Freitag, 15. August 2008

Postdoctoral position in SSNMR studies of mammalian prions

Hospital for Sick Children, Toronto

Postdoctoral position in solid-state NMR studies of mammalian prions

A postdoctoral position in biomolecular solid-state NMR is available at
the Hospital for Sick Children. This position will focus on structural
characterization of oligomeric and fibrillar states of mammalian prion
proteins by solid state NMR. This work is being carried out in
collaboration with other structural and biophysical groups at the
University of Toronto. The Sharpe lab is located within the Molecular
Structure and Function Program at the Hospital for Sick Children and the
Department of Biochemistry at the University of Toronto, providing a
diverse and stimulating research environment. The research group is
fully equipped for cloning, mutagenesis, protein expression and
purification, with access to peptide synthesis, computational biology
facilities and full-time use of a 500 MHz spectrometer for solids MAS
and static experiments. In addition, access to the National Solid-State
900 MHz NMR facility in Ottawa is also available for this project.

Applicants should possess a recent Ph.D. (last 5 years). Experience in
protein NMR (solution or solid state) or a strong background in
amyloid/prion protein structure is a significant asset, although highly
qualified and motivated individuals with related backgrounds are invited
to apply. The start date for this position is negotiable, but is
available immediately. Interested candidates should send a CV and
contact information for 3 references to:

Dr. Simon Sharpe
Molecular Structure and Function
Hospital for Sick Children
555 University Ave,
Toronto, ON
Canada M5G 1X8