Montag, 4. Juli 2011

Research Fellowship in NMR Technology/DNP NMR

*Research Fellowship in NMR Technology/DNP NMR *

Applications are invited for a post based in the Sir Peter Mansfield Magnetic Resonance Centre which is part of the School of Physics and Astronomy at the University of Nottingham. The successful candidate will lead an ambitious hardware development project that focuses on the the design and implementation of a novel spectrometer for Dynamic Nuclear Polarisation enhanced NMR spectroscopy. The project involves extensive industrial collaboration and is funded by the Novel Technology Initiative in Cross-disciplinary Sciences of the EPSRC.

Candidates should have a PhD in physics or a related discipline and preferably have experience in one or several of the following fields: Microwave technology, Cryotechnology, Magnetic Resonance hardware technology, Laser Optics. The successful candidate will join a interdisciplinary group of physicists, chemists and engineers.

Salary will be £27,319 - £31,671 per annum, depending on skills and experience. This post will be offered on a fixed-term contract for a period of three year.

Informal enquiries should be addressed to Dr Walter Köckenberger, Email: walter.kockenberger@nottingham.ac.uk.

For more details and/or to apply on-line please access: _http://www.nottingham.ac.uk/jobs/currentvacancies/ref/SCI992. _If you are unable to apply on-line please contact the Human Resources Department, tel: ++44 115 951 3262. *Please quote ref. SCI/*SCI992*. Closing date: 8^th July 2011.*

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Walter Köckenberger
Sir Peter Mansfield Magnetic Resonance Centre
School of Physics & Astronomy
University of Nottingham
Nottingham NG7 2RD
United Kingdom

p: (44) 115 9515161
f: (44) 115 9515166

NMR Specialist Genomic Biology

The Institute for Genomic Biology has a position open for a NMR Specialist.

http://www.igb.illinois.edu/sites/default/files/upload/NMR%20Specialist%20Ad%205-2011.pdf

Position Announcement

NMR Specialist

Institute for Genomic Biology
University of Illinois Urbana Champaign

The Core Facilities in the Institute for Genomic Biology has purchased a
600 MHz NMR and a Protasis capillary flow probe for natural product
isolation. The new NMR Specialist will primarily be responsible for
developing training materials and maintenance schedules, training NMR
users, and maintaining the NMR. Secondary responsibilities will include
working with users of the optical microscopy instruments.

Currently the core facility at the institute for Genomic Biology houses
$2.5 million of optical microscopy, cleanroom and bioanalytical
equipment and is staffed by three full time academic professionals and
an administrative assistant.

Key Responsibilities
Provide quality training to NMR users.
Develop NMR training materials.
Maintain the NMR including scheduled Cryogen fills.
Work with NMR users to maximize efficient use of the NMR
Aid with training microscopy users as time permits.

Minimum Qualifications Masters Degree in Chemistry or related field. NMR
experience.

Desired Qualifications
Experience with proton NMR.
Experience with NMR hardware and software.

This is a full time 12 month, non-tenure track Academic Professional
position with full university benefits. The successful candidate would
start in the early fall. Salary will be commensurate with training and
experience. Please create your candidate profile at
http://jobs.illinois.edu and upload your letter of interest (including
email address), resume and contact information for three professional
letters of reference by June 22, 2011. Position available as soon as
possible after the close date. Applicants may be interviewed before the
closing date; however, no hiring decision will be made until after that
date. All requested information must be submitted for your application
to be considered. For further information regarding the application
procedures, you may contact Kim Johnson, kljohns@igb.illinois.edu.
Illinois is an Affirmative Action/Equal Opportunity Employer and
welcomes individuals with diverse backgrounds, experiences, and ideas
who embrace and value diversity and inclusivity.
(www.inclusiveillinois.illinois.edu)

Post-doc position in spin physics at ETH Zurich

The Spin Physics and Imaging group (Degen Lab at ETH Zurich) is looking for an enthusiastic spin physicist with a strong background in magnetic resonance to join our team as a post-doctoral associate. Our lab is working on combining single nitrogen vacancy spins in diamond (NV centers) with scanning probe microscopy, for application in nanoscale magnetic sensing, imaging, and single spin readout.

Experience that will be valued includes:
- Quantum simulations of spin systems
- Design and application of complex EPR and NMR pulse sequences
- Hands-on experience with microwave and radio-frequency circuitry (we use frequencies up to 20 GHz)
- Experimental or theoretical experience with manipulation and readout of single spin systems, such as optics experiments on quantum dots.

For inquiries and applications please contact Christian Degen at degenc@ethz.ch, or visit our website at http://www.spin.ethz.ch/. Please include in your application a recent CV and a short motivation why you are interested in working with us.

The post-doctoral position is funded through the Swiss national competence center in Quantum science and technology (http://www.nccr-qsit.ethz.ch/), a platform that offers great opportunities for networking with a number of excellent groups in the field of quantum science.

-------------------------------------
Prof. Christian Degen
Department of Physics, HPF F6
ETH Zurich
Schafmattstrasse 16
8093 Zurich
Switzerland

Phone: +41 44 633 2336
Email: degenc@ethz.ch
Web: http://www.spin.ethz.ch
-------------------------------------

Mittwoch, 1. Juni 2011

PhD position, Australia

The MacDiarmid Institute for Advanced Materials and Nanotechnology at
the Victoria University of Wellington (Wellington / New Zealand) is
offering a PhD position, available from July 2011.

The research will be in the field of soft matter (complex fluids
investigated by means of Rheo‐NMR under high shear rates, application
of multidimensional NMR methods) with the focus on spatio‐temporal
fluctuations in banded‐flow, wall slip effects and start up flow of
micellar, polymeric and colloidal particles based on fast 3D NMR
velocimetry. The research to be undertaken concerns addressing
fundamental questions related to soft matter as well as the
development of the necessary NMR methodology (including hardware).

The successful applicant will be given the opportunity to work with
Dr. Petrik Galvosas and Professor Paul Callaghan in a well recognised
NMR group (http://www.macdiarmid.ac.nz/nmr/) with strong national and
international collaborations.

The PhD position is fully funded (including fees) and will enable the
successful applicants to stay in a well established academic
(http://www.victoria.ac.nz/scps/index.aspx) as well as urban
environment (http://www.wellingtonnz.com/). The scholarship provides a
non‐taxed living allowance of NZ$25,000 per annum, which is a very
comfortable living salary in Wellington, plus the PhD tuition fee for
three years.

Please refer to the Soft Matter and RheoNMR link at
http://www.victoria.ac.nz/scps/study/scholarships.aspx for further
details.

------------------------------------------------------------------------
Dr. Petrik Galvosas
School of Chemical and Physical Sciences
Victoria University of Wellington
PO Box 600
Wellington 6140, New Zealand
Tel: +64-4-463 6062 (office)
+64-4-463 5911 (lab)
Fax: +64-4-463 5237
mailto:Petrik.Galvosas@vuw.ac.nz

PhD or postdoctoral fellowships, Tuebingen,

Max Planck Institute for Developmental Biology
Tuebingen, Germany.

PhD or postdoctoral positions funded by tax free fellowships are available in the research group of Remco Sprangers and in the research group of Silke Wiesner. We are looking for candidates that have a strong interest structural biology and biochemistry. More details about the projects that combine NMR spectroscopy, X-ray crystallography and biochemical approaches can be found below. Both laboratories are very well equipped, including new 600 and 800 MHz NMR spectrometers, crystallization robots and state-of-the-art instrumentation for protein expression and purification. In addition, we have regular access to the synchrotron facility at the SLS.

Applicants for the PhD positions should have a strong background in biochemistry, chemistry and/or biophysics. Applicants for the postdoctoral positions should have a PhD in NMR spectroscopy or X-ray crystallography. Please contact remco.sprangers@tuebingen.mpg.de or silke.wiesner@tuebingen.mpg.de by June 15, 2011 and include a pdf file with a brief CV, names of two referees and a summary of research interests and previous research projects.

The research group of Remco Sprangers (http://www.eb.tuebingen.mpg.de/research-groups/remco-sprangers) studies how protein motions determine enzymatic function. We are especially interested in the machinery that degrades mRNA. Structural changes in the degradation complex allow for a tight regulation of the mRNA decay process that is crucial for cellular homeostasis. To understand how this is achieved on an atomic level, we use novel techniques in high resolution NMR spectroscopy (methyl TROSY) in combination with X-ray crystallography and biochemical experiments.

The research group of Silke Wiesner (http://www.eb.tuebingen.mpg.de/research-groups/silke-wiesner) is interested in the structure, function, and regulation of the ubiquitination machinery. Ubiquitination marks proteins for degradation and thereby controls cellular signaling and behavior. We seek to provide a molecular basis for protein ubiquitination and to understand how diseases like cancer arise from dysfunctional ubiquitination enzymes. We gain structural information from NMR and/or X-ray crystallography and combine this information with investigations targeted at functional aspects using both in vitro and in vivo studies.

Leiterin / Leiter der NMR-Abteilung Regensburg

An der Universität Regensburg ist in der Abteilung Zentrale Analytik der Fakultät für Chemie und Pharmazie zum nächstmöglichen Zeitpunkt die Stelle einer
Akademischen Rätin/ eines Akademischen Rates
als Leiterin / Leiter der NMR-Abteilung
im Beamtenverhältnis auf Probe / Lebenszeit zu besetzen.
Die Stelle ist nach Besoldungsgruppe A13 /A 14 bewertet.Zu den Aufgaben gehört die wissenschaftliche, organisatorische und technische Leitung und Weiterentwicklung der NMR-Abteilung, die Beratung in NMR-spektroskopischen Fragen und die Mitwirkung in Ausbildung und Lehre. Erwünscht ist auch die Durchführung von Forschungsprojekten.Voraussetzung ist ein abgeschlossenes Universitätsstudium (bevorzugt Chemie) und eine Promotion auf einem aktuellen Gebiet der NMR-Spektroskopie. Erfahrung mit Strukturrechnungen möglichst inklusive residualer dipolarer Kopplungen ist erwünscht.Neben den allgemeinen beamtenrechtlichen Voraussetzungen ist für die Übernahme in ein Beamtenverhältnis eine mindestens zweijährige wissenschaftliche oder praktische hauptberufliche Tätigkeit nach dem Erwerb der Promotion auf diesem Gebiet erforderlich. Die Universität strebt eine Erhöhung des Frauenanteils an und fordert daher qualifizierte Frauen ausdrücklich zur Bewerbung auf.Schwerbehinderte werden bei im Wesentlichen gleicher Eignung bevorzugt berücksichtigt.
Wir freuen uns auf Ihre ausführliche Bewerbung, die Sie bitte bis zum 20.06.2011 an folgende Adresse senden:
Universität Regensburg
Institut für Organische Chemie
Zentrale Analytik / NMR-Abteilung
Prof. Dr. Ruth M. Gschwind
Universitätsstr. 31
93053 Regensburg

Freitag, 8. April 2011

PhD position France

A PhD position is available at Rennes, France (collaboration between INRA-APBV (Yield under abiotic stress) and Cemagref (IRM-Food)). The project concerns in particular the update of the cellular and metabolic events which contribute to the reallocation of nitrogenous and carbon from senescing leaf tissues in order to define the mains determinants and to improve their efficiency. The ambition based on the two laboratories collaboration is to associate a fine analysis at the cellular level of the structural organization of leaf tissues by an original approach of NMR relaxometry with the concomitant description of the metabolic orientation of products stemming from organels and macromolecules degradation by metabolomic approaches. We will be also testing the validity of the NMR analysis as an efficient integrative tool to characterize senescing tissues and as an effective means of diagnostic and medium throughput phenotyping tool of stress conditions.

The project is highly interdisciplinary and will combine NMR for identification of water in different cell parts with cell biology techniques (non aqueous sub-cellular fractionnation, sub-cellular metabolic profiling, TEM, leaf senescence characterisation (molecular pysiological and biochemical markers).

Applications close - 15 Juin 2011.

Interested applicants should contact Dr Maja Musse (maja.musse@cemagref.fr) or Dr Laurent Leport (laurent.leport@univ-rennes1.fr) directly by submitting their CV.

Maja Musse, PhD
NMR/MRI group
Food process engineering research unit Cemagref
17, avenue de Cucillé
CS 64427
35044 Rennes cédex
tél : 02 23 48 21 79
fax : 02 23 48 21 15
mailto:maja.musse@cemagref.fr

Donnerstag, 7. April 2011

PhD Scholarship in Sydney

Nanoscale Organisation and Dynamics Group
College of Health and Science, University of Western Sydney, Australia
Nanoscale Postgraduate Research Award

Nanoscale PhD Scholarship in Advanced Clinical MRI

The Nanoscale Organisation and Dynamics Group at the University of Western Sydney is seeking two doctoral students to commence a project involved in the development of Advanced MRI Techniques for Clinical Imaging in 2011.

About the Project
The successful applicants will undertake a project in the field of developing next generation diffusion MRI techniques for clinical imaging and are expected to have a research background and some experience in more than one of the following areas:

· Magnetic resonance theory and application
· Operation of Bruker NMR spectrometers
· Mathematical modelling
· Computer visualisation
· Imaging visualisation software such as Amiraâ
· Computational software such as Mapleâ Matlabâor Mathematicaâ

Academic Criteria
Applicants should hold an excellent Bachelor Hons degree in a relevant field, or equivalent qualifications and/or experience.

What does the scholarship provide?

· Tax free stipend of $30,000 per annum and a funded place in the doctoral degree. International candidates may be charged fees
· Funding is also available for project costs and conference travel

Need more information?

· Contact Professor William Price to discuss the project: w.price@uws.edu.au; +61 2 4620 3336
· Contact the Research Training, Policy and Programs Officer to discuss enrolment and scholarships:

Ms Sandra Lawrence: sg.lawrence@uws.edu.au
· Find out more about the research being undertaken in the Nanoscale Organisation and Dynamics Group at
http://www.uws.edu.au/nanoscale/nanoscale_organisation_and_dynamics

How to apply
Submit an application form, research proposal and CV by the closing date. The application form can be downloaded from the web:

www.uws.edu.au/research/scholarships
APPLICATIONS CLOSE 20 APRIL 2011
_______________________________________________________________

Professor William S. Price
Nanoscale Organisation and Dynamics Group
College of Health and Science
Campbelltown Campus - Building 21.G.45
University of Western Sydney
Penrith South DC NSW 1797
AUSTRALIA
E-mail: w.price@uws.edu.au
Phone: [61 2] 4620 3336
FAX: [61 2] 4620 3025
Mobile: 0404 830 398

http://www.uws.edu.au/nano
http://www.uws.edu.au/nmr
http://www.anif.org.au/

PhD (6) - Postdoc (5)

Large investment in UltraSense NMR for Analyses, screening and diagnostics.

UltraSense NMR is a large research and development programme, granted by EFRO(EU) and GO, in cooperation between science and business. The project will be run by a consortium between Radboud University Nijmegen: Institute of Molecules and Materials, UMC St. Radboud, University of Twente and 3 knowledge companies: Future Chemistry, Spinnovation Analytical and NovioGendix. Goal of the project is to develop hyperpolarisation equipment and strategies based on both physical (DNP) and chemical (pH2) principles. With the ultrasensitive microfluidic and continuous flow technology and equipment, we will be developing new diagnostic services and a molecular diagnostic test for prostate cancer. For this research programme we are looking for multidisciplined researchers, familiar with the field of physics, chemistry, biophysics, metabolic profiling, molecular diagnostics, who will be working closely together to generate a multidisciplinary research and development team responsible for generating the technology as well as the described prototype products. For the abovementioned developments we are looking for enthusiastic PhD students and postdoctoral researchers who like to be part of a multidisciplinary team in an internationally oriented environment:

1. PhD 1 with a background in synthetic (bio)organic chemistry, continuous flow chemistry, tagging of biomolecules, and with a strong affinity and knowledge of NMR.

2. PhD 2 with NMR/MR experience, preferably experience with working with PHIP. and a strong affinity and knowledge of synthetic organic chemistry.

3. PhD 3 with a master degree in (bio-)chemistry, biophysical chemistry or comparable fields. Experience with NMR and development of new metabolic assays in body fluids, cells and tissue will be appreciated.

4. PhD 4 with a background in Microfluidics and chip technology, lab on a chip, this position will be located at University of Twente

5. PhD 5 with a background in Biomarker tracing and analysis with preferably experience in molecular diagnostics, cancer research, this position will be located at UMC St. Radboud

6. PhD 6 with experience in magnetic resonance. Knowledge of DNP and/or metabolic profiling is a benefit.

7. Postdoc 1 (2 yrs) with a background in organic synthetic chemistry and a strong affinity and knowledge of flow chemistry and NMR techniques.

8. Postdoc 2 (2 yrs) with a strong background in magnetic resonance with an emphasis on methodological development.

9. Technical Researcher/Postdoc (4 yrs) with outstanding technical skills focusing on the development of a novel DNP spectrometer and hyphenated probe in a microfluidic context.

10. Postdoc 4 (2 yrs) with a background in NMR/MR, or pH2 based technology, preferably expertise in methodological development, instrumentation and pH2 hardware development.

11. Postdoc 5 (2 yrs) with NMR/MR experience in the field of biomolecules or biomarker research/ analysis and preferably experience with working with hyperpolarisation or PHIP.

When interested in these vacancies, please send an e-mail to: m.dewith@science.ru.nl

Please accompany your e-mail with a cv and refer to the vacancy you’re interested in!
--

--
Marian de With
Radboud University
Institute for Molecules and Materials
Physical Chemistry
Tel. +31 24 3652678
Fax +31 24 3652112
Web: www.ru.nl/physchem

Visiting address:
Heyendaalseweg 135
6525 AJ Nijmegen
Postal address:
Postbus 9010
6500 GL Nijmegen

PhD MRI

A PhD position is available at Cemagref, Rennes (IRM-Food). This collaborative project amongst the groups IRM-Food and PV-BIA, INRA (Marc Lahaye) aimed at characterisation of microstructure distribution of apple fruit by quantitative MRI.

All the necessary details regarding this position are detailed below. Applications close 15 Juin 2011.

Interested applicants should send the required application document at: maja.musse@cemagref.fr.

Purpose:
The quantitative MRI and NMR relaxometry offer the possibility to access macroscopic (tissue distribution), mesoscopic (local porosity) and microscopic (subcellular water distribution) changes and associated with chemical and mechanical characterisation of tissues, would make it possible to understand the influence of tissue structure to mechanical properties of the fruit. The main questions that the thesis will try to answer are:

- Among the hystological (cell dimensions), biophysical (turgor pressure, membrane permeability) and chemical characteristics, what are those who determine the relaxation times and diffusion coefficient?

- What is the influence of the porosity and its distribution within the tissues on the mechanical properties of the fruit?

- Do the distributions of the relaxation times and diffusion coefficient measured by MRI and their time variation depend on the plant variety?

- Is it possible to consider the relaxation times, diffusion coefficient and the porosity measured by MRI for the phenotyping?

Relaxation times and apparent diffusion coeficient measured by MRI and NMR will be correlated with macrovision and microscopic images of apple parenchyma and with its chimical and mechanical properties. Fruits with known and very different chaarcteristcs (cell dimensions, firmness, elasticity of apple flesh) will be used.

Scills required by the candidate:
The candidate should have bases on MRI/NMR physics, some knowelage of biology and be able to work in an interdisciplinary environment. A Master's degree or equivalent is required.

Maja Musse, PhD
NMR/MRI group
Food process engineering research unit Cemagref
17, avenue de Cucillé
CS 64427
35044 Rennes cédex
tél : 02 23 48 21 79
fax : 02 23 48 21 15
mailto:maja.musse@cemagref.fr