The position will be to work on an ANR funded project to perform in vivo laser-polarized 129Xe molecular imaging experiments. In this project, after optical pumping, laser-polarized xenon is encapsulated in cage-molecules functionalized with biological ligands and transported to the receptors of interest where it is imaged. The project involves collaboration with chemists (synthesis of cage-molecules of high affinity for xenon), biochemists (choice of the biological systems and of the ligands) and spectroscopists (handling of the hyperpolarized gas in fast imaging experiments).
The candidate will participate in the installation and optimization of the optical pumping setup designed to deliver high quantities of hyperpolarized xenon. He/she will be in charge of the spectroscopy and imaging experiments on small animals, in close collaboration with all partners. The MR experiments will be implemented on a 7T animal imager.
Applicants must have a doctorate degree in engineering (biomedical or chemical preferred), physics, chemistry, or other relevant discipline. Previous experience in NMR/MRI is desirable.
Interested individuals should e-mail their CV and the contact information of at least two recommenders to Luisa Ciobanu (luisa.ciobanu@cea.fr
Luisa Ciobanu
