Mittwoch, 31. März 2010

EPR postdoctoral position in physics

EPR postdoctoral position in physics (University of Dundee and University of St Andrews)

A postdoctoral position is currently available in the area of pulsed EPR methods applied to problems in Materials Physics. The post is funded by a joint award between University of Dundee and University of St Andrews and will utilise 9, 34, and 95 GHz pulsed EPR and ENDOR facilities. The focus of the project will be study technologically relevant native and impurity point defects in emerging functional materials.

Further information is available from, and preliminary applications should be submitted to:

Dr. David Keeble
School of Engineering, Physics, and Mathematics,
University of Dundee,
Dundee DD1 4HN
Scotland
UK

Tel +44 1382 384561

d.j.keeble@dundee.ac.uk

Scientist/Engineers and Specialist position

On behalf of NMR core lab. of King Abdullah University of Science and Technology (KAUST), I would like to post the Scientist/Engineers and Specialist position of Solid State and Liquid NMR.

Please send inquiries to Dr. Xixang Zang or myself.
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Employer: King Abdullah University of Science and Technology (KAUST)

Background
Multiple NMR positions (scientist/engineer and specialist) are immediately available in the NMR core lab at King Abdullah University of Science and Technology. The NMR core lab houses several state-of-the-art Bruker (Avanace III) NMR spectrometers including, 400, 600 and 900 MHz solid, 400, 500, 600, 700, and 950 MHz liquid equipped with cryogenic probes.

The candidate will be a member of a multi-disciplinary, multi-national team of NMR professionals. Good oral and written communication skills in English are required. Interested candidates, with a good background in either solution or solid state NMR spectroscopy, should email a cover letter, CV and the names of at least three references. to Dr. Xixang Zang at xixiang.zhang@kaust.edu.sa.

Duties
Maintain state-of-the-art Bruker NMRs (950 MHz, 900 MHz 700MHz in total 10) for biological and materials applications.
- Operate and Maintain cryogenic probes.
- Provide strong support in both technical (data acquisition) and scientific (data interpretation) to KAUST users.
- Explore all the functions of state-of-the-art instruments.
- Develop and execute a calibration program for all equipment.
- As time permits, develop experimental processes and procedures to meet specific user needs.

Qualifications
A good knowledge of NMR theory and excellent technical skills, with an ability to work in a team of faculty, staff and students. Training will be made available either at KAUST or at other NMR centers.

Education
- Ph.D in science and engineering Experience
- 5-6 years experience in NMR. Experience with one or more platform-independent data processing packages is strongly desired.

Additional Notes
Candidate for NMR specialist, should have a good knowledge of NMR principle/mechanism and excellent technical skills, with an ability to work in a team of faculty, staff and students. Training will be made available either at KAUST or at other NMR centers.



Inquiries and applications should be send to by e-mail

Dr. Xixang Zang (xixiang.zhang@kaust.edu.sa)
Manager of Advanced Nanofabrication, Imaging and Characterization Core Lab,

King Abdullah University of Science and Technology

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Dr. Kazuo Yamauchi (kazuo.yamauchi@kaust.edu.sa)
Nuclear Magnetic Resonance Core Labs. (Bldg 3 Room 0153)
King Abdullah University of Science and Technology
Thuwal 23955-6900, Saudi Arabia
Tel: +966-(0)2-808-4312 Mobile: +966-(0)54-470-0658

==================================================================

PhD scholarship in protein NMR

A bright and enthusiastic student is sought to undertake studies within the NMR group at the Tokyo Metropolitan University in Japan. Funding covers tuition fees, scholarship and other benefits and is restricted to nationals of Asian countries* (see below for further details).

Our research focuses on technique development of NMR measurements inside living cells (in-cell NMR) and on development of new methods of study of larger proteins (50-100kDa range) and their interactions.

This PhD project will investigate the structure and dynamics of proteins inside living cells, initially focusing on Escherichia coli and later extending to eukaryotic cells.

For our group's previous experience with in-cell NMR method development please see:
Sakakibara et al., "Protein structure determination in living cells by in-cell NMR spectroscopy." Nature 458, 102-105 (2009)

There is also a possibility to get involved in structure determination of larger proteins. This work would focus on optimization and development of rapid NMR measurement and finding better ways of obtaining NMR structure from limited data.

Ultimately this PhD research would lead to the contribution in methodology and state-of-the-art in NMR spectroscopy.

Our NMR group has a fully equipped biochemistry 'wet lab' facilities for protein expression and purification, and our own dedicated a cryoprobe-equipped 600MHz Bruker spectrometer at Tokyo Metropolitan University. We also have access to high field NMR spectrometers at RIKEN Yokohama Institute.

Applications are encouraged from students with a relevant biological sciences or (bio)physical background. Candidate must have, or be expected to receive, a Masters or equivalent degree. Experience in preparing/handling over-expressed proteins would be advantageous. Some experience in biomolecular NMR is preferable, but not necessary.

Language: Ability to communicate in English in speaking and writing.

Funding Source: "Asian Human Resources Fund" PhD scholarship from Tokyo Metropolitan Government. Scholarship of 170,000 yen a month and other benefits (housing, health insurance, and travel subsidies) will be provided for a period of three years.

Project enquiries should be sent to professor Yutaka Ito at ito-yutaka@tmu.ac.jp (please include a CV).

Application forms are available by above email, and the formal application will be submitted to the graduate school after initial enquiry and project discussion with the candidate.
Applications period 19-30 April 2010 (postmarked).


*“Asian nations” refer to the counties or regions of the East Asia, the Southeast Asia, and the South Asia, including Bangladesh, Bhutan, Brunei, Cambodia, China, East Timor, India, Indonesia, Laos, Malaysia, Maldives, Mongolia, Myanmar, Nepal, Pakistan, Philippines, Singapore, South Korea, Sri Lanka, Taiwan, Thailand, Vietnam.

-- ================================================= Prof. Yutaka Ito Department of Chemistry Tokyo Metropolitan University email: ito-yutaka@tmu.ac.jp 1-1 Minami-Osawa, Hachioji, Tokyo 192-0397, JAPAN Tel: +81-42-677-2545 http://www.comp.tmu.ac.jp/osbc/GROUP/ito_home_e.html =================================================

Postdoctoral Research Scientists

Postdoctoral Research Scientists: Macromolecular Assembly in DNA Repair and HIV Pathogenesis.

Several Postoctoral Research Scientist positions are currently open at the University of Texas Health Science Center at San Antonio (UTHSCSA) to work on the structural basis of protein recruitment to large macromolecular complexes. Two separate research projects, one in DNA damage sensing and repair, and another in HIV assembly and restriction, are funded by the Cancer Prevention and Research Institute of Texas (CPRIT) and the National Institute of Allergy and Infectious Disease (NIAID) respectively. The research efforts will benefit from the state-of-the-art core facilities for structural biology and biophysics at the Department of Biochemistry, strong expertise in virology and DNA repair at the UTHSCSA, and the recently funded drug discovery infrastructure at the Center for Integrative Nano-Medicine and Chemical Biology. The candidates will have a Ph.D. in Biochemistry/Biophysics/Structural or Molecular Biology, solid training in protein chemistry and expertise in one or more of the following areas: DNA repair, molecular basis of HIV pathogenesis, protein NMR, X-ray crystallography, drug discovery.

The University of Texas Health Science Center at San Antonio is one of the leading biomedical research institutions in Texas with almost $200 million in annual research spending. Successful applicants will join the Department of Biochemistry, one of seven basic research departments at UTHSCSA, that houses 5 of the 11 University-supported Core Facilities. Facilities for structural biology include cryoprobe-equipped 600MHz and 700MHz Bruker spectrometers, Rigaku 007H generator linked to two state-of-the-art detectors, and a robotic system for crystallization screens.

The city of San Antonio is a major tourist attraction in the state of Texas with an animated downtown and a very reasonable cost of living.

Inquiries and applications should be directed by email to Dr. Dmitri Ivanov (ivanov@uthscsa.edu; http://ivanovlab.uthscsa.edu). Applications should include a CV, brief description of research interests and contact information for references. Start dates are flexible.
--
Dmitri N. Ivanov, Ph.D.
Assistant Professor
CPRIT Scholar in Cancer Research
Department of Biochemistry, MSC 7760
University of Texas Health Science Center
7703 Floyd Curl Drive
San Antonio, TX 78229-3900

phone: 210-567-8781
fax: 210-567-8778

email: ivanov@uthscsa.edu

webpage: http://ivanovlab.uthscsa.edu

Freitag, 12. März 2010

Macromolecular Spectroscopist Position at NCI-USA

The Structural Biophysics Laboratory (SBL; http://ccr.cancer.gov/labs/lab.asp?labid=43) at the National Cancer Institute (part of the NIH) has an opening for dedicated Macromolecular NMR spectroscopist support who will work with the Investigators in the SBL and the NMR Engineer in the Molecular Discovery Program (MDP).

The SBL operates high-field NMR spectrometers ranging in frequency from 500 to 800 MHz and each spectrometer is equipped with a cryogenic triple resonance NMR probe optimized for studies on macromolecules (proteins and nucleic acids). The instruments are made by both Varian and Bruker. There are presently two PI-led groups conducting research, and expansion to add a third research group will occur in 2010.

We require the support of a skilled NMR spectroscopist to work with the PIs, postdoctoral fellows, and staff scientists in the SBL. Duties include:
1) Training and assisting users in operation of sophisticated multi-dimensional NMR experiments on macromolecules
2) Maintenance and development of experimental protocols (either as implementation of published methods or de novo development of new methods, with opportunity to collaborate with PIs in the SBL)
3) General instrument oversight, including scheduling and supervision of cryogen and magnet maintenance
4) Cooperation with on-site NMR engineer for trouble shooting and problem resolution

The spectroscopist should have a PhD and postdoctoral experience in macromolecular NMR. Demonstrated experience/expertise with Varian and Bruker systems is essential.

This spectroscopist will participate cooperatively in a three-member team to provide overall support for the NMR resources within the MDP ( http://ccr.cancer.gov/labs/lab.asp?labid=849).


Information and applications are made at the posting at http://www.saic-frederick.com/careers/
and go to View Openings, lower right on the page
on the search page select Scientist I 168578


===============================================
R. Andrew Byrd 301-846-1407
Dir., Molecular Discovery Program
Chief, Structural Biophysics Laboratory FAX 301-846-6231
Macromolecular NMR byrdra@mail.nih.gov
http://ccr.cancer.gov/resources/sbl/

Center for Cancer Research
National Cancer Institute-Frederick
P.O. Box B, Bldg. 538
Frederick, MD 21702-1201
===============================================

Fellowship in management of Science and Technology

Fellowship in management of Science and Technology is available, starting immediately, with the duration of 1 year, but extendable until the end of 2012, depending on performance. The successful candidate will manage the University of Aveiro Pole of the Portuguese National Nuclear Magnetic Resonance Network (http://ptnmr.dq.ua.pt).

Place: Nuclear Magnetic Resonance Laboratory of the Chemistry Department, University of Aveiro, Portugal.

Salary: in the range 1495-1995 €/month

Profile of the Candidate: Ph.D. in Chemistry, Physics, Biochemistry, Materials Sciences or related areas.

Deadline: 15 April 2010.

Documents: Please submit a motivation letter, detailed Curriculum Vitae, copy of the Ph.D. degree certificate, and contact details for 2 referees to (preferably by e-mail):

Prof. Joao Rocha
Departamento de Química
CICECO
Universidade de Aveiro,
3810-193 Aveiro
Portugal
Tel. (+351) 234 370730
e-mail: rocha@ua.pt

The NMR Laboratory in Aveiro houses 3 spectrometers (300 MHz liquids, 500 MHz liquids+solids+LC, and 400 MHz solids) and is part of CICECO, one of the main materials science institutes in Portugal (http://www.ciceco.ua.pt).
Please see more details at:
http://ptnmr.dq.ua.pt/index.php/jobs-a-grants/84-fellowship-in-management-of-science-and-technology

Transmitted on behalf of João Rocha.

Luís Mafra

Two pre-doctoral grants

Two pre-doctoral grants in in the Chemistry Department in Faculdade de Ciências e Tecnologia, Universidade Nova de Lisboa, Portugal
are available in the framework of the Project

Study of intermolecular interactions in alternative solvents: A NMR based contribution to sustainable chemistry

Ref. BI/PTDC/QUI-QUI/098892/2008/1
Comprehensive and systematic NMR study of solute/solvent interactions in scCO2

Ref. BI/PTDC/QUI-QUI/098892/2008/2
Comprehensive and systematic NMR study of Ionic Liquid structure and solute/solvent interactions


Requirements
Requirements for the position are a master diploma (or related degree) in Chemistry, Physics, material science or related fields. Preference will be given to candidates with previous experience in NMR
Salary: 980 €/month
Researchers will be contracted in full-time in accordance with the regulations for the advanced formation of human resources from the Portuguese Foundation for Science and Technology FCT-MCTES (http://www.fct.mctes.pt/pt/apoios/formacao/ambitoprojectos) and the grants regulations from Fundação da FCT/UNL.

Applicants should send: Detailed Curriculum Vitae, motivation letter and at least one letter of reference by email to Prof. Eurico Cabrita (ejc@dq.fct.unl.pt)

Application deadline: 9th March 2010

For informal enquiries, please contact Professor Eurico Cabrita e-mailing

********
Eurico J. Cabrita
Professor Auxiliar
Departamento de Química
Faculdade de Ciências e Tecnologia
Universidade Nova de Lisboa
2829-516 Caparica
Portugal
Gab: +351 212948358 (directo)
Lab: + 351 212948300 ext 10900
Fax: +351 212948385

Experimental Officer (NMR / MRI)

Experimental Officer (NMR / MRI) Ref: 7493

Up to £32,620 (subject to experience and qualifications)

Appointment for 3 years in the first instance

Based within the Nuclear Magnetic Resonance laboratories of the Department of Physics, you will be responsible for the development of experimental equipment and pulse sequences, as well as for data analysis software used in support of related research projects.

You will have a BSc and relevant practical experience or a PhD in Physics, Chemistry or related discipline using magnetic resonance. In addition, you will have the ability to work alongside postgraduate and post-doctoral researchers and contribute actively to research projects.

For informal enquiries, please contact Professor Peter McDonald by e-mailing p.mcdonald@surrey.ac.uk or telephoning 01483 686798.

For full job and application details, and to apply online, visit _http://www.surrey.ac.uk _ and click on ‘Job Opportunities’. If you are unable to apply online, please contact Mrs Claire Trussler on tel: +44 (0) 1483 686126 or e-mail c.trussler@surrey.ac.uk

Closing date: 8 April 2010

/We acknowledge, understand and embrace cultural diversity/

transmitted on behalf of Peter McDonald by G. Jeschke

--
Prof. G. Jeschke
Physical Chemistry
ETH Zurich
8093 Zurich Switzerland

E-mail: Gunnar.Jeschke@phys.chem.ethz.ch
Tel.: +41-44-6325702

EPR Research Assistant

EPR Research Assistant position in the
Department of Chemistry, McGill University

Applications are invited for a research assistant in the general area of EPR spectroscopy in the Centre for Self-Assembled Chemical Structures (CSACS), McGill University, Montreal, Canada. The duties for the position are to assist in research related to materials science, free radical biology, and bioinorganic chemistry and to train students in the use of our new Bruker ELEXSYS FT-EPR. A successful candidate will have a PhD in physical chemistry with extensive hands-on EPR experience and good knowledge of pulse magnetic resonance spectroscopy. Exceptional candidates with an MSc degree and extensive EPR experience will also be considered.

The position is available immediately and will entail a year to year contract and remuneration at a level comparable to a postdoctoral position.

Interested applicants should apply with a CV and arrange for three letters of reference to be sent directly to Prof. Perepichka (dmitrii.perepichka@mcgill.ca)

Centre for Self-Assembled Chemical Structures
Department of Chemistry
McGill University
801 Sherbrooke str West
Montreal H3A 2K6
CANADA

transmitted on behalf of Prof. Linda Reven, McGill University by G. Jeschke

--
Prof. G. Jeschke
Physical Chemistry
ETH Zurich
8093 Zurich Switzerland

E-mail: Gunnar.Jeschke@phys.chem.ethz.ch
Tel.: +41-44-6325702

postdoctoral position physics department TU Dortmund

A postdoctoral position is presently available in the physics department of the Technical University of Dortmund. The successful candidate will participate in a newly established cooperative research project involving German and Japanese partners. The goal of this project is the development of a quantum computer using the N/V center of diamond as qubits. The main task of the Dortmund team is the development of precise and robust quantum gate operations for these spin-qubits.
Additional information and an overview of current research projects are available at
http://e3.physik.uni-dortmund.de/de/E3a/ResearchInterests/
The successful candidate should have experience in magnetic resonance, quantum computing and / or quantum optics / laser spectroscopy.
The Technical University of Dortmund is an equal opportunity employer. Preference will be given to women and candidates with disabilities.
Additional information is available from and applications should be submitted to
Prof. Dieter Suter
Fakultät Physik
Technische Universität Dortmund
D-44221 Dortmund
Tel. +49 231 755 3512
Dieter.Suter@tu-dortmund.de
http://e3.physik.tu-dortmund.de

PhD Student position in computational NMR and EPR spectroscopy

PhD Student position in computational NMR and EPR spectroscopy

Topic: "Highly efficient quantum spin dynamics simulation algorithms"

Oxford University is offering a fully funded DPhil studentship in the field of theoretical and computational magnetic resonance spectroscopy under the supervision of Dr Ilya Kuprov at Oxford e-Research Centre.

This is a theoretical project dealing with an old and important problem in magnetic resonance - that of the exponential scaling of simulation complexity with the number of particles in the system. Put simply, exponential scaling means that NMR systems of more than about 10 spins are currently computationally intractable – a major limitation, particularly in biomolecular NMR spectroscopy.

Our published preliminary work indicates that a polynomially scaling algorithm can be obtained (and accurate simulations performed for large numbers of coupled spins) if certain transformations are applied to the quantum state space of the systems in question. Specifically, it appears that large numbers of quantum states can be dropped or treated approximately. In transformed state spaces, spin dynamics simulations scale polynomially.

It is likely that the successful student will make a major contribution to Magnetic Resonance by exploring and developing the (hitherto unavailable) efficient simulation methods for large spin systems.

Our group has long-standing collaborations with Theoretical Chemistry and Biological NMR and EPR groups at the Universities of Durham, Cambridge, London and a number of international research centres. Supercomputer time will be provided by the Oxford Supercomputing Centre.

The studentship is fully funded (at EU fees level - overseas candidates will need supplementary funding) for 4 years from 1st October 2010. The studentship includes a stipend of £13290 per year. The successful candidate will be provided with a workstation built to his/her specification.

Candidates must satisfy the usual Oxford University requirements for studying for a doctorate. In addition, the student should be skilled in theoretical chemistry and magnetic resonance and must have good writing, communication, presentation, and organization skills. Good programming and systems-building skills count as additional qualification, given that, based on the theoretical results of this project, software systems will be built.

Applications should be submitted online by the deadline of 12 March 2010:

http://www.ox.ac.uk/admissions/postgraduate_courses/index.html

For informal enquiries, please email Dr Ilya Kuprov (ilya.kuprov@oerc.ox.ac.uk).