MRI staff scientist position in Gainesville, FL

The Advanced Magnetic Resonance Imaging and Spectroscopy (AMRIS) Facility seeks an MR imaging scientist or engineer for the permanent research staff position of Coordinator of Research Programs and Services in the Magnetic Resonance Imaging Program. Minimum qualifications include a Ph.D. in Physical Sciences or Engineering, with a demonstrated expertise in techniques and applications of high field MR imaging. Previous experience in pulse sequence design and implementation is desirable. Experience working with live animals is especially welcome.

The successful candidate will be expected to provide support to scientists at the University of Florida who use the facility as well as the external user program supported by the National High Magnetic Field Laboratory (NHMFL). This position offers unique opportunities to contribute to the development of the MR imaging program at AMRIS and the NHMFL by conducting independent and collaborative research projects. The position will be based in Gainesville, but as there is a close relationship with the NMR Spectroscopy and Imaging Program at the National High Magnetic Field Laboratory in Tallahassee, occasional travel will be expected. Ongoing research in the facility includes development of novel, primarily diffusion-based techniques for magnetic resonance microscopy, the investigation of novel contrast agents at ultra-high magnetic field, and implementation and maintenance of standard imaging protocols, including cardiac imaging and fMRI. Candidates with an interest in in vivo NMR, in the development of novel methods and/or instrumentation are especially encouraged to apply.

As part of its MR imaging capabilities, AMRIS currently houses a 3T 16 channel Phillips whole body system, a 4.7T 30 cm Bruker Scanner, an 11T 40cm Bruker Scanner, and a 17.6T 8.9cm Bruker System. A 21T 10.4cm Bruker system is housed at the NHMFL facility in Tallahassee. At the end of 2009 the 11T magnet will undergo a system upgrade.

Specific job requirements:

Responsible for coordinating, scheduling and ensuring proper utilization of research facilities.
Recommend and implement operating policies and procedures in the AMRIS facility.
Keep abreast of current developments and ensures compliance with relevant laws and regulations.
Plan and participate in research projects.
Direct and modify research plans.
Develop methods and techniques for, and evaluate results of, experiments or studies.
Prepare and review manuscripts for publication and presentations at scientific meetings.
May serve as liaison between the AMRIS facility and outside agencies and the general public.

For additional information on applying, please contact Dr. Joanna R. Long at jrlong@mbi.ufl.edu or Dr. Glenn Walter at glennw@ufl.edu. Applications will be evaluated beginning April 30, 2009. The University of Florida is an Equal Opportunity/Access/Affirmative Action Employer.

Job opening in Lyon

The High Field NMR Center in Lyon seeks a NMR spectroscopist (CNRS position)
to manage the NMR instruments (from 500 to 1000 MHz) and the activities of
its national and European facilities.

Primary responsibilities: to oversee the day to day operation of the NMR
instruments in support of research for in-house and external researchers; to
assist the external users in their research and provide the most appropriate
NMR experiments for their activities in the Center; to actively participate
in the installation of new equipment (magnets, probes, consoles, computers);
and to assist students and postdoctoral researchers in the use of the NMR
instruments.

Required qualifications: Master or Ph.D. in chemistry or other physical
science; experience in NMR spectroscopy. Previous research experience in the
field of NMR, including the development of scientific applications and
experimental techniques.

To apply: please contact Anne Lesage (Anne.Lesage@ens-lyon.fr)

Closing date for application: is July 10, 2009

Dauerstelle wiss. Mitarbeiter/-in Hannover

Am Institut für Organische Chemie ist eine Stelle als
wiss. Mitarbeiter/-in (EntgGr. E14)
zum 01. September 2009 zu besetzen. Die Stelle ist unbefristet.

Ausstattung des Arbeitsplatzes
Leitung und Betreuung der NMR-Einrichtungen: Das NMR-Labor verfügt über ein 200-, zwei 400- und ein 500-MHz-NMR-Spektrometer (mit Cryoprobenkopf; teilweise im Open-Access-Betrieb), alle von der Firma Bruker. Sie werden hauptsächlich bei der Strukturaufklärung kleiner und mittelgroßer Moleküle aus dem Bereich der Wirk- und Naturstoffchemie in Lösung eingesetzt.

Aufgaben
Gesucht wird ein/e promovierte/r Wissenschaftler/in, der/die mit allen aktuellen NMR-Messtechniken, aber auch mit der technischen Betreuung und Wartung der NMR-Geräte gut vertraut ist. Für die Mitarbeit im routinemäßigen Messbetrieb stehen zwei seit Jahren erfahrene Technikerinnen zur Verfuegung, die unter seiner/ihrer Anleitung arbeiten.
Zu den Aufgaben des/r Stelleninhabers/in gehören ausserdem die Teilnahme an Spektroskopie-relevanten Lehrveranstaltungen, Betrieb und Wartung des hausinternen NMR- und Mailservers sowie Beratung und Koordination der kommerziellen Software im Hause.
Der/die Stelleninhaber/in soll zudem die wissenschaftlichen Mitarbeiter aller Arbeitskreise des Instituts bei der Auswahl geeigneter NMR-Messtechniken und der Auswertung ihrer Spektren wissenschaftlich beraten und wird dazu in deren Forschungsprojekte eingebunden. Eigene Forschungsarbeiten sind im Rahmen der zur Verfügung stehenden Arbeits- und Spektrometerzeit willkommen.

Einstellungsvoraussetzungen
Abgeschlossenes Chemiestudium, vorzugsweise spezialisiert auf Wirk- und Naturstoffchemie; mehrjährige Erfahrung in Bedienung und Wartung von NMR-Spektrometern inklusive des wissenschaftlichen und theoretischen Hintergrundes

Die Leibniz Universität Hannover will Frauen im Rahmen der gesetzlichen Vorschriften besonders fördern und fordert deshalb qualifizierte Frauen nachdrücklich auf, sich zu bewerben. Schwerbehinderte Bewerberinnen und Bewerber werden bei gleicher Qualifikation bevorzugt.

Bewerber melden sich bitte bis zum 31.05.2008 unter Einsendung der üblichen Unterlagen bei:

Prof. Dr. Helmut Duddeck
Leibniz Universität Hannover
Institut für Organische Chemie
Naturwissenschaftliche Fakultät
Schneiderberg 1B
30167 Hannover
Tel.: +49 (0)511 762-4615
Fax: +49 (0)511 762-4616
e-mail: duddeck@mbox.oci.uni-hannover.de

Job position at GE

Job Number: 1016545
Business: GE Corporate
Business Segment Global: Research
About Us: General Electric, a $152 bn
company present in over a hundred countries, is a
diversified business with the focus of translating imagination into
tangible ideas and products.

GE Global Research - Europe is GE's European technology hub specializing
in Energy, Oil & Gas, Sensor, and Healthcare technologies. Laboratories
represented are Alternative Energy and Environmental Technologies,
Hybrid & Renewable Energy Systems, High Power Electronics, Sensor
Technology, and Imaging Technologies Europe. Emerging technology areas
are Instrumentation, Composite Manufacturing Technology and
Biotechnology.

GE Global Research - Europe is one of the most attractive companies for
top talents in science and technology in Europe and employs highly
qualified scientists from around the globe. Researchers operate in
interdisciplinary teams, enjoy close business interaction and working in
the Center's "can-do" environment. Their enthusiasm provides a solid
foundation for leading and driving new projects, which in turn
translates into continual growth for the company.

GE is one of the Top Employers in Germany and ranks # 1 in the 2007
Handelsblatt Karriere Magazine survey in regards to Career Development.

Posted Position Title: MR Scientist (m/f)
Career Level: Experienced
Function: Engineering/Technology
Function Segment: Research - Physics
Location: Germany
City: Garching b. Munchen

Essential Responsibilities:
As an MR scientist, you will be developing new techniques and algorithms
in magnetic resonance imaging, magnetic resonance spectroscopy, or
functional magnetic resonance imaging. Broad goals of this position are
the improvement of image quality, development of new technology that
will enhance the MR system performance, clinical performance and
efficacy.

You will be expected to work independently and also within a larger team
to innovate and push the technical envelope in all aspects of magnetic
resonance imaging. You will have access to a state-of-the-art 3.0T whole
body MR scanner.

Your main responsibilities are:

* Apply knowledge and experience in MR physics to develop new
technological solutions for MR imaging
* Work with clinical partners to refine emerging technology for clinical
applications
* Maintain external visibility through conference presentations and
peer-reviewed publications

Qualifications/Requirements:

* A Ph.D. in Medical Physics, Electrical Engineering, Chemistry or
Biomedical Engineering or a Masters Degree in Medical Physics,
Electrical Engineering, Chemistry or Biomedical Engineering. At least 3
years experience in the field of magnetic resonance imaging (including
time in graduate school) is desired.
* A demonstrated record of research and development in MR imaging as
evidenced by conference proceedings and peer-reviewed publications
* Proficiency in programming of MR pulse sequences or image
reconstruction algorithms, and demonstrated expertise in MR physics.
* A strong foundation in MR systems architecture is required
* Proficiency in programming in C, simulation tools (MATLAB, IDL,
Mathematica, etc.).
* Excellent academic track record and proven scientific achievements
* Excellent communication skills
* Ability to work in a matrix environment
* Can-do attitude
* Open, creative & flexible
* Team-work & commitment
* Global mindset & customer focus
* Solution oriented & pragmatic
* Entrepreneurial mindset & acquisition expertise
* Fluency in English

Desired Characteristics:
* Basic knowledge in German

https://xjobs.brassring.com/1033/asp/tg/cim_jobdetail.asp?jobId=714210&PartnerId=54&SiteId=5346&type=mail&JobReqLang=1&recordstart=1&JobSiteId=5346&JobSiteInfo=714210_5346&gqid=0

Master, PhD and postdoctoral Positions in Gif-sur-Yvette, France

The biomolecular NMR research group of Dr. Eric Guittet (http://www.icsn.cnrs-gif.fr/guittet) at the Institut de Chimie des Substances Naturelles in Gif-sur-Yvette (France) is looking for Master and PhD students and postdocs from all nationalities.

Our laboratory uses modern NMR techniques to decipher the molecular mechanisms underlying biological functions for a variety of systems involving proteins such as enzymes, unfolded proteins and macromolecular complexes. We are also interested in structure-based drug design and in developing new methodology for protein NMR resonance assignment.

Three projects are currently under investigation in the lab:

- Structural and dynamics studies of small G-proteins Arfs: investigation of the GDP/GTP-bound switch mechanism and analyses of interactions with regulators and effectors. PI: Carine van Heijenoort.

- Structural and dynamics investigation of the C-terminal intrinsically disordered regulatory domain of the tyrosine kinase receptor ErbB2 (270aa): influence of proline rich regions and of tyrosine phosphorylation in disorder and local structuration and impact on its interactions with signalling partners. PI: Carine van Heijenoort.

- Investigation of the catalytic role of interdomain motion in the 75 kDa Cytochrome P450 Reductase in electron transfer from NADPH to Cytochrome P450. PI: Ewen Lescop.


Our lab hosts several high field liquid state NMR spectrometers including the recently installed 800MHz and 950 MHz and the solid state 700MHz. Our institute (ICSN) is located inside the CNRS campus mainly dedicated to biology. The campus is in the centre of Gif-sur-Yvette, a charming village with a countryside flavour, 45mn by train from the centre of Paris and belongs to the large scientific community located in the South-West of Paris, including Soleil synchrotron and Paris XI-Orsay University.

Highly motivated applicants that have a strong background in biochemistry and/or biophysics are invited to apply. Please contact eric.guittet@icsn.cnrs-gif.fr for more information and include a CV with a summary of research interests and accomplishments.

-------------------------------
Ewen LESCOP, PhD
Laboratoire de Chimie et Biologie Structurales
Institut de Chimie des Substances Naturelles - CNRS
1, avenue de la Terrasse
91190 Gif-sur-Yvette
France
Tél: 33-1-69-82-37-64
Fax: 33-1-69-82-37-84
-------------------------------

Postdoctoral Position at FSU & NHMFL

Open postdoctoral position in the application of NMR to Systems and Structural Biology at Florida State University and the National High Magnetic Field Laboratory

The Department of Chemistry and Biochemistry and the NHMFL are recruiting a postdoctoral fellow to work on solution NMR methods with application to metabolomics and structural biology.

Recently, advances have been made for resolution enhancement of multidimensional NMR spectra and the reduction of measurement time, including covariance NMR. These approaches will be further developed and applied for the quantitative and rapid analysis of complex biological mixtures and the improved interpretation of multidimensional NMR spectra of proteins. Tools resulting from this research will be integrated in the public COLMAR webportal (http://spinportal.magnet.fsu.edu).

The successful candidate has a strong background in one or several of the following areas: experimental or computational protein NMR, analytical NMR, or metabolomics.

Research will be performed in the new Chemical Sciences Laboratory at FSU and the NHMFL. The Department and the NHMFL provide a cross-disciplinary environment with training opportunities and modern facilities to carry out the research. The NMR facility includes solution NMR spectrometers between 500 and 900 MHz, including three that are equipped with cryogenic probes.

The position will be available starting in June 2009. If you are interested, please send your CV to Rafael Brüschweiler along with names and email addresses of 3 individuals who can be asked for a reference.


Rafael Brüschweiler
George M. Edgar Professor of Chemistry and Biochemistry
Chemical Sciences Laboratory and National High Magnetic Field Laboratory
Florida State University, Tallahassee, FL 32306
Phone: 850-644-1768
Fax: 850-644-8281
E-mail: bruschweiler@magnet.fsu.edu
Web-site: http://spin.magnet.fsu.edu

Postdoc in multinuclear MRI

DESCRIPTION:
We are seeking a highly motivated candidate for an NIH-funded post-doctoral position in multi-nuclear musculoskeletal MRI research in the Radiology Department of New York University School of Medicine.

The candidate will join the exiting and expanding Musculoskeletal Imaging Group in the Department of Radiology. The imaging group consists of 11 MSK radiologists. The candidate should have an excellent background in the application of NMR to biological models and understanding of the concepts of NMR physics and experimental NMR techniques. Experience in musculoskeletal MRI applications is an advantage. Our musculoskeletal research focused on the development of novel multinuclear MR methods at high & ultra-fields for assessment of functional integrity of musculoskeletal systems in general and articular cartilage in particular. The candidate will also have access to interact with the other researchers in the Hospital for Joint Diseases (HJD) and department of Chemistry who have number of ongoing projects related to arthritis. We are looking for a motivated person with experience in MRI to assist in this research program. There are opportunities to work closely with a dedicated musculoskeletal imaging basic scientist as well as a large group of diverse MR physicists and chemists.

FACILITY:
Our research facility includes several thousand square feet of dedicated research space, two state -of -the-art Siemens 3T Trio MR scanners and a 7T whole body MR system dedicated to research, as well as seven Siemens scanners used for clinical research, and a dedicated cartilage laboratory. A small bore system (9.4T) is also available at Department Chemistry for spectroscopy applications. The orthopedic and Rheumatology departments are among the largest and busiest in the country. The musculoskeletal MRI program is currently undergoing rapid expansion

QUALIFICATIONS:
Applicants must have an advanced degree (Ph.D) in Physical Science, Electrical, Biomedical Engineering or related field. The candidate must be familiar with computer operating systems and programming languages, particularly MatLab, C++, etc. Remuneration is competitive and commensurate with experience and will be based on New York University guidelines, Women and Minorities are encouraged to apply.

CONTACT:
Please forward your C.V. including a list of your publications, and the names/addresses of 3 references to:

Ravinder Regatte, PhD
Department of Radiology
NYU Medical Center
New York, NY 10016.
Ph. (212) 263-4857
E-mail: ravinder.regatte@med.nyu.edu

OR

Alexej Jerschow Ph.D.
Department of Chemistry
New York University
New York, NY 10003.
E-mail: alexej.jerschow@nyu.edu

PhD Zürich

Signaling via G-protein coupled receptors of high pharmacological importance. Despite its relevance little structural data are available for this class of membrane proteins. The aim of the project is to produce large fragments of GPCRs, and to study their structure but also their folding by NMR.
This ambitious project is very interdisciplinary. It includes techniques from molecular biology for recombinant expression of the membrane protein targets in isotopically enriched form. Good knowledge of biochemical working procedures is highly desired. The second emphasis will be placed on NMR spectroscopy as the primary (but not only) biophysical method to probe these interactions. Suitable candidates should have a diploma in (molecular) biology or (bio)-chemistry or a BSc/MSc in these subjects. Good knowledge in (membrane) protein expression/purification and interest in structural biology possibly with some computing know-how is highly desired. We offer good access to high-field NMR spectrometer (500 and 600 and 700 MHz, all with cryoprobes) and a well-equipped wet-lab during the PhD work. The group has experience in the field of membrane proteins, and is also collaborating with groups in the US.
The salary is based upon the Swiss National Science Foundation (SNF) salaries and covers approx. three-years of experimental work after which the experimental part of the PhD thesis should have been finished.

Starting date can be as early as 1st of July.

For further information you are encouraged to contact:
Prof. Oliver Zerbe
Institute of Organic Chemistry
University of Zurich
Winterthurerstr. 190
CH-8057 Zürich
Tel: 0041-44-635 42 63
e-mail: oliver.zerbe@oci.uzh.ch
http://www.oci.uzh.ch/group.pages/zerbe

Professor at Rennes

Professor at Rennes : molecular modeling, NMR constraints

Research:

The candidate will join the NMR - Interactions Lipides
Protéines team belonging to the CNRS UMR 6026. The research team area
focuses on structural modifications of peptide or protein interacting
with model membranes such as micelles or liposomes of various lipidic
compositions. The team is responsible of the NMR part of a magnetic
resonance platform of the University of Rennes and is involved in
structural studies of proteins by NMR.

The candidate will contribute to develop the use of molecular
modeling using NMR constraints. Interest and competence in studies in
lipidic environment is welcome.

Contact :
Arnaud BONDON
Equipe RMN-ILP, UMR CNRS 6026
PRISM, IFR 140
Université de Rennes 1, Campus de Villejean
CS 34317, 35043 Rennes cedex
Tel : (0)2 23 23 65 61
Email : arnaud.bondon@univ-rennes1.fr

Un poste de MCF l'Université de Versailles

Un poste de MCF est ouvert à l'Université de Versailles dans le groupe Tectospin de l'Institut Lavoisier de Versailles.

Description du poste:
MCF, N0 0807 Section CNU 33

Profil : Détermination structurale, RMN et Matériaux Nanoporeux.
Enseignement
Le candidat assurera des enseignements de chimie générale et inorganique et de spectroscopies en licence et en master Sciences et Technologies de l'université de Versailles-Saint-Quentin-en-Yvelines dans le cadre des enseignements généraux et/ou professionnels. Il lui sera également demandé de participer aux enseignements de la première année de préparation au concours des études médicales.
Recherche
La recherche se déroulera dans le groupe de RMN des solides de l'ILV, Tectopsin. Le développement des méthodes de cristallographie par RMN sera appliqué à la détermination structurale de matériaux nanoporeux, plus particulièrement des matériaux hybrides organiques-inorganiques (Metal-Organic Frameworks). Résolution structurale par diffraction, RMN et modélisation sera le thème principal de la recherche développée par le(a) candidat(e).
Contacts:
Recherche Francis Taulelle, taulelle@chimie.uvsq.fr, tel 01 39 25 44 77
Enseignement: Christine Greck, greck@chimie.uvsq.fr , tel 01 39 25 44 74
________________________________________________________
Dr. Francis Taulelle, Directeur de Recherche CNRS
Tectospin, Institut Lavoisier de Versailles, UMR 8180
Université de Versailles Saint Quentin en Yvelines
45 Avenue des Etats-Unis, 78035 Versailles Cedex
email: taulelle@chimie.uvsq.fr
Tel: 01 39 25 44 77 Fax:01 39 25 44 76