Mittwoch, 18. November 2009

postdoctoral position Oxford

Department of Biochemistry
University of Oxford

A postdoctoral position is available from April 1, 2010 in the University of
Oxford's Department of Biochemistry to study the structure, function, and
small-molecule antagonism of ion channels that are of high medical relevance.
The candidate will join the laboratory of Dr. Jason Schnell, and be responsible
for the development and structural analysis of ion channel systems by
high-resolution solution NMR. The main approach will be to use the tools of
biophysics (e.g. NMR, fluorescence, and ultracentrifugation) and molecular
biology in combination with functional assays (e.g. liposomal ion flux assays)
to elucidate the molecular details of activity.

The University of Oxford provides abundant resources for the production and
characterization of proteins, including access to NMR spectrometers operating
at 500 to 950 MHz. The lab is located in a new building designed to promote
collegiality and scientific collaborations:

Funding for the position is provided by the Medical Research Council for 1 year
in the first instance, with the possibility for extension.

Please check the following website for qualifications and application

For informal queries about the lab and research projects, please contact Jason
Schnell by e-mail:

Freitag, 13. November 2009

Post Doctoral Position at Massachusetts General Hospital/Harvard Medical School

Post Doctoral Position at Massachusetts General Hospital/Harvard Medical School

We have an opening for a Post Doctoral position in biomedical spectroscopy and imaging within the Pathology and Radiology departments at Massachusetts General Hospital, Harvard Medical School. We are looking for a motivated candidate with a M.D. or Ph.D. in biological science to join us and explore this unique opportunity. We are investigating the correlation of magnetic resonance spectroscopy and imaging (MRS/MRI) with histopathology and molecular biology to develop less-invasive diagnostic tools for many different types of cancer; currently we are focused on prostate, breast and lung. The availability for an interview in person in Boston will be necessary before an application can be considered.

Inquiry should address to:

Leo L. Cheng, PhD

Donnerstag, 12. November 2009

PhD Studentship

PhD Studentship in the application of OCT and MRI to the monitoring of microscopic changes in rock art monuments

An exciting new collaborative research project between the Nottingham Trent University and the English Heritage funded under the research council initiative on Science and Heritage ( is recruiting a PhD student to work on the application of Optical Coherence Tomography (OCT) and Magnetic Resonance Imaging (MRI) to the conservation of prehistoric rock art monuments.

The purpose of the research is to use non-invasive methods to image and measure porosity below the decorated surfaces of open-air rock art monuments, to increase our understanding of decay and prediction of vulnerability. Porosity is an important indicator of vulnerability, as voids are open to freeze-thaw, to rootlets and to hyphae. This work will make an important contribution to conserving these monuments. This will also open a new area of research whereby the novel combination of two non-invasive techniques (OCT & MRI) normally used in biomedical imaging is applied for the first time on rock art monuments.

The student will be based at Nottingham Trent University and work under the supervision of Dr Liang in Imaging for Art Conservation & Archaeology, Dr Bencsik in MRI and Professor Pyatt in Environmental Science & Analytical Archaeology. The student will also be expected to attend project meetings with scientists at the English Heritage and go on field trips to test the imaging methods on rock art monuments.

The PhD studentship would suit a highly motivated person with interest in imaging science, in particular MRI, optical interferometry and hyperspectral imaging. Interests in art conservation/history are desirable but not essential.

Minimum entry requirement: a first class or upper second class Honours degree (or equivalent) in physics, engineering, geology, archaeological science, conservation science, computer science, forensic science, chemistry and other physical sciences.

Award: the studentship offers a stipend of £15,313 (tax free) per annum for 3 years and Home/EU student fees.

Eligibility: applicants from the UK are eligible for a full award of stipend and tuition fees. Students with a relevant connection to an EU country other than the UK are eligible for fees only. However, an EU candidate may be eligible for a full award if a relevant connection with the UK has been established. A relevant connection may be established if an EU national has been in full time education in the UK throughout the three years preceding the start date of the course. International candidates are not eligible to apply for this studentship.

Closing date: 30th November 2009

For informal enquiries, please contact:

Dr Haida Liang: , +44 (0) 115 848 8056
Dr Martin Bencsik:, +44 (0) 115 848 8057
For an application form, please contact:
Ms. Rebecca Palfrey
Research & Graduate Studies Office
Erasmus Darwin Building
Nottingham Trent University
Clifton Lane,
Nottingham NG11 8NS
Telephone: +44 (0)115 848 3269
Completed applications, with copies of academic certificates, should be returned to Rebecca Palfrey.

Applications by CV only will not be accepted

Postdoctoral Position: Solution NMR Spectroscopy of Membrane Proteins Folding and Misfolding of Membrane Proteins

Postdoctoral Position:
Solution NMR Spectroscopy of Membrane Proteins
Folding and Misfolding of Membrane Proteins

The lab of Chuck Sanders at Vanderbilt University has openings for postdoctoral fellows to conduct solution NMR-based structural studies of membrane proteins and/or studies of membrane protein folding. Possible projects include characterization of the structure of the complex of diacylglycerol kinase with its substrates (follow-up to Van Horn et al. SCIENCE 324, 1726-1729, 2009), studies of the folding and misfolding of DAGK or human peripheral myelin protein 22, structural studies of integrins, and structural and functional studies of the human KCNE family of membrane proteins, which modulates potassium channel function. More information on these projects may be found at the lab web site listed below. The Vanderbilt Biomolecular NMR Spectroscopy Laboratory will soon install a 900 MHz instrument to complement current cryoprobe-equipped 800, 600, and 500 MHz NMR spectrometers. Vanderbilt University is listed as one of FORTUNE’s 2009 “100 Best Companies to Work For”.

Candidates should have an interest in working with integral membrane proteins and have relevant biochemical and/or spectroscopic experience. Start dates are flexible. Candidates should send a CV, including contact information for references, to:

Prof. Charles R. Sanders
Dept. of Biochemistry and Center for Structural Biology
Vanderbilt University
Nashville, Tennessee 37232-8725 USA
Phone: (615)-936-3756

Lab web site:


Im Teilinstitut Polymerwerkstoffe in der Abteilung Oberflächenmodifizierung die Stelle eines/einer Forschungsingenieurs/in / Techniker/in mit 40 Wochenstunden zu besetzen.

Aufgabenbeschreibung: Sicherstellung des Betriebes im Labor für Magnetische Kernresonanz (NMR) einschließlich Updates, Archivierung und Fehlersuche Einarbeitung in die Bedienung der Spektrometer und selbstständige Durchführung von Experimenten Entwicklung, Weiterentwicklung und Aufbau von Baugruppen und Experimentaufbauten sowie die Kopplung von Messgeräten und Computern

Einstellungsvoraussetzungen: Studium (FH) der Elektrotechnik oder Nachrichtentechnik, profunde Kenntnisse in Hochfrequenztechnik, Mikrowellentechnik und Digitalelektronik, Computerkenntnisse, Programmiererfahrung

Postdoctoral research associate in the Durham Solid-State NMR group

A postdoctoral research associate position is available in the Durham Solid-State NMR group from early 2010.

This 3 year position is the key staff appointment in a significant collaborative project to determine the performance limits of homo- and hetero-nuclear decoupling in organic solid-state NMR, with the goal of understanding and developing methods to maximise performance in state-of-the-art experiments involving high magnetic fields and ultra fast magic-angle spinning. The work in Durham will focus on the acquisition of reference data sets and the development of numerical simulations. This work will be closely coordinated with experimental work based at Warwick (Dr S. P. Brown) and theoretical work at ETH Zurich (Dr M. Ernst), but will also be integrated with a wider research effort involving groups across Europe (Emsley, Kentgens), Canada (Goward) and Japan (Takeda), as well as the pharmaceutical companies, AstraZeneca and GlaxoSmithKline, plus support from instrument manufacturers (Bruker, Varian). The challenging objectives of the project mean that applicants must have a strong background in solid-state NMR theory and practice. Excellent IT skills are also essential, not only for the development of simulation / analysis software, but also for the maintenance of web-based collaboration tools to co-ordinate information exchange between the project partners. The high profile of the project, and the contacts with other internationally leading research groups make this a good position for applicants to develop their prior experience and to demonstrate their abilities to a wider audience.

For further information on the Durham group, go to:
For application information, go to:

Paul Hodgkinson (Durham, UK)

PhD position in Solid State NMR /Doktorandenstelle in Festkörper-NMR-Spektroskopie

PhD position in Solid State NMR /Doktorandenstelle in Festkörper-NMR-Spektroskopie

A two-year PhD position is available at the Westfaelische Wilhelms-University in Münster. Requirements for the position are a diploma (or related degree) in physics, chemistry or related field. The research program involves the synthesis and characterization of amorphous materials employing modern solid state NMR techniques. Interested candidates should send an appplication to PD Dr. Leo van Wüllen, University of Münster, Institute for Physical Chemistry, Corrensstr. 28 - 30, D48149 Münster/Germany or contact me via email (

An der WWU Münster / Institut für Physikalische Chemie ist eine Doktorandenstelle für 2 Jahre zu besetzen. Voraussetzungen für eine Einstellung ist ein abgeschossenes Studium der Physik, Chemie oder eines verwandten Faches. Im Zentrum der Promotionsarbeiten stehen Synthese und die Charakterisierung amorpher Festkörper mit modernen Festkörper-NMR-Methoden. Bewerbungen bitte an PD Dr. Leo van Wüllen, Westfälische Wilhelms-Universität Münster, Institut für Physikalische Chemie, Corrensstr. 28 - 30, 48149 Münster oder via email an (

Postdoctoral Position in Solid State NMR/Post-Doc in Festköper-NMR-Spektroskopie

Postdoctoral Position in Solid State NMR/Post-Doc in Festköper-NMR-Spektroskopie

A one-year postdoctoral research position (extendable to up to three years) is available at the Westfaelische Wilhelms-University in Münster. Requirements are a PhD in physics, chemistry or a related field and a detailed knowledge of Solid State NMR techniques. The research program involves the development and implementation of novel solid state NMR methods for the in situ characterization of chemical and physical processes. Interested candidates should send an application to PD Dr. Leo van Wüllen, University of Münster, Institute for Physical Chemistry, Corrensstr. 28 - 30, D48149 Münster/Germany or contact me via email (

An der WWU Münster / Institut für Physikalische Chemie ist eine Postdoktorandenstelle für 1 Jahr (erweiterbar auf 3 Jahre) zu besetzen. Die Aufgaben umfassen die Entwicklung und Anwendung neuer Festkörper-NMR-Methoden zur in-situ Charakterisierung chemischer und physikalischer Prozesse. Einstellungsvoraussetzung bildet eine Promotion in Physik, Chemie oder einem vergleichbaren Fach.

Bewerbungen bitte an PD Dr. Leo van Wüllen, Westfälische Wilhelms-Universität Münster, Institut für Physikalische Chemie, Corrensstr. 28 - 30, 48149 Münster oder via email an (

ERC-funded postdoctoral fellowships available at Weizmann

In connection to the impending signing of an Advanced Research Award by the European Research Council in support of our research, I am looking to hire two post-doctoral researchers in support of work to be carried out at Weizmann over a 2-3 year period within the 2010-2014 calendar years. These hirings offer ample flexibility, and are meant to deal with a number of multidisciplinary problems within the field of magnetic resonance in its broadest sense; involving solid state studies of hyperpolarized quadrupolar nuclei and spin-1/2 in biomolecules, in vitro and biological DNP NMR, in vivo NMR/MRS spectroscopy, ultrafast multidimensional spectroscopy of biophysical rearrangements, and functional MRI and MRS. Our aim is in fact to bring together complementary aspects of solid state, solution, in vivo, DNP and imaging NMR spectroscopies, towards the development of new methodologies and hitherto unachievable applications. The candidate should have a strong background in at least one of these magnetic resonance areas (at a Ph.D. level), and a willingness to be exposed to the remaining ones. Specific expertise in magnetic resonance software and hardware (EPR, NMR, MRS or MRI) is required.

The Weizmann Institute is located in a small, affordable and friendly town at the feet of the Judean hills, and is one of Israel's premier scientific institutions. It is a research center whose official language is English and which offers numerous facilities to international visitors, including furnished apartments for visiting postdocs (and their families). From its inception the Institute has shown an unequivocal commitment to all areas of magnetic resonance and over the years it has made extensive investments in NMR faculty, staff and in infrastructure. As a result the Institute possesses an 800 MHz NMR with a cryoprobe, a 600 MHz widebore triple-resonance solids/liquids/imaging machine, a 3 T whole-body MRI scanner, a 95 GHz pulse EPR spectrometer, a 9.4 T animal MRI scanner, an OI Hypersense DNP, para-hydrogen NMR facilities, and numerous (dozens) of other NMR instruments placed in various magnetic resonance buildings as well as several groups involved in all areas of magnetic resonance. As a result of the impending ERC support, the incorporation of significant new MR hardware is also planned.

Those interested in being considered for these positions should send their Vitae and at least two References to Thanking you in advance for bringing this notice to the attention of potential candidates,

With kind regards,

Lucio Frydman

Lucio Frydman, Professor and Kimmel Fellow
Department of Chemical Physics
Weizmann Institute of Science
Rehovot, 76100 Israel
Phone: 972-8-9344903
Lab: 972-8-9344901
E. Mail :

Mittwoch, 11. November 2009

Postdoctoral position and 2-3 PhD studentships, Massey University, New Zealand

Postdoctoral position and 2-3 PhD studentships, Massey University, New Zealand

A two-year postdoctoral fellowship and two to three PhD studentships are available to apply state-of-the-art NMR techniques to protein and RNA structural and dynamic analysis. This project is a collaboration with the University of Sydney, where complementary Small Angle X-ray Scattering (SAXS) studies will be performed, and with the New York Structural Biology Center. The Massey University Centre for Structural Biology houses a 700 MHz Bruker Avance NMR spectrometer with cryoprobe in addition to 500, 400 and 200 MHz spectrometers. Support is via a grant from the Royal Society of New Zealand.

Postdoctoral salary will begin at NZD 61,612 per anna. The initial appointment will be for one year (as required by University regulations), but funding is in place for a second year, subject to a standard performance review, and extension into a third year is possible pending funding decisions.

The PhD fellowships carry tax exempt stipends of NZD 23,000 per anna. There is no teaching requirement, and all student tuition and fees are covered by the grant. Students with exceptional undergraduate marks may be eligible for a University Scholarship which provides an increase in stipend level.

The nominal closing date for these positions is 25 November 2009, however late applications will be accepted until the positions are filled.

Interested parties should email a cover letter, c.v. and contact information for three referees to Associate Professor Steven Pascal.

See for email address and further information.

Steven M. Pascal
Senior Lecturer and
Director of BioNMR Research
Institute of Fundamental Sciences
Massey University
Palmerston North, New Zealand
voice: 646-356-9099 ext 3558
fax: 646-350-5682