Freitag, 26. Juni 2009

Doktorandenstelle NMR-Bildgebung

Liebe Kollegen,
in meiner Gruppe besteht kurzfristig die Möglichkeit, eine stipendienfinanzierte Doktorandenstelle im Bereich der NMR-Bildgebung zu besetzen. Es geht um methodische Arbeiten zu Kontrasterzeugung bei 7T und Verfahren der Datenauswertung mit dem Ziel der Quantifizierung. Die Methoden sollen am Kleintiermodell eingesetzt werden.
Sollte es interessierte Studenten geben, würde ich mich freuen, wenn Ihr diese Information weitegeben würdet. Interessenten sollten sich bitte telefonisch oder per email an mich wenden.
mit freundlichen Gruessen
Ulrich Scheler


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Dr. Ulrich Scheler
Leibniz Institute for Polymer Research Dresden
Hohe Strasse 6
D-01069 Dresden, Germany
phone +49 351 4658 275
fax +49 351 4658 231
www.ipfdd.de
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post-doctoral position in solid-state NMR of paramagnetic proteins

Open post-doctoral position in solid-state NMR of paramagnetic proteins

The Center for Very High Field NMR in Lyon (France) recruits a post doctoral fellow (2 years) on the structural investigation of microcrystalline paramagnetic proteins by solid-state NMR.

Techniques involving very fast MAS (70 kHz), state-of-the-art heteronuclear and homonuclear decoupling, scalar coupling transfers will be developed and applied to provide access to resolved NMR resonances from the 13C, 15N and 1H nuclei close to a metal center. The goal of this project is to provide a more sensitive acquisition of multidimensional correlations, faster and less ambiguous assignment of the resonances, and more precise measurements of constraints for structural or dynamical determinations. Notably, the changes induced by the presence of a paramagnetic metal with respect to the diamagnetic case will be used to model the electronic state of the metal ion, its coordination and its reactivity.

The Center for Very High Field NMR in Lyon, which is affiliated to the CNRS (French National Center for Scientific Research) and the Ecole Normale Supérieure de Lyon, one of the leading Grandes Ecoles in France, will provide the ideal interdisciplinary (physics – chemistry – biology) environment and the necessary facilities to carry out the project. The center is equipped with state of the art NMR spectrometers (500 - 700 - 800 MHz, and the world's first 1 GHz spectrometer is being installed in the center in the coming July 2009), and hosts research groups of world-wide recognized excellence, notably in the rapidly growing field of solid-state NMR of proteins.

For more information about our center and to consult our recent publications please visit our webpage: http://www.ens-lyon.fr/crmn

The ideal candidate will preferably possess previous experience with liquid-state or solid-state protein NMR experiments. The position will be available from the beginning of January 2009. If you are interested please contact either Dr. Guido Pintacuda or Pr. Lyndon Emsley at guido.pintacuda@ens-lyon.fr and lyndon.emsley@ens-lyon.fr.

Software Quality Control Specialist

Mestrelab Research SL (www.mestrelab.com) has an opening for a Software Quality Control Specialist,

This is a full time position with a permanent contract. The successful candidate will integrate within Mestrelab’s Research and Development Department, responsible for the development of Mnova (http://www.mestrelab.com/index.php?option=com_mestrelab&Itemid=2), Mspin (http://www.mestrelab.com/index.php?option=com_mestrelab&task=ficha&id=6&Itemid=2) and other forthcoming Mestrelab software products, and report directly to Mestrelab’s Head of Development. The successful candidate must be able to relocate to Santiago de Compostela, as this in mainly an office based position, and must be available to conduct a face to face second interview in Santiago (first interviews for candidates living remotely can be carried out via web meeting).

The requirements for this position are:
Chemistry or Biochemistry qualification (BsC, MsC or PhD)
Excellent level of written and spoken English.
Demonstrable experience with Analytical Chemistry Software as an user.

In addition, the following will be an advantage:
Demonstrable software testing or software programming experience
Demonstrable experience in Cheminformatics
Any additional qualifications or experience in the field of Analytical Chemistry
Any additional languages fluently spoken.

The successful candidate will be responsible for the ongoing Quality Control of all Mestrelab’s software products under development, and for the setting up of robust software testing protocols, as well as for the preparation of technical documentation and for occasional customer support tasks. This is a newly created position with potential for further growth and development.

All candidates interested in the position should send their CV and any additional documentation by email to info@mestrec.com.

Santi Dominguez
CEO
Mestrelab Research SL
Feliciano Barrera 9B, Bajo
15706 Santiago de Compostela
Spain
Tel: +34881976775
Cell: +447815799765
Email: sdominguez@mestrec.com
Web: http://www.mestrelab.com
Blog: http://blog.mestrec.com & http://nmr-analysis.blogspot.com/

Post-Doc in NMR-based metabolomics

1) Post-Doc in NMR-based metabolomics of C. elegans

A postdoctoral position is open at the Center for Molecular and Cellular Genetics, Lyon, France (Segalat lab.), to pursue our work in C. elegans NMR metabolomics. This is a joint project with the High-Field NMR Center (CRMN) in Lyon.

We are looking for a motivated candidate to pursue this work in two directions :

1. Identification of metabolic pathways involved in several C. elegans models of muscle diseases.

2. High-scale functional genomics of C. elegans by a NMR metabonomics approach

We are looking for a qualified applicant in NMR metabolomics. A background in Biology/Biochemistry will be an advantage.

The Center for Molecular and Cellular Genetics (CGMC) and the Center for High Field NMR are located on the campus of the University Claude Bernard. They are funded by CNRS, the University Claude Bernard, ENS-Lyon, and multiple additional sources. Both laboratories provide an excellent scientific environment with state-of-the-art facilities. Our labs are pioneers in the emerging field of invertebrate metabolomics (Proc Natl Acad Sci (2007) 104:19808-12).

This position is available in September 2009 for one year, renewable (CNRS contract). It will be based at the CGMC in Lyon (Villeurbanne).

For additional information, visit our institute websites: http://www.cgmc.univ-lyon1.fr/eq_segalat.php and http://www.crmn-lyon.fr

For position n°1: Please send your application and CV by e-mail to Dr. Laurent Ségalat : segalat@cgmc.univ-lyon1.fr (tel/fax : +33 4 72 43 29 51). Other contact: Dr. Bénédicte Elena : benedicte.elena@ens-lyon.fr

2) Post-doc in NMR-based metabonomics and predictive toxicology

A post-doctoral position is available at the High-Field NMR Center (CRMN) of the Ecole Normale Supérieure de Lyon, France. The project runs for two years.

The CRMN in Lyon is a European facility for NMR and is particularly well equipped with a 500 MHz, a 700 MHz, a 800 MHz and will host the first 1 GHz NMR spectrometer (summer 2009).

The successful candidate should have should have a background in either of the areas: 1. Analytical Chemistry, 2; Metabolomics, 3. Bioinformatics / Chemometrics or a related field with several years experience in NMR spectroscopy and ideally data analysis, as the project will involve the acquisition and analysis of 1H NMR–based metabolic profiling data from bioartificial organs. He/she should have a PhD in Analytical Chemistry, Biochemistry, Biophysics, Bioinformatics, Chemometrics or a related field.

The position will involve the following areas of expertise:

* Practical experience of biological NMR spectroscopy and/or experience of HR-MAS
* Knowledge of signal processing and multivariate statistics methods would be an advantage since the project involves NMR data modelling
* Strong motivation to learn and ability to work in an interdisciplinary environment
* Good written and verbal presentation skills are essential for coordination of results with the other members of the consortium

This position is available in September 2009 for one year (one year extension possible). It will be based at the CRMN in Lyon (Villeurbanne). The applicant should be a highly motivated individual aiming to work well in a team, but should also be capable of working in an independent capacity.

For additional information, visit our institute website: http://www.crmn-lyon.fr
For position n°2: Please send your application and CV by e-mail to Dr. Pierre Toulhoat : pierre.toulhoat@ens-lyon.fr
Other contacts: Prof. Lyndon Emsley : lyndon.emsley@ens-lyon.fr ; Dr. Bénédicte Elena : benedicte.elena@ens-lyon.fr ; Dr. Marc-Emmanuel Dumas : marc.dumas@ens-lyon.fr

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Bénédicte Elena
Centre de RMN à Très Hauts Champs de Lyon
Université de Lyon, FRE 3008 CNRS / ENS Lyon / UCBL
Tel: +33.4.26.23.38.80 / Fax: +33 4 78 89 67 61

MRI physicist or engineer

MRI physicist or engineer

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Magritek Limited has a vacancy for a physicist or engineer with interests in
MRI and NMR, and familiar with electromagnetic design. In particular we
seek someone who will be able to join our team of shielded gradient and shim
coil designers, working on the development of new MRI and NMR spectroscopy
systems. The ideal candidate will have strong mathematical skills, a sound
background in physics or electrical engineering, strong computational skills
(experience with Matlab is essential and with C++ would be an advantage),
and a strong interest in translating design through to practical
implementation, through the use of Solid Works, and Altium, interacting with
our technical staff and involvement in construction and building. Ability to
test the performance prototypes using our NMR and MRI systems will be
required. The person appointed will work closely both with the research
group of Professor Paul T Callaghan at Victoria University of Wellington,
and with the R&D team at Magritek Ltd, Wellington.

Remuneration is at the postdoctoral level, with base salary depending on
experience. In addition the appointee will be part of a company bonus
scheme. The initial contract will be for two years and subject to the issue
of a work permit (necessary for non-New Zealand or non-Australian citizens).
It will carry NZ health benefits (free hospital care and subsidised
medicines). An allowance for relocation costs and travel to New Zealand is
included in the package.

Applications must include a full cv, a covering letter explaining the
applicant's background and interests in the position, and should be
accompanied by the names and email addresses of two referees familiar with
the candidates professional work. The closing date for applications is July
17th and must be addressed, by email, to

Dr Andrew Coy, CEO Magritek Ltd
andrew@magritek.com


Dr. Andrew Coy
Chief Executive Officer

Magritek Limited
32 Salamanca Road
Wellington, NEW ZEALAND
Phone : +64 (4) 920 7671
Fax : +64 (4) 473 2686
Mobile : +64 (21) 137 2017
USA Phone: +1 (415) 287 0727
UK Phone: +44 (0) 20 3287 6703
Hong Kong Phone: +852 8176 7196
Email : andrew@magritek.com
Web : http://www.magritek.com/

Donnerstag, 18. Juni 2009

NMR position in Mexico

"University of the State of Morelos" (not UNAM, where I work) that has just adquired a 700 megahetz NMR apparatus and need someone to work with.
It is a scientist position (investigator) and would have the machine to operate for protein structure determination.

Contact possani@ibt.unam.mx

Contact
Lourival D. Possani, Ph.D.
Institute of Biotechnology
National Autonomous University of Mexico
Avenida Universidad, 2001
Apartado Postal 510-3
Cuernavaca 62210
Mexico
Tel. +52-777-3171209
FAX +52-777-3172388

Donnerstag, 11. Juni 2009

Postdoctoral Position in Solid State NMR/Materials Science of Renewable Energy

Postdoctoral Position in Solid State NMR/Materials Science of Renewable Energy

A one-year postdoctoral research position, renewable for two additional years, is available at Hunter College of the City University of New York.

The research program concerns solid state NMR of materials being evaluated for electrochemical energy storage and conversion,including transition metal oxides and polymer electrolytes for lithium battery or fuel cell applications. Current and future work includes collaborative projects with U.S. National Labs and U.S. and international universities on materials for renewable energy technologies.

The requirements for the position are a Ph.D. in chemistry, physics, or engineering, and significant experience with standard solid state NMR techniques (e.g. CP/MAS) as well as pulsed field gradient diffusion methods. In addition to research, responsibilities include assisting in the training of graduate and undergraduate research students, and routine magnet/spectrometer upkeep. Facilities include a Varian 500 Inova with solid state rack and MAS probes, a Varian Direct Digital Drive 300 with widebore magnet and gradient channel, a Chemagnetics CMX 300 with gradient channel and pfg probes, a homebuilt high pressure NMR system, a Tecmag Apollo NMR system with 90 MHz permanent magnet (for paramagnetic materials), and access to the NY Structural Biology NMR Center housed at nearby City College (www.nysbc.org).

Interested persons should send a CV and the names and e-mail addresses of three references to Prof. Steve Greenbaum, Department of Physics, Hunter College of CUNY, 695 Park Avenue, New York, NY 10065; or preferably by e-mail: steve.greenbaum@hunter.cuny.edu

Postdoctoral Position in Magnetic Resonance Molecular Imaging, New York City

Postdoctoral Position in Magnetic Resonance Molecular Imaging, New York City

The Bone Cell Biology and Imaging Laboratory at the Hospital for Special Surgery/Cornell Medical School (www.hss.edu) investigates the molecular mechanisms which control bone biology in normal and damaged bone. In order to provide a direct view of the molecular and cellular events in living, intact bone, we develop and apply cutting-edge musculoskeletal molecular imaging for real-time visualization in pre-clinical models as well as in patients.

We conduct interdisciplinary, team-driven research bringing together students, scientists, physician-scientists and physicians. The lab is engaged in close collaborations with world-class in vivo NMR laboratories in New York City. Our long-range goal is to devise novel imaging protocols for patients with impaired bone integrity due to trauma, genetic alteration, or cancer.

For a highly innovative project, we are seeking a post-doctoral fellow for an at least two-year engagement. The project aims at the development of fluorine magnetic resonance spectroscopic imaging of bone cell activity in living subjects. Applicants must have excellent knowledge of magnetic resonance imaging and spectroscopy, and a strong interest in biology is expected.

We are looking for an individual with the ability to work independently, outstanding communication skills, the desire to work in a multi-disciplinary environment and skills to master challenging research. Our laboratory provides outstanding resources, dedicated mentoring and a highly motivating work place. This position offers a competitive salary, benefits and vacation package. To apply, please send cover letter and full CV to Dr. Philipp Mayer-Kuckuk, E-mail: mayerkuckukp@hss.edu or mayerkup@mskcc.org.