Dienstag, 7. August 2012


Postdoctoral positions are available in the research group of Professor Josh Wand in the Department of Biochemistry & Biophysics and the Johnson Research Foundation of the University of Pennsylvania Perelman School of Medicine. Located in Philadelphia, the University of Pennsylvania is a cosmopolitan center of advanced research across the spectrum of the life and physical sciences. Areas of current interest in the Wand laboratory are creative uses of high pressure NMR to explore protein structural cooperativity; NMR spectroscopy of encapsulated proteins dissolved in low viscosity fluids to examine protein hydration and hydration dependent dynamics; uses of reverse micelle encapsulation in structural biology especially membrane-anchored proteins; development and use of advanced NMR relaxation methods to illuminate the character of protein motion and to provide a dynamic proxy for conformational entropy in a variety of functional contexts such as ligand binding, catalysis and evolution; development of NMR data collection strategies and associated software particularly in the realm of sparse sampling; validation of molecular dynamics simulations. Extensive NMR instrumentation is available. See wandlab.org for additional information. Candidates should hold the Ph.D. degree or equivalent and have extensive experience in protein biophysics and/or NMR spectroscopy. Applicants should forward a c.v. and have two letters of reference sent directly to Professor Wand (wand@mail.med.upenn.edu). A. Joshua Wand, Ph.D. Benjamin Rush Professor of Biochemistry & Biophysics Department of Biochemistry & Biophysics University of Pennsylvania Perelman School of Medicine 905 Stellar Chance Laboratories 422 Curie Blvd Philadelphia, PA 19104-6059 telephone 215-573-7288 facsimile 215-573-7290 e-mail wand@mail.med.upenn.edu