagues in a multicultural environment. Ability to work on different projects in parallel. Desire to learn new methods and apply them to answer scientific questions.
The candidate should be prepared to implement novel approaches. Open communication, an independent and precise way of working, and excellent team work skills are important. Good knowledge of spoken and written English is required, and communication skills in German and/or French are desirable.

Biomolecular NMR Spectroscopy

Positions in Biomolecular NMR Spectroscopy at Maastricht


The Maastricht University Medical Center and the Faculty of Health, Medicine and Life Sciences (FHML) seek to fill several positions for the newly established center for NMR Structural Biology within the CARIM School for Cardiovascular Diseases and the Maastricht-Centre for Atherosclerosis Research (M-CAR). Applications are sought for a senior NMR spectroscopist, a postdoctoral associate and a technician. The senior NMR spectroscopist will essentially operate the NMR Facility under faculty directorship, and will also be encouraged to develop an independent line of research consistent with the goals of CARIM and M-CAR.

In general, successful applicants will be highly motivated individuals interested in studying the molecular basis of cardiovascular disease, as well as on the design and discovery of novel pharmaceutical agents e.g. targeting chemokine and galectin oligomers to ameliorate cardiovascular disorders.

Although NMR spectroscopy will be major focus of the Center for Structural Biology at CARIM, other biophysical methods may be employed to elucidate specific molecular mechanisms of action to better understand biological function.

The senior NMR and postdoctoral position require a PhD degree in physical sciences and experience in advanced biomolecular NMR spectroscopy of proteins and protein structure elucidation. The candidate for the technical position should have experience in NMR spectroscopy, preferably with a degree in experimental physics, biophysics, or engineering. The successful applicant for the technical position should have experience in protein expression, mutagenesis, and purification.

Salary will be commensurate with experience and the guidelines set by the Maastricht University Medical Centre.

Additional information
CARIM School for Cardiovascular Diseases
Prof. C. Weber, Prof. K. Mayo, Prof. T. Hackeng

Those interested are requested to send a cover letter describing research interests, along with a CV and list of publications, and arrange for three letters of reference to be forwarded by November 24, 2010.


The NMR and Structure Analysis unit of the Department of Organic Chemistry of Gent University (Belgium) is involved in research activities in the (bio)chemical and material sciences using NMR spectroscopy as the main investigative tool.

For this purpose, it has available a range of fully equipped Bruker NMR spectrometers, including Avance 300 and 500 MHz spectrometers, and an AVANCE–II 700 MHz instrument, housed within the unit and part of the Interuniversitary NMR Facility, jointly operated between Ghent University, the Vrije Universiteit Brussel (VUB) and Antwerp University (UA).
By spring 2011, a new 500 MHz system including a high gradient diffusion probe head will be delivered.

The duties of the successful applicant include:
Scientific research within the context of NMR research projects within the department. Scientific support and co-manager of the Interuniversity 700 MHz high field NMR facility and the new 500 MHz facility within the department. Mentoring of Master and PhD students. Contribute to the educational activities of the department (at Master level) – a minimum of at least 70% of the appointee’s time must however be spent on scientific research. The main research topic for the current position will be the further development and application of liquid state NMR techniques for the investigation of colloidal nanoparticle dispersions, including quantumdots and pigments/latexes. An idea of the type of research and our recent results can be seen at http://www.nmrstr.ugent.be/research.html .

We offer:
* The opportunity to fully participate in current research projects of the unit.
* The opportunity to play an active part in the creation and exploitation of the highest and most diversely equipped NMR facility in the region.
* A competitive salary amounting to 1800-2100 €/month (commensurate with age and experience).

To be eligible, applicants should:

* Demonstrate knowledge and practical expertise in solution NMR spectroscopy, as demonstrated by publications in international journals and/or oral communications at national or international meetings.
* Demonstrate technical knowledge in the operation of Bruker NMR equipment (hardware and software) including implementation of new and existing pulse sequences.
* Demonstrate interest for student mentoring
* Have acquired a PhD degree by the time of appointment (foreseen 1/1/2011).

The Universiteit Gent is an equal opportunity employer.
For further information contact Prof. José Martins via e-mail: Jose.Martins@UGent.be as soon as possible . Deadline for official application is October 14th --

Mittwoch, 15. September 2010

permanent protein NMR position

A permanent protein NMR position is available at Novartis in Basel, Switzerland. The description is attached below. If you are interested, please apply online via www.novartis.com - careers - Job ID 70618BR.
Kind regards
Position Title
Investigator II – Structural Biology
Job Description
Investigator II in the Structural Biology Platform (SBP) within the Center for Proteomic Chemistry (CPC) of NIBR Basel. As a member of a multidisciplinary research team you will apply NMR based techniques to study protein targets and antigen-antibody as well as protein-ligand interactions in order to facilitate the drug discovery process. Your work will include the purification of isotope labeled proteins. You will also be involved in evaluating potential new structural biology projects, coordinating the efforts of small teams towards providing structural and biophysical data to impact drug discovery projects, and representing the Structural Biology Platform in multidisciplinary/multinational project teams.
Minimum requirements

We are looking for a highly talented and motivated scientist with a PhD in biochemistry or related disciplines plus 1-3 years of postdoctoral experience in an academic or industrial setting. The ideal candidate will have extensive experience in a broad range of NMR techniques and in the area of protein purification. He/she will have a sound knowledge of biochemistry, analytics and a strong interest in the biology of human diseases. Experience in the use of additional biophysical methods to characterise protein-protein or protein-ligand interactions or crystallography would be advantageous. The candidate should be strongly committed and display a high level of creativity and passion for project work. He/she will be a member of a multi-disciplinary, multi-national team of drug discovery professionals. Excellent oral and written communication skills are required.

postdoctoral position in biomolecular NMR

A postdoctoral position in biomolecular NMR is available immediately at The
City College of New York (CCNY) located in New York City.

The selected candidate will work on a project that aims to deduce the
structural and dynamics of nick recognition and repair by DNA ligases (J. Mol.
Biol. 2010, 395, 291-308), and will join a group that includes graduate
students, postdoctoral associates and senior scientists.

The group has significant access to the NMR facilities in-house (600 MHz with a
cryoprobe) and to those at the New York Structural Biology Center (NYSBC,
500-900 all with cryoprobes). In addition, access to crystallization and
screening facilities (NYSBC) and the X4A, X4C beamlines (NSLS, Brookhaven
National Lab.) will also be available. The NYSBC is situated on the CCNY campus
a few yards from the laboratory and is the largest such center in the United

Potential applicants are expected to have extensive experience in biomolecular
NMR spectroscopy and in the expression, purification and biochemical
characterization of proteins. Applicants are requested to send their CVs and
three letters of recommendation by email to Ronnie Ghose (rghose@ghoselab.org).
A highly competitive salary and benefits package is available.

Additional information may be obtained from the group website www.ghoselab.org.

Postdoc Paris

A two-year postdoctoral position is available in the NMR group headed by Prof. G. Bodenhausen in "Laboratoire des Biomolécules" in Paris (France), under the supervision of Prof. O. Lequin.

The selected candidate will be involved in a project which aims at analyzing structure-function relationships of homeoproteins. Homeoproteins form a large class of transcription factors characterized by a conserved DNA binding domain called homeodomain. These proteins possess the striking property to be internalized within cells by direct membrane translocation processes which are not yet well understood. Homeoproteins are thus involved in original modes of cell signalling. The work of the selected candidate will mainly focus on studying the structure and interactions of homeodomains in aqueous environments, in membrane environments and in cellular environments. This project is funded by the French Agence Nationale pour la Recherche (ANR grant "PARAHP") and will be carried out in collaboration with biochemists and cell biologists (groups of A. Joliot, A. Prochiantz, L. Venance, CNRS-INSERM-Collège de France).

The candidate should have a strong expertise in NMR spectroscopy and be motivated in developing multidisciplinary research fields including liquid state NMR, solid state NMR of protein/lipid complexes, in cell NMR, and biochemistry (protein expression, membrane models, cell culture).

Contact: olivier.lequin@upmc.fr
Laboratoire des Biomolécules, UMR 7203
Université Pierre et Marie Curie – ENS – CNRS

Engineer Position

Engineer Position in the NMR Biomolecular Group in Strasbourg

A three-years engineer position is available in the NMR Biomolecular Group of the Institute of Genetics and Molecular and Cellular Biology (IGBMC) in Illkirch (near Strasbourg), France.

The research project is focused on the study of RNA/protein interactions. In particular, we propose to develop a combined Nuclear Magnetic Resonance (NMR) and spin labeling approach for the structural and dynamics studies of RNA/protein complexes. The engineer to be recruited will be in charge of proteins expression and purification, RNAs synthesis and purification, and spin labeling. Knowledge of NMR would be appreciated.

The successful candidate will have access to a fully equipped laboratory for the preparation of proteins and RNAs samples. The laboratory also holds three NMR spectrometers equipped with cryogenic probes (600 MHz and 700 MHz) and with a TXI probe (500 MHz).

Candidates must hold a Master or have a two-years significant experience in Molecular Biology. Applications should include CV, statement of interest and references.

Starting date: 2010-12-01

Contact informations:
Pr Bruno KIEFFER, kieffer@igbmc.fr and Dr Isabelle Lebars, lebars@igbmc.fr
IGBMC Biomolecular NMR group
1 rue Laurent Fries
BP 10142
67404 Illkirch CEDEX
Tel.: +33 (0) 3 68 85 44 07 / +33 (0) 3 68 85 47 22

Mittwoch, 1. September 2010

PhD studentship, Massey University, New Zealand

PhD studentship, Massey University, New Zealand

A PhD studentship is available to apply state-of-the-art NMR techniques, along with other biophysical approaches and computational analyses, to protein and RNA structure and dynamics. This project is a collaboration with the University of Sydney, where complementary Small Angle X-ray Scattering (SAXS) studies will be performed, and with the New York Structural Biology Center, which houses spectrometers up to 900 MHz. The Massey University Centre for Structural Biology houses a 700 MHz Bruker Avance NMR spectrometer with cryoprobe in addition to 500, 400 and 200 MHz spectrometers. Support is via a grant from the Royal Society of New Zealand.

The PhD fellowship carries a tax exempt stipend of NZD 23,000 per anna. There is no teaching requirement, and all student tuition and fees are covered by the grant. Students with exceptional undergraduate marks may be eligible for a University Scholarship which provides an increased stipend level.

The nominal closing date is 30 September 2010, however applications will be reviewed as they are received, and will be accepted until the position is filled.

Interested parties should email a cover letter, c.v. and contact information for three referees to Associate Professor Steven Pascal.

See http://ifs.massey.ac.nz/people/staff.php?personID=56 for email address and further information.
Steven M. Pascal
Associate Professor and
Director of BioNMR Research
Centre for Structural Biology
Institute of Fundamental Sciences
Massey University
Palmerston North, New Zealand
voice: 646-356-9099 ext 3558
fax: 646-350-5682

Montag, 30. August 2010

Postdoctoral Position at St. Jude Children’s Research Hospital

Postdoctoral Position at St. Jude Children’s Research Hospital

Title: Structural Biology: Tanja Mittag, PhD

Requisition Number: 6447

A postdoctoral position is available immediately for a highly motivated individual interested in studying the molecular basis of dynamic protein complexes in the ubiquitination pathway and cell cycle control in the laboratory of Tanja Mittag at St. Jude Children's Research Hospital in Memphis, TN USA. 70% of cancer-related proteins contain long disordered regions that convey important roles in cells, particularly in mediating interactions with other macromolecules in signal transduction. Disordered protein regions can execute their functions in the absence of a well-defined structure. It is becoming increasingly clear that even their complexes may remain largely disordered, allowing for unusual properties such as signal integration, graded and ultrasensitive responses. We will use NMR spectroscopy and other biophysical methods to elucidate molecular mechanisms of these protein interactions to understand their biological functions and the benefits of protein disorder.

The position is an ideal opportunity for either a candidate with experience in NMR spectroscopy to complement their training by learning other biochemical and biophysical techniques or for a biochemist/biophysicist interested in advanced protein NMR spectroscopy techniques. The fellow would benefit both from the excellent departmental facilities and from the collaborative St. Jude community. Candidates should have (or expect) a Ph.D. and/or M.D. and should have experience in protein expression, purification, and/or NMR spectroscopy.

Please apply online ( https://hospital.stjude.org/apps/apo/index.jsp ) and send a CV with list of publications, a brief letter of research interests and goals and arrange for three reference letters to be forwarded to

Tanja Mittag, PhD
Assistant Member
Department of Structural Biology
St. Jude Children's Research Hospital
262 Danny Thomas Place, MS 311
Memphis, TN 38105
Email: tanja.mittag@stjude.org

Post-doc position opening in Orleans, France

We are currently looking for a post-doc candidate in the context of an international US-French collaborative project focusing on the local structures around active heteroatoms in boro- and alumino-silicate materials for catalysis. It is a three-year project that started in January 2010 and is co-funded by the French Agence Nationale pour la recherche (ANR) and the US National Science Fundation (NSF).

The work of the selected candidate will mainly focus on determining the molecular structures of alumino- and boro-silicate materials that cannot be accessed from XRD analyses. Therefore, he/she will combine semi-empirical and/or ab initio molecular dynamics and density functional theory (DFT) calculations with experimental solid-state nuclear magnetic resonance (NMR) data. He/she will have to develop semi-automatic protocols that integrate the large range of information that can be obtained using NMR spectroscopy, including chemical shifts, quadrupolar interactions, dipolar and scalar couplings and their calculation by DFT with quantum mechanical molecular modeling and structure-determination approaches to propose, solve, and refine the structure of layered and three-dimensional silicate materials and their B- or Al-incorporated analogs. He/she will explore the possibilities for modeling the local structural order and disorder around heteroatom sites and analyze their consistency with multidimensional correlated NMR data. Resulting interpretations of the local ordering and/or disordering at and near heteroatom sites will ultimately be correlated with the macroscopic properties of these materials to propose predictive models of their influence on catalytic properties of boro- and alumino-silicate materials.

The duration of the contract will be 18 months, with a salary of 1800-2500 euros/months depending on previous experience.

We are looking for a candidate with a PhD in the field of chemistry or physics with strong backgrounds in molecular modeling and materials chemistry. Practical experience with solid-state NMR spectroscopy will be considered a plus, but is not mandatory for the position.

The group (http://www.cemhti.cnrs-orleans.fr/Poles/?idtheme=1) of Dominique Massiot (http://www.cemhti.cnrs-orleans.fr/Contact/PeopleFile.aspx?id=27) has a widely-recognized expertise in solid-state NMR of inorganic and hybrid organic-inorganic materials, and we are currently integrating increasing amounts of molecular modeling dedicated to the prediction of NMR parameters for the interpretation of experimental data. We have access and practical experience with codes such as CASTEP, Gaussian, and Quantum Espresso, with privileged access to local supercomputers.

Orléans, is a very nice city in the center of France, surrounded by beautiful forests, and located just one hour by train from the very center of Paris.

Please send a CV, motivation letter, and list of referees to:
Dr. Sylvian CADARS
1D, Av. de la Recherche Scientifique
45071 Orléans Cedex 2, France
Fax: +33 (0) 2 38 63 81 03
Tel: +33 (0) 2 38 25 55 04
email: sylvian.cadars@cnrs-orleans.fr

Montag, 23. August 2010

NMR Scientist at the Environmental NMR Centre

NMR Scientist at the Environmental NMR Centre, University of Toronto

The Environmental NMR Centre and the Department of Physical and Environmental
Sciences at the University of Toronto Scarborough are seeking a Senior NMR
Research Associate to oversee the daily operation, training, and management of
the Environmental NMR Centre. The position has a very large research and
development component and the candidate is expected to work closely in and with
the facilities Directors to maintain the centre at the cutting-edge of
Environmental NMR globally and be central to pioneering new developments in NMR
in general.

The Environmental NMR Centre currently houses two unique, Bruker BioSpin NMR
systems. The first is a fully hyphenated 2D-HPLC-SPE-NMR-MS, and is novel both
in Canada and Environmental Research in general. The second system has
capabilities to perform in situ multiphase NMR analyses of heterogeneous
samples that contain solid, gel and solution phase samples, the hardware is
globally unique and being co-developed directly with Bruker BioSpin. The Centre
focuses on the development and application of NMR techniques to study a range
of environmental problems. The current topics of research include:
environmental metabolomics, LC-SPE-NMR-MS applications to complex environmental
mixtures, in vivo NMR spectroscopy imaging, hyperpolarization, DNP, development
of multiphase NMR methods (solids, HR-MAS, solutions NMR as a single
technique). In addition, the Centre focuses on the development and application
of novel NMR approaches to complex systems (including soils, ocean sediments,
atmospheric deposits (particles, rain, snow, glacial ice), cells, tissues,
small organisms and other environmental matrices) to better understand
structure and environmental reactivity.

After an initial probationary period, this will be a continuing full-time

The NMR scientist will report to the Chair of the Department and work closely
with the Director and Associate Director of the Environmental NMR Centre. The
research associate will be responsible for instrument maintenance, training of
graduate students/postdoctoral fellows/visiting scientists, assist in writing
grant applications to upgrade the centre and co-publication of research with
the facility's principal investigators and collaborators. The candidate will
also be expected to lead research projects publishing both as a primary and
secondary author. The successful candidate will take an active role in all
aspects of the research of the NMR Centre and will strive to ensure that he/she
becomes recognized as a leader in the field of Environmental NMR spectroscopy.

The candidate will also be involved in undergraduate thesis supervision in the
Department's chemistry program and will be encouraged to apply to instruct one
course in the undergraduate chemistry program on a yearly basis. The candidate
will also oversee the operation/maintenance of a teaching/research Departmental
NMR system (Bruker BioSpin 500MHz Avance) and ensure that faculty and students
can acquire high quality data required for the teaching and research programs.
These duties will include the set up of new experiments, training of
students/faculty, maintenance and calibration. Candidates should note that the
departmental NMR system is fully automated (BACS) with a single automatic
tuning and matching probe (ATM) and that the department has only a small number
of users, once running smoothly should require minimal intervention on a daily

Applicants must have a Ph.D. in Chemistry or related discipline with a very
strong background in NMR spectroscopy and a drive/passion for the development
of NMR spectroscopy. In exceptional circumstances, an established leader in the
field with a MSc degree but more than 10 years of experience may be considered.
In addition, experience with metabolomics, chromatography, mass spectrometry
and working with complex biological and/or environmental systems are a strong
assets. Experience with pulse programming, custom processing of NMR data
(MATLAB, ACD, etc.) and programming/webpage design is also beneficial.
Experience with Bruker instruments is very important and the ideal candidate
will have experience in (or enthusiastic to learn) all areas of NMR including
solutions, HR-MAS, solids and imaging.

Salary will be commensurate with the candidate's qualifications and experience.

Applicants should send a cover letter, curriculum vitae, a statement of
research, a statement of teaching and three letters of reference to:

Rose Jones (Assistant to the Chair)
NMR Scientist Search Committee
Department of Physical & Environmental Sciences
University of Toronto Scarborough
1265 Military Trial
Toronto, Ontario M1C 1A4

Email submissions should be sent to: rjones@utsc.utoronto.ca

Unfortunately, applications that are not accompanied by at least three
references cannot be considered.

We will start reviewing applications beginning September 13, 2010, although the
search will remain open until the position is filled.

The University of Toronto is strongly committed to diversity within its
community and especially welcomes applications from visible minority group
members, women, Aboriginal persons, persons with disabilities, members of
sexual minority groups, and others who may contribute to the further
diversification of ideas.

All qualified candidates are encouraged to apply; however, Canadians and
permanent residents will be given priority.

Faculty Position in High Field Neuro MRI

Faculty Position in High Field Neuro MRI
The Radiological Sciences Laboratory in the Department of Radiology at Stanford University is searching for a full-time Assistant or Associate Professor in the Non-tenure Line (Research). The major criterion for appointment for faculty in the Non-tenure Line (Research) is evidence of high-level performance as a researcher for whose special knowledge a programmatic need exists.
The broad research program to be served by this position is the high field MRI program at Stanford as it intersects with the neuroscience program at Stanford. We are specifically interested in candidates whose skill set could range from a technology development focus to an application focus, but in all cases, the candidate will be expected to combine the areas of high field MRI and neuroscience. It is expected that the successful candidate will possess PhD degree or combined PhD/MD. The rough estimate for the proposed distribution of efforts is approximately 80% research and 20% teaching.
The Richard M. Lucas Imaging Center at Stanford houses a 7T whole body MRI system which forms the centerpiece of the high field program at Stanford. This system will be upgraded to a next generation GE MR950 platform with fully independent 8-channel parallel transmit technology, in 2011. This advanced technology will co-exist with latest generation research-dedicated GE 3T and 1.5T scanners within the same Lucas center, as well as a 7T GE MR901 animal MRI housed within the small animal imaging facility at Stanford. Stanford has a strong collaborative research relationship with the manufacturer of all of these systems (GE).
Stanford University is an equal opportunity employer and is committed to increasing the diversity of its faculty. It welcomes nominations of and applications from women and members of minority groups, as well as others who would bring additional dimensions to the university's research, teaching and clinical missions.
Please send curriculum vitae, a brief statement describing your clinical, teaching and research activities and interests, and names of three references to:
Brian Rutt, Ph.D. Professor of Radiology and Search Committee Chair
brutt@stanford.edu 1201 Welch Road
Stanford, CA 94305-5488 USA

Freitag, 20. August 2010

Postdoc Toronto

A postdoctoral position is available for a Canadian Institutes of Health
Research funded project in the laboratory of Professor Voula Kanelis at the
University of Toronto Mississauga (UTM). The successful candidate will
investigate the nucleotide binding domains (NBDs) of the sulfonyl urea
receptors (SURs) using biophysical approaches, including NMR spectroscopy. SUR
proteins are ABC transporters that form the regulatory subunits of
ATP-sensitive potassium (KATP) channels. We are studying the effects of
disease-causing mutations in the SUR NBDs on their stability, structure, and
interactions with other regions in the SURs and in KATP channels. A Ph.D. in
biochemistry or a related discipline is required. Candidates should have
experience with protein expression and purification and protein NMR

Located 30 km west of downtown Toronto, The University of Toronto Mississauga
(www.utm.utoronto.ca) is a campus of the University of Toronto
(www.utoronto.ca), the largest research University in Canada. UTM provides all
of the advantages of research at the University of Toronto, while additionally
providing a smaller, friendly campus environment in a beautiful natural setting
by the Credit river.

Our newly renovated and well-equipped laboratory contains all the equipment
necessary for protein biochemistry and fluorescence spectroscopy. Other
equipment (CD spectrophotometer, isothermal titration calorimeter, differential
scanning calorimeter) is available in the Center for Applied Bioscience and
Biotechnology at the University of Toronto Mississauga. NMR experiments will be
performed primarily on a Varian 600 MHz spectrometer equipped with a cryoprobe
at UTM. We also have access to high-field spectrometers located at the
University of Toronto NMR facility.

Interested applicants should submit their CV, contact information for three
references, and a description of previous research experience to Voula Kanelis
Voula Kanelis
Assistant Professor
Department of Chemical and Physical Sciences
University of Toronto Mississauga
3359 Mississauga Road North
South Building, Room 4042
Mississauga, ON, L5L 1C6
PHONE: 905-569-4542
FAX: 905-828-5425
E-MAIL: voula.kanelis@utoronto.ca

Postdoctoral Position "Solution Dynamics of Protein Kinases" in New York

A postdoctoral position to study the solution dynamics and structure
of protein kinases is available on a NIH funded project (REF#:
HS-R-6453-10-08-S). Our group is interested in how static and dynamic
changes of protein structure affect the activity of protein kinases.
We combine X-ray crystallography, NMR and ligand binding kinetics with
collaborative molecular dynamic studies (See e.g. ref 1 and 2). Our
research group is located at Stony Brook University in a highly
interactive environment with the New York Structural Biology Center
and Brookhaven National Laboratory. Varian and Bruker NMR instruments
with 500-700 MHz field strenghts are available on site. As a member of
the New York Structural Biology Center, we have access to 800 MHz and
900 MHz instruments as well as a access to a large pool of NMR
expertise. The location of Stony Brook University within public
transport commuting distance to New York City and the north shore of
Long Island provide a convenient work-life balance and a family
friendly environment.
Interested candidates with a strong background in protein NMR should
email their CV and the names of three references to Markus Seeliger

1.) Shan, Y., Seeliger, M.A., et al. A conserved
protonation-dependent switch controls drug binding in the Abl kinase.
Proc Natl Acad Sci U S A, 2009. 106(1): p. 139-44.

2.) Seeliger, M.A., et al., Equally potent inhibition of c-Src and Abl
by compounds that recognize inactive kinase conformations. Cancer Res,
2009. 69(6): p. 2384-92.

Markus Seelige
Assistant Professor
Department of Pharmacological Sciences
Stony Brook University Medical School, BST 7-125
Stony Brook, NY 11794-8651
phone: (631) 444-3558 fax: (631) 444-9749

1 Postdoc and 1 PhD position MPI Göttingen

1 Postdoc and 1 PhD position in Computational NMR at the Max-Planck-Institute for Biophysical Chemistry

are available. The aim of the project is to further develop the PALES method (Zweckstetter, Nature Protocols 2008) to predict residual dipolar couplings from a given 3D structure. The project requires experience in C programming. NMR and/or biochemical knowledge is advantageous.

An excellent environment is available for training in the area of biomolecular NMR spectroscopy. The Max Planck Institute for Biophysical Chemistry, Göttingen, is one of the top research institutes in Germany. The NMR center at the MPI for Biophysical Chemistry houses numerous, state-of-the-art NMR spectrometers from 400 to 900 MHz for both solution and solid-state NMR spectroscopy. In addition, a fully equipped laboratory for production of recombinant proteins is available.

The Ph.D. position (BAT IIa/2) is limited for two years but can be extended for an additional year. The postdoc position (BAT IIa) is available for three years.

Interested applicants should send a CV and contact information for two references to:

Prof. Dr. Markus Zweckstetter
Max Planck Institute for Biophysical Chemistry
Am Fassberg 11, D-37077 Göttingen
Tel.: ++49-551-201-2220
Fax: ++49-551-201-2202
Email: mzwecks@gwdg.de

Freitag, 30. Juli 2010

Academic Positions University of Kent, UK

The School of Biosciences wishes to appoint five Faculty members at any level (Lecturer/Senior Lecturer/Reader/Professor) including two new members of the Protein Science Research Group within the areas of:

Structural Biology Ref: STM0154
Chemical Biology/Enzymology Ref: STM0155

In addition to integrating with current strengths in protein science, individuals would also be encouraged to engage with the Centre for Molecular Processing (see above). Following a recent £0.5 M award to upgrade our NMR facility by the Wellcome Trust and we are particularly interested in research scientists who can contribute to the use and development of this facility. The upgrade will provide a new console and cryogenic probe for our existing 600 MHz NMR spectrometer.

More details can be found at the University of Kent website and inserting references: STM0154 or STM0155 as above.

Closing date for applications is Monday 6 September, 2010.

Informal enquiries can be made to Dr. Mark Howard
Dr. Mark J. Howard CSci CChem MRSC
Senior Lecturer in Biomolecular NMR Spectroscopy
School of Biosciences
University of Kent
Canterbury, Kent, CT2 7NJ, UK.

Tel No: 01227 824730 (office) or 827117 (NMR)

Mittwoch, 21. Juli 2010

Faculty positions (including NMR) in Okinawa

Faculty positions (including NMR) in Okinawa, Japan

The Okinawa Institute of Science and Technology (OIST http://www.oist.jp)
invites applications for new faculty positions as it enters a period of growth
in preparation for transition to an international graduate university in 2012.
Approximately 15 faculty positions will be filled during this search. OIST
provides a world-class research environment in newly completed facilities in an
area of distinctive culture, unique ecology, and outstanding natural beauty.

Successful candidates will be given the opportunity to excel in their chosen
area of research, and will be expected to contribute to graduate teaching,
research supervision and other academic activities. Applicants should have a
PhD or equivalent degree, and demonstrate excellence in research.

The initial appointment will be as Principal Investigator (PI) or Independent
New Investigator (INI) for a term of five years. When the transition to a
graduate university is completed in 2012, it is planned that PI and INI
positions will change to a tenure track system with Assistant Professors,
Associate Professors, and Professors. Some appointments will be made on a joint
or part-time basis. Substantial internal funding will be provided to support
the faculty members research, based on a 5-year research plan, which is
renewable after scientific review.

This search is targeted broadly. The non-departmental structure of OIST and
orientation toward interdisciplinary research permits flexibility in appointing
applicants who are able to introduce new research areas or enhance existing
areas. Established research areas include genomics, developmental biology,
mathematical and computational biology, molecular and cell sciences and
neuroscience. New research areas include structural biology, biological
physics, biological chemistry, marine sciences, ecology and evolutionary
biology, and microbial and plant genetics. Applicants with exceptional skills
in the development of novel instrumentation, particularly instruments that will
further revolutionize imaging of bio- and nanosystems, are also encouraged to

At a time when worldwide support for research is increasingly risk-averse, and
grant funding places an ever-growing burden on faculty, OIST promotes
innovative research in a highly facilitating and supportive environment. This
is achievable because OIST has internal research funding, offers outstanding
central research facilities, and consults faculty on the design of new
laboratory space. Central research facilities at OIST include core facilities
for genomics, rodent vivarium, radioisotope use, electron microscopy, and
supercomputing facilities.

OIST is committed to being international with more than 50% of faculty and
researchers from outside Japan. The official language of OIST is English. OIST
is an equal opportunity, affirmative action employer and encourages
applications from women. More details regarding the aims of the search and
advantages of working at OIST are available in the Information for Applicants
in the application package that is downloadable from the website
Applications should be submitted in accordance with the instructions in the
application package. Applications for the current search close 31, July 2010.
Interviews will take place in late August/September, with a view to making
appointments early in 2011.

Post-doctoral position Schlumberger

Post-doctoral position – NMR Spectroscopist.

High tech industrial research laboratory in Cambridge, Massachusetts looking for an analytical chemist with a broad background in NMR spectroscopy. Research will focus on developing and applying methods in solid-state NMR spectroscopy to characterize the composition of complex mixtures such as high molecular weight fossil fuels, heavy oils, and kerogen. These materials are important to the development of unconventional hydrocarbon energy resources. This project represents part of a larger effort to characterize these materials by various spectroscopies as well as to understand relationships between composition and the behavior of these materials during production. Previous experience with statistics and/or fossil fuels is a plus. Please send resume and letter of interest to SDRJobs@slb.com.

Company Description
Schlumberger is recognized as a world leader in oilfield exploration and production technology, with operations in over 100 countries. Schlumberger personnel are recruited in every country in which we operate and a wide mix of nationalities operates in each product line and business segment. Schlumberger does not have a 'nationality', which describes its culture, but operates in a truly global fashion throughout the world. Schlumberger-Doll Research is a center for applied research in electromagnetics, geoacoustics, applied mathematics, measurement while drilling, petrophysics, geological modeling, and reservoir characterization (see Schlumberger Oilfield Research: www.slb.com/research). Schlumberger-Doll Research is an Equal Employment Opportunity Employer M/F/D/V.

Postdoctoral Position Cornell University

Postdoctoral Position
Magnetic Resonance Force Microscopy
Available Immediately

John Marohn (jam99@cornell.edu)
Dept. of Chemistry and Chemical Biology
Cornell University
Ithaca, NY 14853-1301 USA

A postdoctoral research position is available immediately in the Department of Chemistry and Chemical Biology at Cornell University. The goals of the project are to detect and image individual nitroxide electron spin labels affixed to biomolecules and to detect and image small numbers of nuclear spins using magnetic-tipped cantilevers. The work will harness recent breakthroughs in the mechanical detection of magnetic resonance from electron spins [1,2] and nuclear spins [3], and will make particular use of attonewton-sensitivity cantilevers fabricated by our team at the Cornell Nanoscale Science and Technology (nanofabrication) facility [4].

The candidate should have an interest in magnetic resonance and experience in the design and construction of scanned probe microscope (or related) instrumentation, ideally involving high vacuum and cryogenic temperatures. The ideal candidate would also have experience in nanopositioning equipment, digital electronics, lasers, fiber optics, microwave electronics, and radiofrequency electronics.

Interested candidates should send a curriculum vitae to John Marohn at jam99@cornell.edu. The vitae should include the candidate's publication list, the names of three references, a summary of research skills, and a statement of his/her research interests and plans. Please include the phrase “Cornell MRFM Postdoc” in the title of your email.


[1] Moore, E. W.; Lee, S.-G.; Hickman, S. A.; Wright, S. J.; Harrell, L. E.; Borbat, P. P.; Freed, J. H. & Marohn, J. A. Scanned-probe detection of electron spin resonance from a nitroxide spin probe. Proc. Natl. Acad. Sci. U.S.A., 2009, 106, 22251 - 22256. doi = 10.1073/pnas.0908120106.

[2] Moore, E. W.; Lee, S.-G. ; Hickman, S. A.; Harrell, L. E. & Marohn, J. A. Evading surface- and detector frequency noise in harmonic oscillator measurements of force gradients. Appl. Phys. Lett. (in press), 2010.

[3] Degen, C. L.; Poggio, M.; Mamin, H. J.; Rettner, C. T. & Rugar, D. Nanoscale magnetic resonance imaging. Proc. Natl. Acad. Sci. U.S.A., 2009, 106, 1313 - 1317. doi = 10.1073/pnas.0812068106.

[4] See http://www.cnf.cornell.edu