Postdoctoral Position: Development of Novel Sample Media for Membrane Protein Structural Biology
The lab of Chuck Sanders at Vanderbilt University has an opening for a postdoctoral fellow to develop and test novel detergents and other membrane-mimetic medium as a means to facilitate membrane protein structural biology using NMR spectroscopy and/or X-ray crystallography. While this project has the potential to proceed to actual membrane protein structural determination it is expected that the first year of the project will be almost exclusively "wet lab" in nature, involving the testing and characterization of new media using a panel of test membrane proteins. The test protein set will include G protein-coupled receptors. This project represents an opportunity to obtain advanced training in practical methods for producing, purifying, reconstituting, and characterizing integral membrane proteins. Such skills are, arguably, just as important in membrane protein structural biology as the actual biophysical methods used to characterize protein structure and so this might be a good opportunity for an NMR expert who wants to expand her/his scientific horizon.
Candidates should be available to start a new position on or before January 1, 2008 and should send a curriculum vita, including contact information for references to:
Prof. Charles Sanders, Dept. of Biochemistry
Vanderbilt University Center for Structural Biology
Nashville, Tennessee 37232-8725 USA
Lab web site: http://structbio.vanderbilt.edu/sanders
Vanderbilt University is an equal opportunity employer.