Donnerstag, 20. Mai 2010

post-doc position at the Burnham Institute

Principal Investigator: Sepideh Khorasanizadeh
E-Mail: sdickstein@sanfordburnham.org

Duties & Responsibilities: We have an immediate opening for a Postdoctoral Associate to join the Department of Metabolic Signaling and Disease Program at the Sanford-Burnham Medical Research Institute in Orlando, Florida. The primary responsibilities will be to delineate the solution structures of proteins purified to homogeneity and to identify active surfaces for binding and/or catalysis. Applicant is expected to collect, process, analyze and interpret high resolution NMR data on a state-of-the-art 800 MHz Bruker spectrometer. Applicant will also be involved in implementing NMR-based strategies to further support drug or tool compound discovery program. These NMR studies will complement protein analysis by other methods used in our laboratory including MALDI-TOF, surface Plasmon resonance, isothermal titration calorimetry, fluorescence, circular Dichroism, and X-ray crystallography.

Requirements: The successful candidate will have a Ph.D. in chemistry, biochemistry or biophysics. He/She must have already solved solution structures of proteins, having published at least one first-author manuscript describing the atomic structure of a protein. Applicants should forward three letters of reference testifying evidence of productive and independent contributions in science. Please forward C.V., cover letter and 3 letters of reference to Ms. Stephanie Dickstein e-mail address: sdickstein@sanfordburnham.org