Freitag, 30. Juli 2010

Academic Positions University of Kent, UK

The School of Biosciences wishes to appoint five Faculty members at any level (Lecturer/Senior Lecturer/Reader/Professor) including two new members of the Protein Science Research Group within the areas of:

Structural Biology Ref: STM0154
and
Chemical Biology/Enzymology Ref: STM0155

In addition to integrating with current strengths in protein science, individuals would also be encouraged to engage with the Centre for Molecular Processing (see above). Following a recent £0.5 M award to upgrade our NMR facility by the Wellcome Trust and we are particularly interested in research scientists who can contribute to the use and development of this facility. The upgrade will provide a new console and cryogenic probe for our existing 600 MHz NMR spectrometer.

More details can be found at the University of Kent website and inserting references: STM0154 or STM0155 as above.

Closing date for applications is Monday 6 September, 2010.

Informal enquiries can be made to Dr. Mark Howard
================================================
Dr. Mark J. Howard CSci CChem MRSC
Senior Lecturer in Biomolecular NMR Spectroscopy
School of Biosciences
University of Kent
Canterbury, Kent, CT2 7NJ, UK.

Tel No: 01227 824730 (office) or 827117 (NMR)
================================================

Mittwoch, 21. Juli 2010

Faculty positions (including NMR) in Okinawa

Faculty positions (including NMR) in Okinawa, Japan
http://www.oist.jp/en/newsevent/careers/542-faculty-positions.html

The Okinawa Institute of Science and Technology (OIST http://www.oist.jp)
invites applications for new faculty positions as it enters a period of growth
in preparation for transition to an international graduate university in 2012.
Approximately 15 faculty positions will be filled during this search. OIST
provides a world-class research environment in newly completed facilities in an
area of distinctive culture, unique ecology, and outstanding natural beauty.

Successful candidates will be given the opportunity to excel in their chosen
area of research, and will be expected to contribute to graduate teaching,
research supervision and other academic activities. Applicants should have a
PhD or equivalent degree, and demonstrate excellence in research.

The initial appointment will be as Principal Investigator (PI) or Independent
New Investigator (INI) for a term of five years. When the transition to a
graduate university is completed in 2012, it is planned that PI and INI
positions will change to a tenure track system with Assistant Professors,
Associate Professors, and Professors. Some appointments will be made on a joint
or part-time basis. Substantial internal funding will be provided to support
the faculty members research, based on a 5-year research plan, which is
renewable after scientific review.

This search is targeted broadly. The non-departmental structure of OIST and
orientation toward interdisciplinary research permits flexibility in appointing
applicants who are able to introduce new research areas or enhance existing
areas. Established research areas include genomics, developmental biology,
mathematical and computational biology, molecular and cell sciences and
neuroscience. New research areas include structural biology, biological
physics, biological chemistry, marine sciences, ecology and evolutionary
biology, and microbial and plant genetics. Applicants with exceptional skills
in the development of novel instrumentation, particularly instruments that will
further revolutionize imaging of bio- and nanosystems, are also encouraged to
apply.

At a time when worldwide support for research is increasingly risk-averse, and
grant funding places an ever-growing burden on faculty, OIST promotes
innovative research in a highly facilitating and supportive environment. This
is achievable because OIST has internal research funding, offers outstanding
central research facilities, and consults faculty on the design of new
laboratory space. Central research facilities at OIST include core facilities
for genomics, rodent vivarium, radioisotope use, electron microscopy, and
supercomputing facilities.

OIST is committed to being international with more than 50% of faculty and
researchers from outside Japan. The official language of OIST is English. OIST
is an equal opportunity, affirmative action employer and encourages
applications from women. More details regarding the aims of the search and
advantages of working at OIST are available in the Information for Applicants
in the application package that is downloadable from the website
(http://www.oist.jp/en/newsevent/careers/542-faculty-positions.html).
Applications should be submitted in accordance with the instructions in the
application package. Applications for the current search close 31, July 2010.
Interviews will take place in late August/September, with a view to making
appointments early in 2011.

Post-doctoral position Schlumberger

Post-doctoral position – NMR Spectroscopist.

High tech industrial research laboratory in Cambridge, Massachusetts looking for an analytical chemist with a broad background in NMR spectroscopy. Research will focus on developing and applying methods in solid-state NMR spectroscopy to characterize the composition of complex mixtures such as high molecular weight fossil fuels, heavy oils, and kerogen. These materials are important to the development of unconventional hydrocarbon energy resources. This project represents part of a larger effort to characterize these materials by various spectroscopies as well as to understand relationships between composition and the behavior of these materials during production. Previous experience with statistics and/or fossil fuels is a plus. Please send resume and letter of interest to SDRJobs@slb.com.

Company Description
Schlumberger is recognized as a world leader in oilfield exploration and production technology, with operations in over 100 countries. Schlumberger personnel are recruited in every country in which we operate and a wide mix of nationalities operates in each product line and business segment. Schlumberger does not have a 'nationality', which describes its culture, but operates in a truly global fashion throughout the world. Schlumberger-Doll Research is a center for applied research in electromagnetics, geoacoustics, applied mathematics, measurement while drilling, petrophysics, geological modeling, and reservoir characterization (see Schlumberger Oilfield Research: www.slb.com/research). Schlumberger-Doll Research is an Equal Employment Opportunity Employer M/F/D/V.

Postdoctoral Position Cornell University

Postdoctoral Position
Magnetic Resonance Force Microscopy
Available Immediately

John Marohn (jam99@cornell.edu)
Dept. of Chemistry and Chemical Biology
Cornell University
Ithaca, NY 14853-1301 USA
http://www.marohn.chem.cornell.edu/

A postdoctoral research position is available immediately in the Department of Chemistry and Chemical Biology at Cornell University. The goals of the project are to detect and image individual nitroxide electron spin labels affixed to biomolecules and to detect and image small numbers of nuclear spins using magnetic-tipped cantilevers. The work will harness recent breakthroughs in the mechanical detection of magnetic resonance from electron spins [1,2] and nuclear spins [3], and will make particular use of attonewton-sensitivity cantilevers fabricated by our team at the Cornell Nanoscale Science and Technology (nanofabrication) facility [4].

The candidate should have an interest in magnetic resonance and experience in the design and construction of scanned probe microscope (or related) instrumentation, ideally involving high vacuum and cryogenic temperatures. The ideal candidate would also have experience in nanopositioning equipment, digital electronics, lasers, fiber optics, microwave electronics, and radiofrequency electronics.

Interested candidates should send a curriculum vitae to John Marohn at jam99@cornell.edu. The vitae should include the candidate's publication list, the names of three references, a summary of research skills, and a statement of his/her research interests and plans. Please include the phrase “Cornell MRFM Postdoc” in the title of your email.

References:

[1] Moore, E. W.; Lee, S.-G.; Hickman, S. A.; Wright, S. J.; Harrell, L. E.; Borbat, P. P.; Freed, J. H. & Marohn, J. A. Scanned-probe detection of electron spin resonance from a nitroxide spin probe. Proc. Natl. Acad. Sci. U.S.A., 2009, 106, 22251 - 22256. doi = 10.1073/pnas.0908120106.

[2] Moore, E. W.; Lee, S.-G. ; Hickman, S. A.; Harrell, L. E. & Marohn, J. A. Evading surface- and detector frequency noise in harmonic oscillator measurements of force gradients. Appl. Phys. Lett. (in press), 2010.

[3] Degen, C. L.; Poggio, M.; Mamin, H. J.; Rettner, C. T. & Rugar, D. Nanoscale magnetic resonance imaging. Proc. Natl. Acad. Sci. U.S.A., 2009, 106, 1313 - 1317. doi = 10.1073/pnas.0812068106.

[4] See http://www.cnf.cornell.edu

Dienstag, 20. Juli 2010

postdoctoral position in macromolecular NMR

There is an opening for a postdoctoral position in macromolecular NMR
and structural biology at the Structural Biophysics Laboratory, National
Cancer Institute, Frederick, MD.

A highly motivated individual is sought to conduct studies in NMR, dynamics,
and integrated structural and functional understanding of proteins and complexes
in the ubiquitination pathway. For an example of the type of work please see
Mol. Cell 34(6):674 [2009]. Individuals interested in spectroscopy, new methods, and/or
biological applications with a commitment to a research career are encouraged to apply.

The position is fully funded and the initial appointment can be extended. Resources
include a wide range of biophysical equipment and NMR spectrometers.

For further information, please contact R. Andrew Byrd via email at byrdra@mail.nih.gov

===============================================
R. Andrew Byrd 301-846-1407
Dir., Molecular Discovery Program
Chief, Structural Biophysics Laboratory FAX 301-846-6231
Macromolecular NMR byrdra@mail.nih.gov
http://ccr.cancer.gov/resources/sbl/

Center for Cancer Research
National Cancer Institute-Frederick
P.O. Box B, Bldg. 538
Frederick, MD 21702-1201
===============================================

Project leader positions at IECB Bordeaux 2010

Project leader positions at IECB Bordeaux 2010

The European Institute of Chemistry and Biology, Institut Européen de Chimie
et Biologie (IECB) is a research institute sponsored by the University of
Bordeaux, CNRS and INSERM. It is located on the University of Bordeaux campus
in the Southwest of France. The Institute hosts 17 research groups working at
the interface of chemistry and biology in a new building (6000 sq meters) with
state of the art equipment and facilities (http://www.iecb.u-bordeaux.fr). The
scientific policy of the Institute is under the responsibility of an
International Scientific Board in charge of the selection of new group leaders.

IECB is recruiting PROJECT LEADERS in

STRUCTURAL BIOLOGY (CRYSTALLOGRAPHY, NMR)
We seek biochemists working on structure/function relationship of biological
macromolecules or on molecules of biomedical interest in particular in the
field of neurobiology.

MOLECULAR MODELLING
We seek a molecular modelling chemist with a good practice in protein-ligand
and protein-protein interactions interested in developing innovative research
in biomedically relevant areas including cancer.

BIO-INSPIRED NANOTECHNOLOGY
We seek a biochemist/biophysicist developing protein/nucleic acid scaffolds,
devices of potential interest in the field of technologies for health.

MOLECULAR CELL BIOLOGY
We are interested in projects on macromolecules or processes related to cell
cycle, gene expression or signal transduction in connection with human
pathologies.

BIOLOGICAL CHEMISTRY
We seek a chemist to develop a research program aiming at exploring biological
processes using the tools of organic synthesis.

We are looking for motivated young scientists who will demonstrate a
strong potential for the development of an ambitious research
programme. The applicants are expected to run independent and creative
projects. They should be open to interdisciplinary collaborations with
other groups of the Institute. Successful candidates will have access
to state of the art facilities in structural biology, chemistry,
molecular and cellular biology. The candidates might be asked to apply
for start-up funding such as ATIP-Avenir Inserm-CNRS programme or ANR
support.
The applicants should be fluent in English. Knowledge of French would
be useful but not mandatory. Applicants are invited to submit -prior to
September 20, 2010- a detailed biography together with a research
project and a list of potential referees to: Dr Jean-Jacques Toulmé,
Director of IECB 2 rue Robert Escarpit 33607 Pessac Cedex, France
e-mail: jean-jacques.toulme@inserm.fr

Postdoctoral Positions in NMR Studies of Large Biomolecular Machineries

Postdoctoral Positions in NMR Studies of Large Biomolecular Machineries

In the context of a project funded by European Research Council, several postdoctoral positions are available in the NMR laboratory of the Structural Biology Institute in Grenoble (France). Positions are available on the following topics:

- Development of Isotopic labeling and NMR spectroscopy methods for the study of high molecular weight protein assemblies.

- Real-time NMR investigation of folding and mechanisms of biological NanoMachines.

The laboratory hosts three NMR spectrometers equipped with cryogenic probes (600 MHz and 800 MHz) and with a solid state MAS equipment (600 MHz). It has access to the nearby 1 GHz NMR spectrometer of the European high field NMR centre in Lyon. Applicants will also have access to a fully equipped wetlab for isotopically labeled NMR sample preparation.

Grenoble is a pleasant city situated in the heart of the French alps, and has one of Europe’s most vibrant structural biology communities centred around the European Synchroton Radiation Facility (ESRF), the Laue Langevin Institute (ILL), the Structural Biology Institute (IBS) and the EMBL Grenoble Out-Station.

Competitive salary (based on previous research experience) is offered with health insurance, retirement plan, and language training allowance. Interested candidates should forward a Curriculum Vitae in English, and electronic and postal addresses of potential references via e-mail to : diff-jobs-nmr@listes.ibs.fr

Selected publications of the team :

• Gans P, Hamelin O, Sounier R, Ayala I, Durá MA, Amero CD, Noirclerc-Savoye M, Franzetti B, Plevin MJ, Boisbouvier J. Stereospecific isotopic labeling of methyl groups for NMR spectroscopic studies of high-molecular-weight proteins. Angew Chem Int Ed Engl. 49:1958-62 (2010).

• Plevin MJ, Bryce DL, Boisbouvier J. Direct detection of CH/pi interactions in proteins. Nature Chemistry. 2:466-71 (2010).

• Amero C, Schanda P, Durá MA, Ayala I, Marion D, Franzetti B, Brutscher B, Boisbouvier J. Fast two-dimensional NMR spectroscopy of high molecular weight protein assemblies. J Am Chem Soc.131:3448-9 (2009).

• Ayala I, Sounier R, Usé N, Gans P, Boisbouvier J. An efficient protocol for the complete incorporation of methyl-protonated alanine in perdeuterated protein. J Biomol NMR. 43:111-9 (2009).

• Rasia RM, Noirclerc-Savoye M, Bologna NG, Gallet B, Plevin MJ, Blanchard L, Palatnik JF, Brutscher B, Vernet T, Boisbouvier J. Parallel screening and optimization of protein constructs for structural studies. Protein Sci.18:434-9 (2009).

• Van Melckebeke H, Devany M, Di Primo C, Beaurain F, Toulmé JJ, Bryce DL, Boisbouvier J. Liquid-crystal NMR structure of HIV TAR RNA bound to its SELEX RNA aptamer reveals the origins of the high stability of the complex. Proc Natl Acad Sci U S A. 105:9210-5 (2008).

• Sounier R, Blanchard L, Wu Z, Boisbouvier J. High-accuracy distance measurement between remote methyls in specifically protonated proteins. J Am Chem Soc. 129:472-3. (2007).

Dr Jerome Boisbouvier
NMR Laboratory
Institut de Biologie Structurale
41 rue Jules Horowitz
38027 GRENOBLE Cedex 1
FRANCE

http://www.ibs.fr/content/ibs_eng/presentation/lab/lrmn/

one-year renewable postdoctoral position

A one-year renewable postdoctoral position is available in the laboratory of
Magnetic Resonances (LRM) at CEA/INAC in Grenoble (France) under the
supervision of Dr. M. Bardet.

The candidate will be involved in a joint project with the Advance Battery
Laboratory (LBA) of CEA/LITEN in Grenoble which aims at improving the
understanding of Li-ion battery properties (calendar life, cycle life, shelf
life, etc.) through the use of appropriate solid-state NMR experiments.

The candidate will have the opportunity to strongly interact with
solid-state NMR researchers (Coll. Dr. S. Hediger, Dr. G. De Paëpe). He or
she will be involved in material sample preparation at LBA (Coll. Dr. S.
Patoux, Dr. J. F.Martin) as well as in NMR data interpretation through the
use of DFT calculations (Coll. Dr. J.M. Mouesca).

The candidate will also have the opportunity to complement the NMR data with
the use of other methods (IR, XPS, EIS…) available at INAC and to access the
large scale facilities (ESRF, ILL) in Grenoble.

We are seeking a candidate with strong background in solid state NMR applied
to Li-ion batteries. Prior knowledge in DFT calculations will be highly
appreciated but is not mandatory. Candidates must be fluent in English
(written/spoken). Applicants can have any nationality. The position can
start from September-october 2010. The monthly salary is 2200 € (before
tax). Interested candidates should send a CV and three recommendation
letters to: michel.bardet@cea.fr
_____________________________________________________________

Sabine Hediger
INAC/SCIB/LRM
CEA Grenoble
17 rue des Martyrs
38054 Grenoble Cedex 9
France

Tel.: +33 4 38 78 68 12
Fax : +33 4 38 78 50 90

Email : sabine.hediger@cea.fr

Chemisch-Technische/r-Assistent/in

Chemisch-Technische/r-Assistent/in, zum 1.10.2010, Teilzeit (19,92
Wochenstunden), befristet bis 31.12.2012
Vertretung

Universitaet zu Koeln, Department fuer Chemie, NMR-Abteilung

Ihre Aufgaben:
Sie betreuen die NMR-Geraete der Abteilung und fuehren selbstaendig Routine- und
Spezialmessungen durch. Sie verstehen sich als Dienstleister/in fuer die
Wissenschaftler/innen und Studierenden, die Sie in Bezug auf die
Experimente beraten. Außerdem uebernehmen Sie einfache Wartungsaufgaben.

Ihr Profil:
Sie haben eine Ausbildung zum/zur CTA oder gleichwertige Qualifikation und
Berufserfahrung auf dem Gebiet der Instrumentellen Analytik – im optimalen Fall
in der NMR-Spektroskopie. Englischkenntnisse und der Umgang mit moderner
Buerotechnik sind fuer Sie selbstverstaendlich. Sie sind teamfaehig,
flexibel, verantwortungsvoll und belastbar.

Bei Vorliegen der tarifrechtlichen Voraussetzungen erfolgt die Eingruppierung in
Entgeltgruppe 6 TV-L.

Bitte senden Sie Ihre schriftlichen Bewerbungsunterlagen an die
Geschaeftsfuehrung des Departments für Chemie, Frau Dr. Birgit Seyberlich,
Greinstraße 4–6, 50939 Koeln, (birgit.seyberlich@uni-koeln.de).

---------------------------------------------------------


Dr. Nils Schloerer Department fuer Chemie der Universitaet zu Koeln NMR-Abteilung Greinstr.4 D-50939 Koeln (Germany) (+49) (0)221 470 3081 (office) (+49) (0)221 470 5057 (fax) http://www.oc.uni-koeln.de/nmr/index.html

MR Scientist (m/f) position, GE Global Research Munich, Germany

------------------
MR Scientist (m/f)
------------------
Please only apply online through the following link: www.ge.com/researcheurope Job # 1016545

Responsibilities
----------------
As an MR scientist, you will be developing new techniques and algorithms in magnetic resonance imaging, magnetic resonance spectroscopy, or functional magnetic resonance imaging. Broad goals of this position are the improvement of image quality, development of new technology that will enhance the MR system performance, clinical performance and efficacy.

You will be expected to work independently and also within a larger team to innovate and push the technical envelope in all aspects of magnetic resonance imaging. You will have access to a state-of-the-art 3.0T whole body MR scanner.
Your main responsibilities are:
- Apply knowledge and experience in MR physics to develop new technological solutions for MR imaging
- Work with clinical partners to refine emerging technology for clinical applications
- Maintain external visibility through conference presentations and peer-reviewed publications

Qualifications
----------------
- A Ph.D. in Medical Physics, Electrical Engineering, Chemistry or Biomedical Engineering or a Masters Degree in Medical Physics, Electrical Engineering, Chemistry or Biomedical Engineering. At least 3 years experience in the field
of magnetic resonance imaging (including time in graduate school) is desired.
- A demonstrated record of research and development in MR imaging as evidenced by conference proceedings and peer-reviewed publications
- Proficiency in programming of MR pulse sequences or image reconstruction algorithms, and demonstrated expertise in MR physics.
- A strong foundation in MR systems architecture is required
- Proficiency in programming in C, simulation tools (MATLAB, IDL, Mathematica, etc.).
- Excellent academic track record and proven scientific achievements
- Excellent communication skills
- Ability to work in a matrix environment
- Can-do attitude
- Open, creative & flexible
- Team-work & commitment
- Global mindset & customer focus
- Solution oriented & pragmatic
- Entrepreneurial mindset & acquisition expertise
- Fluency in English

Desired
----------------
- Basic German

-------------------------------------------
GE Global Research
-------------------------------------------
GE Global Research is one of the world's largest and most diversified
industrial research laboratories. The key technologies of our new
European Research Center in Munich range from renewable energies,
environmental and sensors technologies and composite manufacturing
to advanced clinical applications.
To get to know more about us, log on to www.ge.com/researcheurope.
Go for a future full of possibilities
-------------------------------------------

-------------------------------------------
Dr. Marion I. Menzel
Imaging Technologies Europe
GE Global Research

T +49 89 55 283 730
F +49 89 55 283 185
E marion.menzel@research.ge.com
www.ge.com/research

Freisinger Landstr. 50
85784 Garching bei München
Germany

GE Global Research, Zweigniederlassung der General Electric Deutschland Holding GmbH. Sitz von/Registered Office of General Electric Deutschland Holding GmbH: Neu-Isenburg.
Registergericht/Commercial Register: Amtsgericht/Lower District Court Offenbach; HRB 10773. Geschäftsführer/Managing Director: Werner van Wickeren, Udo Klaeren.
GE imagination at work

two positions (1 RF engineer and 1 Pulse Sequence Developer)

This is to inform you about two positions (1 RF engineer and 1 Pulse
Sequence Developer) just opened in Pisa to work with a GE 7T system,
which will be installed later this year.

http://www.inpe.unipi.it/imago7/job_position_img7T_eg.pdf
http://www.inpe.unipi.it/imago7/job_position_img7T_it.pdf

http://www.inpe.unipi.it/imago7/job_position_rfcoil_eg.pdf
http://www.inpe.unipi.it/imago7/job_position_rfcoil_it.pdf

If you are interested or know a good candidate who would be interested,
please have a look at the details or forward this information. These
scientists will work in close collaboration with the GE MR Applied
Science Lab at one of GE's key academic sites in Europe.

Assistant Professor position(s) in Physical Chemistry

Assistant Professor position(s) in Physical Chemistry

An opportunity exists for post(s) in physical chemistry at the University of Warwick. Physical Chemistry will be interpreted broadly across all relevant areas of activity, with magnetic resonance (both NMR and EPR) being possible areas of appointment.

For Further details please see https://secure.admin.warwick.ac.uk/webjobs/jobs/academic/job12168.html

Warwick has a state of the art Magnetic Resonance Laboratory opened in summer 2008. Applicants who can make links with the Centre and make use of these outstanding facilities are encouraged to reply. For more details about the Centre please see

http://www2.warwick.ac.uk/fac/sci/physics/research/condensedmatt/nmr/

The Head of Physical Chemistry is Prof. Tim Jones T.S.Jones@warwick.ac.uk who is happy to answer informal approaches.

Mark E. Smith
Department of Physics
University of Warwick
Tel: +44 - (0)24 76 522380
Fax: +44 - (0)24 76 150897
http://physweb.spec.warwick.ac.uk/nmr/nmr.html

For appointments
Ayesha Rahman (A.Rahman@warwick.ac.uk)
Tel: 44 - (0) 24 765 23965

postdoctoral position in NMR/diffusion

A postdoctoral position in NMR/diffusion in nanoporous materials is available immediately at the University of Florida (UF) in Gainesville. The research will involve combined application of hyperpolarized NMR and pulsed field gradient (PFG) NMR to study diffusion and related phenomena in materials with one-dimensional nanochannels. This project is a collaboration between Prof. Clifford R Bowers (www.chem.ufl.edu/~bowers/) and Prof. Sergey Vasenkov (www.che.ufl.edu/faculty/vasenkov/). The successful candidate will benefit from access to the resources of the National High Magnetic Field Lab (magnet.fsu.edu), including the AMRIS facility in Gainesville, FL. In particular, the 750 MHz PFG NMR spectrometer located in AMRIS is available to perform diffusion studies with ultra-high gradients at the highest magnetic field in the USA for this type of application.

Position: Funding for this postdoctoral position is provided by the National Science Foundation. The initial appointment will be in the UF Chemistry Department for a period of one year with a possibility for renewal for an additional year or two years.
Qualifications: The successful candidate should hold a Ph.D. (or equivalent) in chemistry, physics, chemical engineering or a related field. Significant prior experience with hyperpolarized NMR, diffusion NMR, or solid-state NMR is a requirement. An ability to learn new NMR techniques, high motivation, a strong publication record and fluency in English are expected.

Application: Interested candidates should send a cover letter with the description of research interests and future plans, curriculum vitae, list of publications, and the full contact details of three references by e-mail to:

Prof. Clifford R Bowers
University of Florida
Department of Chemistry
Email: russ@ufl.edu

three-years post-doctoral position

A three-years post-doctoral position is opened in the group of biomolecular NMR of the IGBMC institute in Illkirch (near Strasbourg), France.

The research project is related to the field of the chromatin remodelling processes. In particular, we are interested to decipher the molecular mechanisms underlying the interaction between specific transcription factors, such as the deubiquitination module of the SAGA complex, and the nucleosome. The work will be conducted within a highly multidisciplinary environment involving several teams of the institute (X-ray crystallography, functional genomics). The study will necessitate the production of several large molecular complexes, specifically labelled at methyl group positions to enable their observation by NMR and follow their interaction with purified nucleosomes. A particular attention will be paid to the dynamical aspects of these interactions, using relaxation measurements. More information on the system can be read in Bonnet et al., EMBO reports (in press).

We are seeking for a highly motivated candidate, displaying good skills in protein expression and purification methods and isotopic labelling schemes. The candidate should be interested in elaborating innovative and appropriate labelling strategies to study interactions between large molecular complexes. A good knowledge of biomolecular NMR methods is therefore requested.

Interested candidates should contact:
Pr Bruno KIEFFER
kieffer@igbmc.fr____________________________________________________________________
Bruno KIEFFER

Freitag, 2. Juli 2010

Faculty Positions, Univ. British Columbia

The Michael Smith Laboratories (MSL) and the Centre for High-throughput Biology (CHiBi) at the University of British Columbia are jointly
launching a major recruiting initiative and invite applications for six new faculty positions. These full-time tenure-track positions will be
filled primarily at the Assistant Professor level but exceptional candidates at a higher rank may be considered. The six new faculty will be
located in exceptional research space at the centre of campus within a highly interdisciplinary and collaborative environment that
includes biological and physical scientists and engineers, as well as proteomics and bioinformatics experts.

METABOLIC ENGINEERING and SYNTHETIC
BIOLOGY (competition # 7789)
All facets of metabolic engineering and
synthetic biology, from technology
development and computational
approaches to innovative applications, will
be considered. Applicants with an interest
in bioenergy and biorefining are
particularly encouraged to apply.

CHEMICAL, MOLECULAR AND SYSTEMS
BIOLOGY, and BIOENGINEERING
(competition # 7790)
Approaches using molecular genetics,
chemical, computational or molecular
biology or bioengineering to probe animals,
plants and unicellular organisms, and
models of disease therein, will be
considered.

COMPUTATIONAL TOOLS AND
TECHNOLOGY DEVELOPMENT
(competition # 7795)
The development of innovative
technologies, devices, computational
approaches or chemical and biophysical
techniques is welcomed, with particular
emphasis on genome-wide and high-
throughput approaches.

Successful applicants for these positions must have a Ph.D., will have demonstrated outstanding research strength and creativity, have
several years of productive experience, will be expected to contribute to high quality undergraduate/graduate teaching and to effectively
supervise graduate students, and be prepared to integrate their expertise with innovative researchers at the University. Academic
appointments could be within or between departments in the Faculties of Applied Science, Forestry, Medicine and/or Science, evidence
of teaching effectiveness would be an asset.

The Michael Smith Laboratories and the Centre for High-throughput Biology comprise a diverse group of 22 research and teaching faculty
and over 150 graduate students, post-doctoral fellows and research associates. Research strengths include medical and animal
molecular genetics/biology, plant and forest molecular genetics/biology, bioprocess engineering, chemical biology, proteomics, micro-
fluidics bioinformatics and statistical genomics. Importantly the group is also providing leadership for the Bio-energy and Refining
Innovation (BERI) network as part of a university-wide initiative in sustainability. Applicants are strongly encouraged to visit
http://www.michaelsmith.ubc.ca/ and http://www.chibi.ubc.ca/ to learn more about the unique technological and research
opportunities available to new faculty members. Substantial start-up funds and exceptional mentoring will be provided.

UBC with over 12,000 faculty and staff plus 8,000 graduate students, has deep research strength across the Applied Sciences, the Life
Sciences, the Physical Sciences and Computation, and has formal associations with research hospitals, the British Columbia Cancer
Agency, Genome British Columbia, the Genome Sciences Centre, the Centre for Drug Research and Development and the Institute for
Systems Biology in Seattle. Researchers thus enjoy numerous opportunities for stimulating and productive collaborations. Opportunities
exist to attract substantial research funding from government (e.g. Canadian Institutes for Health Research, Natural Sciences and
Engineering Research Council of Canada, Canadian Foundation for Innovation), foundations (e.g. Michael Smith Foundation, Genome
Canada) and industry.

Applications are being accepted on-line at http://www.hr.ubc.ca/careers/faculty_postings.html and should include a letter of
application indicating the appropriate competition number, a detailed curriculum vitae, a list of publications, a statement of research and
teaching interests, and the name, address, e-mail address and phone number of at least three referees. All positions are subject to final
budgetary approval. The closing date for all applications is September 14, 2010.




~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~~
Lawrence McIntosh

mcintosh@chem.ubc.ca
http://otter.biochem.ubc.ca/
office (001) 604 822-3341
lab -3029
NMR -9447
cell 604 562-9447
Departments of Biochemistry and Chemistry
Room 4.551 Life Sciences Centre
2350 Health Sciences Mall
University of British Columbia
Vancouver BC Canada V6T 1Z3
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PhD studentship in solid-state DNP/NMR - Lille, France

A three-years PhD position in solid-state DNP/NMR is available in the group of Prof. J.-P. Amoureux, University of Lille, Lille, France. It will start preferably in October 2010.

The project: The Ph.D. project aims to develop a new technique for the characterization of materials : the Dynamic Nuclear Polarization (DNP) for solid-state samples at high magnetic field. Recently the group of R. G. Griffin at MIT demonstrated that this technique is feasible at high magnetic field (9.4 T) and increases the sensitivity of nuclear magnetic resonance (NMR) by a factor of 100. Such a gain in sensitivity provided by DNP paves the way for new applications of solid-state NMR. The objectives of this Ph.D. are to study and show the potential of DNP for the characterization of important materials, such as heterogeneous catalysts used for the biofuel production. The Ph.D. will consist in preparing the catalyst samples containing paramagnetic agents, characterizing them by electronic paramagnetic resonance (EPR) and NMR spectroscopies and performing DNP experiments for such materials. The project is a collaboration between the university of Lille and Bruker company.

Facilities: Facilities for solid-state NMR spectroscopy has five superconducting magnets, ranging from 900 MHz (proton Larmor frequency) to 100 MHz. Over 20 probes enable solid-state NMR to be performed with different rotor diameters, from 1.3 mm to 7 mm. The 1.3 mm rotor can rotate at up to 70 kHz. Lille is a pleasant city situated in the heart of Europe (30 min from Brussels, 1 h from Paris, 1h from London by train). The university of Lille combines research groups with strong expertise in NMR and EPR spectroscopy as well as catalysis and material science. In particular, it is the coordinator of European project for designing next-generation bio-refinery.

The person: We seek application from national and international students who have graduated in physics or chemistry, preferably with a background in NMR. The successful applicant will be given the opportunity to work in an exciting environment with national and international collaborations.

Remuneration: The studentship includes a stipend of 20 118 € per year with health insurance and language training allowance.

Contact: Applications and informal queries about the lab and research projects should be directed by email to Jean-Paul Amoureux or Olivier Lafon. Applications should include a cover letter, a CV and contact information for two references.
Department of chemical engineering
University of Lille
F-59652, Villeneuve d'Ascq, Cedex, France
Tel : 33 3 20 43 41 43 Fax : 33 3 20 43 68 14
email : jean-paul.amoureux@univ-lille1.fr

Dr. Olivier Lafon
Department of chemical engineering
University of Lille
F-59652, Villeneuve d'Ascq, Cedex, France
Tel : 33 3 20 43 41 43 Fax : 33 3 20 43 68 14
email : olivier.lafon@ensc-lille.fr
webpage adress : http://uccs.univ-lille1.fr/spip.php?article199.fr

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Dr Olivier Lafon
Unité de Catalyse et de Chimie du Solide (UCCS) - UMR CNRS 8181
Ecole Nationale Supérieure de Chimie de Lille (ENSCL)
Cité scientifique, Bât. C7, B.P. 90108
F-59652, Villeneuve d'Ascq, Cedex, France