Montag, 21. November 2011


We are looking for a young, open-minded, enthusiastic, committed and diligent individual with a background in chemistry, physics or material-sciences (German Diploma/MSc equivalent).
The successful candidate will work on the multi nuclear solid state NMR characterization of immobilized catalysts, metal-clusters, metal-nanoparticles and their interactions with substrates. The immobilized catalysts are made in-house by covalently binding metal-containing catalysts to the surface of nano-structured silica materials with different morphologies (porous or nanoparticles) via organic linkers or obtained by a cooperating group at the CNRS-Toulouse.

The structure of the immobilized catalysts on the support material, its interactions with substrates and the influence of macroscopic parameters such as temperature on its properties are investigated. The catalytic activity of the catalysts is tested by model reactions, in particular hydrogenations.
Previous hands-on experience with solid state NMR or heterogeneous catalysis will be helpful, but is not necessary.

We offer a state-of-the-art research infrastructure including solid-state NMR (600, 500 400 and 300 MHz) spectrometers and a wet-chemistry lab including GC, HPLC, UV/Vis and other techniques. An additional 400MHz DNP-NMR solid state NMR spectrometer will be installed at the end of 2012.

The NMR lab is headed by an academic staff scientist, who provides user support. The group is part of the research group FOR-1583, the research network SFB 598, the LOEWE-research group SOFT-CONTROL and various national and international cooperation projects. The group is located at the Campus Lichtwiese of the Technical University Darmstadt.
Enquiries and applications shall be addressed to Gerd Buntkowsky (gerd.buntkowsky at

Prof. Dr. Gerd Buntkowsky
Physikalische Chemie der kondensierten Materie
Technische Universität Darmstadt
Eduard-Zintl-Institut für Anorganische und Physikalische Chemie
Petersenstr. 20, D-64287 Darmstadt
phone : +49 6151/16-2607 fax: +49 6151/16-4347

email :
Research :

Postdoctoral position at St. Jude

Dear colleagues,

a postdoctoral position is available immediately in my lab at St. Jude Children's Research Hospital in Memphis, TN, for a candidate motivated to pursue structure/function relationships of highly dynamic protein complexes in the ubiquitin pathway. The project focuses on the recognition of highly flexible proto-oncogenes by their cognate ubiquitin ligases and how dynamic interconversion of multiple bound states relates to function in health and disease. The successful candidate will use NMR spectroscopy, other biophysical and biochemical techniques to dissect the binding mechanism and establish structure/function relationships.

This position is an ideal opportunity for either (1) an experienced NMR spectroscopist who would like to complement his or her expertise with other, diverse tools for understanding protein complex function and mechanism, or (2) for an enzymologist/biophysicist interested in structural biology of dynamic protein complexes. The fellow would benefit from both the outstanding environment in the lab and the highly collaborative St. Jude community.

Candidates should have recently earned/expect to earn a Ph.D. in a related field, and should have experience in protein biochemistry, enzymology, biophysics, or NMR spectroscopy.

Supplemental Application Requirements
Mail Postdoc Application: No
Letter of Interest Required: No
Curriculum Vitae Required: Yes
Description of Research Interest Required: Yes
3 Letters of Recommendation Required: Yes
Outline of Past Accomplishments Required: No
Outline of Career Aspirations Required: No

For the add please see

Please send a CV and a brief description of research and career goals and arrange to have three letters of recommendation sent to

Tanja Mittag, PhD
Assistant Member
Structural Biology
St. Jude Children's Research Hospital
262 Danny Thomas Place, MS 311
Danny Thomas Research Center, Room D1034F Memphis, TN 38105
office: (901) 595-6261
lab: (901) 595-6182

Montag, 8. August 2011

Ph.D. Position

Ph.D. Position
Myelin Water Imaging
Institute of Neuroscience and Medicine (INM-4)
Research Centre Juelich, Juelich, Germany

This position is primarily aimed at the development and application of myelin water mapping in the human brain in vivo using different relaxometric modalities.
The Research Centre Juelich ( is one of Europe's largest interdisciplinary research centres with 4,600 employes, 7 research institutes with 46 divisions. The Institute of Medicine and Neuroscience INM-4 (Medical Imaging Physics offers a highly interdisciplinary environment with physicists, engineers and neuroscientists working on a better understanding of the brain with the help of advanced brain imaging methods and state of the art technology. Among others, a unique 9.4T combined MR-PET scanner offers unprecedented research opportunities.
We are interested in an individual with a solid physics background documented by outstanding academic performance and advanced computer programming skills. The work will involve developing protocols suited for myelin water fraction and absolute water content imaging in vivo at different field strengths; comparing the water pools revealed by the different relaxometric modalities; implementation of new imaging methods; advanced data processing techniques; comparison with other MR modalities, e.g. diffusion. The available instrumentation includes several human scanners, such as a 3T Siemens Trio and a combined 3T MR-PET Siemens scanner, 4T Bruker/Siemens system, 9.4T MR-PET Siemens system as well as a 9.4T home-built animal scanner based on Siemens and Varian consoles. There are also extensive facilities for all aspects of MRI hardware development and data analysis.

Interested persons should email a Curriculum Vitae including name, address and email address of at least one reference to:

Dr. Ana-Maria Oros-Peusquens
Institute of Neuroscience and Medicine (INM-4)
Research Centre Juelich
Leo-Brandt-Str, 52428 Juelich
tel.: +49-2461 61 2107
fax: +49-2461 61 2820



The NMR and Structure Analysis unit of the Department of Organic Chemistry of Gent University (Belgium) is involved in research activities in the (bio)chemical and material sciences using NMR spectroscopy as the main investigative tool. With four fully equipped Bruker NMR spectrometers, it is the main academic NMR facility active in the chemical and material sciences in Belgium. The equipment inclides an AVANCE–II 700 MHz instrument, housed within the unit and part of the Interuniversitary NMR Facility jointly operated between Ghent University, the Vrije Universiteit Brussel (VUB) and Antwerp University (UA), as well as an Avance-III 500 MHz (in installation), an AVANCE-II 500 MHz and an AVANCE 300 MHz. Equipment includes three- and four-channel setups, hrMAS at 700 MHz and a high gradient amplitude diffusion probe (1600 T/m) at 500 MHz.

A three year, University funded postdoctoral position is available starting preferably before January 1st 2012 (negotiable), to further develop and implement techniques and methodologies for the solution NMR based investigation in the following projects:

· The characterization of the impact of chemically modified nucleosides on the structure and dynamics of DNA duplexes intended to mimic protein active sites. This involves the use of both unlabelled and selectively labeled DNA systems.

· In situ characterization of colloidal dispersions ranging from quantum dots and rods to pigment and latex particles – this also involves methodological developments in diffusion respectively STD NMR spectroscopy.

The duties of the successful applicant include:

Scientific research within the context of one of the above research projects.
Scientific involvement (including co-authorship) in short term research projects with external partners.
Scientific support and co-manager of the Interuniversity 700 MHz high field NMR facility and the new 500 MHz facility within the department.
Mentoring of Master and PhD students.
Contribute to the educational activities of the department.

We offer:

The opportunity to fully participate in our current research projects, within the best equipped NMR facility in the country.
The opportunity to develop a proper research interest, i.e. based on the applicants own interest.
A competitive salary amounting to 1800-2100 €/month (commensurate with age and experience).

To be eligible, applicants should:
Demonstrate knowledge and practical expertise in solution NMR spectroscopy, as demonstrated by publications in international journals and/or oral communications at national or international meetings.
Demonstrate technical knowledge in the operation of NMR equipment (hardware and software) including implementation of pulse sequences.
Demonstrate interest for MSc student mentoring
Have acquired a PhD degree by the time of appointment (foreseen 1/1/2012).

The Universiteit Gent is an equal opportunity employer. Ghent is a pleseant city with medieval centre and good quality of living
For further information contact Prof. José C. Martins via e-mail:
Ghent University:
City of Ghent:

PhD students and postdocs positions

PhD students and postdocs positions on new applications of NMR in environmental sciences

Short description of projects:
Project1: Use high-resolution NMR to measure intramolecular variation of the heavy hydrogen isotope deuterium in historical plant samples, to link past climate with physiological changes, and to define plant-climate interactions relevant for future plant productivity.
Project2: Apply quantitative 13C NMR to primary metabolites and to tree rings, to establish links between intramolecular 13C variation and partitioning of metabolites in plants.
Project3: NMR Characterization of Soil Phosphorus and Carbon Forms during Long Term Succession
We look for highly creative students seeking a career in interdisciplinary research at the interface between chemistry, biology and earth sciences. Applicants should have a university education in chemistry, biochemistry, or equivalent. Experience in NMR, stable isotopes or plant physiology is of advantage.
For project details and applications (including cover letter describing your motivation for this position, CV including a list of university courses with grades, a copy of your graduate work, and names and addresses of two persons willing to act as references), please contact Prof. Jürgen Schleucher,

Donnerstag, 4. August 2011

Research Scientist, Solid State NMR Spectroscopy

A full time position is available for an experienced research scientist with skills in solid state NMR spectroscopy. This is a leading role in the University-wide NMR Facility, which has recently implemented ARC funding for a major initiative in solid-state NMR spectroscopy.
The appointee will consolidate advanced solid state NMR spectroscopic techniques to enable research in the areas of molecular & life sciences, medicine, materials engineering and polymers within UNSW and with partner organisations, as well as train research staff and students in this area of specialization.
This is a fixed term, full time position for a period of three years. Salary Level A (Completed PhD): A$74,129 - A$79,288 per year (plus 17% employer superannuation and leave loading). Applications close: 22/08/2011

See the full description and how to apply at #8145.

Location: NMR Facility, University of NSW, Sydney, Australia; see

Contact the manager, Dr. James Hook for further information; email:

Research Fellow (Postdoc) in Solid State NMR

A full-time position is available at the Institute of Solid State Physics of the Technical University Darmstadt, Germany (Group of Prof. M. Vogel).

The successful applicant is an experienced scientist in the field of solid state NMR. He or she has a consolidated knowledge of 1D and 2D NMR studies on dynamics and structure of disordered solids, profound skills in the operation, maintenance, and development of NMR equipment, and experience in simulation of NMR data.

The responsibilities associated with this position include:

- Management and maintenance of the NMR facility featuring, among others, spectrometers for MAS, NMR diffusometry (SFG and PFG), and NMR relaxometry

- Own research activities in the field of molecular dynamics in disordered materials, including complex fluids in nanoporous materials, weakly hydrated proteins, and lithium ion conductors

- Training of PhD, master, and bachelor students

The position is for 2 years with a possible extension to up to 5 years

Additional information about our research activities can be found on our websites:

Applications should be submitted until 01 September 2011 to:

Prof. Dr. Michael Vogel
Institut für Festkörperphysik
Technische Universität Darmstadt
Hochschulstr. 6
64289 Darmstadt, Germany

PhD position Leiden University

The Solid State NMR group at the Leiden Institute of Chemistry, Leiden
University has a PhD studentship (38 hrs a week) available in the Modular
Design of a Bio-Inspired Tandem Cell for Direct Solar-to-Fuel Conversion.

Apply before august 21, 2011.

Project description
The successful candidate will participate in the SOLARFUELTANDEM
collaborative research project (CPR) of the European Science Foundation
Eurocores programme EUROSOLARFUELS. The principle objective of this
collaborative project, shared between its 10 European contributors, is the
modular design of a bio-inspired nanostructured organic-inorganic
heterojunction tandem cell for solar to fuel conversion. The vision is to
work from a combination of natural and artificial modules for catalysis and
charge separation and explore a range of different combinations for
functional tandem device concepts. This allows the consortium to work in
parallel on modular systems integration and optimization of components.
Self-assembled Zn chlorin nanocylinders forming excitations with internal
charge transfer character will be aligned in an alumina solid membrane to
form a supramolecular sensitizer for ultrafast charge separation and charge
injection into a low-bandgap Si semiconductor. In this heterojunction
system, two regions of the solar spectrum can be used in tandem to overcome
the thermodynamic barrier for water oxidation and hydrogen production with
visible light in a single device. Two complementary synthetic strategies
will ensure access to a wide library of Zn chlorins. Post-functionalization
of Chl a and BChl c will ensure rapid preparation of compounds for
self-assembly and photophysical studies, also with 13C labels. Total
synthesis will give full control over the pattern of substituents for
fine-tuning of all required physicochemical properties. We will use most
sturdy natural PS2 and Pt modified PS1 systems from C. merolae with a very
high photosynthesis rate as working photocatalysts for optimization of
catalyst interfacing to semiconductors. In a parallel supramolecular
approach we will prepare homogenous Ru/Ir/Co water oxidation and Fe/Ni/Co
hydrogen formation catalysts for immobilization and interfacing to natural
and artificial electron transfer units. Optical spectroscopy, NMR, EPR,
electrochemistry, X-ray crystallography and modeling will be used in the
partnership to assess the kinetics of the multi-electron catalysis and dual
band gap electron transfer mechanisms to guide the design. The final aim of
the CPR is to give proof of principle of a functional tandem device. The PhD
student will primarily contribute to the CPR with structure-determination
and structure-function studies of chlorosome-type supramolecular dye
sensitizers. This contribution to the project will be considered a success
if he or she can guide the design of the chlorosome cylindrical rods into an
operational functional supramolecular dye sensitizer for application in an
artificial reaction center concept.

See also:
Ganapathy S et al. (2009) Zinc chlorins for artificial light-harvesting
self-assemble into antiparallel stacks forming a microcrystalline
solid-state material. Proceedings of the National Academy of Sciences
Ganapathy S et al. (2009) Alternating syn-anti bacteriochlorophylls form
concentric helical nanotubes in chlorosomes. Proceedings of the National
Academy of Sciences 106:8525­8530.

You will be employed for a period of maximally 4 years, which is expected to
lead to the completion of a Ph.D. thesis. Appointment will be through the
Organization for Fundamental Research of Matter (FOM).
An appointment with FOM includes a pension build-up and facilitates other
benefits such as an annual holiday premium.
All our PhD students are embedded in the Leiden University Graduate School
of Science ( and in the Research School
The Leiden Institute of Chemistry (LIC). Our graduate school offers several
PhD training courses at three levels: professional courses, skills training
and personal effectiveness. In addition, advanced courses to deepen
scientific knowledge are offered by the research school. This guarantees a
challenging environment to develop on-the-job the skills and academic

Further information:
You will be supervised by Prof. Dr. H.J.M. de Groot
( For more information please contact this email

Qualified applicants are invited to submit their application before August
21, 2011. They should include a letter of interest, a full curriculum vitae,
and names and email addresses of two references and sent to with subject FOM-Solarfueltandem.

Postdoctoral position at the IRB Barcelona

The Laboratory of Molecular Biophysics at the IRB Barcelona ( offers postdoc positions (starting date 01/01/2012) for development and application of novel computational tools to quantitatively exploit the information contained in high resolution NMR and single molecule techniques. The project aims to characterize the structural heterogeneity and dynamics of multi-domain proteins with intrinsically disordered regions involved in cancer and neurodegenerative diseases.

The laboratory belongs to the Joint BSC-IRB Research Programme in Computational Biology, which provides direct access to the Barcelona Supercomputing Center (Marenostrum). The laboratory has a strong multi-disciplinary and international character.

Previous experimental and/or computational experience in NMR (liquid or solid state), single molecule techniques or molecular simulation (advanced sampling methods) is required.

Interested candidates should send their CV and 2 letters of recommendation to Dr. Xavier Salvatella ( Positions open until filled. Salary negotiable upon experience.

Post Doctoral Position - PET/MRI Applications in Tumor Biology

Post Doctoral Position
PET/MRI Applications in Tumor Biology
Biological Imaging Center
California Institute of Technology

Post Doctoral Position. This position is aimed at development and application of multimodal PET/MRI in small animal models of cancer. The Biological Imaging Center ( and Caltech Brain Imaging Center ( are highly interdisciplinary endeavors with biologists, chemists, physicists, and engineers working on a number of animal models of disease and developmental processes. We are interested in an individual who is firmly grounded in imaging theory and practice with an interest in applications in tumor biology. This work will involve various PET and MR methodologies in rodent model systems; including DTI and DCE MRI, as well as simultaneous µPET imaging with both small molecule and antibody tracers. Small animal MRI facilities at Caltech include a 11.7T/89mm scanner and a 7T/30cm scanner with µPET insert. There are also extensive facilities for all aspects of MRI hardware development and data analysis.

Interested persons should email or mail a biosketch including names, addresses, & email addresses of three references to:

Russell E. Jacobs, PhD
m/c 139-74 Caltech
1200 E. California Blvd
Pasadena, CA 91125-7400

Postdoctoral position in NMR and biomaterials science.

A postdoctoral position is available for research in the area of interactions and dynamics of the nuclear pore complex (NPC), the sole mediator and gatekeeper for trafficking between the nucleus and cytoplasm. Our studies use advanced biophysical and structural methodologies, in particular various NMR techniques applied in vitro and in vivo, to characterize the dynamic atomic-scale behavior of the components of this macromolecular gating system. This work will also seek to further refine our nanoscale artificial mimic that faithfully reproduces key features of trafficking through the NPC, including transport-factor mediated cargo import (1). Such NPC-inspired molecular sorters could have many practical analytical and preparative applications.

Interested candidates should have a strong background in one or more of the following areas: multidimensional NMR (liquids or solids), protein expressions methods, materials science, and computer simulations of molecular structure, and have completed their Ph.D.

This project is a collaboration between the NPC research focused groups of Prof. Michael Rout and of Prof. Brian Chait at Rockefeller University, and the NMR-focused lab of Prof. David Cowburn at Albert Einstein College of Medicine. NMR facilities include twelve spectrometers located at the two Universities and at the New York Structural Biology Center ranging from 500-900 MHz, and including solid state systems, with an additional DNP-solids system expected in 1q 2013. There are extensive facilities in the labs and in central resources for protein production, mass spec, and high performance computing.

The position is available immediately, and interested candidates should forward the biographical sketches including the names of three references to Beth Anne Hatton;; Administrative Assistant.

The Rockefeller University and Albert Einstein College of Medicine are an Affirmative Action/Equal Opportunity/VEVRAA employers and solicits applications from women and under-represented minorities.

(1) Jovanovic-Talisman, T., Tetenbaum-Novatt, J., McKenney, A.S., Zilman, A., Peters, R., Rout, M.P., and Chait, B.T. (2009). Artificial nanopores that mimic the transport selectivity of the nuclear pore complex. Nature 457, 1023-1027.

Mittwoch, 20. Juli 2011

facility manager

A facility manager position is available in the Chemistry department of the Heinrich-Heine Universität Düsseldorf starting from September 1, 2011.

The responsibilities associated with this position will be:
Management of the NMR facility and organization of the NMR service.
Support of research and administrative tasks.
Teaching and training of Bachelor-, Master- and PhD students.

The successful applicant has a profound knowledge of 1D, 2D and 3D homo- and heteronuclear NMR spectroscopy, practical experience in the operation and maintainance of Bruker spectrometers, skills in managing a service-oriented NMR facility, and is able to find practical solutions to spectroscopic problems, including the investigation of kinetics and dynamics and simulation of higher order spectra.

The position is initially limited to two years with the possibility of turning into a permanent position.

Scientific qualification (Habilitation) is not possible.

Further information (in German):

For application please contact:

Prof. Dr.
Christoph Janiak
Institut für Anorganische Chemie und
Universität Düsseldorf
Universitätsstr. 1

Forschungszentrum Juelich GmbH
52425 Juelich
Sitz der Gesellschaft: Juelich
Eingetragen im Handelsregister des Amtsgerichts Dueren Nr. HR B 3498
Vorsitzender des Aufsichtsrats: MinDirig Dr. Karl Eugen Huthmacher
Geschaeftsfuehrung: Prof. Dr. Achim Bachem (Vorsitzender),
Dr. Ulrich Krafft (stellv. Vorsitzender), Prof. Dr.-Ing. Harald Bolt,
Prof. Dr. Sebastian M. Schmidt

Besuchen Sie uns auf unserem neuen Webauftritt unter

PhD position

A PhD position is available at the Freie Universität Berlin, Department of Biochemistry to analyse HLA-DM catalyzed peptide loading of MHC class II proteins by NMR spectroscopy and other biophysical methods.

Nascent MHC II proteins are preloaded with self-peptides. In the endolysosomal compartment the exchange of the self-peptide for higher affine antigenic peptide is catalyzed by the MHC-like molecule HLA-DM. This leads to immunogenic MHC II-peptide complexes that are presented on the cell surface for T-cell recognition.

Within an interdisciplinary team including immunologists, crystallographers and molecular modellers we gained critical insights into MHC peptide loading by biochemical and spectroscopical analysis of the reaction over the past years (Günther et al., PNAS 2010; Schlundt et al., Angewandte Chemie 2009), however the precise mode of action of the HLA-DM catalyzed peptide exchange is still missing. Your task will be to target the mechanism of HLA-DM catalysis. This involves the expression and purification of MHC class II proteins (a heterodimer of ~46kD) based on working protocols integrating different labeling schemes for NMR analysis. The high molecular weight and seemingly short half-live of the MHC II - HLA-DM complex is likely to involve the design and purification of modified constructs as well as more sophisticated NMR methods including H/D exchange and relaxation dispersion experiments.

We are looking for candidates with a strong interest in structural biology and ideally with experience in protein purification and a basic knowledge of protein NMR spectroscopy.

Funding is available for a minimum of three years.

For application please contact:

Prof. Dr. Christian Freund
Freie Universität Berlin
Thielallee 63
14195 Berlin or


Structural studies of Vpx, the accessory protein of the HIV-2

We are looking for a candidate to apply for a 2 years postdoctoral position in
the Laboratory of Biological NMR and Crystallography at the University Paris
Descartes. The project will aim to determine the structure of the Vpx protein
(112 amino acids) and of its complexes with inhibitors identified after
screening of small compound libraries, using high-field multidimensional NMR
and Molecular Modeling. HIV-2 is the second leading cause of AIDS in humans and
we are interested with the Vpx protein that increases the efficiency of
infection by lentivectors of various origins, allows the transport of viral DNA
to the nucleus and promotes the accumulation of retroviral DNA in some cells of
the immune system. Vpx thus allows viral dissemination but its role in the
replication of HIV-2 and its molecular mechanism are still not understood.

The objectives of this project are to understand at the structural and
mechanistic level, how Vpx inhibits cell defenses against viral infection. We
aim to identify partners of Vpx in cells and to elucidate its exact role in
viral dissemination and its role in the replication of HIV-2. Finally, we want
to understand how cellular factors can modulate the early stages of lentiviral
infection. The obtaining the Vpx protein structure, identification of partners
and the study of their complexes will make our contribution to the
understanding of the mechanisms involved in the various activities of this
protein. The study of the protein Vpx will be greatly simplified by the
experience we have gained from structural and functional studies performed on
the Vpr protein.

The protein Vpx has been obtained by chemical synthesis and will be produced by
overexpression in Coli and 15N labeled. The project will be based on functional
and structural experiments that associate liquid-state Nuclear Magnetic
Resonance and Molecular Modeling. The candidate should have a good experience
in the protein overexpression et their purification in bacterial systems and a
good expertise in multidimensional heteronuclear NMR and molecular modeling.
The starting date is January 2012 for a two years funding. Application, CV and
reference letters should be submitted to:

Dr Serge Bouaziz

Postdoc Position

A 12 months postdoctoral position is opened in the framework of a collaboration between the CNRS/Rhodia joint Research Lab ‘Laboratoire Polymères et Matériaux Avancés’ (LPMA, UMR 5268), Lyon, France, and the CNRS/University Paris-Est Créteil joint Research Lab ‘Institut de Chimie et des Matériaux Paris-Est’ (ICMPE, UMR 7182), Thiais, France. The postdoctoral researcher will develop his/her research activities at ICMPE, Thiais, in the department ‘Systèmes Polymères Complexes’ and will be co-supervised by Cédric Lorthioir (ICMPE) and Paul Sotta (LPMA). Rhodia is a global specialty chemicals manufacturer with 5 multidisciplinary Research & Development Centers worldwide. Lyon is the main Rhodia R&D Center for Europe. CNRS is one of the main governmental research organization in France, involved in all scientific fields.

Partially polar polymers are very sensitive to water. For example a dry semi-crystalline polymer like polyamide (PA) can absorb up to 12 wt% water in saturated humid atmosphere (Relative Humidity = RH 100). The water content drastically affects the glass transition temperature, which may be shifted from 80°C in the dry state down to -10°C in the humid state, and therefore the mechanical and other properties.

The purpose of this work is to combine advanced Solid-State NMR approaches to investigate the molecular dynamics in polyamides. Selective Solid-State NMR experiments, performed as a function of temperature, will allow identifying the specific types of motions corresponding to the various relaxation processes observed in these materials, in the amorphous phase. The mobility and mobility gradients in the amorphous phase located in the vicinity of the crystallites will be characterized by selective excitation of the crystalline signal combined with 1H spin diffusion. Model polyamide materials with a variable, controlled crystallinity will be considered. The dynamics will be studied both in the dry state and in the presence of various amounts of water. These experiments will clarify the mechanisms by which water plasticizes polyamide.

The position is to start any time in 2011. It is opened to an experimental physicist/physico-chemist, with a PhD thesis in the field of polymer physics or chemical physics. An experience in Solid-State NMR, if not mandatory, will be highly appreciated. Gross salary is about 2000 Euros/month. To apply, please send an application letter together with a detailed CV and contact details of two academic referees to either of the following contact persons:

1) Paul Sotta
Laboratoire Polymères et Matériaux Avancés
85, rue des Frères Perret
69192 Saint-Fons Cedex, France

Tel: +33 (0)4 72 89 64 66

2) Cédric Lorthioir
Institut de Chimie et des Matériaux Paris-Est
Equipe ‘Systèmes Polymères Complexes‘
2-8, rue Henri Dunant
94320 Thiais, France

Tel: +33 (0)1 49 78 13 08

Postdoctoral Position in biomolecular SSNMR spectroscopy in Grenoble (France)

The biomolecular NMR group at the Structural Biology Institute (IBS) in
Grenoble is looking for a highly motivated young researcher to join its team as
a post-doctoral researcher on a project funded by the French Research Funding
Agency ANR (project leader Paul Schanda). The project aims at the molecular
level understanding of the function and dynamics of large proteins, as well as
the development of novel solid-state NMR methods for studying dynamics. A
two-year contract is offered.

We are currently studying two biomolecular systems, (i) a large oligomeric
enzymatic assembly of several hundred kDa, and (ii) a membrane protein involved
in the transport of metabolites through membranes. Substrate entry and release,
binding of substrates and cofactors as well as the intrinsic dynamics in these
systems are central to function. We currently develop and apply innovative
solid-state NMR methods to probe protein dynamics in order to relate intrinsic
flexibility to function. We want to reinforce our team with an enthusiastic
postdoctoral researcher with a strong interest in NMR spectroscopy (and the
development thereof) and fundamental aspects of protein function.
The successful candidate will be working on a large enzymatic assembly, using
solid-state NMR methods, complemented by solution-state NMR, as well as on
development of solid-state NMR techniques to address protein dynamics.

Ideally, the successful candidate should have a PhD in chemistry, biochemistry,
biology or physics and experience in solid- or solution-state biomolecular NMR
spectroscopy. Experience in protein expression and purification is useful.

The laboratory hosts a 600MHz solid-state NMR spectrometer equipped with 3.2mm
and 1.6mm MAS probes as well as 600MHz and 800MHz spectrometers equipped with
cryogenic probes for solution-state NMR. It has access to the nearby 1 GHz NMR
spectrometer of the European high field NMR centre in Lyon. Applicants will
also have access to a fully equipped wetlab for preparation of isotopically
labeled NMR samples.

Grenoble is a pleasant city situated in the heart of the French alps, and has
one of Europe’s most vibrant structural biology communities centered around
the European Synchroton Radiation Facility (ESRF), the Laue Langevin Institute
(ILL), the Structural Biology Institute (IBS) and the EMBL Grenoble.

Applications and informal queries about the research projects and the lab
should be addressed by e-mail to Paul Schanda,
Please include in your application a recent CV, names and e-mail addresses of
potential references and a cover letter describing your research interest and
the motivation why you are interested in working with us.

Paul Schanda, Ph.D.
Biomolecular NMR group
Structural Biology Institute Grenoble
41, rue Jules Horowitz
F-38027 Grenoble

Senior Research Fellow in Solid-State NMR

Senior Research Fellow in Solid-State NMR
Department of Physics

£36,862 - £44,016 pa

Fixed Term Contract for 3 Years

You will work together with the Principal Investigators (PIs), the group's existing experimental officer and technical and secretarial support, to provide an optimum environment for carrying out advanced solid-state NMR research in the Warwick Magnetic Resonance Centre, including pushing forward research projects, both together with the PIs and independently.

As well as fulfilling the duties and responsibilities outlined in the further details, you should develop your own research strands, including taking responsibility for driving such projects forward, designing the research, writing papers and procuring external research funding: this can be independently or together with the PIs.

Informal enquiries: John Hanna; e-mail: and Steven Brown; email;

Please quote job vacancy reference number 71278-071.

The closing date/time for applications is midnight (British time) at the end of Friday 05 August 2011.

You must apply using the procedure described below:

Steven Brown
Department of Physics
University of Warwick
Coventry CV4 7AL

Tel: 00 44 24 76574359
Fax: 00 44 24 76150897

webpage address:
Warwick group webpage:
The UK 850 MHz solid-state NMR facility:

Magnetic Resonance at Warwick: Watch the video:

getting to Millburn House:

Dienstag, 5. Juli 2011

Research/Computer Associate

Research/Computer Associate
Department of Biochemistry
Vacancy Reference No: PH08371 Salary: £27,428-£35,788

Limit of tenure applies*

Applications are invited for a postdoctoral research associate, funded by the Collaborative Computing Project for NMR (CCPN), to develop an interface for small molecule screening as an additional module to our CcpNmr Analysis Software. This module would include a graphical user interface to control the workflow for fragment-based screening using NMR and software components for the efficient analysis and screening of NMR spectra for the identification and characterisation of small molecule ligands.

The successful candidate should have a PhD in an appropriate field, be familiar with either NMR spectroscopy or small molecule screening, and have a good working knowledge of Python programming as well as demonstrated experience in the development of software applications. The applicant must be able to work as part of the existing team, and needs to have the initiative and drive to make sure that their part of the project is completed successfully. The project would be carried out in collaboration with our industrial partners and a willingness to travel and to work with our collaborating partners is also important.

Applications should consist of a completed CHRIS/6 form (which can be downloaded from with a CV and the names and addresses of three referees. This should be returned, quoting the reference number, via e-mail to OR by post to the Personnel Secretary, Department of Biochemistry, Building O, Downing Site, Cambridge CB2 1QW UK.

* Limit of tenure: 1 year.

Closing date: 15 July 2011.

The University values diversity and is committed to equality of opportunity.

The University has a responsibility to ensure that all employees are eligible to live and work in the UK.

Montag, 4. Juli 2011

PhD position, Ecole Normale Superieure, Paris

A three-year PhD fellowship is available in the NMR group at Ecole Normale Superieure in Paris.

The graduate student will participate to a project focused on the exploration of the dynamics of intrinsically disordered proteins with new nuclear spin relaxation methods. A full description is available here:

Interested applicants should send their CV to Fabien Ferrage (
Fabien Ferrage
Associate Scientist @CNRS
NMR laboratory
Department of Chemistry
Ecole normale superieure
24, rue Lhomond
75231 Paris Cedex 05
tel: (33) 1 44 32 32 65
fax: (33) 1 44 32 24 02

Postdoc Saclay

12-month post-doctoral position announcement at Saclay, near Paris, at CEA.

Towards a better understanding of gases encapsulation in cage-molecules by NMR and computational chemistry approaches

Dissolved gases are of great importance in various fields of biology (e.g. oxygen, carbon dioxide), medicine (e.g. hyperpolarized 129Xe for MRI applications) and environmental sciences (e.g. green house gas emission like methane or carbon dioxide). Since 2009, the laboratory is involved in a project that aims at a better understanding of hydrophobic interactions of dissolved gases in water through their encapsulation in synthetic cage-molecules. Only a few empirical rules governing the reversible gas receptor interactions are admitted and very little theoretical works have been reported in the literature. In this context, a 12-month postdoctoral position is available at CEA/IRAMIS in Saclay (France, near Paris) under the supervision of Gaspard HUBER, Patrick BERTHAULT and Jean-Pierre DOGNON.

The post-doctoral fellow will be involved in two joined aspects. First, he/she will have to devise and perform NMR experiments designed to acquire reliable kinetic and thermodynamic data, as well as instructive NMR parameters, for various dissolved gases (e.g. small alkanes and noble gases) and cage-molecules (varying size, shape, electronegativity, steric hindrance within two cage-molecule families : cryptophanes and cucurbiturils). Second, he/she will be involved in a computational chemistry approach, mandatory for the interpretation of NMR results. Both aspects should result in the formulation of new laws on gases complexation and on the proposal of new cage molecules, synthesized by our colleagues chemists involved in the project.

The candidate should have good skills in liquid NMR spectroscopy and chemical physics. An experience in computational chemistry would be greatly appreciated. Knowledge in statistics, useful for the determination of experimental errors, would also be valuable.

The position can start from December 2011. The monthly salary is ca. 2200 € (before tax). Interested candidates should send a CV and two recommendation letters to

Post-doc at the interface between NMR and EM at CEA Saclay

A new postdoctoral position is becoming available at CEA Saclay (45 min by train from the center of Paris) in high-field multidimensional NMR applied to large biological assemblies, to be coupled with an exciting ANR granted project on the mechanisms of DNA gating in bacteriophages. The work is focussed on the molecular bases of the head-to-tail connector assembly and function in bacteriophage SPP1. It is based on functional and structural experiments, and in particular the coupling of liquid-state and solid-state Nuclear Magnetic Resonance, X-ray crystallography, Electron Microscopy and Molecular Modelling. Experience in advanced liquid-state and/or solid-state NMR is essential. Expertise in protein purification and molecular modeling will be useful. Starting date is from September 2011. A one year funding that can be extended to three years on a related project is available. Please submit application and CV to:

Dr Sophie Zinn-Justin
Laboratoire de Biologie Structurale et Radiobiologie
iBiTec-S, CEA Saclay
91190 Gif-sur-Yvette



University of Trento, Italy

Faculty of Engineering

Department of Materials Engineering and Industrial Technologies

NMR Laboratory “Klaus Müller”

The Materials Chemistry group of the Department of Materials Engineering and
Industrial Technologies at the University of Trento, Italy, has a position open
for a NMR specialist.
Accordingly, we launch a call for interest for a permanent position in
Materials Chemistry with an emphasis in areas related to materials
characterization by Solid State NMR.
A leadership role in the Solid State NMR Laboratory “Klaus Müller” of the
Department (equipped with two 400 MHz and one 300 MHz Solid State NMR
spectrometers) and the development of strong externally funded research
programs in the field of advanced materials are expected.

The position can be either at the level of associate or full professor,
depending on the candidate’s CV.
Potentially interested Candidates should send a complete resume, including the
names of at least 2 reference persons, to:

prof. Sandra Dirè
Department of Materials Engineering and Industrial Technologies (DIMTI)
Via Mesiano 77
38123 Trento, Italy

Postdoc Italy

The Materials Chemistry Group of the
Department of Materials Engineering and Industrial Technologies,

is looking for an enthusiastic young researcher with a strong background in
Solid State NMR to join our team as a post-doctoral fellow.

The NMR laboratory “Klaus Mueller” is equipped with two 400 MHz and one 300
MHz Solid State NMR spectrometers and our group is mainly involved in sol-gel
synthesis and characterization of inorganic and hybrid O/I materials.

The candidate is expected to be an independent individual that is able to work
well within a team of interdisciplinary researchers

This is a full time 24 month, non-tenure track academic position.

Potentially interested Candidates should send a brief one-page description of
research interest and plans, a CV and contact information for at least 2
reference persons, to:

prof. Sandra Dirè
Department of Materials Engineering and Industrial Technologies (DIMTI)
Via Mesiano 77
38123 Trento, Italy

Postdoctoral Position in Radiology

Postdoctoral Position in Radiology at the Johns Hopkins School of Medicine

Location: Baltimore, MD

There is a postdoctoral fellowship position available within the Russell H. Morgan Department of Radiology, Johns Hopkins School of Medicine and the F.M. Kirby Research Center for Functional Brain Imaging at the Kennedy Krieger Institute for candidates interested in the synthesis of peptides as MRI contrast agents. The candidate is expected to be an independent individual that is able to work well within a team of interdisciplinary researchers.


The successful candidate should have a Ph.D. in Chemistry, Materials Science, Biology, Biomedical Engineering or closely related fields. Candidates with expertise in peptide synthesis and/or high resolution NMR are preferred. Applicants should submit a brief one-page description of research interest and plans, a CV and contact information for three references to Dr. Michael McMahon (

Michael T. McMahon, Ph.D. Phone: (410)502-8188
Assistant Professor
F.M. Kirby Research Center for Functional Brain Imaging
Kennedy Krieger Institute
707 N. Broadway
Baltimore, MD 21205

The Russell H. Morgan Department of Radiology and Radiological Sciences
Johns Hopkins School of Medicine
CRB II Room 4M 63
1550 Orleans St.
Baltimore, MD 21231

Postdoctoral teaching fellowship in NMR methodology for the study of inorganic materials

A postdoctoral teaching fellowship in NMR methodology is available in the ENSCL (Lille, France). It will start in September 2011. This position may be turned into a permanent position of assistant professor in Lille after a training period.

You will join the team of Glasses and NMR methodology in Lille NMR center. You will contribute to the development of original NMR methods for the study of glasses and catalysts. In particular you will be expected to develop techniques for the observation of low-gamma nuclei. You will have access to all the NMR facilities (five superconducting magnets, ranging from 900 MHz to 100 MHz for proton Larmor frequency). Lille is a pleasant city situated in the heart of Europe (30 min from Brussels, 1 h from Paris, 1h from London by train). The university of Lille combines research groups with strong expertise in NMR and EPR spectroscopy as well as catalysis and material science.

You will teach (i) solid-state NMR to graduate students in chemistry as well as (ii) physics (magnetism, electricity) to first-year undergraduate students in chemistry.

You will have a PhD, or equivalent, in Physics or Chemistry. A working knowledge of French is required.

The closing date for application is Monday 11 July 2011.

Applications and informal queries about the lab and research projects should be directed by email to Lionel Montagne ( ).

Olivier Lafon

University of Lille North of France
F-59652, Villeneuve d'Ascq, Cedex, France

Tel : 33 3 20 43 41 43 Fax : 33 3 20 43 68 14
email :

webpage adress :
Lille group webpage :

Assistant Professor

Fixed Term Contract for 5 years

You will join the team of academic and research officers based in the Warwick Centre for Magnetic Resonance (MR). The centre is housed in a purpose built laboratory in Millburn House and combines Nuclear Magnetic Resonance (NMR) and Electron Paramagnetic Resonance (EPR) facilities with expertise being drawn from both the Departments of Physics and Chemistry.

Candidates with expertise in all areas of Magnetic Resonance Spectroscopy are welcomed, especially those with a track record involving the development and/or exploitation of one or more Magnetic Resonance research technique. You will be expected to establish an internationally-leading research activity in a Magnetic Resonance discipline. You will have access to all of the research facilities housed within the Millburn House Centre for Magnetic Resonance.

You will teach and contribute to research leadership, supervision and administration in the Integrated Magnetic Resonance Centre for Doctoral Training, and promote synergy of this activity with the Department of Physics and partner universities.

You will have a PhD, or equivalent, in Physics or a related subject, and will be an active researcher, with a strong record of publications in refereed international journals.

The closing date/time for applications is midnight (British time) at the end of Monday 04 July 2011.

Interview date: 15 July 2011.

Please quote job vacancy reference number 71212-061.

Steven Brown
Department of Physics
University of Warwick
Coventry CV4 7AL

Tel: 00 44 24 76574359
Fax: 00 44 24 76150897

webpage address:
Warwick group webpage:
The UK 850 MHz solid-state NMR facility:

Magnetic Resonance at Warwick: Watch the video:

getting to Millburn House:

MRI Scientist for TIIL

MRI Scientist for TIIL

Translational Imaging Industrial Laboratory (TIIL; part of Singapore Bioimaging Consortium), is a new initiative from Singapore’s A*Star (Agency for Science Technology and Research), providing global biopharma companies with a high quality and state-of-the-art array of preclinical imaging resources directed at enhancing the efficiency and pace of the drug development process.

The Laboratory is currently seeking to recruit an experienced MRI physicists to join our team. The in vivo imaging laboratory assists in drug discovery programmes and focuses on the validation and development of imaging and spectroscopic methods for a number of disease areas, including cardiovascular diseases, oncology, and metabolic disorders.

As part of TIIL, this role will support the development and implementation of MRI methods in order to understand mechanism(s) of drug action, drug efficacy, and safety, and long-term outcomes. These methods may then be incorporated as part of the drug discovery program, ranging from target identification to therapeutic application.

We are looking for a highly motivated individual, who can work independently in a fast-paced environment. This person will collaborate in multidisciplinary teams across disease areas and will keep meticulous records. Responsibilities for this position include performing in vivo MR experiments, analyzing and integrating related data, summarizing results for reporting and publication, and daily operations of the laboratory.

Qualifications and Expertise:

The desired candidate will:

• have an MSc or PhD or equivalent in Medical Physics, Biomedical Engineering, Biomedical Sciences or related fields, with at least 3 years of industrial experience

• have an advanced knowledge of the area of MRI physics and applications

• have a working knowledge of C/C++

• have experience with MR imaging and spectroscopy

• have experience and expertise in pulse sequence programming and applications development

• have digital image/spectroscopy processing or graphical/visual programming skills (Matlab, Analyze, IDL)

• have experience in performing small animal MRI experiments - Animal skills, such as handling, restraining, anaesthesia and injections (IP, IM, IV) in rodents and rabbits
• have familiarity with FDA and QSR regulations

• have the ability to communicate and collaborate with members of a multidisciplinary team

• have the ability to follow directions and perform tasks with continuous attention to detail and safety

• have good communication skills to be effective in a global organization

• must be able to provide at least three references to support qualifications

Research Fellowship in NMR Technology/DNP NMR

*Research Fellowship in NMR Technology/DNP NMR *

Applications are invited for a post based in the Sir Peter Mansfield Magnetic Resonance Centre which is part of the School of Physics and Astronomy at the University of Nottingham. The successful candidate will lead an ambitious hardware development project that focuses on the the design and implementation of a novel spectrometer for Dynamic Nuclear Polarisation enhanced NMR spectroscopy. The project involves extensive industrial collaboration and is funded by the Novel Technology Initiative in Cross-disciplinary Sciences of the EPSRC.

Candidates should have a PhD in physics or a related discipline and preferably have experience in one or several of the following fields: Microwave technology, Cryotechnology, Magnetic Resonance hardware technology, Laser Optics. The successful candidate will join a interdisciplinary group of physicists, chemists and engineers.

Salary will be £27,319 - £31,671 per annum, depending on skills and experience. This post will be offered on a fixed-term contract for a period of three year.

Informal enquiries should be addressed to Dr Walter Köckenberger, Email:

For more details and/or to apply on-line please access: _ _If you are unable to apply on-line please contact the Human Resources Department, tel: ++44 115 951 3262. *Please quote ref. SCI/*SCI992*. Closing date: 8^th July 2011.*

Walter Köckenberger
Sir Peter Mansfield Magnetic Resonance Centre
School of Physics & Astronomy
University of Nottingham
Nottingham NG7 2RD
United Kingdom

p: (44) 115 9515161
f: (44) 115 9515166

NMR Specialist Genomic Biology

The Institute for Genomic Biology has a position open for a NMR Specialist.

Position Announcement

NMR Specialist

Institute for Genomic Biology
University of Illinois Urbana Champaign

The Core Facilities in the Institute for Genomic Biology has purchased a
600 MHz NMR and a Protasis capillary flow probe for natural product
isolation. The new NMR Specialist will primarily be responsible for
developing training materials and maintenance schedules, training NMR
users, and maintaining the NMR. Secondary responsibilities will include
working with users of the optical microscopy instruments.

Currently the core facility at the institute for Genomic Biology houses
$2.5 million of optical microscopy, cleanroom and bioanalytical
equipment and is staffed by three full time academic professionals and
an administrative assistant.

Key Responsibilities
Provide quality training to NMR users.
Develop NMR training materials.
Maintain the NMR including scheduled Cryogen fills.
Work with NMR users to maximize efficient use of the NMR
Aid with training microscopy users as time permits.

Minimum Qualifications Masters Degree in Chemistry or related field. NMR

Desired Qualifications
Experience with proton NMR.
Experience with NMR hardware and software.

This is a full time 12 month, non-tenure track Academic Professional
position with full university benefits. The successful candidate would
start in the early fall. Salary will be commensurate with training and
experience. Please create your candidate profile at and upload your letter of interest (including
email address), resume and contact information for three professional
letters of reference by June 22, 2011. Position available as soon as
possible after the close date. Applicants may be interviewed before the
closing date; however, no hiring decision will be made until after that
date. All requested information must be submitted for your application
to be considered. For further information regarding the application
procedures, you may contact Kim Johnson,
Illinois is an Affirmative Action/Equal Opportunity Employer and
welcomes individuals with diverse backgrounds, experiences, and ideas
who embrace and value diversity and inclusivity.

Post-doc position in spin physics at ETH Zurich

The Spin Physics and Imaging group (Degen Lab at ETH Zurich) is looking for an enthusiastic spin physicist with a strong background in magnetic resonance to join our team as a post-doctoral associate. Our lab is working on combining single nitrogen vacancy spins in diamond (NV centers) with scanning probe microscopy, for application in nanoscale magnetic sensing, imaging, and single spin readout.

Experience that will be valued includes:
- Quantum simulations of spin systems
- Design and application of complex EPR and NMR pulse sequences
- Hands-on experience with microwave and radio-frequency circuitry (we use frequencies up to 20 GHz)
- Experimental or theoretical experience with manipulation and readout of single spin systems, such as optics experiments on quantum dots.

For inquiries and applications please contact Christian Degen at, or visit our website at Please include in your application a recent CV and a short motivation why you are interested in working with us.

The post-doctoral position is funded through the Swiss national competence center in Quantum science and technology (, a platform that offers great opportunities for networking with a number of excellent groups in the field of quantum science.

Prof. Christian Degen
Department of Physics, HPF F6
ETH Zurich
Schafmattstrasse 16
8093 Zurich

Phone: +41 44 633 2336

Mittwoch, 1. Juni 2011

PhD position, Australia

The MacDiarmid Institute for Advanced Materials and Nanotechnology at
the Victoria University of Wellington (Wellington / New Zealand) is
offering a PhD position, available from July 2011.

The research will be in the field of soft matter (complex fluids
investigated by means of Rheo‐NMR under high shear rates, application
of multidimensional NMR methods) with the focus on spatio‐temporal
fluctuations in banded‐flow, wall slip effects and start up flow of
micellar, polymeric and colloidal particles based on fast 3D NMR
velocimetry. The research to be undertaken concerns addressing
fundamental questions related to soft matter as well as the
development of the necessary NMR methodology (including hardware).

The successful applicant will be given the opportunity to work with
Dr. Petrik Galvosas and Professor Paul Callaghan in a well recognised
NMR group ( with strong national and
international collaborations.

The PhD position is fully funded (including fees) and will enable the
successful applicants to stay in a well established academic
( as well as urban
environment ( The scholarship provides a
non‐taxed living allowance of NZ$25,000 per annum, which is a very
comfortable living salary in Wellington, plus the PhD tuition fee for
three years.

Please refer to the Soft Matter and RheoNMR link at for further

Dr. Petrik Galvosas
School of Chemical and Physical Sciences
Victoria University of Wellington
PO Box 600
Wellington 6140, New Zealand
Tel: +64-4-463 6062 (office)
+64-4-463 5911 (lab)
Fax: +64-4-463 5237

PhD or postdoctoral fellowships, Tuebingen,

Max Planck Institute for Developmental Biology
Tuebingen, Germany.

PhD or postdoctoral positions funded by tax free fellowships are available in the research group of Remco Sprangers and in the research group of Silke Wiesner. We are looking for candidates that have a strong interest structural biology and biochemistry. More details about the projects that combine NMR spectroscopy, X-ray crystallography and biochemical approaches can be found below. Both laboratories are very well equipped, including new 600 and 800 MHz NMR spectrometers, crystallization robots and state-of-the-art instrumentation for protein expression and purification. In addition, we have regular access to the synchrotron facility at the SLS.

Applicants for the PhD positions should have a strong background in biochemistry, chemistry and/or biophysics. Applicants for the postdoctoral positions should have a PhD in NMR spectroscopy or X-ray crystallography. Please contact or by June 15, 2011 and include a pdf file with a brief CV, names of two referees and a summary of research interests and previous research projects.

The research group of Remco Sprangers ( studies how protein motions determine enzymatic function. We are especially interested in the machinery that degrades mRNA. Structural changes in the degradation complex allow for a tight regulation of the mRNA decay process that is crucial for cellular homeostasis. To understand how this is achieved on an atomic level, we use novel techniques in high resolution NMR spectroscopy (methyl TROSY) in combination with X-ray crystallography and biochemical experiments.

The research group of Silke Wiesner ( is interested in the structure, function, and regulation of the ubiquitination machinery. Ubiquitination marks proteins for degradation and thereby controls cellular signaling and behavior. We seek to provide a molecular basis for protein ubiquitination and to understand how diseases like cancer arise from dysfunctional ubiquitination enzymes. We gain structural information from NMR and/or X-ray crystallography and combine this information with investigations targeted at functional aspects using both in vitro and in vivo studies.

Leiterin / Leiter der NMR-Abteilung Regensburg

An der Universität Regensburg ist in der Abteilung Zentrale Analytik der Fakultät für Chemie und Pharmazie zum nächstmöglichen Zeitpunkt die Stelle einer
Akademischen Rätin/ eines Akademischen Rates
als Leiterin / Leiter der NMR-Abteilung
im Beamtenverhältnis auf Probe / Lebenszeit zu besetzen.
Die Stelle ist nach Besoldungsgruppe A13 /A 14 bewertet.Zu den Aufgaben gehört die wissenschaftliche, organisatorische und technische Leitung und Weiterentwicklung der NMR-Abteilung, die Beratung in NMR-spektroskopischen Fragen und die Mitwirkung in Ausbildung und Lehre. Erwünscht ist auch die Durchführung von Forschungsprojekten.Voraussetzung ist ein abgeschlossenes Universitätsstudium (bevorzugt Chemie) und eine Promotion auf einem aktuellen Gebiet der NMR-Spektroskopie. Erfahrung mit Strukturrechnungen möglichst inklusive residualer dipolarer Kopplungen ist erwünscht.Neben den allgemeinen beamtenrechtlichen Voraussetzungen ist für die Übernahme in ein Beamtenverhältnis eine mindestens zweijährige wissenschaftliche oder praktische hauptberufliche Tätigkeit nach dem Erwerb der Promotion auf diesem Gebiet erforderlich. Die Universität strebt eine Erhöhung des Frauenanteils an und fordert daher qualifizierte Frauen ausdrücklich zur Bewerbung auf.Schwerbehinderte werden bei im Wesentlichen gleicher Eignung bevorzugt berücksichtigt.
Wir freuen uns auf Ihre ausführliche Bewerbung, die Sie bitte bis zum 20.06.2011 an folgende Adresse senden:
Universität Regensburg
Institut für Organische Chemie
Zentrale Analytik / NMR-Abteilung
Prof. Dr. Ruth M. Gschwind
Universitätsstr. 31
93053 Regensburg

Freitag, 8. April 2011

PhD position France

A PhD position is available at Rennes, France (collaboration between INRA-APBV (Yield under abiotic stress) and Cemagref (IRM-Food)). The project concerns in particular the update of the cellular and metabolic events which contribute to the reallocation of nitrogenous and carbon from senescing leaf tissues in order to define the mains determinants and to improve their efficiency. The ambition based on the two laboratories collaboration is to associate a fine analysis at the cellular level of the structural organization of leaf tissues by an original approach of NMR relaxometry with the concomitant description of the metabolic orientation of products stemming from organels and macromolecules degradation by metabolomic approaches. We will be also testing the validity of the NMR analysis as an efficient integrative tool to characterize senescing tissues and as an effective means of diagnostic and medium throughput phenotyping tool of stress conditions.

The project is highly interdisciplinary and will combine NMR for identification of water in different cell parts with cell biology techniques (non aqueous sub-cellular fractionnation, sub-cellular metabolic profiling, TEM, leaf senescence characterisation (molecular pysiological and biochemical markers).

Applications close - 15 Juin 2011.

Interested applicants should contact Dr Maja Musse ( or Dr Laurent Leport ( directly by submitting their CV.

Maja Musse, PhD
NMR/MRI group
Food process engineering research unit Cemagref
17, avenue de Cucillé
CS 64427
35044 Rennes cédex
tél : 02 23 48 21 79
fax : 02 23 48 21 15

Donnerstag, 7. April 2011

PhD Scholarship in Sydney

Nanoscale Organisation and Dynamics Group
College of Health and Science, University of Western Sydney, Australia
Nanoscale Postgraduate Research Award

Nanoscale PhD Scholarship in Advanced Clinical MRI

The Nanoscale Organisation and Dynamics Group at the University of Western Sydney is seeking two doctoral students to commence a project involved in the development of Advanced MRI Techniques for Clinical Imaging in 2011.

About the Project
The successful applicants will undertake a project in the field of developing next generation diffusion MRI techniques for clinical imaging and are expected to have a research background and some experience in more than one of the following areas:

· Magnetic resonance theory and application
· Operation of Bruker NMR spectrometers
· Mathematical modelling
· Computer visualisation
· Imaging visualisation software such as Amiraâ
· Computational software such as Mapleâ Matlabâor Mathematicaâ

Academic Criteria
Applicants should hold an excellent Bachelor Hons degree in a relevant field, or equivalent qualifications and/or experience.

What does the scholarship provide?

· Tax free stipend of $30,000 per annum and a funded place in the doctoral degree. International candidates may be charged fees
· Funding is also available for project costs and conference travel

Need more information?

· Contact Professor William Price to discuss the project:; +61 2 4620 3336
· Contact the Research Training, Policy and Programs Officer to discuss enrolment and scholarships:

Ms Sandra Lawrence:
· Find out more about the research being undertaken in the Nanoscale Organisation and Dynamics Group at

How to apply
Submit an application form, research proposal and CV by the closing date. The application form can be downloaded from the web:

Professor William S. Price
Nanoscale Organisation and Dynamics Group
College of Health and Science
Campbelltown Campus - Building 21.G.45
University of Western Sydney
Penrith South DC NSW 1797
Phone: [61 2] 4620 3336
FAX: [61 2] 4620 3025
Mobile: 0404 830 398

PhD (6) - Postdoc (5)

Large investment in UltraSense NMR for Analyses, screening and diagnostics.

UltraSense NMR is a large research and development programme, granted by EFRO(EU) and GO, in cooperation between science and business. The project will be run by a consortium between Radboud University Nijmegen: Institute of Molecules and Materials, UMC St. Radboud, University of Twente and 3 knowledge companies: Future Chemistry, Spinnovation Analytical and NovioGendix. Goal of the project is to develop hyperpolarisation equipment and strategies based on both physical (DNP) and chemical (pH2) principles. With the ultrasensitive microfluidic and continuous flow technology and equipment, we will be developing new diagnostic services and a molecular diagnostic test for prostate cancer. For this research programme we are looking for multidisciplined researchers, familiar with the field of physics, chemistry, biophysics, metabolic profiling, molecular diagnostics, who will be working closely together to generate a multidisciplinary research and development team responsible for generating the technology as well as the described prototype products. For the abovementioned developments we are looking for enthusiastic PhD students and postdoctoral researchers who like to be part of a multidisciplinary team in an internationally oriented environment:

1. PhD 1 with a background in synthetic (bio)organic chemistry, continuous flow chemistry, tagging of biomolecules, and with a strong affinity and knowledge of NMR.

2. PhD 2 with NMR/MR experience, preferably experience with working with PHIP. and a strong affinity and knowledge of synthetic organic chemistry.

3. PhD 3 with a master degree in (bio-)chemistry, biophysical chemistry or comparable fields. Experience with NMR and development of new metabolic assays in body fluids, cells and tissue will be appreciated.

4. PhD 4 with a background in Microfluidics and chip technology, lab on a chip, this position will be located at University of Twente

5. PhD 5 with a background in Biomarker tracing and analysis with preferably experience in molecular diagnostics, cancer research, this position will be located at UMC St. Radboud

6. PhD 6 with experience in magnetic resonance. Knowledge of DNP and/or metabolic profiling is a benefit.

7. Postdoc 1 (2 yrs) with a background in organic synthetic chemistry and a strong affinity and knowledge of flow chemistry and NMR techniques.

8. Postdoc 2 (2 yrs) with a strong background in magnetic resonance with an emphasis on methodological development.

9. Technical Researcher/Postdoc (4 yrs) with outstanding technical skills focusing on the development of a novel DNP spectrometer and hyphenated probe in a microfluidic context.

10. Postdoc 4 (2 yrs) with a background in NMR/MR, or pH2 based technology, preferably expertise in methodological development, instrumentation and pH2 hardware development.

11. Postdoc 5 (2 yrs) with NMR/MR experience in the field of biomolecules or biomarker research/ analysis and preferably experience with working with hyperpolarisation or PHIP.

When interested in these vacancies, please send an e-mail to:

Please accompany your e-mail with a cv and refer to the vacancy you’re interested in!

Marian de With
Radboud University
Institute for Molecules and Materials
Physical Chemistry
Tel. +31 24 3652678
Fax +31 24 3652112

Visiting address:
Heyendaalseweg 135
6525 AJ Nijmegen
Postal address:
Postbus 9010
6500 GL Nijmegen


A PhD position is available at Cemagref, Rennes (IRM-Food). This collaborative project amongst the groups IRM-Food and PV-BIA, INRA (Marc Lahaye) aimed at characterisation of microstructure distribution of apple fruit by quantitative MRI.

All the necessary details regarding this position are detailed below. Applications close 15 Juin 2011.

Interested applicants should send the required application document at:

The quantitative MRI and NMR relaxometry offer the possibility to access macroscopic (tissue distribution), mesoscopic (local porosity) and microscopic (subcellular water distribution) changes and associated with chemical and mechanical characterisation of tissues, would make it possible to understand the influence of tissue structure to mechanical properties of the fruit. The main questions that the thesis will try to answer are:

- Among the hystological (cell dimensions), biophysical (turgor pressure, membrane permeability) and chemical characteristics, what are those who determine the relaxation times and diffusion coefficient?

- What is the influence of the porosity and its distribution within the tissues on the mechanical properties of the fruit?

- Do the distributions of the relaxation times and diffusion coefficient measured by MRI and their time variation depend on the plant variety?

- Is it possible to consider the relaxation times, diffusion coefficient and the porosity measured by MRI for the phenotyping?

Relaxation times and apparent diffusion coeficient measured by MRI and NMR will be correlated with macrovision and microscopic images of apple parenchyma and with its chimical and mechanical properties. Fruits with known and very different chaarcteristcs (cell dimensions, firmness, elasticity of apple flesh) will be used.

Scills required by the candidate:
The candidate should have bases on MRI/NMR physics, some knowelage of biology and be able to work in an interdisciplinary environment. A Master's degree or equivalent is required.

Maja Musse, PhD
NMR/MRI group
Food process engineering research unit Cemagref
17, avenue de Cucillé
CS 64427
35044 Rennes cédex
tél : 02 23 48 21 79
fax : 02 23 48 21 15

Mittwoch, 23. März 2011

Doktoranden-Stelle (m/w)

Doktoranden-Stelle (m/w)

Am Max-Planck-Institut für Festkörperforschung (Stuttgart) ist eine Doktoranden-Stelle (m/w) für Projekte im Bereich der Charakterisierung neuartiger Elektrolyte zu besetzen. Voraussetzungen sind ein abgeschlossenes Studium der Chemie oder Physik, experimentelles Geschick und die Fähigkeit, sich in eine interdisziplinär arbeitende Gruppe einzufügen. Erfahrungen im Bereichen der NMR-Spektroskopie wären vorteilhaft.
Die geplanten Arbeiten sind zum einen grundlagenorientiert, zum anderen eingebunden in Projekte zur Entwicklung neuer Materialien für Brennstoffzellen und Batterien (insbesondere Membranen), die zusammen mit anderen Instituten, Universitäten und Unternehmen durchgeführt werden.
Siehe auch:

Ihre Bewerbung mit den üblichen Unterlagen schicken Sie bitte an:

Max-Planck-Institut für Festkörperforschung
K. D. Kreuer
Heisenbergstr. 1
70569 Stuttgart

Postdoc Diffusion NMR

A position for a Project Scientist is available in the Knowledge Centre for Materials Chemistry (KCMC, at the University of Manchester. The role is focused on the development and delivery of a capability to use diffusion NMR to investigate the dynamic behaviour of colloids and nanomaterials in aqueous dispersions. This work would be done in collaboration with external sponsors including industry, charities and research councils.

Candidates should hold a PhD in chemistry or materials science, and a strong research track record in NMR spectroscopy and specifically in diffusion NMR, the related data analysis, and the use of these techniques to investigate the association and behaviour of molecular assemblies in liquid media. Experience in colloid and surface science is also required. Experience of working with industry is desirable

The successful candidate will be working as part of a large research team and will be expected to communicate results at project meetings, in written reports and to industrial sponsors. Short-term projects will be based on a number of clearly defined goals that must be delivered in a timely manner. We therefore seek highly motivated candidates with excellent communication and interpersonal skills, with the ability to interact with persons at all levels within the academic and business communities, and who would enjoy working in a challenging environment and interacting with industry. The position will be particularly suited to candidates who are interested in both fundamental AND applied aspects of science.

The closing date is 18th April 2011; further details may be found at For informal enquiries please contact Professor N Tirelli (

PhD student or Postdoctoral fellow

Seeking a PhD student or Postdoctoral fellow with NMR experience and interest in Microbial Glycobiology

A PhD or postdoctoral position is available immediately at the University of Alberta. The successful candidate will be jointly supervised by Dr. Roderick Wasylishen (Department of Chemistry and Canada Research Chair in Physical Chemistry, and Dr. Christine Szymanski (Department of Biological Sciences and Alberta Ingenuity Centre for Carbohydrate Science,

The student will be involved in a multidisciplinary project examining bacterial capsular polysaccharides and developing new techniques to examine bacterial-host interactions using high-resolution magic-angle spinning NMR. The NMR Facilities in the Department of Chemistry are well equipped for the collaborative research project. Specifically we have access to a Varian 600 with a nanoprobe for magic-angle spinning experiments. Details of the other NMR spectrometers in the Department can be found at: and

Applicants should have a strong background in NMR and biological chemistry. Knowledge of solid-state NMR, molecular modeling and NMR programming would be an asset.

Interested applicants should send a single PDF document containing a CV, one-page statement of research interests and contact information of three references to:

Montag, 14. März 2011

predoctoral fellowship

Dear colleagues,

A predoctoral fellowship is available for 6 months (extended up to 12 months) to perform theoretical and experimental studies of small molecules of pharmaceutical interest based on solid-state NMR spectroscopy. The successful applicant will also have the possibility to pursue with a doctoral programme.
All the necessary details regarding this position are detailed below (contact details and deadlines at the bottom of the message at the end).

Interested applicants should send the required application document (check below) to Dr. José Gomes ( or directly to me.


postdoctoral position King's College

A postdoctoral position supported by the King's College London British Heart Foundation Centre of Excellence is available at King's College London in the field of ROS biology. The project is a collaborative effort amongst the groups of Prof Ajay Shah MD (Cardiovascular Division, King's College London), Dr Conte and Dr Steiner (Randall Division of Cell and Molecular Biophysics, King's College London) aimed at elucidating the molecular mechanism of controlled ROS production in higher organisms.

The project is highly interdisciplinary and will combine structural biology (X-ray and NMR) with biophysical (ITC), biochemical and cell biology work. The post requires experience in molecular biology/protein biochemistry. Proven prior experience in protein expression using the baculovirus system is also considered very important. Additional experience with biophysical methods complementary to structural biology and/or oxygen biochemistry is welcomed.

The post is available immediately and funding is initially for 18 months. Salary will be commensurate to prior experience and qualifications. Interested applicants should contact Dr Maria R Conte ( directly by submitting their CV together with the names of three referees. Informal inquiries are welcome.

Deadline for this application is 21st March 2011.

Maria R Conte
Reader in Structural Biology
Randall Division of Cell and Molecular Biophysics
King’s College London
New Hunt’s House
Guy’s Campus
London SE1 1UL, United Kingdom

Tel +44 (0)20 7848 6194
Fax +44 (0)20 7848 6435

Position of NMR manager in Lille, France

The laboratory of Structural and Functional Glycobiology (UGSF - CNRS UMR 8576) at the University of Lille, France, is looking for a research engineer to manage the liquid state part of the NMR Platform at the University. Composed of several Bruker spectrometers, including a 900MHz Avance III instrument with cryogenic probehead and a SampleJet, a 800MHz Avance III spectrometer for solid state and HRMAS NMR, the platform has the specificity within the national network of high-field NMR ( of combining expertise in liquid and solid state NMR.

The applications of high resolution biomolecular NMR at the UGSF cover most types of biomolecules, with a particular accent on oligosaccharides and proteins, and their interactions. Research at the UGSF aims to develop novel methods (pulse sequences, reduction of sample size, use of sample changer, HRMAS) and novel instrumentation to improve the quality of the measurements, and extract maximal information for the biological systems of interest.

The ideal candidate will be in charge of the maintenance of the different spectrometers, relations with the constructor, planning of the experiments, and set-up of the experiments for novel and experienced users. He/she will play an important role in choosing and implementing existing and novel NMR experiences, and will be particularly involved with the set-up of automatic screening protocols of molecular interactions.

A PhD in high resolution biomolecular NMR and a first professional experience in a NMR laboratory are important criteria for the selection. Further information about the position can be obtained from Guy Lippens, the principal investigator of the 900MHz project (, tel (00 33) 3 20 33 72 41). For administrative information, candidates should contact Mme Martine Ratajczak ( 03 20 33 72 40) before March 28th 2011.

Postdoctoral Fellow

Applications are invited for a Postdoctoral Fellow / Research Associate position at the Center for Biomedical Imaging of the EPFL in Lausanne, Switzerland, in the area of Hyperpolarized Magnetic Resonance Imaging and Spectroscopy.

Hyperpolarized Magnetic Resonance (MR) is a revolutionary and promising technique with a proven potential in biomedicine. Based on Dynamic Nuclear Polarization (DNP), a low-temperature technique used to increase the nuclear spin order, hyperpolarization leads to an improvement in signal-to-noise ratio on the order of 10’000 times. It allows for the detection of tiny amounts of biological substances in vivo and to follow the metabolic pathways of chosen molecules.

Unique hyperpolarizers have been developed within the Swiss DNP Initiative regrouping several departments of the EPFL and the Paul Scherrer Institute. The Center for Biomedical Imaging (CIBM) provides access to two high-field animal MRI systems, one working at 9.4T and the other at 14.1T. One 5T hyperpolarizer is coupled to the 9.4T scanner and another is about to be installed and coupled to the 14.1T scanner.

The selected candidate will be involved in the development of new technologies and protocols to perform in vivo cardiac and brain DNP-enhanced experiments. Emphasis will be put on the use of novel hyperpolarized substrates for metabolic and molecular imaging. Applications in the field of cardiology and oncology will be tested on rodents.

We are seeking for a candidate with a PhD in Physics, Chemistry, Biomedical engineering or related field. The candidate is expected to have a strong background in MR physics from his or her Ph.D. Experience with Varian sequence programming is desirable but is not required. The selected candidate will be part of a team composed of several PhD students and experienced researchers involved in the physical, chemical, biological and biomedical aspects of hyperpolarized MR.

The position is open immediately and for up to 4 years. For consideration, please submit your application including a cover letter, a full CV, and the names and email addresses of three references to

Arnaud Comment
Laboratory for functional and metabolic imaging (LIFMET)

mailing address:

EPFL, Station 6
CH-1015 Lausanne

Phone +41 21 693 7982
Fax +41 21 693 7960

post-doctoral research position

A full time post-doctoral research position is available for a period of one year at the Università del Piemonte Orientale “Amedeo Avogadro”, Alessandria (Italy), on "NMR relaxometric characterization of Gd-based systems for the development of dual imaging probes".

Our lab is part of the European COST Action D38, ”Metal-based Systems for Molecular Imaging Application” and our research activities are aimed at developing efficient Imaging Probes based on Gd(III) complexes. Within the frame of a Regional Project on Innovative Platform for Medical Imaging and in collaboration with academic and industrial partners (University of Turin, Bracco Imaging, Advanced Accelerator Applications, Fluody), we are committed at the synthesis and characterization of innovative dual PET-MRI, SPECT-MRI and MRI-optical probes for the synergistic exploitation of the peculiar properties of the two diagnostic techniques. After complete physico-chemical characterization, these Imaging probes will be tested in vitro and in vivo with Magnetic Resonance Imaging on tumors and other cardiovascular or neurological pathologies.

Candidates are expected to have a PhD degree in Chemistry with a background in coordination chemistry and proven experience in NMR spectroscopy.

NMR facilities include high resolution JEOL ECP-400 and a Bruker Avance III 500 NMR, all equipped with a direct Z-gradient multinuclear probe; Solid-state Bruker Avance III 500 spectrometer with a wide bore 11.7 T magnet; JEOL FA-200 X-band EPR spectrometer; low resolution Stelar NMR spectrometer operating at 20-80 MHz and a Fast Field Cycling Stelar SmartTracer spectrometer operating over a 0.01-10 MHz frequencies range equipped with a variable temperature unit control.

Start date: June-July 2011
Interested candidates should send their biographical sketch and a cover letter summarising research experience and interests to:
Mauro Botta (


Prof. Mauro Botta
Dipartimento di Scienze dell 'Ambiente e della Vita
Università del Piemonte Orientale "A. Avogadro"
Viale Teresa Michel 11, 15121 Alessandria (Italy)
Tel: 0131-360253
Fax: 0131-360250

Montag, 7. März 2011

PhD student project/position

PhD student project/position

A PhD student project/position is available in the area of NMR applied to asymmetric homogeneous catalysis. The project will be jointly supervised in the NMR Department (Dr. Christophe Farès) and in the Department of Homogeneous Catalysis (Prof. Benjamin List) of the MPI for Coal Research in Mülheim an der Ruhr (

The specific goals are to address fundamental questions related to the mechanism of the high stereoselectivity in novel organocatalysts developed at this institute and to discover and develop new strategies towards the characterization of catalytic intermediate and transition states based on advanced NMR methods.

The PhD student will work in collaboration with synthetic chemists in order to optimize compounds which will stabilize intermediate states. She/He will also have full access to a modern NMR laboratory, equipped with seven spectrometers, including a 600-MHz instrument with a cryogenically cooled-probehead.

The position is for a period of three years. We are looking for a talented and motivated individual with a good background in NMR, that wish to invest time and energy to satisfy their curiosity in understanding the fundamental mechanisms behind organocatalysis. A genuine interest in interdisciplinary science will be essential. Education in a relevant discipline such as organic chemistry will be an advantage.

Applications must contain

1. a complete CV with details on education, previous research activities and a list of publications (if any)
2. contact details of at least two personal references

The complete application should be sent to:
Dr Christophe Farès, Department of NMR, 45470 Mülheim an der Ruhr, Germany or
The application must be received no later than March 31, 2011.
For further information regarding this position, please contact Dr Christophe Farès, Department of NMR, 45470 Mülheim an der Ruhr, Germany (Tel: +49 208 306 2130)

Genentech Postdoctoral Fellow

Genentech Postdoctoral Fellow: Structural Biology/NMR Spectroscopy

We have an opportunity for a highly talented Postdoctoral Fellow to join the Protein NMR Group in the Structural Biology Department at Genentech. Our research encompasses the structural analysis of proteins of therapeutic interest, with an emphasis on determining their conformations and ligand-binding properties.

Genentech is now applying our expertise in protein expression, assay development, antibody engineering and drug design to pursue some of the most challenging therapeutic targets in the human proteome, including G protein-coupled receptors and ion channels. The successful candidate will focus their postdoctoral research on the NMR structural analysis of human membrane proteins involved in ion transport and the mechanisms of their functional regulation. The interaction of these proteins with potent and selective antibody fragments, peptides and/or small molecule inhibitors will also be examined. Significant progress on the high-level expression and purification of the proposed membrane structural targets has already been achieved. Moreover, you would be working with a highly collaborative group of scientists whose expertise includes protein NMR spectroscopy, soluble and membrane protein crystallography, ion channel electrophysiology and assay development.

The protein NMR facility includes dedicated 800, 600, and 500 MHz spectrometers, Linux workstations, a fully equipped protein expression and purification lab with expertise in membrane protein production, and access to the Central California 900 MHz spectrometer.

Recent PhD graduate in Biochemistry, Structural Biology or a related discipline, with a strong publication record providing evidence of productive, independent contributions in science. The applicant must have demonstrated expertise in protein expression and purification, and protein NMR spectroscopy . Prior experience working with membrane proteins will be a strong asset, but is not essential. The successful candidate must be motivated, capable of working independently, and enjoy working in a collaborative setting.

Interested candidates should apply at, but feel free to send their CV and cover letter directly to Dr. Melissa Starovasnik ( and Dr. Christopher Koth ( Please visit for additional information.

solid-state NMR engineer position

A one-year solid-state NMR engineer position available

A one-year engineer position is available in the Magnetic Resonance Laboratory (LRM), INAC/SCIB at CEA Grenoble for the technical maintenance of three BRUKER solid-state NMR spectrometers: two AVANCE 400, one of them coupled to a gyrotron, and one DSX 200. The NMR facility is localized at two different sites and will get very soon a complete system to perform solid-state high-resolution NMR coupled to Dynamic Nuclear Polarization (DNP).

Applications fields in high-resolution solid-state NMR at CEA-Grenoble are very broad, ranging from synthetic polymers to biological material, as well as new materials for nanotechnologies. Research at LRM includes methodological developments (pulse sequence design, DNP, NMR/DFT coupling, …) and original instrumentation in order to improve the low intrinsic sensitivity of NMR.

The successful candidate will be in charge of the maintenance and troubleshooting of the spectrometers, contact with suppliers, spectrometer time schedule, supervising external users, and users training. The candidate will be strongly involved in the setup of DNP/NMR experiments, including optimization of sample-preparation protocols for DNP.

The candidate profile includes a PhD thesis in high-resolution solid-state NMR. Previous professional experience in a NMR facility will be particularly considered. Communication and integration skills are highly appreciated.

Further information concerning this position can be obtained from the LRM scientists Sabine Hediger (, tel +33 4 38 78 68 12) and Gaël De Paepe, DNP project leader (, tel +33 4 38 78 58 30).

Motivated candidates should send their CV, two letters of reference, and one letter of motivation before 21st of March 2011 to:

Michel Bardet
17 rue des Martyrs
38054 Grenoble
Cedex 9 - France
tel. 33 4 38 78 57 72 (office)
33 4 38 78 38 33 (secretary)

email :