Mittwoch, 31. Oktober 2007

Position in Illinois

Dear Colleagues,

The University of Illinois at Urbana-Champaign currently has an
opening for a Ph.D.-level spectroscopist in the School of Chemical
Sciences NMR Facility. Primary responsibilities are support of solid-
state NMR, instrument maintenance and repair, and interacting with
researchers on issues of experiment selection and data analysis.

The full ad is posted at

The formal application deadline is November 5.

We would appreciate your bringing this to the attention of qualified
graduate students and postdoctoral associates who are seeking
permanent employment.

Thank you.

Chad M. Rienstra
Assistant Professor of Chemistry
University of Illinois at Urbana-Champaign
600 South Mathews Avenue, Box 50-6
Urbana, IL 61801

Phone: 217 244-4655, Fax: 217 244-3186
Office: A120 CLSL, Lab: A125 CLSL

Donnerstag, 25. Oktober 2007

Postdoctoral Position

Postdoctoral Position: Development of Novel Sample Media for Membrane Protein Structural Biology

The lab of Chuck Sanders at Vanderbilt University has an opening for a postdoctoral fellow to develop and test novel detergents and other membrane-mimetic medium as a means to facilitate membrane protein structural biology using NMR spectroscopy and/or X-ray crystallography. While this project has the potential to proceed to actual membrane protein structural determination it is expected that the first year of the project will be almost exclusively "wet lab" in nature, involving the testing and characterization of new media using a panel of test membrane proteins. The test protein set will include G protein-coupled receptors. This project represents an opportunity to obtain advanced training in practical methods for producing, purifying, reconstituting, and characterizing integral membrane proteins. Such skills are, arguably, just as important in membrane protein structural biology as the actual biophysical methods used to characterize protein structure and so this might be a good opportunity for an NMR expert who wants to expand her/his scientific horizon.

Candidates should be available to start a new position on or before January 1, 2008 and should send a curriculum vita, including contact information for references to:

Prof. Charles Sanders, Dept. of Biochemistry
Vanderbilt University Center for Structural Biology
Nashville, Tennessee 37232-8725 USA
Phone: (615)-936-3756

Lab web site:

Vanderbilt University is an equal opportunity employer.

Postdoctoral Position - Marseille

Postdoctoral Position
Center for Magnetic Resonance in Biology and Medicine (CRMBM),
University of the Mediterranea, Marseille, France
The Center for Magnetic Resonance in Biology and Medicine (Centre de Résonance
Magnétique Biologique et Médicale : CRMBM), located at the University Hospital of la
Timone in Marseille (Director: P.J. Cozzone) is offering a post-doc position (18-24 months)starting January-May 2008. The position is in the "Muscle Group" headed by D. Bendahan and is funded by the ANR (National Agency for Research).
The CRMBM is located on the Campus of the Medical School in Marseille, adjacent to the University Hospital of la Timone, the largest medical facility in Southern Europe. It is jointly operated and funded by CNRS (National Center for Scientific Research), University of the Mediterranea and the Public Hospital System of Marseille.
The research project is devoted to the role of uncoupling proteins (UCP3) in skeletal muscle energetics. Several experimental measurements are planned including muscle energy metabolism, muscle performance, whole body fatty acid metabolism, UCP3 gene expression and mitochondrial electron chain transport.
Experiments will be conducted in UCP3-knockout mice and in rats chemically treated in order to reduce UCP3 expression. Muscle function will be studied strictly noninvasively in a 4.7 T Bruker Avance MR system, using 31P-MRS, MRI and measurements of muscle performance.
Whole body fatty acid metabolism will be investigated through measurements of body fat accumulation using MRI and plasmatic level of free fatty acid. Expression of UCP3 gene will be evaluated using quantitative real-time RT-PCR analysis. Mitochondrial electron chain transport activity will be measured using oxygraphy in biopsy samples.
This multiparametric study will give major information related to the control of energy expenditure in relation to UCP3 expression. Future potential applications related to body weight maintenance might be developed.
The successful applicant should have experience in muscle research preferably with MR
techniques. Applicants should send a Statement of Research Interests, a Curriculum Vitae, and 3 references to :
D. Bendahan
Centre de Resonance Magnetique Biologique et Medicale
Faculte de Medecine de la Timone
27, Bd Jean Moulin
13005 Marseille

Dienstag, 23. Oktober 2007

Postdoctoral and PhD Student Position, University of Basel

Postdoctoral and PhD Student Position
University of Basel

A postdoctoral and a PhD student position are available in the group of Dr. Stephan Grzesiek at the Biozentrum Basel.

We are interested in the application and development of modern NMR methods for obtaining structure/function information on proteins and their complexes. One of our projects focuses on structural studies of HIV entry into T-cells. Facilities include fully equipped 800 MHz (cryo) and 600 MHz high-resolution spectrometers as well as a protein expression lab.

Highly motivated candidates with experience in macromolecular NMR, method development for solution or solid state NMR, membrane biophysics, molecular biology or protein chemistry with a background in structure should e-mail their application including CV and the name of the two references to:

Prof. Stephan Grzesiek
Biozentrum, University of Basel
Klingelbergstrasse 70
CH-4056 Basel, Switzerland

Freitag, 19. Oktober 2007

NYU Faculty Position, Biophysical chemistry

Dear Colleagues,
NYU is searching to fill a faculty position in biophysical chemistry, broadly defined. Biophysical NMR spectroscopy is an option greatly favored. I would therefore be grateful if you could pass on the attached announcement to potentially interested
candidates. The ad is currently running in several publications. For junior candidates, I also recommend arranging for reference letters, even though the ad says only to list names. This would facilitate the process due to the late deadline. As mentioned in the ad, we would also consider senior applicants for this position and would welcome your suggestions.
Thank you very much
Alexej Jerschow

junior or senior

The Department of Chemistry at New York University, located in Greenwich Village in lower Manhattan, invites applications for a faculty position in experimental biophysical chemistry. Strong candidates in other fields of experimental chemistry will also be considered, especially in areas of nanoscience and materials chemistry. The appointment will begin in the Fall of 2008, pending final administrative and budgetary approval.

All ranks will be considered, but applications from junior faculty candidates are preferred. The Department is embarking on a significant growth plan that includes the creation of the Molecular Design Institute, the recent hire of two senior-level faculty with more anticipated, and expansion of laboratory and instrumentation facilities. Applicants should have a very strong research record and a commitment to teaching. Applications should include a curriculum vita, a list of publications, a statement of future original research and teaching plans, and the names of at least three references. Application review will begin on November 15, 2007. Therefore, to guarantee full consideration complete applications should be sent by this date to

Faculty Search Committee
Department of Chemistry, New York University
100 Washington Square East, New York, NY 10003

NYU encourages applications from women and members of minority groups.

Postdoc in Maryland

Postdoctoral Position
University of Maryland

Postdoctoral position is available immediately in the group of
Dr. Vitali Tugarinov at the Dept. of Chemistry & Biochemistry,
University of Maryland, College Park

Candidates should preferably have experience in one or several of the
following areas: biomolecular NMR spectroscopy, protein NMR methodology,
protein (bio)chemistry, molecular modeling/structure calculations.

The dedicated biomolecular NMR facility in the Center of Biomolecular
Structure and Organization features two 600 MHz instruments (one
cryo-probed) and the adjacent laboratory is fully equipped for protein
expression and sample preparation. Access to higher field instrumentation
at nearby universities is possible. University of Maryland-CP is situated
in close proximity to Washington, D.C., Baltimore, and Maryland's I-270
Technology Corridor with an easy access to vast research resources and
facilities, including those of the NIH, FDA, USDA and NIST.

Applicants may e-mail their CV to or call 301-405-1504.

Freitag, 12. Oktober 2007

Assistant/Associate Professor

Assistant/Associate Professor:

Conservation Science, Spectroscopy/NMR

The Department of Mathematics and Science at Pratt Institute is looking for a scientist to fill a tenure track position at Assistant or Associate Professor level begining in the Fall 2008. The successful candidate should hold a Ph.D in Chemistry, Physics or Materials Science and should have a strong interest in contributing to an expanding collaborative research and teaching program in the Science of Art Conservation (Conservation Science) funded, in part, by the Alfred P. Sloan Foundation. The candidate is expected to teach and develop new courses in his/her field of expertise as it applies to Art, Design, and/or Art Conservation and to participate in research projects in the area of Conservation Science. Experience in NMR and/or Conservation Science in a museum setting is a plus. For more information, please contact Prof. Eleonora Del Federico,

Mittwoch, 10. Oktober 2007


New York University

We are looking to fill a postdoctoral position starting January 2008 (or later) on
technique development in 23Na NMR/MRI and 1H CEST NMR/MRI at New
York University. The ideal candidate will have experience in NMR theory
and experimental work. Experience with solid-state NMR, MRI, Diffusion
NMR, quadrupolar NMR, programming will be of advantage, although are
not requirements. The postdoc will be able to acquire experience working
with high-field MRI scanners (7T) at the Center for Biomedical Imaging.
New York University’s Chemistry Department is located at the heart of
Manhattan in Greenwich Village. The project will be performed jointly
between the NYU Chemistry Department (A. Jerschow) and the NYU
School of Medicine (R. R. Regatte).

The initial appointment is for 1.5 years, with possible extension. Applicants
should send their application including CV, a publication list, and names
and contact information of two references who would be willing to comment
on their work to alexej.jerschow at

Dr. Alexej Jerschow
Chemistry Department
New York University
100 Washington Square East
New York, NY 10003
alexej.jerschow at

Freitag, 5. Oktober 2007

PhD or PostDoc in Nijmegen

Reference Hyph-07:
PhD (4-years) or PostDoc (3.5-years) in the Department of Physical Chemistry / Biophysical Chemistry of the Radboud University (Nijmegen, The Netherlands).
Position description:
Collaborative research project with Industrial partners, concerning the development of NMR-based analytical methods aiming at the full structure characterization and absolute quantification of small organic molecules from/in complex mixtures (such as fermentation products, lysates, body-fluids, food matrices...). Full integration of “all possible” analytical data (spectrometric, spectroscopic, and chromatographic) will be investigated in order to reach unambiguous identification / characterization of a compound without prior knowledge of its structure or origin.
Candidate profile:
The ambitious academic candidate (m/f) would have a chemistry/analytical chemistry degree (and/or PhD in the same field) with a significant background / experience in NMR (Bruker) and other additional analytical methods (MS, LC-MS, UV, IR). Knowledge / expertise in separation methods and/or hyphenated analytical methods will be appreciated. The candidate should be interested in applied science and technological aspects, efficient in teamwork, have broad scientific interest with good communication ability (oral / writing).
For PhD the position is four year maximum. At first instance, appointments are for one year. After a positive evaluation prolongation with three years is affected. A Dutch Ph.D.-program is four years, at the end of which the appointment should finish with a Ph.D.-thesis and a Ph.D.-degree. For Ph.D., gross salary amounts to Euro 1.958 per month in the first year, and increases to Euro 2.502 per month in the fourth year. For a post-doc salary is according to experience and set by University regulations
Further information and application:
The position will be opened at the Radboud University (Nijmegen, the Netherlands) and is co-financed by the company Spinnovation ( ). When applying for a Ph.D., the position will be full-time over a 4-years period. When applying for a Postdoc, the position would be part-time 4 days per week over 4 years, or full-time over 3.5 years. The candidate must be fluent in English. Application shall be sent in English, mentioning the position reference ref. Hyph-07, including CV, accompanying letter and names and addresses of two reference persons who can be contacted.

Applications to be sent to: Prof.Dr. S. Wijmenga (Biophysical Chemistry). Email: ; Websites:, .

Dienstag, 2. Oktober 2007

Postdoctoral Position in Solid State NMR at CEA Saclay

Postdoctoral Position in Solid State NMR at CEA Saclay (20 km S-W from

Tritium solid-state NMR: Towards long-range distance measurements in
biological complexes

This position is funded by the National Agency for Research
(ANR) for a project entitled "Long range distance measurement by solid
state tritium NMR. Observing the structure and dynamics of biological
complex systems at work". The aim of this project is to develop a new
approach for measuring long-range inter-atomic distances in tritium
labeled systems. This is a collaborative project with chemists having an
expertise in tritium labeling and biochemists. 3H MAS NMR is offering
many exciting new perspectives for biological NMR methods as well as
many methodological developments are envisaged.

In a first step, long range distance measurements will be validated on
deuterated and protonated model compounds, with isolated 3H-3H spin
pairs whose distance will range from 6A to 15A. This step will require
an investigation of different recoupling techniques, as well as some
methodological work on specific recoupling schemes if necessary. In a
second step, the technique will be applied to important issues in
structural biochemistry.

First results have been presented at the 5th Alpine Conference on NMR

This is a one-year post-doctoral position available starting at January
2008. Extension to two years is possible.

Our lab is equipped with three NMR spectrometers, 500 NB (with micro
imaging, gas and hyperpolarized xenon NMR facilities), 300 WB and 500 WB
Bruker Avance II spectrometers.

Postdoctoral salary will be around 2000/2500 Euro per month.

Applicants are invited to send a curriculum vitae and a brief statement
of research along with letters of reference to:

Thibault Charpentier
LSDRM - Service de Chimie Moléculaire
CEA Saclay
91191 Gif-sur-Yvette, FRANCE.

For further details, you are welcome to contact Thibault Charpentier, or Patrick Berthault,

Thibault Charpentier
Laboratoire de Structure et Dynamique par Résonance Magnétique Laboratoire Claude Fréjacques - CEA/CNRS URA 331 DSM/DRECAM/SCM - Bât 125 CEA Saclay 91191 Gif-sur-Yvette cedex, FRANCE
Tél: (33) 1 69 08 23 56 / 82 75 Fax: (33) 1 69 08 66 40

To Whom It May Concern

Craig F. Wilson, B.Sc. (Hons.), M.Sc.
92 Holwell, Lister Hospital Residences
Coreys Mill Lane
Tel: +44 (0)7772 012 547
26th September 2007

To Whom It May Concern,
I attach my resume for your perusal and for
you to read through at your own convenience. This is to enquire into
possible Ph.D. positions and hope that you will consider my experience
in this field.

I have 3 3/4 years of postgraduate research experience in Organic
Chemistry, NMR and Molecular Modelling from the School of Chemistry,
University of St. Andrews, Fife, Scotland, U.K. and the Institute of
Pharmaceutical Chemistry, Szeged University, Hungary. I have an M.Sc. in
Biological and Medicinal Chemistry from the University of St. Andrews, Fife,
Scotland, U.K. and a B.Sc. (Hons.) in Chemistry and Business Studies from
the University of East Anglia, Norwich, U.K. I have 1 1/4 years of related
work experience in academia and industry; academic as a postdoctorate
research assistant for the School of Biological and Chemical Sciences,
Birkbeck College, University of London, London, U.K.; industrial as a
technical chemist in paints and polymers, aviation chemistry and waste
treatment research and development.

Projects I have been involved in have been:

Ph.D. studies
i) Aggregation in the Aminop henols by 2DNMR

Postdoctorate studies
ii) Improved Damage Assessment of Parchments (IDAP)
iii) Monitoring in Damaged Historical Tapestries (MODHT)
iv) Micro-Climate Monitoring In Cultural Heritage Preservation (MIMIC)

Ph.D. studies
v) A Study of Conformational Analysis and Molecular Dynamics by NMR
- NH-OH Hydrogen Bonding, Dynamics and Exchange
- Solution 2DNMR and Conformational Analysis of Narasin Alkali Metal

M.Sc. studies
vi) Solution 2DNMR and Conformational Analysis of Monensin-A Alkali Metal

I look to you for you thoughts and ideas to my suitability for the above
position. If you have any questions please do not hesitate to contact me.

I look forward to hearing from you.

Yours sincerely

Craig F. Wilson, B.Sc. (Hons.), M.Sc., MRSC