Mittwoch, 1. Dezember 2010

Postdoctoral Position in NMR and molecular modeling at Paris Descartes University

Paris Descartes University

12 months post-doctoral position in Structural Biology NMR.

The postdoctoral position is available from February 2011 in the Paris Descartes University to characterize the interaction of new anti-cancer inhibitors with phosphorylated peptide-betaTrCP complex.

Applicants should have a Ph.D. in Biochemistry, Chemistry or related fields.

The candidate is expected to have a strong expertise in solution NMR with in-depth training in NMR receptor-ligand interaction, protein structures and dynamics, and drug-protein interactions. Familiarity with biochemistry, biophysics, and molecular biology is desirable.
Experience with molecular modelling (docking, virtual screening) and python language will be a big plus.

The candidate will join our NMR & Molecular modeling team of the laboratory of Chemical and Biochemical Pharmacology and Toxicology (UMR8601 CNRS), and be responsible for the development and structural analysis of anti-cancer by high-resolution solution NMR and molecular modeling. The main approach will be to characterize the interaction by transfer-NMR experiments (STD, WaterLOGSY, ...) and to participate in the development of AuPosSOM software ( to classify molecules according to their contact pattern with the target of interest and 2D/3D QSAR modeling.

Funding for the position is provided by the French National Agency of Research (ANR) for 1 year.

For any queries about the lab and research projects, please contact Nathalie Evrard-Todeschi by e-mail:


Dr Gildas BERTHO
Université Paris Descartes
Équipe de RMN et Modélisation Moléculaire
45 rue des Saints-Pères
75006 Paris, FRANCE
Tel : +33-(0)1-42-86-21-82
Fax : +33-(0)1-42-86-40-50
Email :