A full time post-doctoral research position is available for a period of one year at the Università del Piemonte Orientale “Amedeo Avogadro”, Alessandria (Italy), on "NMR relaxometric characterization of Gd-based systems for the development of dual imaging probes".
Our lab is part of the European COST Action D38, ”Metal-based Systems for Molecular Imaging Application” and our research activities are aimed at developing efficient Imaging Probes based on Gd(III) complexes. Within the frame of a Regional Project on Innovative Platform for Medical Imaging and in collaboration with academic and industrial partners (University of Turin, Bracco Imaging, Advanced Accelerator Applications, Fluody), we are committed at the synthesis and characterization of innovative dual PET-MRI, SPECT-MRI and MRI-optical probes for the synergistic exploitation of the peculiar properties of the two diagnostic techniques. After complete physico-chemical characterization, these Imaging probes will be tested in vitro and in vivo with Magnetic Resonance Imaging on tumors and other cardiovascular or neurological pathologies.
Candidates are expected to have a PhD degree in Chemistry with a background in coordination chemistry and proven experience in NMR spectroscopy.
NMR facilities include high resolution JEOL ECP-400 and a Bruker Avance III 500 NMR, all equipped with a direct Z-gradient multinuclear probe; Solid-state Bruker Avance III 500 spectrometer with a wide bore 11.7 T magnet; JEOL FA-200 X-band EPR spectrometer; low resolution Stelar NMR spectrometer operating at 20-80 MHz and a Fast Field Cycling Stelar SmartTracer spectrometer operating over a 0.01-10 MHz frequencies range equipped with a variable temperature unit control.
Start date: June-July 2011
Interested candidates should send their biographical sketch and a cover letter summarising research experience and interests to:
Mauro Botta (firstname.lastname@example.org).
Prof. Mauro Botta
Dipartimento di Scienze dell 'Ambiente e della Vita
Università del Piemonte Orientale "A. Avogadro"
Viale Teresa Michel 11, 15121 Alessandria (Italy)